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Effects of Dietary Supplementation of Taurine, Carnitine or Glutamine on Endurance Exercise Performance and Fatigue Parameters in Athletes  

이해미 (연세대학교 식품영양학과)
백일영 (연세대학교 체육교육학과)
박태선 (연세대학교 식품영양학과)
Publication Information
Journal of Nutrition and Health / v.36, no.7, 2003 , pp. 711-719 More about this Journal
Abstract
The effects of taurine, carnitine or glutamine supplementation on endurance exercise performance along with related fatigue factors were evaluated in male college students in the Department of Physical Education, who's maximal oxygen consumption rates (VO$_2$max) were equivalent to those of endurance athletes. Twenty four subjects were randomly divided into 4 groups (n=6), and given placebo, taurine (4 g/day), carnitine (4 g/day), or glutamine (4 g/day) tablets for 2 weeks. Subjects could run 6.9 min or 9.0 min longer until exhausted on a treadmill at the intensity of 75% VO$_2$max following taurine or camitine supplementation for 2 weeks, respectively, compared to the value measured prior to each supplementation. Glutamine or placebo supplementation did not improve the endurance exercise performance based on the running time until exhausted on a treadmill. Serum lactate concentrations measured 1 hr after the initiation of the endurance exercise, as well as at all-out state tended to be decreased by taurine, carnitine, or glutamine supplementation, and were significantly lowered (43% decrease) by carnitine supplementation (p < 0.05). Taurine supplementation significantly reduced the serum inorganic phosphorus concentration measured at all-out state (14% decrease, p < 0.05), while carnitine supplementation significantly lowered the resting state serum inorganic phosphorus level (20% decrease, p < 0.05). Taurine (32% reduction) or carnitine (23% reduction) supplementation significantly decreased serum ammonia concentration measured at all-out state (p < 0.05). From these results, 4 g/day of taurine or carnitine supplementation appears to improve the endurance exercise performance and related human fatigue factors.
Keywords
taurine; carnitine; glutamine; endurance exercise performance; human fatigue parameters;
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1 Saito S, Tasaki Y, Tagami K, Suzuki M. Muscle glycogen repletion and preexercise glycogen content. Eur J Appl Physiol 68:483-488, 1993   DOI
2 Effects of L-carnitine loading on the aerobic and anaerobic performance of endurance athletes /
[ Marconi,C.;Sassi,G.;Carpinelli,P. ] / Eur. J. Appl. Physiol.   DOI
3 Effects of taurine on the metabolism under physical exercise /
[ Watanabe,M.:Minato,K.;Ono,M. ] / Sulfur Amino Acids
4 The effects of oral supplementation with L-carnitine on maximum and submaximum exercise capacity /
[ Grieg,C.;Finch,K.M.;Jones,D.A.;Coper,M.;Sargeant,A.J.;Forte,C.A. ] / Eur J Appl Physiol   DOI
5 Plasma glutamine and upper respiratory tract infection during intensified training in swimmers /
[ Mackinnon,L.T.;Hooper,S. ] / Med. Sci. Sports Exerc.   DOI   ScienceOn
6 Muscle glycogen repletion and pre-exercise glycogen content /
[ Saito,S.;Tasaki,Y.;Tagami,K.;Suzuki,M. ] / Eur. J. Appl. Physiol.
7 The increase of perceived excertion, aches and pain in legs, heart and blood lactate during exercise on a bicycle ergometer /
[ Borg,G.;Ljunggren,G.;Ceci,R. ] / Eur. J. Appl. Physiol. Occup. Physiol.   DOI
8 Depression of Plasma glutamine concentration after exercise stress and its possible influence on the immune system /
[ Keast,D.;Arstein,D.;Harper,W.;Fry,R.W.;Mortion,A.R. ] / Med J Aust
9 Respiratory chain enzymes in muscle of endurance athletes:effects of L-carnitine /
[ Huertas,R.;Campos,Y.;Diaz,A.E. ] / Biochem. Biophys. Res. Commun.   DOI   ScienceOn
10 Kinetics of carnitine dependent fatty acid axidation: implications, for human carnitine deficiency /
[ Long,C.S.;Haller,R.G.;Foster,D.W.;McGarry,J.D. ] / Neurology   DOI
11 Effects of taurine on lipolytic activity of adipose tissue in rats /
[ Tanaka,H.:Watanabe,M.;Takekura,M.;Ono,M. ] / Sulfur Amino Acids
12 Thermal effects of prolonged treadmill exercise in the heart /
[ Gisolfi,C.;Copping,J. ] / Med. Sci. Sports
13 Exercise-induced hyperammonemia:peripheral and central effects /
[ Banister,E.W.;Cameron,B.J.C. ] / Int. J Sports Med.   DOI
14 Inhibition of cholinergic response by taurine in frog isolated skeletal muscle /
[ Lehmann,A.;Hamberger,A. ] / J Pharm Pharmacol   DOI
15 Effects of acute moderate-intensity exercise on arnitine metabolism in men and women /
[ Lennon,D.L.F.;Startman,F.W.;Shrago,E.;Nagle,F.F.;Madden,M.;Hanson,P.;Carter,L. ] / J. Appl. Physiol.
16 Influence of L-carnitine administration on maximal physical exercise /
[ Vecchit,L.;Di,Lisa F.;Pieralisi,G.;Ripari,P.;Menabo,R.;Giamberardino,M.A. ] / Eur. J. Appl. Physiol.   DOI
17 Effects of taurine on glycolytic and axidative enzyme activities of rat skeletal muscles /
[ Takekura,H.;Tanaka,H.;Watanabe,M.;Yoshica,T.;Ono,M. ] / Sulfur Amino Acids
18 Carnitine and its role in metabolism /
[ Silipran,N. ] / Acta. Med. Rom.
19 Maximal oxygen intake and normorgraphic assessment of functional aerobic impairment in cardiovascular disease /
[ Bruce,R.A.;Kusumi,F.;Hosmer,D. ] / Am. Heart. J.   DOI   ScienceOn
20 Thin filament modulation of cross-bridge transition measured by photogeneation of Pi in skeletal muscle fibers /
[ Walke,J.W.;Lu,Z.;Swartz,D.;Moss,R.L. ] / Biophys. J.
21 Verifying the validity of fatigue elements changes following absolute exercise intensities /
[ Paik,I.Y.;Kim,J.K.;Chun,Y.S.;Oho,H.J. ] / Kor. J. Physiol. Edu.
22 The effects of pH on carbohydrate changes in isolated anaerobic frog muscle /
[ Ronzoni,E.;Kerly,M. ] / J. Biol. Chem.
23 Ammonia intoxification: changes of brain levels of putative neurotransmitter and related compounds and its relevance to hepatic coma /
[ Koyuncuoclu,H.;Keyer,M.;Simsek,S.;Sagduyu,H. ] / Pharmacol. Res. Commun.   DOI   ScienceOn
24 Effects of L-carnitine submaximal exercise metabolism after depletion of muscle glycogen /
[ Decombaz,J.;Deriaz,O.;Acheson,K.;Gmuender,B.;Jequier,E. ] / Med. Sci. Sports Exerc.
25 A communicational link between skeletal muscle, brain, and cells of the immune system /
[ Parry-Billings,M.;Blomstrand,E.;AcAndrew,N.;Newsholme,E.A. ] / Int J Sports Med
26 Neutral control of the circulation during exercise /
[ Mitchell,J.H. ] / Med. Sci. Sports Exerc.
27 Physiological actions of taurine /
[ Huxtable,R.J. ] / Physiol. Rev.
28 Effects of caffeine ingestion on utilization of muscle glycogen and lipid during leg ergometer cycling /
[ Essig,D.A.;Costill,D.L.;Van,Handel,O.J. ] / Int. J. Sports Med.   DOI
29 Carnitine in muscle, serum, and urine of nonp-rofessional athletes: effects of physial exercise, training, and L-lcarnitine administration /
[ Arenas,J.:Ricoy,J.R.;Encinas,A.R. ] / Muscle Nerve   DOI   ScienceOn
30 Carnitine /
[ Bieber,L.L. ] / Ann. Rev. Biochem.   DOI   ScienceOn
31 Stimulatory effect of glutamine on glycogen accumulation in Human skeletal muscle /
[ Varnier,M.;Leese,G.P.;Thompson,J.;Rennie,M.J. ] / Am J Physiol
32 Effect of rigor and cycling cross-bridges on the structure of troponin C and Ca²+ affinity of the Ca²+ -specific regulatory sites in skinned rabbit psoas fibers /
[ Guth,H.;Potter,J.D. ] / J. Biol. Chem.
33 Glutamine, exercise and immune function /
[ Walsh,N.P.;Blannin,A.K.;Robson,P.J.;Gleeson,M. ] / Sports Med.   DOI   ScienceOn
34 Ammonia: assessment of its action in postsunaptic inhibition as a cause of convulsion /
[ Iles,J.F.;Jack,J.J.B. ] / Brain   DOI   ScienceOn
35 Effects of L-carnitine on the pyruvate dehydrogenase complex and carnitine palmitoyl transferase activities in muscle of endurance athletes /
[ Arenas,J.;Huertas,R.;Campos,Y.;Daiz,A.E.;Vilalon,J.M.;Vilas,E. ] / FEBS Lett   DOI   ScienceOn
36 Does glutamine have a role in reducing infections in athletes? /
[ Castell,L.M.;Poortmans,J.R.;Newsholme,E.A. ] / Eur J Appl Physiol   DOI