• Journal of Nutrition and Health
• /
• v.36 no.7
• /
• pp.711-719
• /
• 2003

The effects of taurine, carnitine or glutamine supplementation on endurance exercise performance along with related fatigue factors were evaluated in male college students in the Department of Physical Education, who's maximal oxygen consumption rates (VO$_2$max) were equivalent to those of endurance athletes. Twenty four subjects were randomly divided into 4 groups (n=6), and given placebo, taurine (4 g/day), carnitine (4 g/day), or glutamine (4 g/day) tablets for 2 weeks. Subjects could run 6.9 min or 9.0 min longer until exhausted on a treadmill at the intensity of 75% VO$_2$max following taurine or camitine supplementation for 2 weeks, respectively, compared to the value measured prior to each supplementation. Glutamine or placebo supplementation did not improve the endurance exercise performance based on the running time until exhausted on a treadmill. Serum lactate concentrations measured 1 hr after the initiation of the endurance exercise, as well as at all-out state tended to be decreased by taurine, carnitine, or glutamine supplementation, and were significantly lowered (43% decrease) by carnitine supplementation (p < 0.05). Taurine supplementation significantly reduced the serum inorganic phosphorus concentration measured at all-out state (14% decrease, p < 0.05), while carnitine supplementation significantly lowered the resting state serum inorganic phosphorus level (20% decrease, p < 0.05). Taurine (32% reduction) or carnitine (23% reduction) supplementation significantly decreased serum ammonia concentration measured at all-out state (p < 0.05). From these results, 4 g/day of taurine or carnitine supplementation appears to improve the endurance exercise performance and related human fatigue factors.

• Proceedings of the Korean Nutrition Society Conference
• /
• 2002.11a
• /
• pp.167-167
• /
• 2002

• Fisheries and Aquatic Sciences
• /
• v.17 no.2
• /
• pp.255-261
• /
• 2014

An 8-week feeding trial was conducted to investigate the effects of dietary taurine supplementation on the growth performance of juvenile rock bream, Oplegnathus fasciatus. Triplicate groups of 25 fish averaging $2.72{\pm}0.04$ g ($mean{\pm}SD$) were fed one of six experimental diets prepared by adding taurine at 0%, 0.25%, 0.5%, 1.0%, 1.5% and 3.0% (Control, $Tau_{0.25}$, $Tau_{0.5}$, $Tau_{1.0}$, $Tau_{1.5}$ and $Tau_{3.0}$, respectively). At the end of the feeding trial, the weight gain, specific growth rate and protein efficiency ratio of fish fed the $Tau_{0.5}$, $Tau_{1.0}$ and $Tau_{1.5}$ diets were significantly higher (P < 0.05) than those of fish fed the Control and $Tau_{0.25}$ diets. The feed efficiency of fish fed the $Tau_{0.5}$ diet was significantly higher than that of fish fed the Control, $Tau_{0.25}$ and $Tau_{3.0}$ diets. Fish fed the $Tau_{1.0}$ diet had higher whole-body crude protein content than fish fed the Control diet, while the crude lipid content of fish fed the $Tau_{1.5}$ and $Tau_{3.0}$ diets was significantly lower than that of fish fed the Control and $Tau_{0.25}$ diets. An ANOVA suggested that the optimum level of dietary taurine supplementation to improve growth and reduce the body lipid contents of juvenile rock bream, O. fasciatus, was 0.5%, while a broken line analysis of weight gain indicated a level of 0.62%.

• Journal of Nutrition and Health
• /
• v.33 no.2
• /
• pp.124-133
• /
• 2000

This study evaluated the effects of chronic ethanol consumption and/or taurine supplementation on hepatic total, phospholipid fatty acid composition and the metabolism of rats fed one of three purified liquid diets for 8 weeks. the rats followed either the control diet (CD, ethanol-free and taurine-free diet); ethanol diet (ED, CD+ 50g ethanol/L) or ethanol-taurine diet (ETD, ED+3.75g taurne/L). Chronic ethanol consumption and/or dietary taurine supplementation were associated with altered hepatic total and phospholipid fatty acid composition. compared to the values for the control rats, ED or ETD significantly decreased the percentage of total monounsaturated fatty acids ($\Sigma$MUFA), and increased the percentage of total polyunsaturated fatty acids ($\Sigma$PUFA) of hepatic total lipids(p〈0.01). Percentages of 14:0(P〈0.01) and 16:0(p〈0.001) were sigificantly lower, and those of 18:0(p〈0.01), 20:0(p〈0.001), 20:3$\omega$6(p〈0.01) and 22:4$\omega$6(p〈0.01) in hepatic total fatty acid compositions were oserved in rats fed ETD versus those fed ED or ETD. No significant differences in hepatic total fatty acid compositions were observed in rats fed ETD versus those fed ED. Percentages of 24:0(p〈0.01), 16:1(p〈0.05), 20:1(p〈0.01), 18:2$\omega$6(p〈0.01) and 18:3$\omega$3(p〈0.05) in hepati phospholipids were significantly higher, and those of 14:0(p〈0.01), 16:0(p〈0.001), 20:3$\omega$3(p〈0.05) in hepatic phospholipids were significantly higher, and those of 14:0(p〈0.01), 16:0(p〈0.001), 20:3$\omega$3(p〈0.001), 22:6$\omega$3(p〈0.001) and $\Sigma$$\omega$3(P〈0.001) were significantly lower in rats fed ED or ETD compared to the values for the control rats. The Δ5 desaturation index(20:3$\omega$6⇒20:4$\omega$6) and elongation index (20:5$\omega$3⇒22:5$\omega$3) of hepatic phospholipid index (20:3$\omega$6⇒20:4$\omega$6) and decreased Δ4 desaturation index (22:5$\omega$3⇒22:6$\omega$3) compared to the values for the ED rats. These changes in hepatic fatty acid composition induced by chronic ethanol consumption and/or taurine supplementation might be associated with the modulations of physical properties of the hepatic cell membrane and its sensitivity to peroxidation damage.

• Korean Journal of Poultry Science
• /
• v.29 no.2
• /
• pp.141-148
• /
• 2002

Two experiments were conducted to investigate the effects of supplemental feather digests on the growth of broiler chicks and taurine content in the broiler meat. In experiment 1, a total of 40 broiler chickens(Ros $s_{R}$) were assigned to four dietary treatments: control(T1), regular feather meal(FM) diet(R-FM,T2), NaOH treated FM diet(NaOH-FM,T3), HNO) treated FM diet($HNO_{3}$ -FM, T4). In experiment 2, a total of 70 broiler chickens were assigned to seven dietary treatments: T1 to t4(same as those of Exp. 1), modified $HNO_{3}$ treated FM diet(M- $HNO_{3}$-FM, T5), hair meal diet(HM, T6) and 0.22% cystine supplemented diet(CYS, T7). Feather meals and hair meal were supplemented at the level of 5% in the diet. In experiment 1 and 2, weight gain of chicks frd with R-FM or NaOH-FM tended to be higher than control or $HNO_{3}$ -FM. In experiment 2, weight gain of chicks frd with CYS was the highest followed by R-FM, M-HN $O_3$-FM, NaOH-FM, control, HM and $HNO_{3}$ -FM. In experiment 1, taurine content in breast muscle of chicks fed NaOH-FM was sogmofocamtly higher(P<0.05) than control. In experiment 2, taurine content in breast muscle of chicks fed NaOH-FM and CYS tended to be higher than other groups. Taurine content in leg muscle was significantly different among treatments as NaOH-FM and R-FM being highest followed by M- $HNO_{3}$-FM, CYS, control, $HNO_{3}$ -FM and HM. Taurine content in the liver(Exp. 1 and 2) and heart(Exp. 2) were not significantly affected by the supplemental feather digests. These results indicated that 5% NaOH-FM in the diet was effective in increasing taurine content in breast and leg muscle of broiler chicks.s.

• Korean Journal of Poultry Science
• /
• v.37 no.4
• /
• pp.337-345
• /
• 2010

The current study was conducted to estimate the effect of dietary taurine on performance, egg quality, blood parameter, liver lipids and lipid peroxidation level of laying hens fed high fat diet. Two hundred eighty laying hens, forty five weeks of age, were allocated to four treatment groups with seven replicates of 10 each per treatment for 4 weeks. Experimental diets were assigned to each of the four groups: control diet (CON), CON with 0.5% taurine (CT), CON with 5% soybean oil (HF), and CON with 5% soybean oil and 0.5% taurine (HFT). Egg weight was significantly lower in the control than the CT (P<0.05). However, the HFT was similar to the level compared to both control and HF. Serum concentrations of total cholesterol, triglyceride and glutamic oxaloacetic transaminase (GOT) were significantly decreased by about 30%, 36% and 20%, respectively in the HFT compared to the HF (P<0.05). In the liver tissue, triglyceride concentration tended to be lower by about 28% in the HFT compared to the HF (P<0.05). The hepatic lipid peroxidation level was significantly decreased by about 25% in the HFT compared to the HF (P<0.05). These results indicated that taurine supplementation improved the serum total cholesterol, triglyceride concentration, and decreased hepatic lipid peroxidation level without affecting performance in laying hens fed high fat diet.

• Fisheries and Aquatic Sciences
• /
• v.19 no.10
• /
• pp.40.1-40.14
• /
• 2016

Background: Due to the paucity of oceanic resources utilized in the preparation of diets for cultured fish, commercial feed producers have been trying to replace fishmeal (FM) using alternative protein sources such as vegetable protein meals (VMs). One of the main drawbacks of using VMs in fish feed is related to the presence of a variety of anti-nutritional factors, which could trigger an inflammation process in the distal intestine. This reduces the capacity of the enterocytes to absorb nutrients leading to reduced fish growth performances. Methods: We evaluated the mitigating effects of butyrate and taurine used as feed additives on the morphological abnormalities caused by a soybean meal (SBM)-based diet in the distal intestine of sea bass (Dicentrarchus labrax). We used three experimental diets, containing the same low percentage of FM and high percentage of SBM; two diets were supplemented with either 0.2% sodium butyrate or taurine. Histological changes in the intestine of fish were determined by light and transmission electron microscopy. Infiltration of $CD45^+$ leucocytes in the lamina propria and in the submucosa was assessed by immunohistochemistry. We also quantified by One-Step Taqman$^{(R)}$ real-time RT-PCR the messenger RNA (mRNA) abundance of a panel of genes involved in the intestinal mucosa inflammatory response such as $TNF{\alpha}$ (tumor necrosis factor alpha) and interleukins: IL-8, IL-$1{\beta}$, IL-10, and IL-6. Results: Fish that received for 2 months the diet with 30% soy protein (16.7% SBM and 12.8% full-fat soy) developed an inflammation in the distal intestine, as confirmed by histological and immunohistochemistry data. The expression of target genes in the intestine was deeply influenced by the type of fish diet. Fish fed with taurine-supplemented diet displayed the lowest number of mRNA copies of IL-$1{\beta}$, IL-8, and IL-10 genes in comparison to fish fed with control or butyrate-supplemented diets. Dietary butyrate caused an upregulation of the $TNF{\alpha}$ gene transcription. Among the quantified interleukins, IL-6 was the only one to be not influenced by the diet. Conclusions: Histological and gene expression data suggest that butyrate and taurine could have a role in normalizing the intestinal abnormalities caused by the SBM, but the underling mechanisms of action seem different.

• Proceedings of the Korean Nutrition Society Conference
• /
• 2001.05a
• /
• pp.161.2-161
• /
• 2001

• Journal of the East Asian Society of Dietary Life
• /
• v.11 no.2
• /
• pp.151-159
• /
• 2001

This study was conducted to determine the image of functional foods and the meal patterns for health behavior of 242 persons in Daegu area. Anthropometric data showed that female and male were 38, and 204 respectively. The most BMI group was standard group(55.4% )The most eaten functional foods were Lactobicilli goods while the lowest functional foods were Taurine goods. The highest functional food image score on the basis of Likert's 5 scales was 3.89(expensive) and the lowest score was 2.98 (experienced in eating functional food). Accepted food groups were significantly associated with eating rate of protein food and age(p < 0.01),eating rate of cabohydrate foods and sex(p < 0.05), eating rate of mineral foods and monthly average income, eating rate of vitamin foods and sex.

• Proceedings of the Korea Society of Poultry Science Conference
• /
• 2001.11a
• /
• pp.97-98
• /
• 2001

In Experiment 1, two hundred ten hatched broiler chickens(Ross) were assigned to seven dietary treatments for 5weeks. Each treatment was consisted of 3 replications with 10 birds per replication. Control diet was formulated 22%CP and 3,150kcaIME/kg for starter diet, 19%CP, 3,200kca1ME/kg for finisher diet. Euglena gracilis was added to control diet at the level of 0.25, 0.5, 1.0% and Euglena bleached(DHA enriched) at the level of 0.5, 1.0, 2.0% in the diet. 0 Experiment 2, two hundred fifty hatched broiler chickens(Ross) were assigned to five dietary treatments: T1; control, T2: T1 + Euglena gracilis(DHA enriched)0.5%, T3; T1 + Euglena gracilis(DHA enriched)1.0%, T4: T1 + Euglena bleached(DHA enriched)0.5%,T5: T1 $.$Euglena bleached(DHA enriched)1.0%. In Experiment 1, 2.0% Euglena bleached treatment showed highest DHA level in breast muscle(P<0.05), In Experiment 2, 1.0% Euglena bleached treatment showed highest EPA, Lignoceric acid and DHA level in breast muscle(P<0.05).