• Title/Summary/Keyword: Digital Disease

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The Expression changes of AMPK, ERK-1/2, and p38 protein associated with Exercise in the Mouse hippocampus exposed to Radiofrequency Radiation (전자파(電磁波)에 노출된 생쥐의 해마에서 운동이 AMPK, ERK-1/2, p38 단백 발현 변화에 미치는 생체 영향)

  • Lee, Min-Sun;Park, Oak Jin;Kim, Hyun Taeg;Kim, Myeung Ju
    • Journal of Digital Convergence
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    • v.18 no.3
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    • pp.267-273
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    • 2020
  • To determine the biological effects of exercise on hippocampus in mice brain exposed to radiofrequency radiaton (RF), the expression of AMPKα, p-AMPKα, ERK1/2, p-ERK1/2, p38, and p-p38 protein in the mouse exposed to RF were investigated in the hippocampal tissues, Western blot method was used to compare the protein expression levels for each molecule. Significant increases in protein expression of individual and phosphorylated molecules were observed in the spontaneous exercise group, and the expression of these molecules was notably decreased in the RF exposure and spontaneous exercise group. This study shows that neuroplasticity can be increased by exercise in hippocampus that is responsible for memory, but memory and cognitive function may be affected by exposure to RF. We may expect clinically interesting results on dementia or Alzheimer disease if we proceed further investigation on the effect of RF.

A clinical study on patients with Cold Hypersensitivity on hands and feet and their autonomic nervous system function using of Heart Rate Variability(HRV) (수족냉증 환자의 실태 및 HRV(Heart Rate Variability)를 이용한 자율신경계 기능 평가 연구)

  • Kim, Eun-Sook;Hwang, Jae-Ho;Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub;Choi, Jae-Ho
    • Journal of Oriental Medical Thermology
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    • v.5 no.1
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    • pp.1-13
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    • 2006
  • Objectives : This study was designed to analyze basic data for cold hypersensitivity patients with a questionnaire and investigate correlation between cold hypersensitivity and Heart Rate Variability(HRV). Methods : 49 patients who complain of cold hypersensitivity on hands and feet in ambulatory care were investigated in Oriental Gynecology, Kyunghee Oriental Medical Center and Women medical center, Kangnam Koreana hospital from May 1, 2006 to October 20, 2006. All patients were asked to answer a questionnaire. After careful I examination to rule out other disease which may affect Digital Infrared Thermal Imaging(DITI) and HRV data, patients were taken thermography for the diagnosis of cold hypersensitivity Based on the result of thermography, the patients were divided into two groups(Objective cold hypersensitivity and Subjective cold hypersensitivity). Then, these two groups were compared using HRV data which was measured in the supine position for 5 minutes. Results: 1. For most patients, cold hypersensitivity first developed during puberty. 2. The parts of the body that felt cold first time were hands and feet. 3. The cold sensation was increased in winter or at bedtime Showing that the sensation can be changed according to the level of coldness. 4. Among women who sufferfrom cold hypersensitivity, very few of them were treated. 5. More than half of cold hypersensitivity patients's family member also had a cold hypersensitivity. 6. The decrease in mean values of LF/HF ratio was observed in objective cold hypersensitivity group than subjective cold hypersensitivity group and the decrease was significant(P=0.014) when examined by Student t-test. Conclusions : It is necessary that the cold hypersensitivity patients should be treated carefully considering the facts mentioned above. And it can be suggested that dysautinomia be related with cold hypersensitivity and be evaluated by HRV.

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Effect of Complex-exercise on Diabetes Outbreak Prediction Rate, Body Composition and Vascular Compliance in Obese smokers (비만흡연자의 복합운동이 당뇨발생예측률 및 신체조성, 혈관탄성에 미치는 영향)

  • Kim, Seung-Suk
    • Journal of Digital Convergence
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    • v.12 no.10
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    • pp.587-595
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    • 2014
  • This research aimed at analyzing the influence of complex-exercise on diabetes outbreak prediction rate, body composition and vascular compliance in obese smokers and suggesting effective exercise program for obese smokers' healthy life. The research object was composed of the 20 employees, obese smokers in their age of 40s, of T company, which is the subcontractor of H company in D Metropolitan City, who learned the purpose of this research enough and wrote the consent form of voluntary participation, who have no medical history and currently no special disease, as well as no experience in regular exercise. The researcher conducted an inspection on diabetes outbreak prediction rate and body composition, vascular compliance, also, implemented descriptive statistics to calculate the average and standard deviation before the test and after implementing 12 weeks' complex-exercise program, and verification on the difference between before after the test was analyzed by using Paired t-test. With statistical significance level p<.05, the research results are as follows. after participating in 12 weeks' complex-exercise program, diabetes outbreak prediction rate, weight, body fat percentage, skeletal muscle mass, abdominal fat rate and vascular compliance showed statistically meaningful level of change in upper extremities(right hand, left hand), nether extremities(right foot, left foot) p.<05.

Knowledge and Status of Oral Health according to Smoking in some College Students (일부 대학생들의 흡연에 따른 구강건강 실태와 지식)

  • Park, Il-Soon;Kim, Hye-Jin
    • Journal of Digital Convergence
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    • v.12 no.10
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    • pp.445-453
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    • 2014
  • The purpose of this study was to examine the necessity of oral health education to analyze the knowledge and status of oral health according to smoking in some college students. The subjects in this study were 217 selected college students, on whom a survey was conducted from September 3 to September 7, 2013. The data were analyzed using SPSS 19.0(SPSS 19.0 K for window, SPSS Inc USA). The findings of the study were as follows: First, concerning toothbrushing frequency, the smokers brushed their teeth twice, and the nonsmokers did that three times(p<0.05). The male students did toothbrushing twice, and the female students did that three times(p<0.05). As to scaling experience, the female students got their teeth cleaned more often(p<0.05). Second, the nonsmokers who had received oral health education outnumbered the smokers who had(p<0.01). In regard to the necessity of smoking-related oral health education, both of the smokers and the nonsmokers replied it was necessary(p<0.05). Third, as for the level of oral health knowledge, the nonsmokers were more aware than the smokers that the use of oral hygiene supplies had an effect on the prevention of dental caries(p<0.05). Given the findings of the study, the smoking-related oral health education and the development of programs that are intended for college students seems necessary.

A Study on the Medical Tourism and Activation : With focus on Medical Communication (의료관광의 활성화를 위한 제언: 의료커뮤니케이션을 중심으로)

  • Lee, Seung Jae
    • Journal of Digital Convergence
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    • v.12 no.3
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    • pp.391-397
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    • 2014
  • This paper is concerned with medical tourism, which is expected to become the new growth engine of the 21st century. Medical tourism is a collaborative and synergistic composition of Healthcare and Tourism, and has led to a remarkable growth in 2012 since the year 2009, exhibiting huge growth potential. This paper reviews the emerging market of the medical tourism with five major hospitals in Korea from the perspective of medical tourists, and makes suggestions for the global health care and the sustainable development in Korean medical tourism as a growth market: the construction of websites for active services and transparent management of medical expenses with proper arrangement of medical consulting and advices, cooperation of the health care center and the medical tourism industry, and the activation of healthcare communication. For the smooth progress of medical tourism, this paper suggests two separate communication channels: one for the patient tourists and the other for the medical tourism coordinators. The former needs accuracy with professional knowledge on the healthcare and communication, which should be classified as medical interpreters working with disease-oriented medical tourists. The latter refers to international medical coordinators dedicated to the smooth progress of medical tourism and services. This paper also points out the creative efforts to improve the relatively poor infrastructure of tourism industry to accommodate the medical tourists, and improve the medical tourism industry.

Developing data quality management algorithm for Hypertension Patients accompanied with Diabetes Mellitus By Data Mining (데이터 마이닝을 이용한 고혈압환자의 당뇨질환 동반에 관한 데이터 질 관리 알고리즘 개발)

  • Hwang, Kyu-Yeon;Lee, Eun-Sook;Kim, Go-Won;Hong, Sung-Ok;Park, Jong-Son;Kwak, Mi-Sook;Lee, Ye-Jin;Im, Chae-Hyuk;Park, Tae-Hyun;Park, Jong-Ho;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.14 no.7
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    • pp.309-319
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    • 2016
  • There is a need to develop a data quality management algorithm in order to improve the quality of health care data. In this study, we developed a data quality control algorithms associated diseases related to diabetes in patients with hypertension. To make a data quality algorithm, we extracted hypertension patients from 2011 and 2012 discharge damage survey data. As the result of developing Data quality management algorithm, significant factors in hypertension patients with diabetes are gender, age, Glomerular disorders in diabetes mellitus, Diabetic retinopathy, Diabetic polyneuropathy, Closed [percutaneous] [needle] biopsy of kidney. Depending on the decision tree results, we defined Outlier which was probability values associated with a patient having diabetes corporal with hypertension or more than 80%, or not more than 20%, and found six groups with extreme values for diabetes accompanying hypertension patients. Thus there is a need to check the actual data contained in the Outlier(extreme value) groups to improve the quality of the data.

Development of Advanced TB Case Classification Model Using NHI Claims Data (국민건강보험 청구자료 기반의 결핵환자 분류 고도화 모형 개발)

  • Park, Il-Su;Kim, Yoo-Mi;Choi, Youn-Hee;Kim, Sung-Soo;Kim, Eun-Ju;Won, Si-Yeon;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.11 no.9
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    • pp.289-299
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    • 2013
  • The aim of this study was to enhance the NHI claims data-based tuberculosis classification rule of KCDC(Korea centers for disease control & prevention) for an effective TB surveillance system. 8,118 cases, 10% samples of 81,199 TB cases from NHI claims data during 2009, were subject to the Medical Record Survey about whether they are real TB patients. The final study population was 7,132 cases whose medical records were surveyed. The decision tree model was evaluated as the most superior TB patients detection model. This model required the main independent variables of age, the number of anti-tuberculosis drugs, types of medical institution, tuberculosis tests, prescription days, types of TB. This model had sensitivity of 90.6%, PPV of 96.1%, and correct classification rate of 93.8%, which was better than KCDC's TB detection model with two or more NHI claims for TB and TB drugs(sensitivity of 82.6%, PPV of 95%, and correct classification rate of 80%).

Factors influencing the return of spontaneous circulation of patients with out-of-hospital cardiac arrest (병원외 심정지 환자의 자발적 순환 회복에 영향을 미치는 요인)

  • Park, Il-Su;Kim, Eun-Ju;Sohn, Hae-Sook;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.11 no.9
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    • pp.229-238
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    • 2013
  • Out-of-hospital cardiac arrest is a major public health problem in Korea. The survival rate to discharge remains at approximately 3.5% and only 1% have good neurological function. To increase the survival rate, prehospital care should restore spontaneous circulation. The purpose of this study was to analyze the factors associated with return of spontaneous circulation(ROSC) after out-of-hospital cardiac arrest. Data used for this study were collected from KCDC Out-of-Hospital Cardiac Arrest Surveillance 2009. As for the results of decision tree analysis, it is clear that prehospital CPR, cardiac arrest witness, activity, past history(cancer/heart disease/stroke), place, bystander CPR, response time, age, etc are significant contributing factors in ROSC. Among 16 cardiac arrest types from decision tree classification, the ROSC rate of type 1 is the highest(29.6%). Also notable is the fact that bystander CPR was strongly correlated with ROSC of patents with cardiac arrest occurring in non-public places. Community resources should be concentrated on increasing bystander CPR and early prehospital emergency care.

Aerobic Exercise's Influence on Obese Female College Students'Arterial Pulse Wave Velocity, Cardiorespiratory Systems and Body Composition (유산소 운동이 비만 여자대학생의 동맥맥파속도, 호흡순환계 및 신체조성에 미치는 영향)

  • Kim, Seung-Suk
    • Journal of Digital Convergence
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    • v.15 no.7
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    • pp.407-414
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    • 2017
  • In order to identify an Convergence aerobic exercise's influence on obese female college students' Cardiorespiratory systems and arterial pulse wave Velocity, this study targeted female college students in D University in Y-gu, D-City, and selected total 26 ones having body fat percentage over 30% with no special disease in past and at present and no regular physical activity. After finally confirming their participation in this experiment by completely explaining the purpose of and contents of this experiment and getting the subjects' written contents to participate in the experiment, the investigator randomly arranged the subjects into the exercise group(N=13) and the control group(N=13) and conducted a 12-week aerobic exercise program to the exercise group this study got the following conclusion. First, concerning the body composition's change, the exercise group showed significant reduction in the weight, the body fat percentage, and the abdominal fat percentage. Second, for the respiratory & cardiovascular systems'change, the exercise group showed significant increase in the maximal oxygen uptake, the maximal heart rate, and the maximal breathing capacity. Third, for the arterial pulse wave Velocity's change, the exercise group showed significant reduction in the upper body(right and left hands) and lower body (right and left feet).

Association between Sleep duration and Grip strength in Korean adults Using Convergence Survey Data (융복합조사자료를 활용한 수면시간과 악력 간 관련성 연구)

  • Jang, Sae-kyun;Kim, Jae-Hyun;Boo, Yoo-Kyung
    • Journal of Digital Convergence
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    • v.17 no.12
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    • pp.435-444
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    • 2019
  • The purpose of this study was to investigate the relationship between sleep duration and muscle strength in Korean adults aged 19 years and older. The cross-sectional analysis was conducted using the 2016 National Health and Nutrition Examination Survey data and Chi square test and multiple regression analysis were used. As a result of the analysis, the grip strength of those with more than weekday average sleep duration of 9 hours was found to be -1.267kg compared with those with weekday average sleep duration of 7 hours. The grip strength of those with more than weekend average sleep duration of 9 hours was found to be -0.879kg compared with those with weekend average sleep duration of 7 hours. In model simultaneously adjusting for both the average weekday and weekend average sleep duration, weekday average sleep duration of 9 hours was found to be -1.034kg compared with those with weekday average sleep duration of 7 hours. Therefore, careful observation will be required in light of the fact that both sleep duration and grip strength can predict future health conditions.