• 한국응용곤충학회지
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• 제4권
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• pp.11-18
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• 1965

Phenylmercuric 8-Oxyquinolinate의 광범위한 식물병원균에 대한 살균작용, 식물의 수분증산억제작용, 식물에 대한 약해작용, Gas작용 및 자외선에 의한 경시변화에 관해 실험을 행하였으며, 그 결과를 요약하면 다음과 같다. (1) 포자발아억제작용은 P.M.A.보다 약간 불량한 결과를 보이며, 균사생장억제작용은 P.M.A. 보다도 양호하였다. (2) 식물의 수분증산억제작용은 초기에는 8-Hydroxyquinoline sulfate가 P.M.Q.보다도 강한 억제작용을 나타내었으나, 끝에 가서는 반대로 P.M.Q가 Oxine sulfate보다도 강한 작용을 나타냈다. (3) 수도종자의 발아, 발근에 미치는 영향은 P.M.A. 보다 약해가 적었고 수도 및 대두의 유식물의 경엽(40ppm 처리)에도 약해가 없었다. (4) 식불병원균에 대한 Gas효과에 의한 살균력은 P.M.A.보다 적었다. (5) 자외선에 의한 영향은 생물학적인 변화와 화학적인 변화가 거의 일치하였으며 P.M.Q.는 P.M.A.보다도 훨씬 자외선에 안정하였다. 이상의 결과로 보아 본약제는 광범위한 식물병원균에 대해 살균작용을 가지고 있고 식물의 수분증산도 억제시키며 이화학적인 안정성을 가진 유망한 살균제가 될 것으로 생각된다.

• 대한간호학회지
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• 제39권4호
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• pp.562-573
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• 2009

Purpose: The purpose of this study was to identify the effects on the cognitive function, Activities of Daily Living (ADL), mood, social behaviors, and problematic behaviors of robot pet-assisted program for elderly people with dementia. Methods: This study was a nonequivalent control group pretest-posttest design. The participants were 32 elders with dementia. Seventeen were assigned to the experimental group and 15 to the control group. The intervention was conducted twicea week for 6 weeks. Results: 1) After the program, cognitive function, ADL, and social behaviors did not show significant differences. 2) After the program, mood of experimental group was significantly better than that of the control group. 3) After the program, problematic behaviors of the experimental group were significantly more diminished than those of control group. 4) As a result of analyzing the response, robot pet-assisted program was effective such as inducing a positive emotional state and increasing communication and interaction. Conclusion: The robot pet-assisted program was effective in changing the mood and diminishing problematic behaviors and had positive effects such as increasing communication and interaction for elders with dementia. Therefore, this program should be considered as a positive program for physical and emotional support for elders with dementia.

• 한국미생물·생명공학회지
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• 제48권3호
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• pp.366-372
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• 2020

Since, side effects of antibiotics are frequently emphasized these days, their use is gradually diminishing, and alternative drugs are being developed. We have sought to reintroduce them as raw materials for human health as conventional 'weapons' that have been retired after their historical duties. In this study, we investigated the anti-inflammatory effects of lincomycin (LIN), on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Our findings show that LIN potently inhibited production of LPS-induced proinflammatory mediators, such as nitric oxide (NO) and prostaglandin E₂ (PGE₂), without cytotoxicity. Consistent with these findings, LIN strongly decreased protein expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX-2). Furthermore, LIN reduced pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-1β. To further elucidate the mechanisms of these inhibitory effects of LIN, we studied LPS-induced IκB-α degradation, and mitogen-activated protein kinase (MAPK) phosphorylation. LIN suppressed downregulation of inhibitory κB (IκB-α) degradation, and the phosphorylation of the c-Jun N-terminal kinase (JNK) pathway. Based on these results, we suggest that LIN may be considered a potential candidate as an anti-inflammatory cosmetic or a medicine for human health.

• 한국유체기계학회 논문집
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• 제10권6호
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• pp.38-43
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• 2007

Pumps for a turbopump generally operate under high rotational speeds and large head rise conditions. Therefore, reliability is a prime design requirement. Floating-ring type seals are frequently employed in a turbopump because of robustness despite of low hydraulic efficiency. There are many researches on the floating-ring seal itself, but the effects of the floating ring seals on the performance of the whole pump are not widely studied in spite of their importance. In the present study, experimental and computational studies on the effects of the radial clearance of the floating ring seals on the performance of a pump were performed. The experimental results showed that the head rise and efficiency increased as the floating-ring seal clearance was decreased. The results also showed the possibility that the leakage flow which was injected to the inlet of the inducer could enhance the suction performance of the inducer by diminishing the size of the backflows.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2009년 춘계학술대회논문집
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• pp.116-120
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• 2009

A two-dimensional unsteady inviscid flow solver has been developed for the simulation of complex geometric configurations on adaptive Cartesian meshes. Embedded condition was used for boundary condition and a predictor-corrector explicit time marching scheme was used for time-accurate numerical simulation. The Cartesian mesh generator, which was previously developed for steady problem, was used grid generation for unsteady flow. The solver was based on ALE formulation for body motion. For diminishing the effects of cut-cells, the cell merging method was used. Using cell merging method, it was eliminated the CFL constraints. The conservation problem, which is caused cell-type variation around region swept by solid boundary, was also solved using cell merging method. The results are presented for 2D circular cylinder and missile launching problem.

• Biomolecules & Therapeutics
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• 제2권3호
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• pp.281-285
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• 1994

Neutropenia is a major dose-limiting factor in cancer chemotherapy diminishing its usefulness and increase patient's susceptibility to infectious disease. Some recombinant human granulocyte colony stimulating factors(rhG-CSFs) are in use to reduce the risk of this serious side effect. In this study, we examined the pharmacological properties of DA-3030, a rhG-CSF expressed in E. coli. DA-3030 100 and $\mu\textrm{g}$/kg, i. v., had no significant effect on the central nervous, gastrointestinal system in mice and cardiovascular system in rabbits, but it slightly inhibited the spontaneous motility of isolated nonpregnant uterus in rats. It also had no influence on excretion of urinary electrolytes. DA-3030 administered for successive 3 days increased the blood WBC count in zymosan air pouch inflammed rats and in normal rats. These results indicate that DA-3030 has little side effects in animals.

• 소음진동
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• 제11권2호
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• pp.285-291
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• 2001

The impingement of a weak shock wane discharged from the open end of a shock tube upon a flat plate was investigated using shock tube experiments and numerical simulations. Harten-Yee Total Variation Diminishing method was used to solve axisymmetric, unsteady, compressible flow governing equations. Experiments were carried out to validate the present computations. The effects of the flat plate and baffle plate sizes on the impinging flow field over the flat plate were investigated. Shock Mach number was varied in the range from 1.05 to 1.20. The distance between the plate and shock tube was changed to investigate the effect on the peak pressure. From both the results of experiments and computations we obtained a good empirical equation to predict the peak pressure on the flat plate.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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• pp.519-522
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• 2006

Experimental and computational studies on an turbopump inducer with and without a bearing strut were performed to evaluate the effects of a strut on the performance of an inducer. Global performance data such as head rise and efficiency, and detailed flow characteristics such as surface static pressures were measured and compared with computational results. Generally a good agreement is observed between experimental and computational results, but some discrepancies are observed due to complex flow features such as backflows at the inlet and strut/inducer interactions. For the flow rates where the backflow region is large, installing a strut enhanced the hydraulic performance of the inducer by diminishing the size of the backflows. The results also show that the strut has negligible effect on the suction performance of the inducer.

• 한국게임학회 논문지
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• 제14권4호
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• pp.37-44
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• 2014

본 논문에서는 행동경제학에서 주로 사용되는 전망이론을 게임 인공지능 분야에 도입하여 인간의 인지적 특성을 사실적으로 표현하고자 하는 관점에서 NPC의 의사결정 모델을 제안한다. 이를 위하여 효용 이론의 한계로 지적되었던 기준점 설정의 문제, 민감도 체감성, 손실 회피의 특징을 분석하고, 이를 게임 상에서의 NPC 의사결정 모델에 반영한다. 본 논문에서는 제안 모델을 동적 지형분석에 적용하였으며, 실험을 통해 NPC의 다양한 개성 부과 및 창발적인 행위를 유도할 수 있음을 확인하였다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 추계학술대회논문집B
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• pp.562-567
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• 2000

The Impingement of a weak shock wave discharged from the open end of a shock tube upon a flat plate was investigated using shock tube experiments and numerical simulations. Harten-Yee Total Variation Diminishing method was used to solve axisymmetric, unsteady, compressible flow governing equations. Experiments were carried out to validate the present computations. The effects of the flat plate and baffle plate sizes on the impinging flow field over the flat plate were investigated. Shock Mach number was vaned in the range from 1.05 to 1.20. The distance between the plate and shock tube was changed to investigate the effect on the peak pressure. From both the results of experiments and computations we obtained a good empirical equation to predict the peak pressure on the flat plate.