• The Korean Journal of Physiology and Pharmacology
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• v.14 no.1
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• pp.21-28
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• 2010

Phenolic compounds affect intracellular free $Ca^{2+}$ concentration ($[Ca^{2+}]_i$) signaling. The study examined whether the simple phenolic compound octyl gallate affects ATP-induced $Ca^{2+}$ signaling in PC12 cells using fura-2-based digital $Ca^{2+}$ imaging and whole-cell patch clamping. Treatment with ATP ($100\;{\mu}M$) for 90 s induced increases in $[Ca^{2+}]_i$ in PC12 cells. Pretreatment with octyl gallate (100 nM to $20\;{\mu}M$) for 10 min inhibited the ATP-induced $[Ca^{2+}]_i$ response in a concentration-dependent manner ($IC_{50}=2.84\;{\mu}M$). Treatment with octyl gallate ($3\;{\mu}M$) for 10 min significantly inhibited the ATP-induced response following the removal of extracellular $Ca^{2+}$ with nominally $Ca^{2+}$-free HEPES HBSS or depletion of intracellular $Ca^{2+}$ stores with thapsigargin ($1\;{\mu}M$). Treatment for 10 min with the L-type $Ca^{2+}$ channel antagonist nimodipine ($1\;{\mu}M$) significantly inhibited the ATP-induced $[Ca^{2+}]_i$ increase, and treatment with octyl gallate further inhibited the ATP-induced response. Treatment with octyl gallate significantly inhibited the $[Ca^{2+}]_i$ increase induced by 50 mM KCI. Pretreatment with protein kinase C inhibitors staurosporin (100 nM) and GF109203X (300 nM), or the tyrosine kinase inhibitor genistein ($50\;{\mu}M$) did not significantly affect the inhibitory effects of octyl gallate on the ATP-induced response. Treatment with octyl gallate markedly inhibited the ATP-induced currents. Therefore, we conclude that octyl gallate inhibits ATP-induced $[Ca^{2+}]_i$ increase in PC12 cells by inhibiting both non-selective P2X receptor-mediated influx of $Ca^{2+}$ from extracellular space and P2Y receptor-induced release of $Ca^{2+}$ from intracellular stores in protein kinase-independent manner. In addition, octyl gallate inhibits the ATP-induced $Ca^{2+}$ responses by inhibiting the secondary activation of voltage-gated $Ca^{2+}$ channels.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.12
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• pp.1340-1350
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• 2009

The design and implementation of planar Active Phased Array Antenna System are described in this paper. This Antenna system operates at X-band with its bandwidth 10 % and dual polarization is realized using dual slot feeding microstrip patch antenna and SPDT(Single Pole Double Through) switch. Array Structure is $16\times16$ triangular lattice structure and each array is composed of TR(Transmit & Receive) module with more than 40 dBm power. Each TR module includes digital attenuator and phase shifter so that antenna beam can be electronically steered over a scan angle$({\pm}60^{\circ})$. Measurement of antenna pattern is conducted using a near field chamber and the results coincide with the expected beam pattern. From these results, it can be convinced that this antenna can be used with control of beam steering and beam shaping.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.5
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• pp.619-628
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• 2009

LiDAR has capability of rapid data acquisition and provides useful information for reconstructing surface of the Earth. However, Extracting information from LiDAR data is not easy task because LiDAR data consist of irregularly distributed point clouds of 3D coordinates and lack of semantic and visual information. This thesis proposed methods for automatic extraction of buildings and 3D detail modeling using airborne LiDAR data. As for preprocessing, noise and unnecessary data were removed by iterative surface fitting and then classification of ground and non-ground data was performed by analyzing histogram. Footprints of the buildings were extracted by tracing points on the building boundaries. The refined footprints were obtained by regularization based on the building hypothesis. The accuracy of building footprints were evaluated by comparing with 1:1,000 digital vector maps. The horizontal RMSE was 0.56m for test areas. Finally, a method of 3D modeling of roof superstructure was developed. Statistical and geometric information of the LiDAR data on building roof were analyzed to segment data and to determine roof shape. The superstructures on the roof were modeled by 3D analytical functions that were derived by least square method. The accuracy of the 3D modeling was estimated using simulation data. The RMSEs were 0.91m, 1.43m, 1.85m and 1.97m for flat, sloped, arch and dome shapes, respectively. The methods developed in study show that the automation of 3D building modeling process was effectively performed.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.2
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• pp.43-50
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• 2018

Biometric information computing is greatly influencing both a computing system and Big-data system based on the bio-information system that combines bio-signal sensors and bio-information processing. Unlike conventional data formats such as text, images, and videos, biometric information is represented by text-based values that give meaning to a bio-signal, important event moments are stored in an image format, a complex data format such as a video format is constructed for data prediction and analysis through time series analysis. Such a complex data structure may be separately requested by text, image, video format depending on characteristics of data required by individual biometric information application services, or may request complex data formats simultaneously depending on the situation. Since previous bio-information processing computing systems depend on conventional computing component, computing structure, and data processing method, they have many inefficiencies in terms of data processing performance, transmission capability, storage efficiency, and system safety. In this study, we propose an improved biosensing converged big data computing architecture to build a platform that supports biometric information processing computing effectively. The proposed architecture effectively supports data storage and transmission efficiency, computing performance, and system stability. And, it can lay the foundation for system implementation and biometric information service optimization optimized for future biometric information computing.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.1
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• pp.47-52
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• 2021

Recently, the share of wind power in energy markets has sharply increased with the active development of renewable energy internationally. In particular, large-scale wind farms are being developed far from the coast to make use of abundant wind resources and to reduce noise pollution. In addition to the electromagnetic interference (EMI) caused by offshore wind farms to coastal or air surveillance radars, it is necessary to investigate the EMI on global maritime distress and safety system (GMDSS) communications between ship and coastal stations. For this purpose, this study investigates whether the transmitted field of MF/HF band from a ship would be subject to interference or attenuation below the threshold at a coastal receiver. First, using geographic information system digital maps and 3D CAD models of wind turbines, the area of interest is electromagnetically modeled with patch models. Although high frequency analysis methods like Physical Optics are appropriate to analyze wide areas compared to its wavelength, the high frequency analysis method is first verified with an accurate low frequency analysis method by simplifying the surrounding area and turbines. As a result, the received wave power is almost the same regardless of whether the wind farms are located between ships and coastal stations. From this result, although wind turbines are large structures, the size is only a few wavelengths, so it does not interfere with the electric field of MF/HF distress communications.

• Journal of the Korean Geographical Society
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• v.38 no.4
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• pp.630-639
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• 2003

This study aims to analysis the distribution and change of cropland and forest, the Onseong, Saebyeol, and Eundeok counties on the lower reach of Duman(Tumen) river, northeast Korea, using 1992 year Landsat TM data, 2000 year Landsat ETM data, and digital terrain elevation data(DTED). Land cover and land use of the study areas are classified into cropland, forest, village, and water body, using the supervised classification method including 1:50,000 DTED analysis, image band composition, and principal component analysis(PCA). Results of quantitative analysis present that each growth rate of cropland of Onseong and Eundeok are 22.8% and 14.7% corresponding to decreasing rates of forest, 8% and 13.6% during 8 years from 1992 to 2000. In Onseong, Saebyeol, and Eundeok, each values of mean elevations and slope gradients increased to 192m, 95m, and 91m from 157m, 85m, and 78m, and to 6.6$^{\circ}$, 3.0$^{\circ}$, and 4.4$^{\circ}$ from 5.2$^{\circ}$, 2.5$^{\circ}$, and 3.0$^{\circ}$. Especially, in case of newly developed cropland, the values of mean elevation and mean gradient have 225m, 122m, and 127m, and 9.4$^{\circ}$, 5.1$^{\circ}$, and 8.0$^{\circ}$, in above three regions. These new croplands were developing along to deeper valleys and toward lower hill and mountain slope up to knickpoint zone of gradient change. Deforested lands for cropland have formed irregular pattern of patch-type, and become sources for the sheet erosion, rilling and gulleying in mountain slope and sedimentation in local river channel. Though there were no field checking, analysis using landsat images and GIS mapping can help understand actual environmental problems relating to cropland development of mountain slope in North Korea.