• Title/Summary/Keyword: Digital Disease

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Medical Digital Twin-Based Dynamic Virtual Body Capture System (메디컬 디지털 트윈 기반 동적 가상 인체 획득 시스템)

  • Kim, Daehwan;Kim, Yongwan;Lee, Kisuk
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.10
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    • pp.1398-1401
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    • 2020
  • We present the concept of a Medical Digital Twin (MDT) that can predict and analyze medical diseases using computer simulations and introduce a dynamic virtual body capture system to create it. The MDT is a technology that creates a 3D digital virtual human body by reflecting individual medical and biometric information. The virtual human body is composed of a static virtual human body that reflects an individual's internal and external information and a dynamic virtual human body that reflects his motion. Especially we describe an early version of the dynamic virtual body capture system that enables continuous simulation of musculoskeletal diseases.

Effect of digital therapies on balance and gait in children with cerebral palsy: A systematic review (디지털 치료제가 뇌성마비 아동의 균형 및 보행에 미치는 효과: 체계적 고찰)

  • Jung-Hyun Kim
    • Journal of Korean Physical Therapy Science
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    • v.30 no.4
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    • pp.92-110
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    • 2023
  • Background: Digital therapeutics are software medical devices that provide evidence-based treatments to prevent, manage, and treat disease. Digital therapies have recently been shown to be effective in motivating children with cerebral palsy as a tool in neuropsychological therapy. Digital therapies improve postural control, balance and gait in children with cerebral palsy. Therefore, this study aims to investigate the effects of digital therapies on balance and gait in children with cerebral palsy and to provide guidelines for prescribing digital therapies for children with cerebral palsy. Design: A Systematic Review Methods: This study searched for English-language articles published in medical journals from January 2000 to July 2023 using PubMed and MEDLINE based on the year of initiation of the digital therapy. The search terms used in the study were 'digital technology' OR 'digital therapeutic' OR 'mobile application' OR 'mobile health' OR 'virtual reality' OR 'game' AND 'cerebral palsy', 'balance' 'gait' as the main keywords. The final article was assigned an evidence level and a Physiotherapy Evidence Database (PEDro) score to assess the quality of clinical trials studies. Results: The digital therapies applied to improve balance and gait in children with cerebral palsy are game-based virtual reality training and the Nintendo Wii Fit program. Both digital therapy interventions had a significant effect on improving balance in children with cerebral palsy, and virtual reality training significantly improved balance and gait. However, there were no significant improvements in balance and gait within two weeks of treatment, regardless of the type of digital intervention. Conclusion: The study suggests that this data will be important in building the evidence base for the effectiveness of digital therapies on balance and gait in children with cerebral palsy and in advancing clinical protocols.

Chronic Disease Management using Smart Mobile Device (스마트 모바일 기기를 이용한 만성질환 관리)

  • Kim, Gui-Jung;Han, Jung-Soo
    • Journal of Digital Convergence
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    • v.12 no.4
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    • pp.335-342
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    • 2014
  • According to the recent trends in the growing elderly population, the chronically ill have increased. Thus the importance of the health care issues for them has emerged. In this paper, we want to implement a chronic disease management system using smart mobile devices. Proposed chronic disease management system is consisted of the biometric sensor, smart mobile devices, the patient management server, patient management DB, and patient symptoms analysis agent. The biometric sensor detects a biological information. Smart mobile devices receive the patient information from the sensor and transmit the information to the patient management server. The patient management server, patient management DB, and patient symptoms agent analysis agent analyze to process data delivered through a wireless communication network. Bio-signals includes modules of ECG, blood pressure, blood sugar and PPG. We are able to determine the current health status by monitoring measured biometric data through chronically ill health management system. We will focus on the individual service to be appropriate for a patient group in a mobile environment.

Design of Life Habits Disease System using Neural Network (신경망을 이용한 생활습관성 질환 시스템 설계)

  • Lee, Young-Ho;Chung, Kyung-Yong;Kang, Un-Gu
    • Journal of Digital Convergence
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    • v.10 no.6
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    • pp.1-6
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    • 2012
  • In modern society, the amount of information has been significantly increased according to the development of IT convergence technology. That leads to develop information obtaining and searching technologies from lots of data. However, they don't seem to have been actually effective for users' health care and promotion not only for limitations of Web-based information and but for lack of personalization. Health information support services have been generally developed in a format of inputting data on bio-information acquired into the computer for the existing network-based transmission. In this paper, a life habits disease system that uses the existing medical data and Framingham risk factor(FRS) performs neural network is proposed. Based on the proposed system, it is possible to provide the fundamental data and guideline to doctors for recognizing the life habits disease diagnosis of patients and that represents increases in the welfare of patients.

Raynaud Phenomenon due to Buerger’s Disease: A Case Report (버거씨병으로 인한 레이노이드 현상 환자 치험 1례)

  • Lee, Hyun-joong;Lee, Bo-yun;Lee, Young-eun;Yang, Seung-bo;Cho, Seung-yeon;Park, Jung-mi;Ko, Chang-nam;Park, Seong-uk
    • The Journal of Internal Korean Medicine
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    • v.36 no.3
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    • pp.427-435
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    • 2015
  • Here we report a case of a patient with Raynaud phenomenon due to Buerger’s disease to present the curative effects of herbal medicine in Buerger’s disease. The patient presented with pain, redness, and cyanosis of hands and feet. We used Korean medicine treatment modalities including acupuncture, moxibustion, and herbal medicines. We observed changes in symptoms through digital infrared thermographic imaging, taking photos of both hands and feet. After treatment, the symptoms of pain, redness, and cyanosis of both hands and feet were decreased and digital infrared thermographic imaging proved a rise in temperature of fingers and toes.

Comparison in nursing needs of heart disease patients depending on whether or not readmitted (재입원 여부에 따른 심질환자의 간호요구 비교)

  • Choi, Young-Sil
    • Journal of Digital Convergence
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    • v.12 no.6
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    • pp.519-526
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    • 2014
  • The purpose of this study was investigate nursing needs of heart disease patients depending on whether or not readmitted. Who had diagnosed heart disease and admitted on a general hospital was collected as a self-administered questionnaire method from March to June 2012. Collected data were analyzed through the SPSS 18.0 program. The average of total nursing needs is $4.12{\pm}.49$ point in patient who were not in readmission, and $3.89{\pm}.63$ point in patient joined readmission, there were significant differenced(p=.046). Therapeutic nursing needs are higher than others in nursing needs, in the both groups. Each rank and sub-regions is also different nursing needs according to readmission in two group. Physical, Social-emotional, educational and therapeutic nursing needs was correlated each other in depth. Therefore, focusing on patient's nursing needs according to patient's characteristics are required to perform nursing.

PRaDA : Web-based analyzer for Pathway Relation and Disease Associated SNP (웹 기반 단일염기다형성 연관 패스웨이 분석 도구)

  • Yu, Kijin;Park, Soo Ho;Ryu, Keun Ho
    • Journal of Digital Contents Society
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    • v.19 no.9
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    • pp.1795-1801
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    • 2018
  • Genome-Wide Association Study (GWAS) have been used to identify susceptibility genes for complex human diseases and many recent studies succeed to report common genetic factors for various diseases. Unfortunately, it is hard to understand all biological functions and mechanisms around the complex disease with GWAS only although the number of known associated genes with diseases is increased drastically because GWAS is a single locus based approach while not a gene but numerous factors may affect a disease associated pathways. PRaDA generates a combined report with genes, pathways and Gene Ontology (GO) using single nucleotide polymorphism (SNP) analysis output. The PRaDA reports not only directly associated pathways but also functionally related ones for identifying accumulated effects of low p-value SNPs. Through integrated information including indirect functional effects, user could have insights of overall disease mechanisms and markers.

Analysis of research trends on mobile health intervention for Korean patients with chronic disease using text mining (텍스트마이닝을 이용한 국내 만성질환자 대상 모바일 헬스 중재연구 동향 분석)

  • Son, Youn-Jung;Lee, Soo-Kyoung
    • Journal of Digital Convergence
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    • v.17 no.4
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    • pp.211-217
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    • 2019
  • As the widespread use of mobile health intervention among Korean patients with chronic disease, it is needed to identify research trends in mobile health intervention on chronic care using text mining technique. This secondary data analysis was conducted to investigate characteristics and main research topics in intervention studies from 2005 to 2018 with a total of 20 peer reviewed articles. Microsoft Excel and Text Analyzer were used for data analysis. Mobile health interventions were mainly applied to hypertension, diabetes, stroke, and coronary artery disease. The most common type of intervention was to develop mobile application. Lately, 'feasibility', 'mobile health', and 'outcome measure' were frequently presented. Future larger studies are needed to identify the relationships among key terms and the effectiveness of mobile health intervention using social network analysis.

Diagnostic Usefulness of Digital Infrared Thermal Image in Carpal Tunnel Syndrome (수근관 증후군에서 적외선 체열 검사의 진단적 유용성)

  • Park, Jihyun;Lee, Jang Woo;Lee, Sang Eok;Kim, Byung Hee;Park, Dougho
    • Clinical Pain
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    • v.18 no.2
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    • pp.70-75
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    • 2019
  • Objective: The purpose of this study is to evaluate the usefulness of infrared thermography in patients with carpal tunnel syndrome by comparing with electrodiagnostic and ultrasonographic findings. Method: From January 2014 to October 2017, electrodiagnosis, ultrasound, and digital infrared thermal image (DITI) of unilateral carpal tunnel syndrome diagnosed in a single hospital were retrospectively analyzed. The subjects with bilateral symptoms of carpal tunnel syndrome, peripheral vascular disease, diabetes, thyroid disease, fibromyalgia, rheumatic disease, systemic infection, inflammation, malignant tumor, and other musculoskeletal disorders such as finger osteoarthritis, peripheral neuropathy, cervical radiculopathy, and the previous history of surgery were excluded. Results: Of 53 patients diagnosed with carpal tunnel syndrome, 11 were male and 42 were female. The visual analogue scale was 4.9 ± 1.9, and the duration of symptom was 11.8 ± 12.5 months. There was no statistically significant difference in the body surface temperature between the unaffected and affected sides. The severity of symptoms, electrodiagnostic findings, and cross-sectional area of the median nerve significantly correlates to each other. The temperature difference between the second fingers of the affected and unaffected sides showed a weak correlation with the amplitude of sensory nerve action potential and onset latency of compound muscle action potential, when there was no significant correlation with the other parameters. Conclusion: The difference in temperature on the surface of the body, which can be confirmed by DITI, is little diagnostic value when DITI is performed in unilateral carpal tunnel syndrome patients, especially when compared with ultrasonography.

Machine Vision Platform for High-Precision Detection of Disease VOC Biomarkers Using Colorimetric MOF-Based Gas Sensor Array (비색 MOF 가스센서 어레이 기반 고정밀 질환 VOCs 바이오마커 검출을 위한 머신비전 플랫폼)

  • Junyeong Lee;Seungyun Oh;Dongmin Kim;Young Wung Kim;Jungseok Heo;Dae-Sik Lee
    • Journal of Sensor Science and Technology
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    • v.33 no.2
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    • pp.112-116
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    • 2024
  • Gas-sensor technology for volatile organic compounds (VOC) biomarker detection offers significant advantages for noninvasive diagnostics, including rapid response time and low operational costs, exhibiting promising potential for disease diagnosis. Colorimetric gas sensors, which enable intuitive analysis of gas concentrations through changes in color, present additional benefits for the development of personal diagnostic kits. However, the traditional method of visually monitoring these sensors can limit quantitative analysis and consistency in detection threshold evaluation, potentially affecting diagnostic accuracy. To address this, we developed a machine vision platform based on metal-organic framework (MOF) for colorimetric gas sensor arrays, designed to accurately detect disease-related VOC biomarkers. This platform integrates a CMOS camera module, gas chamber, and colorimetric MOF sensor jig to quantitatively assess color changes. A specialized machine vision algorithm accurately identifies the color-change Region of Interest (ROI) from the captured images and monitors the color trends. Performance evaluation was conducted through experiments using a platform with four types of low-concentration standard gases. A limit-of-detection (LoD) at 100 ppb level was observed. This approach significantly enhances the potential for non-invasive and accurate disease diagnosis by detecting low-concentration VOC biomarkers and offers a novel diagnostic tool.