• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2923-2928
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• 2015

Background: Gallbladder carcinoma (GBC) has been stated as an Indian disease, with the highest number of cases being reported from certain districts of northeast India, which has an ethnically distinct population. Unfortunately there are no scientific reports on the underlying molecular mechanisms associated with the pathogenesis of the disease from this region. Aim: The present study evaluated the role of differential expression of human telomerase reverse transcriptase (hTERT) in the development of gall bladder anomalies. Materials and Methods: Blood and tissue samples were collected from patients undergoing routine surgical resection for clinically proven cases of gallbladder disease {cholelithiasis (CL, n=50), cholecystitis (CS, n=40) and GBC (n=30) along with adjacent histopathologically proved non-neoplastic controls (n=15)} with informed consent. Whole blood was also collected from age and sex matched healthy controls (n=25) for comparative analysis. Differential hTERT mRNA expression was evaluated by semi-quantitative rt-PCR and real-time PCR based analysis using ${\beta}$-actin as an internal control. Evaluation of differential hTERT protein expression was studied by Western blot analysis and immunoflourescence. Statistical analysis for differential expression and co-relation was performed by SPSSv13.0 software. Results: Gallbladder anomalies were mostly prevalent in females. The hTERT mRNA and protein expression increased gradiently from normal

• Journal of Satellite, Information and Communications
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• v.7 no.3
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• pp.30-34
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• 2012

National Meteorological Satellite Center(NMSC) of Korea Meteorological Administration(KMA) has launched to implement the application development to get prepared for the space weather operation since 2010. As a action of KMA's space weather work, NMSC constructed Global Navigation Satellite System(GNSS) application system for meteorology and space weather. We will introduce NMSC's space weather application system which derives regional TEC(Total Electron Content) in near real time using nation-wide GNSS network data. First, We constructed system for collecting GNSS data, which is currently collecting about 80 stations operated by agencies like NGII(National Geographic Information Institute), Central Office of DGPS(Differential GPS), and KASI(Korea Astronomy and Space Science) including KMA's own data of 2 stations. In order to retreive regional TEC over Korean peninsular, we build up the automatic processes running every 1-hour. In these processes, firstly, GNSS data of every stations with 24 hours time window are processed to derive DCBs(Differential Code Biases) of each GNSS station and TEC values on every ionosphere piercing point(IPP). Then we made gridded regional TEC map with resolution of 0.25 degree from 31N, 121E to 41N, 135E by combination of all station results within 30 minutes window with assumption that TEC of a given point during a given 30 minutes window would have a constant value. The grid points without TEC value are interpolated using Barnes objective analysis. We presentour regional TEC maps, which can describe better on the status of ionosphere over Korean peninsular compared to IGS TEC maps.

• Journal of the Korean association of regional geographers
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• v.22 no.1
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• pp.225-239
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• 2016

The Jeogchung Chogye Basin shows perfect basin formation surrounded with divides, excluding outlet where Sannae River combining various small rivers escapes the basin. High mountains distribute at southwestern, southern and southeastern divides of the basin consisting of hornfels, while hilly mountains are found at northern divide consisting of sedimentary rock. Alluvial fans and flood plains occupy bottom of the basin. While extensive alluvial fans are found at the front of southern divide where rivers with large drainage areas rise, alluvial fans toward eastern and western divides become small due to low elevation of divides. Flood deposits by Hwang River are attributed to development for most of flood plains at northern part of the basin. The basin seems to be developed not by differential erosion or meteorite impact, but by bedrock weathering along lineament or fault lines by ground motion.

• Journal of the Korean association of regional geographers
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• v.8 no.4
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• pp.468-479
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• 2002

This study attempts to characterize Taebaek mountainous region as a natural unit, relating to morphoclimatic milieu and landform development patterns of the mountains of each lithologic type. In the case of granitic mountains of Nothern parts of this region, the slopes presents more or less steep or irregular profile because of abundant microforms of exposed bedrocks and blocks. The development of such landscape is essentially due to differential weathering, associated with difference of joint density. In the case of gneissic mountains, the slopes are well regularized straight steep ones, due not only to generalized superficial weathering but also to massmovement of weathered materials. In the Middle parts of this region, especially in Taegwallyong area, with frequent alternations both of freezing-thawing and of snow accumulation-melting, the roles played by cryo-nival processes proved to be important in weathering of granite as well as in morpho-pedogenesis. In this area, weathered mantle, developed by cryogenic activity under humid condition of nival environment, covered almost all over the slopes. Although Southern parts of this region consist of limestone, on the mountainous volume, distribution of Karst forms are limited while predominate none karst forms such as cockpit type peaks, V-shaped type valleys dissecting steep slopes covered with thin deposits in thickness containing rock debris.

• The Korean Journal of Franchise Management
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• v.6 no.1
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• pp.21-41
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• 2015

The purpose of the study is to review the real situations of the income-gap between urban and rural areas which is focused on as one of the biggest issues revealed in the process of Chinese economic development and to find out which factors will alleviate or deteriorate such income-gap, also to find out such factors will effect differently on the regional characteristics. To analyze it, six factors such as industrialization-ratio, urbanization-ratio, tertiary industry-ratio, the level of both governmental educational support and agricultural support, and Chinese dual-economic structure are considered as explanatory variables, and OLS regression analysis was implemented to the factor data for the period of 1986-2007 about Chinese 31 districts(castles and cities). The results of the analysis show that both industrialization factors and urbanization factors affect significantly to alleviate income-gap between urban and rural areas, and as predicted, they also shows that dual-economic structure between urban and rural areas is the most biggest factors to enlarge the above mentioned income-gap. However, in accordance to the different level of economic development in eastern, central, and western districts the study shows that such factors will affect them differently respectively. The contents are as follows; In eastern district governmental educational support factor will affect the most great influence to alleviate the income-gap, in central district industrialization factor will affect the most great influence to alleviate the gap, and western district governmental agricultural support factor will affect the most great influence to alleviate the gap. Therefore, in solving the issue of income-gap between urban and rural areas in China we recommend that it is necessary for more differential policy in considering regional characteristics than unilateral policy to Chinese whole areas.

• Journal of the Korean association of regional geographers
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• v.17 no.6
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• pp.649-665
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• 2011

Estuary of River Nakdong(in south-eastern coast of Korean Peninsula) is the most representative site of delta in Korea. This study is to elucidate morpho-structural background associated with the embayment area and sedimentation processes, having allowed development of the delta. In this area, Great morphological trait of the embayment area had been formulated by differential erosion exploiting regional fracture system(NNE-SSW, NNW-SSE, E-W,...) of tectonic origin. For this reason, outline of the embayment basin shows quadrangular plan, and ridges and dissected valleys of neighbouring mountains draw frequently morphological lineament pattern. At the last glacial age when delta deposit had not yet filled the actual embayment basin of the Nakdong, mechanical weathering(frost shattering) and mass-movement processes had provided detritus materials composed of blocks, boulders on bottom the basin. With the postglacial transgression in the Holocene, the basin had been submerged, then began to be filled with fluvio-marine deposits from Kimhae-Yangsan area toward actual estuarine zone, so that Nakdong delta have been formed. Analysis and synthesis of from hundreds of boring data of the delta area reveal that progression of delta formation have been accompanied with the development of barrier islands. If the barrier islands had grown as forming a plural row, then their intervals have posteriorly filled with another fluvio-marine deposits. Besides, it shows that delta deposits are essentially alluvial. However, at the periphery of the delta, intervention of fine marine deposits is frequently found.

• Korean Journal Plant Pathology
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• v.3 no.3
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• pp.174-179
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• 1987

Four thousand eight hundred and eighty five isolates of Pyricularia oryzae were obtained from the diseased rice specimens collected from various areas of Korea for race identification during 1978 - 1985. A total of 15 races inculding 6 races pathogenic to Tongil lines, 2 T-races, 5 C-races and 2 N-races was identified using a old Japanese differential set during 1978-1980. Since 1981, number of races identified by a Korean differential set was 18 races which were composed of 11 KI-races pathogenic to either Tongil lines or Japonica cultivars and 8 KJ-races pathogenic to only Japonica cultivars. The prevalent race was $N-2^{+t}$ during 1978-1979 and race KJ-301 since 1980, respectively. Races KI-315a and KI-315b pathogenic to most of Tongil lines were identified in 1983. being widely distributed to date. Races KJ-105 and KJ-201 pathogenic to the cultivars possessing resistance genes Pi-k and Pi-i were prevalent in Gangweon province, whereas race KI-315b was prevalent in Chungbug and Jeonnam districts.

• Journal of the Korean association of regional geographers
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• v.18 no.1
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• pp.71-85
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• 2012

Marriage Immigrants have greater impact on local communities than migrant workers and foreign students, all the more because their children are relatively more important. Therefore, this study aims to inquire into the fundamental cause on the choice of residential location of marriage immigrants. Residential segregation is often considered to be one of the social problems that intensify locality of residential district. Although migrant workers and foreign students cannot freely decide their residential location at the outset, they could change their residence later on. However marriage immigrants are not free from the residential location choice continuously. The intentional(involuntary) residential segregation brings differential residence of marriage immigrants. The residential segregation of marriage immigrants is concerned with the close relationship of their ethnic background and the community characteristic with focus on Vietnamese and Filipino. The results of this study could be used basic guideline for community development policy for marriage immigrants.

• Journal of the Korean association of regional geographers
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• v.21 no.1
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• pp.114-136
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• 2015

Manufacturing FDI is mainly conducted by establishing production firms in the host country. The foreign branch facilities which are closely connected to headquarters in the home countries through the global supply chain have decisive effects on the integration of global production system and on the pattern changes in international logistics. Therefore, the study on the development process of manufacturing supply chain through FDI can be the key factor to understand the global production and international logistics system. This study analyzes the spatial and temporal patterns of direct investments in China by Korean companies in the manufacturing sectors. The results show a great deal of differential in periods and regions in investment. At the early period of Korean manufacturing FDI, the coast provinces in China which are adjacent to Korean peninsula were main investment target regions. However recently, coastal and inland provinces far away from Korea have been important for attracting Korean manufacturing capital. If further affiliated studies are done, the results of this study would be more beneficial to understand the logistics flows of regional supply chain based on the manufacturing FDI.

• Development and Reproduction
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• v.23 no.4
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• pp.313-322
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• 2019

The epididymal fat pad is a male gonadal adipocyte tissue and is histochemically separated into distal and proximal parts. The development of epididymal fat during postnatal period has not been examined in detail. A previous research showed that expression of adipocyte-associated molecules in the distal epididymal fat of mouse is generally increased as postnatally aged. In the present study, expressional patterns of same adipocyte-associated molecules in the mouse proximal epididymal fat at 2, 5, 8, and 12 months of age were studied by quantitative real-time PCR analysis and were compared with those in the distal epididymal fat. The expressional levels of peroxisome proliferator-activated receptor gamma (Pparg), lipoprotein lipase (Lpl), and fatty acid synthase (Fasn) at 5 months of age were significantly lower than those at 2 months of age, while transcript level of leptin (Lep) at 5 months was higher than that at 2 months of age. The transcript levels of all molecules at 8 months of age were significantly increased, compared with those at 2 and 5 months of age. At 12 months of age, expression of delta like non-canonical Notch ligand 1 (Dlk1) was further significantly increased, while there was no change on the transcript level of Pparg and significant decreases of Fabp4, Retn, Lpl, Lep, Fasn, and adiponectin (Adipoq) transcript levels. The current findings show that expressional patterns of molecules associated with adipocyte in the proximal epididymal fat is somewhat different with those of the distal epididymal fat, suggesting the existence of regional variance in the epididymal fat.