• 한국전산유체공학회:학술대회논문집
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• 2004.03a
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• pp.71-76
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• 2004

An extension of our recently developed locally linear reconstruction scheme to 2 dimensional incompressible flow solver is presented. The solver is based on a semi-implicit fractional step method in which the convective term is discretized by Adams-Bashforth method and the diffusion term by Crank-Nicolson method. Several numerical examples are tested to demonstrate the mesh type independent accuracy of the solver, which include decaying vortex flow, square cavity flow, and flow around a circular cylinder. The above examples are solved on quadrilateral or hybrid meshes. For all numerical examples, we obtained reasonable results.

• Water Engineering Research
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• v.3 no.4
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• pp.247-258
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• 2002

This paper presents a non-isotropic turbulence modeling of flows over bedforms. The Reynolds stress model is used for the turbulence closure. In the model, Launder, Reece, and Rodi's model and Hanjalic and Launder's model are employed f3r the pressure strain correlation term and the diffusion term, respectively. The mean flow and turbulence structures are simulated and compared with profiles measured in the experiments. The numerical solutions from two-equation turbulence models are also provided for comparisons. The Reynolds stress model yields the separation length of eddy similar to the other numerical results. Using the developed model, the resistance coefficients are also estimated for the flows at different Froude numbers. Karim's (1999) relationship is used to determine the bedform geometry. It is found that the values of the form drag and the skin friction are very similar to those obtained by the other turbulence models. meaning higher values of the form drag and lower values of the skin friction compared with the empirical formulas.

• Biomedical Science Letters
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• v.13 no.3
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• pp.175-182
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• 2007

In vitro ciprofloxacin (CFX)-release study and bioassay using microorganisms were performed to estimate the retention of the antimicrobial activity of the CFX-incorporated central venous catheters (CFX-CVCs). The release experiments were carried out under the optional CFX-release conditions to mimic the in vivo environment. The release of CFX experienced an initial burst followed by a slow and steady matrix-diffusion controlled release. The 1.0CP (polyurethane catheter containing 1.0% (w/w) of CFX) under dynamic condition showed a near zero-order CFX release profile, which is beneficial for the long-tenn antimicrobial activity. The modified Kirby-Bauer method was performed employing S. aureus and E. coli to evaluate the retention of antimicrobial activity of the catheters retrieved from the release experiments. The 1.0CP showed the long-term antimicrobial activity (${\geq}\;21$ days) against both S. aureus and E. coli. These results indicate that 1.0CP is useful as a long-tenn indwelling CVC.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.9
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• pp.2297-2307
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• 1995

An experimental study on the structure of a separated shear layer downstream of the backward-facing step has been performed by examining mean flow and turbulent quantities in terms of free stream turbulence. When free stream turbulence exists, the entrainment rate of the separated shear layer and the flow rate in the recirculation region are enhanced, resulting in shorter reattachment length. The production and diffusion terms in the turbulent kinetic energy balance are shown to increase more than the dissipation term does. Rapid decrease of the pressure-strain term in the shear stress balance implies the enhancement of the three-dimensional motion by free stream turbulence.

• Journal of Hydrogen and New Energy
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• v.16 no.4
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• pp.324-333
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• 2005

The kinetics of external hydrogen embrittlememt is considered. The equation of the crack growth rate (CGR) is derived from modification of the model developed by Wilkinson and Vitek. After calculation of hydrogen pressure build-up in the void, the effect of the internal hydrogen pressure on the void growth is added. The CGR is expressed by two terms. One is the term dependent on the critical stress, which is exactly same as Wilkinson and Vitek. The other is term dependent on the pressure of the hydrogen in void.

• 한국신재생에너지학회:학술대회논문집
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• 2006.06a
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• pp.63-66
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• 2006

A long term deactivation study was carried out with commercial MEA provided by Hyundai Motor Co. The deactivation phenomena were observed only at high voltage region where there is no diffusion-limited reaction. A rapid deactivation was observed up to 40h owing to the sintering of Pt particles. This was followed a gradual increase in the activity up to 300 h, which is probably caused by improvement in the electrode properties in the presence of current during the reaction. After 300 h, monotonic decrease in the activity was observed owing to dissolution of Pt particles especially in the cathode. The presence oxygen is the cause of oxidation and dissolution of Pt. The dissolution rate can be somewhat retarded by generation of current, which reduces Pt ion back to Pt in the cathode.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.4B
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• pp.620-629
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• 2010

The analogue radio broadcasting was proven to be a successful and efficient media of delivering information because of free content and wide availability of cheap receivers. But the competition was more dropped than any other media due to the limited amount of radio spectrum that is available. The risk of doing nothing is to miss the opportunity and to loss existing audiences in the long term, or to be locked into inefficient proprietary systems. That is the reason why it is important to act now. It is time for regulators and market participants to hone their strategies, by clearly establishing factors to adopt the digital radio and to facilitate its diffusion. The purpose of this study is to find adoption factors that affected to potential users of digital radio broadcasting. Former research based on diffusion of innovation theory showed that adoption of innovation is affected by demographic variables, media usage and consumer's attitude of innovation. In this study based on a consumer survey, we examined those factors and characteristics of each steps that suggested in diffusion of innovation theory. The findings of this study have implications to explore the suitable technologies and services of digital radio broadcasting.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.3
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• pp.136-142
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• 2019

Nuclear power plant concrete structures are in contact with the coast, and durability due to chloride attack is very important because it is used as cooling water by taking seawater. For this purpose, a 3-year long-term saltwater immersion test was carried out to evaluate chloride ion diffusion coefficient and age apponent (m) The m values of the foundation with 4,000 class was 0.35 ~ 0.39, similar to KCI or ACI suggested values. essential service water constructions and tunnels of 5,000 class were 0.44 ~ 0.53 and 6,000 class, and 0.62 of reactor containment buildings were similar to the proposed values of FIB. As a result of the prediction of the service life with the measured age coefficient, all the safety related concrete structures of the nuclear power plants satisfied the service life of more than 60 years.

• Journal of Korean Neurosurgical Society
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• v.66 no.5
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• pp.562-572
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• 2023

Objective : Bevacizumab is a feasible option for treating cerebral radiation necrosis (RN). We investigated the clinical outcome of RN after treatment with bevacizumab and factors related to the initial response and the sustained effect. Methods : Clinical data of 45 patients treated for symptomatic RN between September 2019 and February 2021 were retrospectively collected. Bevacizumab (7.5 mg/kg) was administered at 3-week intervals with a maximum four-cycle schedule. Changes in the lesions magnetic resonance image (MRI) scans were examined for the response evaluation. The subgroup analysis was performed based on the initial response and the long-term maintenance of the effect. Results : Of the 45 patients, 36 patients (80.0%) showed an initial response, and eight patients (17.8%) showed delayed worsening of the corresponding lesion. The non-responders showed a significantly higher incidence of diffusion restriction on MRI than the responders (100.0% vs. 25.0%, p<0.001). The delayed worsening group showed a significantly higher proportion of glioma pathology than the maintenance group (87.5% vs. 28.6%, p=0.005). Cumulative survival rates with sustained effect were significantly higher in the groups with non-glioma pathology (p=0.019) and the absence of diffusion restriction (p<0.001). Pathology of glioma and diffusion restriction in MRI were the independent risk factors for non-response or delayed worsening after initial response. Conclusion : The initial response of RN to bevacizumab was favorable, with improvement in four-fifths of the patients. However, a certain proportion of patients showed non-responsiveness or delayed exacerbations. Bevacizumab may be more effective in treating RN in patients with non-glioma pathology and without diffusion restriction in the MRI.

• Economic and Environmental Geology
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• v.53 no.1
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• pp.11-21
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• 2020

One-dimensional analytical solutions were used for forward and back diffusion of trichloroethylene (TCE) and tetrachloroethylene (PCE) in a single system with high- and low-permeability layers. Concentration profiles in a low-permeability layer, diffusive fluxes at the interface between the high- and low-permeability layers, and contaminant persistence in the high-permeability layer due to back diffusion were simulated with a comparison of semi-infinite and finite analytical solutions. In order to validate the analytical solutions used in this study, the results of one-dimensional analytical solutions developed by Yang et al. (2015) were compared with Nash-Sutcliffe model efficiency coefficient (NSE). When compared with Yang et al. (2015), the analytical solutions used in this study showed good agreements (NSE = 0.99). When compared with semi-infinite analytical solutions, TCE and PCE concentration profiles in the low-permeability layer, the diffusive fluxes, and the contaminant tailings of the high-permeability layer were underestimated. In order to determine the appropriate analytical solutions based on the effective diffusion coefficient, the thickness of the low-permeability layer, and the diffusion time in the TCE and PCE contaminated site, a term of dimensionless diffusion length (Z_d) was used. If the Z_d is less than 0.7, the semi-infinite solutions can be used to simulate accurate concentration profiles in low-permeability layers. If the Z_d is greater than 0.7, the reliability of simulations may be improved by using the finite solutions.