• Journal of KIISE:Software and Applications
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• v.33 no.4
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• pp.365-377
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• 2006

Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein interaction is intrinsic to most cellular processes, prediction of protein interaction is an important issue in post-genomic biology where abundant interaction data have been produced by many research groups. In this paper, we present an associative feature mining method to predict implicit protein-protein interactions of Saccharomyces cerevisiae from public protein interaction data. We discretized continuous-valued features by maximal interdependence-based discretization approach. We also employed feature dimension reduction filter (FDRF) method which is based on the information theory to select optimal informative features, to boost prediction accuracy and overall mining speed, and to overcome the dimensionality problem of conventional data mining approaches. We used association rule discovery algorithm for associative feature and rule mining to predict protein interaction. Using the discovered associative feature we predicted implicit protein interactions which have not been observed in training data. According to the experimental results, the proposed method accomplished about 96.5% prediction accuracy with reduced computation time which is about 29.4% faster than conventional method with no feature filter in association rule mining.

• Journal of The Korean Association For Science Education
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• v.34 no.5
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• pp.499-510
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• 2014

The purpose of this research is to understand interactive learning during docent-led tours in a science museum focusing on scaffolding. We developed a scaffolding framework by collating the work of other researchers in related fields. The results show that scaffolding included three dimensions: purpose, interaction, and domain. The purpose dimension, divided into six categories, is related to the intention of the scaffolder and what the scaffolding are for: strategic, social, procedural, conceptual, verbal, and metacognitive. The interaction dimension reflects students' interaction with the scaffolder in two ways: dynamic (situation specific) and static (planned in advance). The domain dimension is related to two contents: domain-general and domain-specific (such as science). The scaffolding framework was applied to dynamic interactions between docents and visitors. The data was collected from elementary school students' family visits with the guidance of two docents at the Seodaemun Museum of Natural History. The data collected consisted of surveys, interviews, video-recordings, and transcripts. The analysis shows that five guiding contexts and scaffolding phases were recognized; 1) strategic scaffolding in a poorly illustrated exhibit; 2) conceptual scaffolding in a thoroughly explanative exhibit; 3) verbal scaffolding in misleading interpretation; 4) procedural scaffolding in a manipulative exhibit; and 5) metacognitive scaffolding with inaccurate content. In addition, the results show that the docents used the dynamic and static scaffolding synthetically so that the docent-led tour was effective. In conclusion, this study presents the usefulness of understanding visitors' science learning through the scaffolding framework, as well as the how docents can scaffold actively.

• Journal of the Korean GEO-environmental Society
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• v.5 no.1
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• pp.65-73
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• 2004

The analysis of corrugated steel pipes is depending on a second dimension frame analysis or compressed ring model. This is the analysis not to consider the behavior of soil-structure interaction. The behavior of load resistance system is varied according to the depth of cover and the spacing of corrugated steel pipes structure. Therefore, the behavior characteristic of corrugated steel pipes was confirmed through finite element analysis to consider the activity of soil-structure interaction. If soil cover is filled up to the more of optimal depth, behavior of corrugated steel pipes are similar to those of ductile steel pipes according to the earth pressure distribution and effects of traffic loads are decreased. But, If soil cover is filled up to the less of optimal depth, corrugated steel pipes can't behave completely as ductile steel pipes because the passive earth pressure acting on side of corrugated steel pipes is decreased according to the decrement of vertical earth pressure, and the traffic loads influence on the section forces is increased, so that the traffic loads dominated the behavior of corrugated steel pipes.

• Mass Spectrometry Letters
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• v.5 no.4
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• pp.95-103
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• 2014

Characterization and studies of proteome are challenging because biological samples are complex, with a wide dynamic range of abundance. At present the proteins are identified by digestion into peptides, with subsequent identification of the peptides by mass spectrometry (MS). MS is a powerful technique for the purpose, but it cannot identify every peptide in such complex mixtures simultaneously. For accurate analysis and quantification it is important to separate the peptides first by chromatography into fractions of a size that MS can handle. With these less complex fractions, the probability is increased of identifying peptides of low abundance that would otherwise experience ion suppression effects due to the presence of peptides of high abundance. Enrichment for peptides with certain post-translational modifications helps to increase their detection rates as well. Electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) is a mixed-mode chromatographic technique which combines the use of electrostatic repulsion and hydrophilic interaction. This review provides an overview of ERLIC and its various proteomics applications. ERLIC has been demonstrated to have good orthogonality to reverse phase liquid chromatography (RPLC), making it useful as a first dimension in multidimensional liquid chromatography (MDLC) and fractionation of digests in general. Peptides elute in order of their isoelectric points and polarity. ERLIC has also been successfully utilized for the enrichment for phosphopeptides and glycopeptides, facilitating their identification. In addition, it is promising for the study of peptide deamidation. ERLIC performs comparably well or better than established methods for these various applications, and serves as a viable and efficient workflow alternative.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.130-141
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• 2017

This study examined the effects of learners' job competency development on their vocational key competency improvement in lifelong education based on national competency standards. A survey was empirically carried out to 480 learners of lifelong education institutions in Seoul and the results were statistically analyzed. Covariance analysis was conducted to allow for external influences of lifelong education learners' educational environment in the process that verifies the effects of job competency development on vocational key competencies classified into 4 units, namely, mathematical skill, problem-solving skill, resource management skill, and communication skill. The findings are summarized as follows. First, all factors of job competency development had no effect on mathematical competency in the single dimension. Second, the testing of hypothesis 2 showed that education system(F=3.021, p<.05) and curriculum(F=6.684, p<.05) of job competency development factors had a significant positive effect on mathematical competency in the single dimension. Third, the testing of hypothesis 3 showed that only curriculum(F=5.865, p<.05) of job competency development factors had a significant positive effect on resource management in the single dimension. Fourth, the testing of hypothesis 4 showed that all factors of job competency development had no effect on communication in the single dimension. These findings suggest that the proper harmony of both education system and curriculum or all education system, curriculum and evaluation management in the combination of lifelong education support with teaching interaction can have a positive effect on the improvement of communication.

• Structural Engineering and Mechanics
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• v.20 no.2
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• pp.143-160
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• 2005

Modal analysis of cracked cantilever composite beams, made of graphite-fibre reinforced polyamide, is studied. By using the finite element and component mode synthesis methods, a numeric model applicable to investigate the vibration of cracked composite beams is developed. In this new approach, from the crack section, the composite beam separated into two parts coupled by a flexibility matrix taking into account the interaction forces. These forces are derived from the fracture mechanics theory as the inverse of the compliance matrix calculated with the proper stress intensity factors and strain energy release rate expressions. Numerical results are obtained for modal analysis of composite beams with a transverse non-propagating open crack, addressing the effects of the location and depth of the crack, and the volume fraction and orientation of the fibre on the natural frequencies and mode shapes. By means of modal data, the position and dimension of the defect can be found. The results of the study confirmed that presented method is suitable for the vibration analysis of cracked cantilever composite beams. Present technique can be easily extended to composite plates and shells.

• Journal of Korea Port Economic Association
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• v.22 no.1
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• pp.125-149
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• 2006

The main purpose of this study is to develop new measurement device of the quality of terminal service, applying the existing research output of service marketing to the specific industrial aspect of container terminal. Especially we tried to help marketing managers present the points of effective marketing strategy with each dimension of service quality. To achieve this aim, we defined the service quality demensions of container port as the following three ones; the internal, the external, and the interactive qualities. The applied measuring instruments could be divided into three dimensions by carrying out factor analysis. Additionally, by analyzing the relative effects of the three dimensions of service quality on customer satisfaction, we found that the relative importance are as follows; interaction quality>internal quality> external quality. We confirmed that the three dimensions of service quality could affect customer loyalty and information, through customer satisfaction.

• Macromolecular Research
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• v.8 no.6
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• pp.292-297
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• 2000

The theoretical synthesis of the isotactic and syndiotactic poly(methyl methacrylate) were carried out as a model for real polymerization reactions following the normal chain reaction processes by repeating the uniform localization of wave functions with inclusion of the interaction between the end group of the cluster and an attaching molecule by the elongation method, and then, the calculated value was compared with the usual PM$_3$ calculation. The results revealed that a reaction of cluster with monomer molecules has made it possible to calculate the electronic structure and total energy of polymer with nearly infinite length and a matrix of constant dimension. The isotactic poly(methyl methacrylate) is more stable than syndiotactic one. The same tendency have been found between the experimentally measured properties and a calculated total energy to explain the chain motion in isotatic and syndiotactic poly(methyl methacrylate).

• KIEAE Journal
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• v.4 no.2
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• pp.57-64
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• 2004

Apartments recently built have been strategically designed in many ways, and one of the most striking aspects is to utilize the idea of environmental friendliness and the application to the living environment. Especially, the number of environmentally friendly apartments that concern the health of residents have been increasing and their landscape is notably differentiated. The purpose of this research study was to examine the landscape of the environmentally friendly apartments that have been built in the past five years, and to assess its features in the aspects of therapeutic garden. Based upon the review of previous studies, this study constructed a checklist that was used to evaluate the planning components of the landscape during site visits. This study found that overall landscape selected in the study was well-planned. However, it was suggested that more features of therapeutic garden such as vegetation area which both encourages interaction with residents and produces therapeutic benefits be adopted in planning the advanced therapeutic garden of environmentally friendly apartments.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2012.10a
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• pp.534-537
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• 2012

Hydroelastic effects on sloshing phenomena in a rectangular tank are numerically investigated. The dimension of the tank is $1000mm{\times}600mm$, and the filling ratio of water is 20% of tank height. One of the side walls of tank is assumed to be flexible. The tank is excited into sway motion with amplitude of 100mm and frequency of 0.53Hz that is first natural frequency of water inside the tank. Prediction results for time histories of pressure and displacement of flexible and rigid walls are compared to quantitatively assess hydroelastic effects on sloshing phenomena.