• Title/Summary/Keyword: Digital Disease

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Design of Fetal Health Classification Model for Hospital Operation Management (효율적인 병원보건관리를 위한 태아건강분류 모델)

  • Chun, Je-Ran
    • Journal of Digital Convergence
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    • v.19 no.5
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    • pp.263-268
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    • 2021
  • The purpose of this study was to propose a model which is suitable for the actual delivery system by designing a fetal delivery hospital operation management and fetal health classification model. The number of deaths during childbirth is similar to the number of maternal mortality rate of 295,000 as of 2017. Among those numbers, 94% of deaths are preventable in most cases. Therefore, in this paper, we proposed a model that predicts the health condition of the fetus using data like heart rate of fetuses, fetal movements, uterine contractions, etc. that are extracted from the Cardiotocograms(CTG) test using a random forest. If the redundancy of the data is unbalanced, This proposed model guarantees a stable management of the fetal delivery health management system. To secure the accuracy of the fetal delivery health management system, we remove the outlier which embedded in the system, by setting thresholds for the upper and lower standard deviations. In addition, as the proportion of the sequence class uses the health status of fetus, a small number of classes were replicated by data-resampling to balance the classes. We had the 4~5% improvement and as the result we reached the accuracy of 97.75%. It is expected that the developed model will contribute to prevent death and effective fetal health management, also disease prevention by predicting and managing the fetus'deaths and diseases accurately in advance.

An Integrated Review on Main Caregiver's Burden of Elderly in Korean Nursing Home (한국 요양시설 노인의 주 돌봄자 부담감에 대한 통합적 고찰)

  • Kim, Eun Jeong;Sung, Kyung Mi
    • Journal of Digital Convergence
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    • v.17 no.6
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    • pp.267-277
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    • 2019
  • The purpose of this study is to investigate the burden of caring for the care-givers of the elderly in Korea by using an integrated literature review method. A total of 23 studies were analyzed using a search database. When care-givers had higher sense of filial and guilt or more than two diseases, they showed high level of feeling of burden. Also, they had high level of feeling of physical burden by their oldness, service period (especially at the period of 1-3 years). In the feeling of economic burden, they had high level of feeling of burden by their oldness, or elderly's disease periods. The feeling of burden by psychological condition was found in elderly in aged and the beginning of admission of nursing home. The feeling of burden by environment situation was found when the functional status of the elderly was bad. Therefore, we need to concern care-givers's feeling of burden with elderly people in the nursing home. In the future, I believe that the findings of this study will be helpful for development of the intervention program for alleviate burden for the care-giver.

Inhibitory Effects of Ethanol Extract of Rhodiola Sacra on Endoplasmic Reticulum Stress in Neuro-2A Cells (설치류 Neuro-2A 신경세포에서 홍경천 에탄올 추출물의 소포체 스트레스 억제효과)

  • Jo, Nam-Eun;Song, Young-soon
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.265-270
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    • 2019
  • Growing evidence suggests that mediating apoptotic cell death of ER stress plays an important role in pathological development of neurodegenerative diseases including Alzheimer's disease. The ethanol extract of Rodiola sacra (ERS) investigates whether ER stress protects neuroinvasive neuro-2A cells from homocysteine (Hcy) cell death and ER stress. In neuronal cells, Hcy markedly decreased the viability of the cells and induced the death of Annexin V-positive cells as confirmed by MTT assay. The Hcy cell viability and apoptotic loss pretreated with ERS were attenuated, and Hcy showed stress in the expression of C / EBP homologous protein, 78-kDa glucose regulatory protein and the junction of X-box binding protein-1 (xbp1) mRNA. ESR decreased Hcy-induced mRNA binding, GRP78 and CHOP cells induced Hcy-induced ER stress and apoptosis, and Western blotting revealed expression of heme oxygenase-1 and HO-1 enzyme activity Inhibition is indicative of therapeutic value for neurodegenerative diseases such as decreased cell death by hemin.

The role of Fatty acid binding protein 5 (Fabp5) in fatty acid partitioning in the liver (간에서 지방산 분할에 대한 지방산결합 단백질 5의 역할)

  • Park, Jae-Seung
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.283-291
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    • 2019
  • The aim of investigated the role of FABP5 in the hepatic lipogenesis and lipid metabolisms. Mice were overexpressed and silenced liver FABP5 using virus particles. Mice were fed a Western-type diet or regular chow for 1week and then sacrificed mouse after 24hr fasted. Liver homogenates were used for protein analysis by Western blot and mRNA levels by RT-PCR. Hepatic and serum lipids were analysed by thin-layer chromatography. Mice fed a Western-type or high saturated fat diet revealed large increases in FABP5 expression. However, FABP5 mRNA levels were drastically reduced under fasted. Hepatic TG was significantly increased FABP5-OEAV mice, but a significantly decreased hepatic free cholesterol under fed. The discovered a substantial decrease in hepatic TG mass with FABP5 silencing. In these data, presented evidence for an important role of FABP5 in hepatic lipogenesis and hepatic TG storage. FABP5 may also be a potential target in the treatment of NAFLD, metabolic syndrome, and obesity. Furthermore, studies to which transcription factors are involved in FABP5 expression and regulation.

Development of T2DM Prediction Model Using RNN (RNN을 이용한 제2형 당뇨병 예측모델 개발)

  • Jang, Jin-Su;Lee, Min-Jun;Lee, Tae-Ro
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.249-255
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    • 2019
  • Type 2 diabetes mellitus(T2DM) is included in metabolic disorders characterized by hyperglycemia, which causes many complications, and requires long-term treatment resulting in massive medical expenses each year. There have been many studies to solve this problem, but the existing studies have not been accurate by learning and predicting the data at specific time point. Thus, this study proposed a model using RNN to increase the accuracy of prediction of T2DM. This work propose a T2DM prediction model based on Korean Genome and Epidemiology study(Ansan, Anseong Korea). We trained all of the data over time to create prediction model of diabetes. To verify the results of the prediction model, we compared the accuracy with the existing machine learning methods, LR, k-NN, and SVM. Proposed prediction model accuracy was 0.92 and the AUC was 0.92, which were higher than the other. Therefore predicting the onset of T2DM by using the proposed diabetes prediction model in this study, it could lead to healthier lifestyle and hyperglycemic control resulting in lower risk of diabetes by alerted diabetes occurrence.

Characteristics and Effects of Lifestyle Interventions for Community Dwelling Older Adults: A Systematic Review (지역사회 노인을 대상으로 적용한 라이프스타일 중재의 형태와 효과에 관한 체계적 고찰)

  • Won, Kyung-A;Shin, Yun Chan;Park, Sangmi;Han, Areum;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.8 no.2
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    • pp.7-30
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    • 2019
  • Objective : The purpose of this study was to analyze the format and effects of lifestyle intervention provided to community dwelling older adults. This systematic review was written following the PRISMA guideline. Methods : The National Digital Science Library(NDSL), RISS, PubMed, and CINAHL were used to search for articles published from January 2008 to December 2017. In total, 20 articles were selected for the analysis and the risk of bias was screened through the Physiotherapy Evidence Database Scale. Lifestyle interventions in the articles were classified according to the disease of the participants. Results : Major contents of the lifestyle interventions were increased physical activity like moderately intensive exercise and education or training to help participants have a healthy diet. Of the 20 articles, 17 included more than 2 types of contents. Examining biochemical factors was the most common measurement among the multifaceted measurements used to assess the effects of lifestyle interventions. The results of the lifestyle interventions described in each article did not indicate congruent effects. 14 of the 20 articles reported the lifestyle interventions had significant effects. Conclusions : The results of this study could help practitioners select the contents of and provide lifestyle interventions to older adults. Further study on the various applications of lifestyle interventions in a community setting is necessary.

Recognition and use of health information for preliminary elderly and elderly people (예비고령층과 고령층의 건강정보 경로별 인식과 활용)

  • Jung, Woo Sik;Kang, Hyung Gon;Han, Semi;Kim, Eunhye
    • Journal of Digital Convergence
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    • v.19 no.6
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    • pp.419-427
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    • 2021
  • The purpose of this study is to identify the recognition and utilization of health information by acquisition channels for preliminary and elderly people. For the survey data of 200 people aged 55 to 64 and 200 seniors aged 65 or older, the chi-square test and Fisher's precision test were performed using MINITAB17. Although the two age groups were similar in obtaining health information through health professionals, preliminary elderly were more likely to obtain health information through mass media and Internet sites. In particular, the collection of health information through internet sites was more than four times higher than that of the elderly. While the preliminary people focused on searching the information on the health care and prevention, older people explored comprehensive information on health, including disease prevention and treatment, through each channel. Both groups showed positive recognition about the acquired health information. The results of this study confirmed that all channels, including internet sites, can be usefully used in the delivery of health-related information to the elderly in the future. In addition, it is suggested to consider age characteristics and health information utilized by each channel in the development of various contents for the improvement of self-health management of the elderly.

Factors Influencing in the Infection Control Performance of COVID-19 in Nurses (간호사의 COVID-19에 대한 감염관리 수행도에 영향을 미치는 요인)

  • Lee, Mi-Hyang;Kim, Min Young;Go, Young Jin;Kim, Doo Ree;Lim, Hyo Nam;Lee, Kyung Hwa;Yang, Sun-Yi
    • Journal of Digital Convergence
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    • v.19 no.3
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    • pp.253-261
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    • 2021
  • This study was conducted to investigate the factors influencing in the infection control performance of coronavirus infection disease-19 in registered nurse. Data were collected using descriptive structured questionnaires to examine the factors of influencing in the infection control performance. General characteristics, knowledge of infection control, anxiety, fatigue, and coronavirus infection-19 (COVID-19) respiratory infection management performance were identified from structured questionnaire. Data were analyzed using independent t-test, ANOVA, correlation analysis, and multiple regression analysis were performed using the IBM SPSS 21.0 program. Anxiety and respiratory infection management performance was a negative correlation. Multiple regression analysis indicated anxiety was predicted component of performance of coronavirus infection-19 respiratory infection management. The results indicate a need to decrease degree of anxiety by developing educational programs to improve nurses' ability to manage coronavirus infection-19 respiratory infections. In addition, it is necessary to consider applying a role-play or simulation education method so that registered nurse can take care of patients with emerging infectious diseases in advance.

Interregional Variant Factor Analysis of Hypertension Treatment Rate in COVID-19 (코로나19에서 고혈압 치료율의 지역 간 변이요인 분석)

  • Park, Jong-Ho;Kim, Ji-Hye
    • Journal of Digital Convergence
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    • v.20 no.4
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    • pp.469-482
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    • 2022
  • The purpose of this study is to analyze regional variation factors of hypertension treatment rate in COVID-19 based on the analysis results based on ecological methodology. To this end, data suitable for ecological analysis were collected from the Korea Centers for Disease Control and Prevention's regional health statistics, local government COVID-19 confirmed cases, National Health Insurance Corporation, Health Insurance Review and Assessment Service's welfare statistics, and Korea Transport Institute's traffic access index. Descriptive statistics and correlation analysis were conducted using SPSS Statistics 23 for regional variation and related factors in hypertension treatment rate, and geographical weighted regression analysis was conducted using Arc GIS for regional variation factors. As a result of the study, the overall explanatory power of the calculated geo-weighted regression model was 27.6%, distributed from 23.1% to 33.4% by region. As factors affecting the treatment rate of hypertension, the higher the rate of basic living security medical benefits, diabetes treatment rate, and health institutions per 100,000 population, the higher the rate of hypertension treatment, the lower the number of COVID-19 confirmed patients, the lower the rate of physical activity, and the alcohol consumption. Percentage of alcohol consumption decreased due to COVID-19 pandemic. It was analyzed that the lower the ratio, the higher the treatment rate for hypertension. Based on these results, the analysis of regional variables in the treatment rate of hypertension in COVID-19 can be expected to be effective in managing the treatment rate of hypertension, and furthermore, it is expected to be used to establish community-centered health promotion policies.

Management and Knowledge for the Prevention of Infectious Diseases in the elderly (노인의 감염병 예방을 위한 관리 및 지식도)

  • Kang, Kyung-hee;Kim, Kwang Hwan;Kim, Young-Ha
    • Journal of Digital Convergence
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    • v.20 no.5
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    • pp.713-720
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    • 2022
  • The objective of this study is to provide the basic data for the development of educational programs for the prevention of infectious diseases targeting the elderly by researching the degree of personal hygiene practice, perceived risk of infection, and knowledge and importance of infectious diseases for the prevention of infectious diseases of the elderly. Using the structured questionnaire for a month of October in 2021, this study surveyed total 110 elderly people in their 65 or up by using the one-to-one individual interview method through the Gallup Korea. The collected data was analyzed by using the IBM SPSS Statistics 25.0 Program. In the results of analyzing the ranking by converting it into Borich's needs formula and then totaling up the degree of importance and knowledge, it was researched as the 1st place for the transmission path of infectious diseases, the 2nd place for the preventive method of infectious diseases, the 3rd place for the treatment method of infectious diseases, the 4th place for the handling procedure in case an infectious disease was doubted and confirmed, and the 5th place for the major symptoms of infectious diseases. The results of this study could contribute to the improvement of infection preventive practice through the provision of proper information to subjects, by providing the basic data for the development of educational programs for the elderly reflecting the needs of prevention and management of infectious diseases.