• Journal of Ginseng Research
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• 제27권3호
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• pp.120-128
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• 2003

Alternative medicines such as herbal products are increasingly being used for preventive and therapeutic purposes. Ginseng is the best known and most popular herbal medicine used worldwide. In spite of some beneficial effects of ginseng on the nervous system, little scientific evidence shows at the cellular level. In the present study, I have examined the direct modulation of ginseng total saponins and individual ginsenosides on the activation of $Ca^{2+}$ channels and NMDA-gated channels in cultured rat dorsal root ganglion (DRG) and hippocampal neurons, respectively. In DRG neurons, application of ginseng total saponins suppressed high-voltage-activated $Ca^{2+}$ channel currents and ginsenoside Rg$_3$, among the 11 ginsenosides tested, produced the strongest inhibition on $Ca^{2+}$ channel currents. Occlusion experiments using selective $Ca^{2+}$ channel blockers revealed that ginsenoside Rg$_3$ could modulate L-, N-, and P/Q-type currents. In addition, ginsenoside Rg$_3$ also proved to be an active component of ginseng actions on NMDA receptors in cultured hippocampal neurons. Application of ginsenoside Rg$_3$ suppressed NMDA-induced [Ca$^{2+}$]$_{i}$ increase and -gated channels using fura-2-based digital imaging and patch-clamp techniques, respectively. These results suggest that the modulation of $Ca^{2+}$ channels and NMDA receptors by ginsenoside Rg$_3$ could be part of the pharmacological basis of ginseng actions in the peripheral and central nervous systems.ous systems.

• 대한지리학회지
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• 제44권2호
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• pp.105-121
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• 2009

지형 굴곡이 심한 하와이 화산섬의 경우, 측후소 분포가 매우 제한적이어서 공식적인 기온 분포도가 작성되지 못하고 있는 실정이다. 본 연구에서는 이러한 기온 지도화의 문제점을 해결하는 방법으로 위성기반의 지표온도 자료로부터 기온추정치를 추출하여 내삽법에 필요한 입력자료로 사용하였다. 추출된 온도값을 표본값으로하여 거리 역비례 가중치법(IDW)과 공동크리깅 (cokriging)을 적용하여 기온추정치를 지도화하였다. 기온과 고도값을 함께 이용한 cokriging이 IDW에 비해 크게 향상된 추정 오차값을 나타내었다. Cokriging은 주 변수와 고도와 같은 추가 변수 간의 상관관계가 유의하게 나타날 때 효과적으로 사용되는 내삽법이지만, 내삽 정확도는 계절적인 기상조건에 민감하게 영향받는 것으로 조사되었다. 강수량이 크게 증가하는 우기에는 건기에 비해 공간적인 기온변화가 크며, 이에 따라 기온 추정 오차값도 우기에 높게 나타났다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제1권4호
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• pp.239-247
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• 2001

The Fluorescence-Activated Cell Sorter (FACS) is a well-established instrument used for identifying, enumerating, classifying and sorting cells by their physical and optical characteristics. For a miniaturized FACS device, a disposable plastic microchip has been developed which has a hydrodynamic focusing chamber using soft lithography. As the characteristics of the spatially confined sample stream have an effect on sample throughput, detection efficiency, and the accuracy of cell sorting, systematic fluid dynamic studies are required. Flow visualization is conducted with a laser scanning confocal microscopy (LSCM), and three-dimensional flow structure of the focused sample stream is reconstructed from 2D slices acquired at $1\mutextrm{m}$ intervals in depth. It was observed that the flow structure in the focusing chamber is skewed by unsymmetrical velocity profile arising from trapezoidal cross section of the microchannel. For a quantitative analysis of a microscopic flow structure, Confocal Micro-PIV system has been developed to evaluate the accelerated flow field in the focusing chamber. This study proposes a method which defines the depth of the measurement volume using a detection pinhole. The trajectories of red blood cells (RBCs) and their interactions with surrounding flow field in the squeezed sample stream are evaluated to find optimal shape of the focusing chamber and fluid manipulation scheme for stable cell transporting, efficient detection, and sorting

• 한국운동역학회지
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• 제13권3호
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• pp.265-276
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• 2003

The objective of this research is to provide basic data for improving athletic performances, suggesting methods that can be utilized at games and coaching movements in the snatch, by analyzing the level of contribution of muscles to the movements of the snatch lift through three-dimensional imaging and EMG analysis between skilled and unskilled lifters. To this end, three high school students (the skilled group), three middle school student (the unskilled group) were selected; two digital video cameras and electromyography were used. The muscles measured by an EMG include gastrocnemius muscle, biceps femoris muscle, erector spinae, latissimus dorsi muscle, trapezius muscle, and brachioradialis. Based on the Ariel Performance Analysis System (APAS) program, the results of the analysis are summarized as follows. 1. In performing snatch pulls, the skilled lifters were found to simultaneously move the weight centers of the body and the barbell close to vertical, close to the shoulders in the pulling portion; in snatching and grabbing the barbell from a sited position, it was observed that the shorter the time for adjusting to change in the height of the barbell by using rotational inertia, the better it is to perform the movements. 2. The skilled lifters were observed to perform stable and efficient movements in grabbing the bar in a sited position, by moving the barbell and weight center of the body close to vertical and moving the shoulder joint under the bar fast. 3. The results of the EMG analysis of the entire movements from the snatching portion to the portion of grabbing the bar in a sited position show that when the skilled lifters lifted the barbell vertically during the pulling portion, their shoulder joints were extended to put more weight on biceps femoris muscle and brachioradialis; and in snatching and grabbing the bar from a sited position, it was found desirable to increase the myoelectrical activity of erector spinae in order to achieve a balance in the movements of the hip joint between font and rear, as the weight centers of the body and the barbell move higher. On the other hand, the unskilled lifters were found that in response to change in posture, they increase their muscular strength inefficiently in performing the movements throughout the entire lifting process.

• 한국항행학회논문지
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• 제19권6호
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• pp.484-491
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• 2015

항공영상은 디지털 광학 영상 기술의 성장과 무인기(UAV)의 발달로 인하여 영상의 도입 및 공급이 크게 증가하였고, 이러한 항공영상 데이터를 기반으로 지상의 속성 추출, 분류, 변화탐지, 영상 융합, 지도 제작 형태로 활용되고 있다. 특히, 영상분석 및 활용에 있어 딥 러닝 알고리즘은 패턴인식 분야의 한계를 극복하는 새로운 패러다임을 보여주고 있다. 본 논문은 딥 러닝 알고리즘인 ConvNet기반으로 항공영상의 영역분할 및 분류 결과를 통한 더욱더 넓은 범위와 다양한 분야에 적용할 수 있는 가능성을 제시한다. 학습데이터는 도로, 건물, 평지, 숲 총 3000개 4-클래스로 구축하였고 클래스 별로 일정한 패턴을 가지고 있어 특징 벡터맵을 통한 결과가 서로 다르게 나옴을 확인할 수 있다. 본 연구의 알고리즘은 크게 두 가지로 구성 되어 있는데 특징추출은 ConvNet기반으로 2개의 층을 쌓았고, 분류 및 학습과정으로 다층 퍼셉트론과 로지스틱회귀 알고리즘을 활용하여 특징들을 분류 및 학습시켰다.

• 한국농공학회논문집
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• 제49권5호
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• pp.67-77
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• 2007

The images of MODerate resolution Imaging Spectroradiometer (MODIS) that provide wider swath and shorter revisit frequency than Land Satellite (Landsat) and Satellite Pour I' Observation de la Terre (SPOT) has been used fer land cover classification with better spatial resolution than National Oceanic and Atmosphere Administration/Advanced Very High Resolution Radiometer (NOAA/AVHRR)'s images. Due to the advantages of MODIS, several researches have conducted, however the results for the land cover classification using MODIS images have less accuracy of classification in small areas because of low spatial resolution. In this study, uncertainty of paddy fields classification using MODIS images was conducted in the region of Gyeonggi-do and the relation between this uncertainty of estimating paddy fields and topographical factors was also explained. The accuracy of classified paddy fields was compared with the land cover map of Environmental Geographic Information System (EGIS) in 2001 classified using Landsat images. Uncertainty of paddy fields classification was analyzed about the elevation and slope from the 30m resolution Digital Elevation Model (DEM) provided in EGIS. As a result of paddy classification, user's accuracy was about 41.5% and producer's accuracy was 57.6%. About 59% extracted paddy fields represented over 50 uncertainty in one hundred scale and about 18% extracted paddy fields showed 100 uncertainty. It is considered that several land covers mixed in a MODIS pixel influenced on extracted results and most classified paddy fields were distributed through elevation I, II and slope A region.

• 치과방사선
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• 제24권2호
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• pp.361-368
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• 1994

Radiographic planning is needed for implant placement in order to determine implant length, jaw bone volume, anatomical stucture and so on. Radiographic examination includes conventional radiography, conventional tomography and CT scan. The most accurate mesurement can be obtained from CT scan. For the cross-sectional view of mandible, CT scan reconstruction is generally needed. But the cross-sectional view of mandible can be reformed by personal computer. This study was performed to examine the clinical usefulness of reformed image using personal computer in comparison with CT scan reconstructed image. CT axial slices of 4 mandibles of 4 volunteers were used. Digital imaging system was composed of Macintosh Ⅱ ci computer, high resolution Sony XC-77 CCD camera, Quick Capture frame grabber board and 'NIH Image' program. Seven reconstructed cross-sectional images within CT machine(CT group) were obtained. And seven reformed cross-sectional images(PC group) after digitization of CT axial slices into the personal computer were obtained. PC group was compared with CT group in the objective and subjective aspects. The results were as follow: 1. Measurement of mandibular height & width in both group showed insignificant difference(P>0.05). 2. Subjective assessment of the mandibular canal in both group showed insignificant difference(P>0.05). 3. Image reformation using personal computer could provide panoramic view, which could not be obtained in CT scan reconstruction.

• 대한기계학회논문집B
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• 제40권4호
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• pp.221-226
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• 2016

하지혈관에 비해 상지혈관질환은 드물기 때문에 상지혈관계에 대한 실험적, 수치해석적 연구는 매우 드물다. 본 논문에서는 최초로 MRA 영상데이터로부터 한국 성인 왼팔의 혈관계, 상완동맥에서 1 mm 이상의 손가락동맥들에 이르는, 3차원 컴퓨터 모델을 제작하였다. 이 모델에 대해 수치해석을 수행하여 정상, 주기유동에 대한 속도장, 압력장을 계산하였고 주요 분지관에서의 유량분배와 벽전단응력 분포에 대해 분석하였다.

• 대한한의학회지
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• 제19권2호
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• pp.271-295
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• 1998

This study was performed from October 1997 to March 1998 on 42 healthy students to observe the effects of acupuncture at Hap-kok (LI4) according to the meridian and qi-xue(氣血) phenomenon of oriental medicine's theory. Skin temperature on the Kok-Chi(LI11) and Yong-Hyang(LI20) were measured by D. I. T. I. (Digital Infrared Thermograph Imaging) before acupuncture stimulation, 1min after and after acupuncture stimulation during 10 min. 1. In healthful man, average skin temperature about Kok-Chi area was in low than Yong-Hyang, and temperature change for 10 min was decreased significantly. 2. In Kok-Chi, the temperature decrease index of execution was shown in low than control. 3. When the temperature of Yong-Hyang(left) was higher, the index was shown in high than control. 4. When the temperature of Kok-Chi (left) was higher, execution temperature change was decreased significantly than control. The above results indicates that D. I. T. I. was a useful method to observe follow-up the effects and changes by acupuncture stimulation on objective evaluation of phenomenon for the meridian system. Thus, acupuncture on LI4 affects to thermal changes of ST25 and LI4, but exact examination of thermal changes on ST25 will have to be.

• Journal of the Optical Society of Korea
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• 제19권2호
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• pp.136-143
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• 2015

Image deblurring by a deconvolution method requires accurate knowledge of the blur kernel. Existing point spread function (PSF) models in the literature corresponding to lens aberrations and defocus are either parameterized and spatially invariant or spatially varying but discretely defined. In this paper, a parameterized model is developed and presented for a PSF which is spatially varying due to lens aberrations and defocus in an imaging system. The model is established from the Seidel third-order aberration coefficient and the Hu moment. A skew normal Gauss model is selected for parameterized PSF geometry structure. The accuracy of the model is demonstrated with simulations and measurements for a defocused infrared camera and a single spherical lens digital camera. Compared with optical software Code V, the visual results of two optical systems validate our analysis and proposed method in size, shape and direction. Quantitative evaluation results reveal the excellent accuracy of the blur kernel model.