• Title/Summary/Keyword: Direct Aging

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보성 삼베 연구 (Research on Hemp Fabrics Produced at Boseong)

  • 고부자
    • 복식문화연구
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    • 제12권1호
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    • pp.168-181
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    • 2004
  • This research on the present state of production and circulation of boseong-sambae, based on the materials, has been collected and arranged through the survey for one you, 2003. Boseong-sambae, the hemp fabric produced at Boseong, hold 35% of nationwide production volume and 50% of circulation volume. The products of hemp include hemp fabrics, shroud, contemporary Korean dresses and other household articles. Dried hemp skin, hemp thread and hemp fabrics are traded at the fair held in every five days, mostly by direct transactions which is trusted between the producers and consumers. A bolt of boseong-sambae includes 20 ja(a Korean foot, 60cm in length) of hemp fabrics in breadth of 35cm. The price of a bolt is approximately 2∼3 hundred thousand won. They are endeavoring to revive hemp fabric that the image was lost due to the cheap and coarse fabrics woven with Chinese thread since the latter half of 1990's. The advanced countries have invested positively in this business because hemp is an environment friendly material. Thus, a strong national support is demanded in this field facing a crisis due to the inundating of coarse hemp products from China, and the aging problem of the initiate, the reason of the discontinuation of the inherited technique. Through this research understanding tire present station and the problem of hemp production, the future research will be followed expecting the Renaissance of the Korean traditional hemp fabrics.

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Analysis of management status of chestnut cultivation in Chungcheongnam-do

  • Oh, Do Kyo;Ji, Dong Hyun;Kim, Se Bin
    • 농업과학연구
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    • 제48권3호
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    • pp.473-482
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    • 2021
  • In this study, we attempted to estimate the degree of management of chestnut forestry households in Chungcheongnam-do and to provide information for establishing chestnut cultivation-related policies. The chestnut management standard diagnostic table consists of three major categories, namely, management base, management and sales capacity, and production technology levels, along with 19 subcategories. A survey of 309 chestnut forestry households was conducted from 2014 to 2019 in Gongju, Cheongyang, and Buyeo in Chungcheongnam-do. The average score for the 19 subcategories was 65.7 points, indicating that these areas have excellent management conditions. When the total score was higher, the output per hectare and the rate of top-grade products in the total output were also higher, indicating a significant correlation. These findings will be useful for providing consulting services to chestnut growers as they highlight the correlation between the higher scores of the indicators in the chestnut management standard diagnostic table and the management performance of the farmers. We found that the scores of the indicators for management and sale skill, such as management record and analysis, material purchase, and direct transaction with consumers, were relatively lower than those of the indicators for management base and production skill. It is assumed that the chestnut growers aging has led to negligence in recording details on incomes, expenditures, and work and lowered the willingness to make substantial profits. Therefore, it is essential to overcome these problems for profitable chestnut farming.

Body Measurements for Designing Hip Dislocation Prevention Garment in Children with Cerebral Palsy

  • Lee, Ah Lam;Han, Hyunjung
    • 한국의류학회지
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    • 제46권3호
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    • pp.454-463
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    • 2022
  • This study aims to provide basic size data for the development of a hip dislocation prevention garment for cerebral palsy (CP) children and useful information for the design of garment products for CP children through identifying differences in body shape between CP and non-CP children and reviewing the tibial-stature prediction formulas of previous studies. Forty-seven Korean children with CP aged 2 to 14 years were measured for body size from October 2019 to August 2020. Body measurements of 18 sites, including greater trochanter length, which is an important site for a hip dislocation prevention garment, were collected and analyzed. Data of non-CP children were taken from same age of Size Korea and compared. Tibial-stature prediction formulas suggested in four previous studies were also reviewed. CP children had significantly lower stature as well as circumferential dimensions when compared to non-CP children. Greater trochanter length is difficult to predict through other body dimensions. Thus, direct measurement is required. Of the general key dimensions used in the clothing industry, only hip circumference could explain the body shape of CP children. Tibial-stature prediction formulas cannot always but tend to largely predict the actual stature of CP children.

Evaluating Staircase Safety Using BIM-based Virtual Simulation: Focusing on the Elderly in the Republic of Korea

  • Yang, Hyuncheul;Jeong, Kwangbok;Kim, Sohyun;Lee, Jaewook
    • 국제학술발표논문집
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    • The 9th International Conference on Construction Engineering and Project Management
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    • pp.1146-1153
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    • 2022
  • As the population is aging, accidents involving elderly people are also increasing (2014:11,667 persons; 2018: 11,797 persons). In the case of the elderly population, falling accidents are the primary direct or indirect causes of death; in particular, they face an elevated risk of staircase falls. This study proposes a method of evaluating the safety of staircases using Building Information Modeling (BIM)-based virtual simulation. By making a virtual user with the behavioral characteristics of the elderly respond to a staircase in a BIM model, its safety performance can be evaluated. The evaluation criteria were derived from regulations, elements, and characteristics relevant to the safety of staircases. To validate the proposed method, safety evaluation tests were simulated on actual staircases. The evaluation result of the test simulation shows the safety scores of 1.97 points for the elderly user and 2.95 points for the average male adult user against a required safety score of a minimum of 2 points. That is, safety is relative to users as the safety of the same staircase can be different depending upon the different behavioral characteristics of users. The study suggests that the risk of staircase-related fall accidents to the elderly can be reduced by improving staircase designs through the proposed method.

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봉독이 피부 노화에 미치는 영향 (The Effect of Bee Venom Therapy on Skin Aging)

  • 김진명;김윤범
    • 한방안이비인후피부과학회지
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    • 제23권2호
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    • pp.27-40
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    • 2010
  • Background and Objective : Increasing interest in anti-aging and anti-wrinkling agents for the skin has triggered the recent outflow of researches and studies in this field. This study was designed to investigate the effects of bee venom on skin wrinkling and skin aging by testing the skin wrinkling, skin elasticity, trans-epidermal water loss (TEWL), free radical level, anti-oxidative agent level, and skin tissue after infusion of bee venom on hairless mouse. Materials and Methods : Fifteen hairless mice aged between 36~40 weeks were divided randomly into 3 Group; the Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group. The Bee Venom Syringe Group were injected subcutaneously with bee venom (0.1cc in total) using an insulin syringe on three spots in the lumbar spine (one spot on the center and two spots 1~2cm to the side bilaterally). The Bee Venom Needle Group were pricked with bee venom-smeared acupuncture needles on three longitudinal spots in the lumbar spine each 1cm apart, after which the needles were removed 10 minutes later. The Control Group did not receive any form of intervention. All procedures took place thrice a week for four weeks, during which the mice were allowed free access to water and fodder. The mice were measured and compared in the weight, skin wrinkling scale, skin elasticity, and TEWL before and after the experiment. After the experiment, blood samples were taken to measure the free radical and anti-oxidative agent level, and the skin tissue was sliced for examination. Data was analyzed using the SPSS program (ver 12.0). The ANOVA analysis was used to compare and contrast the three groups, and t-test for paired samples was used to evaluate skin-wrinkling before and after experiment. The cut-off p-value of significance was set at p<0.05. Results : 1. Administration of bee venom did not cause serious weight loss or gain. 2. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed a decrease in skin wrinkling scale after intervention. Especially, the Bee Venom Syringe Group showed a significant decrease (p<0.05). 3. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed an increase in skin elasticity. Especially, the Bee Venom Syringe Group showed a significant increase (p<0.05). 4. No significant change in TEWL was found in the mice in all the three groups before and after experiment. 5. Free radical level was normal in all 15 mice in all the three groups, and anti-oxidative agent was not significantly different across the three groups. 6. The Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group did not show any significant difference in the thickness of epidermis and dermis, infiltration of inflammatory cells, and skin wrinkling. The epidermis layer was relatively better preserved in the Bee Venom Syringe Group as compared to the Bee Venom Needle Group and the control group. Conclusion : Direct injection of bee venom on the hairless mouse using a syringe was found to improve wrinkling of the skin and increase skin elasticity but did not show effectiveness on skin dryness due to water loss. The bee venom appears to have suppressive effects on skin wrinkling, one of the symptoms of skin aging, through a process independent of suppression of free radicals or increase of anti-oxidative agent.

레진시멘트의 색안정성에 대한 가속시험 (COLOR STABILITY OF THE RESIN CEMENTS WITH ACCELERATED AGING)

  • 송하정;박수정;황윤찬;오원만;황인남
    • Restorative Dentistry and Endodontics
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    • 제33권4호
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    • pp.389-396
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    • 2008
  • 본 연구는 레진 시멘트의 색 안정성을 평가하여, 레진 시멘트의 변색에 의한 심미 수복물의 실패의 가능성을 평가하고자 시행하였다. 4종의 이원중합형 레진 시멘트인 Panavia-F (PA, KURARAY), Duolink (DL; BISCO), Variolink II (VL; Ivoclar Vivadent), 및 RelyX Unicem (UC: 3M ESPE)과 1종의 자가중합형 레진 시멘트인 Resiment Ready-Mix (with fluoride) CE (RM: j.1.Blosser)를 사용하였으며, 대조군으로 복합레진 Gradia Direct (CD ; GC)과 복합 레진 인레이용 Tecera Dentin A3 (TE ; Bisco)를 사용했다. 각 재료 당 직경 6.5 mm, 두께 4.5 mm의 디스크형 시편 10개를 제작하였다. 중합 후 시편은 분광색채계측기인 Spectrolino (GretagMacbeth)를 이용해 CIE $L^*a^*b^*$값을 측정하고 가속시험을 위해 빛이 차단된 refrigerated bath circulator에서 60$^{\circ}C$ 증류수에 30일간 보관 후에 색 측정을 시행하고, 시험 전 후의 색차를 계산하였다. 가속 시험 후 $L^*$ 값은 감소하는 양상을 보였고, $a^*$ 값은 증가하는 양상을 보였지만 유의한 차이는 없었다. 반면 $b^*$ 값은 유의하게 증가하였다 (p < 0.05). TE가 15일과 30일 모두에서 가장 적은 색변화 (p < 0.05)를 보인 반면 GD는 15일 가속 실험 후 큰 색변화를 보였다. 30일 가속 실험 후 PA, VL, RM, DL 그리고 UC 순으로 ${\Delta}E^*$값이 커졌으며 (p < 0.05), 30일 후 모든 레진시멘트 들은 육안으로 변색을 인지 할 수 있는 3 이상의 ${\Delta}E^*$ 값을 보였다.

저온 및 고전류밀도 조건에서 전기도금된 구리 박막 간의 열-압착 직접 접합 (Thermal Compression of Copper-to-Copper Direct Bonding by Copper films Electrodeposited at Low Temperature and High Current Density)

  • 이채린;이진현;박기문;유봉영
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2018년도 춘계학술대회 논문집
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    • pp.102-102
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    • 2018
  • Electronic industry had required the finer size and the higher performance of the device. Therefore, 3-D die stacking technology such as TSV (through silicon via) and micro-bump had been used. Moreover, by the development of the 3-D die stacking technology, 3-D structure such as chip to chip (c2c) and chip to wafer (c2w) had become practicable. These technologies led to the appearance of HBM (high bandwidth memory). HBM was type of the memory, which is composed of several stacked layers of the memory chips. Each memory chips were connected by TSV and micro-bump. Thus, HBM had lower RC delay and higher performance of data processing than the conventional memory. Moreover, due to the development of the IT industry such as, AI (artificial intelligence), IOT (internet of things), and VR (virtual reality), the lower pitch size and the higher density were required to micro-electronics. Particularly, to obtain the fine pitch, some of the method such as copper pillar, nickel diffusion barrier, and tin-silver or tin-silver-copper based bump had been utillized. TCB (thermal compression bonding) and reflow process (thermal aging) were conventional method to bond between tin-silver or tin-silver-copper caps in the temperature range of 200 to 300 degrees. However, because of tin overflow which caused by higher operating temperature than melting point of Tin ($232^{\circ}C$), there would be the danger of bump bridge failure in fine-pitch bonding. Furthermore, regulating the phase of IMC (intermetallic compound) which was located between nickel diffusion barrier and bump, had a lot of problems. For example, an excess of kirkendall void which provides site of brittle fracture occurs at IMC layer after reflow process. The essential solution to reduce the difficulty of bump bonding process is copper to copper direct bonding below $300^{\circ}C$. In this study, in order to improve the problem of bump bonding process, copper to copper direct bonding was performed below $300^{\circ}C$. The driving force of bonding was the self-annealing properties of electrodeposited Cu with high defect density. The self-annealing property originated in high defect density and non-equilibrium grain boundaries at the triple junction. The electrodeposited Cu at high current density and low bath temperature was fabricated by electroplating on copper deposited silicon wafer. The copper-copper bonding experiments was conducted using thermal pressing machine. The condition of investigation such as thermal parameter and pressure parameter were varied to acquire proper bonded specimens. The bonded interface was characterized by SEM (scanning electron microscope) and OM (optical microscope). The density of grain boundary and defects were examined by TEM (transmission electron microscopy).

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Bacillus subtilis koji와 Rhizopus oryzae koji를 이용한 된장 및 간장의 키토올리고당 함량 증대 (Enhancement of Chitooligosaccharides in Doenjang (Soybean Paste) and Kanjang (Soy Sauce) using Bacillus subtilis Koji and Rhizopus oryzae Koji)

  • 음병욱;곽보연;김순영;손동화;이계호
    • 한국식품과학회지
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    • 제35권2호
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    • pp.291-296
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    • 2003
  • 된장 및 간장의 chitooligosaccharide(COS) 함량을 높이기 위해 Bacillus subtilis와 Rhizopus oryzae를 접종하여 koji를 만들고 이들 균주들에 의한 된장 및 간장에서 COS 함량변화에 대하여 알아보았다. COSM에 특이적인 항체를 이용하여 competitive direct ELISA(cdELISA)로 COS를 검출하였는데, 검출 감도는 $0.001{\sim}1{\mu}g/mL$이었고, 회수율은 된장 및 간장에서 각각 102%, 115%를 보였다. B. subtilis koji와 R. oryzae koji를 섞어 담근 된장 또는 간장(BR 된장 또는 간장)이 높은 COS 함량을 보였는데, 두 달 숙성에서 된장이 $171{\mu}g/g$, 간장이$29{\mu}g/mL$을 나타내었다. 일본, 국내 시판, 그리고 실험실에서 만든 된장 및 간장의 COS 함량을 비교해 본 결과, BR 시료구가 일본이나 국내 시판용보다 훨씬 높은 함량을 나타내 주어서 본 실험에서 koji 제조시 이용된 Bacillus subtilis와 Rhizopus oryzae 의해 COS의 함량을 높일 수 있는 가능성을 보여주었다.

면역학적 노화 기전에 관한 연구: T 및 B 세포의 변화 (Immunological mechanism of Aging : T & B cell changes)

  • 김재식;이원길;서장수;송경은;이중원;이난영
    • IMMUNE NETWORK
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    • 제1권3호
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    • pp.236-243
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    • 2001
  • Background: An immunological approach for aging mechanism appears to be important. Lymphocyte subsets analysis in peripheral blood is widely performed to assess the immune status and to diagnose and monitor various diseases. Some lymphocyte subsets are known to change with age, but only few data about age-related reference ragnes for these subsets in healthy individuals have been reported. So we attempted to report reference ranges for these subsets in each age group and review changes of the results with age for the secondary studies about immune cell function as lymphocyte blast transformation and immunoglobulin gene rearrangement (VDJ) including recombination activating genes (RAG-1 and RAG-2). Methods: Lymphocyte subset analysis was performed on 302 subjects, 189 males and 113 females with age group of all decades of life. Two color direct immunofluorescene flow cytometry (FCM) was done using $Simultest^{TM}$ IMK-Lymphocyte kit (Becton Dickinson, USA), $FACScan^{TM}$ (Becton Dickinson, USA) and $FACSCalibur^{TM}$ (Becton Dickinson, USA). Lymphocyte subsets analysed were T ($CD3^+$) and B cells ($CD19^+$), helper/inducer T ($CD4^+$) and suppressor/cytotoxic T cells ($CD8^+$), helper/suppressor ($CD4^+/CD8^+$) ratio and natural killer (NK) cells ($CD3^-CD16^+/CD56^+$). The absolute numbers of each subset were calculated from total lymphocyte counts. Data collected was analysed using SAS 6.12. A P-value of < 0.05 was considered significant. Results: We reported the counts and percentages of lymphocyte and these subsets in each age group. There were no statistically significant differences between male and female subjects. The percentage of $CD4^+$ T cells, and the count of NK cells did not show the significant difference among the various age groups. The age-related changes observed in our study were as following: 1) a decrease in the percentages of T cells, B cells and $CD8^+$ T cells ; 2) a decrease in the counts of B cells and $CD8^+$ T cells ; 3) an increase in the percentage and count of NK cells ; and 4) an increase in the $CD4^+/CD8^+$ ratio. Conclusion: The characteristics of aging process appeared to be showing a marked decrease of lympocyte subsets T and B cells as well as T8 ($CD8^+$). The age-related increase of the percentage of cells bearing NK marker can be interpreted as a compensatory consequence to cope with the decrease of T cells related to the thymic involution. These changes with age appeared to be for the secondary study about immune cell function as lymphocyte blast transformation and immunoglobulin gene rearrangement.

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서목태 주정 추출물이 DOPA 산화와 멜라닌 합성에 미치는 영향 (Effect of Rhynchosia Nulubilis Ethanolic Extract on DOPA Oxidation and Melanin Synthesis)

  • 김재련;김문무
    • 생명과학회지
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    • 제28권3호
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    • pp.331-338
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    • 2018
  • 멜라닌은 생체 내에서 발모 및 피부색을 결정하는데 중요한 역할을 하는 고분자 물질이다. 하지만 활성산소에 의해 과도하게 생성된 멜라닌은 노화와 관련된 기미, 주근깨와 과색소 침착증 등을 야기한다고 알려져 있다. 이와 관련된 천연물 중 서목태 성분의 하나인 polyphosphate는 자외선에 의해 손상되는 피부 노화를 억제한다고 보고되고 있다. 본 연구의 목적은 멜라닌 합성에 대한 RNEE의 직접적인 효과를 조사한 것이다. 본 연구에서 RNEE는 DPPH radical의 소거효과 및 환원력과 같은 항산화 효과는 없는 것으로 나타났다. MTT 실험을 수행한 결과, RNEE는 농도 의존적으로 세포독성을 증가시켰다. 또한, RNEE는 tyrosinase 활성과 DOPA-oxidation 실험 결과에서 멜라닌 합성을 증가시켰다. RNEE는 살아있는 세포에서 L-DOPA에 의한 유발되는 melanin생성 촉진 효과는 없는 것으로 나타났으나, 과산화수소를 처리하여 melanin 생성을 감소시킨 대조군과 비교시 과산화수소 전처리 후 RNEE를 처리한 군에서는 melanin 생성 촉진 효과가 있는 것으로 나타났다. 뿐만 아니라 RNEE는 tyrosinase related protein-2 (TRP-2)의 발현을 증가시키는 것으로 나타났으며, tyrosinase related protein-1 (TRP-1)의 단백질발현도 대조군과 비교시 $16{\mu}g/ml$의 농도에서 증가되는 것으로 나타났다. 특히 superoxide anion을 과산화수소로 변환시키는 SOD-3의 발현을 조사한 결과 $16{\mu}g/ml$ 이상의 농도에서 대조군과 양성 대조군인 ${\alpha}$-MSH보다 단백질 발현이 증가하는 것으로 나타났다. 그러므로, 이상의 결과는 서목태가 흑모와 관련 있는 멜라닌 생성을 촉진하는 기능적인 잠재성을 가지고 있다는 것을 암시한다.