• Title/Summary/Keyword: Dilution Factor

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Urine Concentration and the Adaptation of Renal Medullary Cells to Hypertonicity (소변농축과 장력 스트레스에 대한 콩팥 수질 세포들의 적응)

  • Kim, Dong-Un
    • Childhood Kidney Diseases
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    • v.11 no.2
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    • pp.145-151
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    • 2007
  • Hypertonicity (hypernatremia) of extracellular fluid causes water movement out of cells, while hypotonicity(hyponatremia) causes water movement into cells, resulting in cellular shrinkage or cellular swelling, respectively. In most part of the body, the osmolality of extracellular fluid is maintained within narrow range($285-295 mOsm/kgH_2O$) and some deviations from this range are not problematic in most tissue of the body except brain. On the other hand, the osmolality in the human renal medulla fluctuates between 50 and $1,200 mOsm/kgH_2O$ in the process of urine dilution and concentration. The adaptation of renal medullary cells to the wide fluctuations in extracellular tonicity is crucial for the cell survival. This review will summarize the mechanisms of urine concentration and the adaptation of renal medullary cells to the hyper tonicity, which is mediated by TonEBP transcription factor and its target gene products(UT-A1 urea transporter etc.).

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Mathematical Models for Optimal Bead Geometry for GMA Welding Process

  • Park, C.E.;Li, C.S.;Kim, I.S.
    • International Journal of Korean Welding Society
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    • v.3 no.1
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    • pp.8-16
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    • 2003
  • A major concern in Gas Metal Arc (GMA) welding process is the determination of welding process variables such as wire diameter, gas flow rate, welding speed, arc current and welding voltage and their effects on the desired weld bead dimensions and shape. To successfully accomplish this objective, 81 welded samples from mild steel AS 1204 flats adopting the bead-on-plate technique were employed in the experiment. The experimental results were used to develop a mathematical model to predict the magnitude of bead geometry as follows; weld bead width, weld bead height, weld bead penetration depth, weld penetration shape factor, weld reinforcement shape factor, weld bead total area, weld bead penetration area, weld bead reinforcement area, weld bead dilution, length of weld bead penetration boundary and length of weld bead reinforcement boundary, and to establish the relationships between weld process parameters and bead geomery. Multiple regression analysis was employed for investigating and modeling the GMA process and significance test techniques were applied for the interpretation of the experimental data.

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A Study on the Examination of Explosion Hazardous Area Applying Ventilation and Dilution (환기 및 희석을 적용한 폭발위험장소 검토에 관한 연구)

  • kim, Nam Suk;Lim, Jae Geun;Woo, In Sung
    • Journal of the Korean Institute of Gas
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    • v.22 no.4
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    • pp.27-31
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    • 2018
  • Classification of explosion hazard areas is very important in terms of cost and safety in the workplace handling flammable materials. This is because the radius of the hazardous area determines whether or not the explosion-proof equipment is installed in the electrical machinery and apparatus. From November 6, 2017, KS C IEC-60079-10-1: 2015 will be issued and applied as a new standard. It is important to understand and apply the difference between the existing standard and the new standard. Leakage coefficients and compression factors were added to the leakage calculation formula, and the formula of evaporation pool leakage, application of leakage ball size, and shape of explosion hazard area were applied. The range of the safety factor K has also been changed. Also, in the radius of the hazardous area, the existing standard applies the number of ventilation to the virtual volume, but the revised standard is calculated by using the leakage characteristic value. In this study, we investigated the differences from existing standards in terms of ventilation and dilution and examined the effect on the radius of the hazard area. Comparisons and analyzes were carried out by applying revised standards to workplaces where existing explosion hazard locations were selected. The results showed that even if the ventilation and dilution were successful, the risk radius was not substantially affected.

Thermal Ion Mass Spectrometry with Isotope Dilution Method: An application to Rare Earth Element Geochemistry (동위원소희석법을 이용한 열이온 질량분석: 희토류원소 지구화학에의 응용)

  • ;;;增田彰正
    • The Journal of the Petrological Society of Korea
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    • v.10 no.3
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    • pp.190-201
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    • 2001
  • Isotope Dilution Mass Spectrometry(IDMS) is one of the analytical method which uses enriched isotope spikes and analyzes the abundance of element by comparison of the spectrum between spiked mass and non-spike mass. Especially, the Thermal Ion Mass Spectrometry with isotope dilution technique (in general ID-TIMS) is the most accurate method of the chemical analysis, which enables us to obtain the data better than 1% in accuracy and precision. In IDMS, enriched isotope spike is one of the most important factor in order to obtain the best data. For rare earth elements, in general, a mixture of /sup 138/La, /sup 142/Ce, /sup 145/Nd, /sup 149/Sm, /sup 151/Sm, /sup 151/Eu, /sup 157/Gd, /sup 163/Dy, /sup 167/Er, /sup 171/Yb, and /sup 176/Lu is used as composite spike. IDMS is very useful in geochronology and REE geochemistry. Especially, it is very effective in studying the “tetrad effect” of rare earth elements in natural samples.

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Quantifying Uncertainty of Calcium Determination in Infant Formula by AAS and ICP-AES (AAS 및 ICP-AES에 의한 조제분유 중 칼슘 함량 분석의 측정불확도 산정)

  • Jun, Jang-Young;Kwak, Byung-Man;Ahn, Jang-Hyuk;Kong, Un-Young
    • Korean Journal of Food Science and Technology
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    • v.36 no.5
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    • pp.701-710
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    • 2004
  • Uncertainty was quantified to evaluate calcium determination result in infant formula with AAS (Atomic Absorption Spectrometry) and ICP-AES (Inductively Coupled Plasma-Atomic Emission Spectrometry). Uncertainty sources in measurand, such as sample weight, final volume of sample, sample dilution and the instrumental result were identified and used as parameters for combined standard uncertainty based on the GUM (Guide to the expression of uncertainty in measurement) and Draft EURACHEM/CITAC Guide. Uncertainty components of each sources in measurand were identified as resolution, reproducibility and stability of chemical balance, standard material purity, standard material molecular weight, standard solution concentration, standard solution dilution factor, sample dilution factor, calibration curve, recovery, instrumental precision, reproducibility, and stability, Each uncertainty components were evaluated by uncertainty types and included to calculate combined uncertainty. The kinds of uncertainty sources and components in the analytical method by AAS and ICP-AES were same except sample dilution factor for AAS. The analytical results and combined standard uncertainties of calcium content were estimated within the certification range $(367{\pm}20\;mg/100g)$ of CRM (Certified Reference Material) and were not significantly different between method by AAS followed by ashing and method by ICP-AES followed by acid digestion as $359.52{\pm}23.61\;mg/100g\;and\;354.75{\pm}16.16\;mg/100g$, respectively. Identifying uncertainty sources related with precision, repeatability, stability, and maintaining proper instrumental conditions as well as personal proficiency was needed to reduce analytical error.

Effects of Contrast Agent Concentration on the Signal Intensity and Turbo Factor of TSE and Slice-selective IR in T1-weighted Contrast Imaging

  • Han, Yong Soo;Lee, Soo Chul;Lee, Dong Yong;Choi, Jiwon;Lee, Jong Woong;Kweon, Dae Cheol
    • Journal of Magnetics
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    • v.21 no.1
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    • pp.115-124
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    • 2016
  • The present study analyzes T1 TSE and T1 slice sel. IR (dark_fluid) signal strength according to the degree of gadolinium contrast agent dilution and analyzes the turbo factors with regard to changes in the maximum and overall signal strength to study correlations between changes and signal-to-noise ratios (SNRs) and compare peak-to-peak SNR (PSNR) enhancement in order to improve the quality of T1-weighted images. Enhancement TR (600 msec) evaluated to determine the T1 TSE turbo factor and obtain the maximum signal strength, T1WI were used sequentially to experiment with turbo factors_1-4. T1 slice sel. IR (dark-fluid) was used to sequentially test turbo factors_2-5 but not turbo factor_1 at a TR (1500 msec) and compare data at an increase in T1 of 900 msec. The T1 TSE was reduced according to the contrast agent concentration. Phantom signal strength increased, whereas turbo factors_1-4 exhibited maximum signal strength at a concentration of 3 mmol, followed by a gradual decrease. In the turbo factors_2-5, the signal strength increased sharply to maximum signal strength at 0.7 mmol, followed by a reduction. T1 TSE had a greater maximum signal strength than did T1 slice sel. IR (dark_fluid). A comparison of SNR found that T1 TSE imaging was superior (33.3 dB) in turbo factor_1 and T1 slice sel. IR (dark_fluid) was highest (33.9 dB) at turbo factor_5. A PSNR comparison analysis was not sufficient to distinguish between the images obtained with both techniques at 30 dB or higher under all experimental conditions.

Trace metals in Chun-su Bay sediments (천수만 퇴적물에서 미량금속의 지화학적 특성)

  • Song, Yun-Ho;Choi, Man-Sik;Ahn, Yun-Woo
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.16 no.4
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    • pp.169-179
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    • 2011
  • To investigate the controlling factor and accumulation of trace metal concentrations in Chun-su Bay sediments, grain-size, specific surface area, organic carbon content, calcium carbonate content, and concentration of Al, Fe, Na, K, Mg, Ca, Ti, Mn, P, S, Ba, Sr, Li, Co, Cr, Ni, Cu, Zn, As, Cd, Cs, Sc, V, Sn were analyzed. Controlling factors of metals were quartz-dilution, calcium carbonate and coarse sand or K-feldspar. Although the distribution of V, Co, Cr, Ni, Cu, Zn, Sn, and Cd concentration was explained by grain-size effiect, Mn and As showed the similar importance of grain-size effect and coarse sand or K-feldspar factors. By virtue of enrichment factor and 1 M HCl experiment, there were little enrichment in all the trace metals in bay sediments, which were explained well by geochemical properties of sediments. Since the concentration levels of As in coarse sand were high as much as those in fine-grained sediments and it was combined with Mn oxide (1 M HCl leached) and K-feldspar (residual), it was suggested that when the enrichment of As in sediments would be assessed, it is necessary to separate the coarse sand from bulk sediments or to use only sediments with higher than 10% in < $16{\mu}m$ fraction.

Estimating Saturation-paste Electrical Conductivities of Rose-cultivated Soils from their Diluted Soil Extracts (절화장미 재배토양에서 희석된 토양 침출용액으로부터 포화반죽 전기전도도 추정)

  • Lee, In-Bog;Ro, Hee-Myong;Lim, Jae-Hyun;Yiem, Myoung-Soon
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.6
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    • pp.398-404
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    • 2000
  • We examined the effect of soil:water ratio on the equivalent concentration of individual electrolyte species and the electrical conductivities (EC) of the diluted extracts of 24 soil samples (loam or silt loam) collected from rose-cultivated plastic houses to estimate the EC of saturated soil-paste extracts (ECe) from diluted soil extracts. With increasing volume ratio of water (higher dilution), the equivalent concentrations of each electrolyte species and their sum increased. The relative contribution to the EC, however, was highest for $NO_3{^-}$, irrespective of soil:water ratio. The measured ECe was 6.36 for loam and $8.09dS\;m^{-1}$ for silt loam soils and the corresponding soil:water ratio was 0.38 and 0.50, respectively. The EC_e estimated from the EC of diluted extracts at 1:1, 1:2, or 1:5 soil:water ratios using their corresponding uniform diluted factors was lower than the measured EC_e and this difference was greater with higher dilution and EC values. Therefore, the alternative diluted factors (y) for each soil: water ratio were obtained following the definition of diluted factor and were correlated significantly with volume ratios of added water (x): y=1.55x+0.5 for loam and y=1.21x+0.48 for silt loam soils. On the other hand, correlation analyses of the EC of soil extracts (y) to the volume ratio of added water (x) on log-log scale yielded linear models: logy = -0.805logx + logb, SD of slope=0.05, b=sample specific constant, n=24). With known saturation percentage of a sample representing a group and and the EC of diluted extract of a given soil, the EC_e could be predicted using the proposed logarithmic equation.

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Performance Test of A Reverse-Annular Type Combustor (TS2) for APU (보조동력장치용 환형 역류형 연소기 (TS2) 성능 시험)

  • Ko, Young-Sung;Han, Yeoung-Min;Lee, Kang-Yeop;Yang, Soo-Seok;Lee, Dae-Sung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.26 no.6
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    • pp.805-810
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    • 2002
  • Development of a small gas-turbine combustor for 100㎾ class APU(Auxiliary Power Unit) has been performed. This combustor is a reverse-annular type and has a tangential swiller in the liner head to improve the fuel/air mixing and flame stability. Three main and three pilot fuel injectors of the simplex pressure-swirl type are used. The performance target at the design condition includes a turbine inlet temperature of l170k, a combustion efficiency of 99%, a pattern factor of 30%, and an engine durability of 3000 hours. Under developing the combustor, we conducted the performance test of our first prototype(TS1) with some variants. As a result of the test, the performance targets of the combustor are satisfied except that the pattern factor is about 4% higher than the target value. Therefore, the second prototype(TS2) was redesigned and the performance test was conducted with the critical focus on the pattern factor and the exit mean temperature. We adopted TS2 four variants to check the improvement of the pattern factor. As a result, the pattern factors of several variants were satisfied with the performance target. Finally, the TS2A variant was chosen as a final combustor fur our APU model.

The Performance Evaluation of a Gas Turbine Combustor (가스터빈 연소기의 성능평가)

  • Ahn, Kook-Young;Kim, Han-Seok;Ahn, Jin-Hyuk;Pae, Hyoung-Su
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.10
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    • pp.1294-1299
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    • 2000
  • The combustion characteristics have been investigated to develop the 50 kW-class gas turbine combustor. The combustor design program was developed and applied to design this combustor. The combustion air which has the temperature of 45, 200, $300^{\circ}C$ were supplied to combustor for elucidating the effect of inlet air temperature on CO, NOx emissions and flame temperature. The exit temperature and NO were increased and CO was decreased with increasing inlet air temperature. Also, the effect of equivalence ratio was considered to verify the combustor performance. The emissions of CO and NO with inlet air temperature can be analyzed qualitatively by measuring the temperature inside the combustor. The combustion performance with fuel schedule was evaluated to get the informations of the starting and part loading process of gas turbine. The combustion was stable above the equivalence ratio of 0.18. The pattern factor which is the important parameter of combustor performance was satisfied with the design criterion. Consequently the combustor was proved to meet the performance goal required for the target gas turbine system.