• Nutrition Research and Practice
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• 제9권5호
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• pp.496-502
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• 2015

BACKGROUND/OBJECTIVES: This study was performed to investigate the association between the dietary intake of fish and shellfish, and omega-3 polyunsaturated fatty acids (PUFAs) and cardiovascular disease (CVD) risk factors in the middle-aged Korean female patients with Type 2 diabetes (T2D). SUBJECTS/METHODS: A cross-sectional analysis was performed with 356 female patients (means age: 55.5 years), who were recruited from the Huh's Diabetes Clinic in Seoul, Korea between 2005 and 2011. The dietary intake was assessed by a validated semi-quantitative food frequency questionnaire and analyzed using the Computer Aided Nutritional Analysis program (CAN-Pro) version 4.0 software. RESULTS: In a multiple regression analysis after the adjustment for confounding factors such as age, BMI, duration of diagnosed T2D, alcohol consumption, fiber intake, sodium intake, and total energy intake, fish and shellfish intake of the subjects was negatively associated with triglyceride and pulse wave velocity (PWV). Omega-3 PUFAs intake was negatively associated with triglyceride, systolic blood pressures, diastolic blood pressures, and PWV. The multiple logistic regression analysis with the covariates showed a significant inverse relationship between the omega-3 PUFAs consumption and prevalence of hypertriglyceridemia [OR (95% CI) for greater than the median compared to less than the median: 0.395 (0.207-0.753)]. CONCLUSIONS: These results suggest that the consumption of fish and shellfish, good sources of omega-3 PUFAs, may reduce the risk factors for CVD in the middle-aged female patients with T2D.

• Journal of Nutrition and Health
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• 제21권4호
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• pp.232-241
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• 1988

This study was to investigate the effect of calcium supplementation on the reduction of blood pressure in normotensive young adults. Fortyseven healthy college students(23 male and 24 female) were divided into Ca and placebo groups, and were orally given with calcium(1g/day, 2.5g as CaCO3) and placebo, respectively, for 20 weeks. Blood pressure was measured by Korotokoff method in seated position every two weeks. Average daily dietary calcium intakes of the subjects were 626-643mg in men and 513-552mg in women. Average initial level of serum calcium of the subjects belonged to normal range. 1. Both systolic and diastolic blood pressure(SBP and DBP) of Ca group showed significant continuously decreasing tendency from 6-8 weeks until final 20 weeks of the supplementation in both men and women. But placebo groups did not. Comparing with the basal value, reduction of SBP and DBP after 20 weeks were 6.53$\pm$4.30%(8.9mmHg) and 8.10$\pm$3.30%(7.4mmHg) in men, and 6.56$\pm$2.41%(8.1mmHg) and 7.33$\pm$3.75%(6.2mmHg) in women. The blood pressure lowering effect of calcium supplementation seemed to be greater in the subjects with higher basal SBP. 2. Serum calcium was significantly increased by calcium supplementation in both men and women, and showed significant negative correlation with SBP(r=-.213) and DBP(r=-.301) in women. Serum Ca/Mg ratio of Ca group was also elevated and showed significant negative correlation with SBP(r=-.174) and DBP(r=-.194) in total subjects. 3. Urinary excretion of Na did not show any significant changes by calcium supplementation in both men and women and showed no correlations with blood pressures.

• 임상이비인후과
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• 제29권2호
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• pp.182-189
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• 2018

Background and Objectives : There were few literatures about the relationship between upper airway disorders and cardiovascular risk factors such as hypertension, although an association between impaired lower respiratory function and cardiovascular alterations was often reported. Our purpose was to assess the relationships between chronic sinusitis and hypertension. Materials and Methods : Three hundred subjects with bilateral chronic sinusitis who underwent functional endoscopic sinus surgery between 2015and 2017 were evaluated. Six hundred forty subjects without any nasal diseases were enrolled as a control group. Blood pressure and body mass index (BMI) were measured using a standardized method, and subjects were asked about current use of any antihypertensive medication, history of diabetes, smoking and alcohol drinking habits.Sinusitis group was assessed by nasal endoscopic examination, paranasal sinus CT scan and allergy test. Results : Average systolic and diastolic blood pressures were statistically significantly higher in subjects with sinusitis than control group. Chronic rhinosinusitis was associated with a 1.415-fold (95% confidence interval 1.053-1.930) increased hazard of hypertension after multivariate adjustment. Conclusions : These results suggest that sinusitis is associated with high blood pressure. Therefore patients with sinusitis may need special attention for blood pressure control. Further studies need to be performed to elucidate the pathogenesis behind such associations.

• 한국식품영양과학회지
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• 제20권4호
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• pp.346-353
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• 1991

전남 순천시에 거주하는 60세 이상의 노인 438명 (남자 179명, 여자 259명)을 대상으로 하여 식습관, 체위, 치아결손정도, 혈색소농도, 적혈구용적비, 혈압 및 질병보유상태를 조사하였고 식습관 점수와 제 변인간의 상관관계를 검토하였다. 식습관은 남자노인이 여자노인에 비하여 양호하였으며 과일류, 계란류, 육류 및 어류, 두류의 섭취빈도가 남자노인이 높았다. 평균 체중과 신장은 한국인 체위표준치보다 낮았으나 평균 BMI는 남녀노인 모두 정상 범위를 보였고 평균 비만율은 남녀노인 각각 3.5%, 8.2%이었다. 평균 혈색소농도와 적혈구용적비는 남자노인의 경우 WHO기준보다 낮았고 여자노인은 정상 범위이었다. 따라서 WHO 혈색소농도 기준에 따른 빈혈율은 남자노인이 42.0%, 여자노인이 34.7%로 남자노인의 빈혈율이 더 높았으며 남녀노인 모두 빈혈이 만연되어 있었다. 평균 수축기 및 확장기혈압은 남녀노인 모두 정상 범위이었으나 WHO 기준에 의한 고혈압율은 남녀노인 각각 15.6%, 16.7%이었다. 질병을 보유한 경우는 남녀노인 각각 78.2%, 86.7%로 높았고 신경통을 비롯하여 순환기계질환, 호흡기계질환, 당뇨병, 관절염 등이 주요 질환이었다. 식생활이 양호할수록 바람직한 체위를 유지하였으며 빈혈율도 낮았다. 한편 상완피하지방두께가 두꺼울수록 빈혈율이 높았고 혈압도 높았으며, 혈압이 높을수록 질병보유율이 높은 상관을 나타내었다.

• Nutrition Research and Practice
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• 제9권2호
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• pp.199-206
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• 2015

BACKGROUND/OBJECTIVE: Even though the prevalence of metabolic syndrome in adolescents is increasing, little is presently known about this syndrome in adolescents. This study aimed to cluster metabolic risk factors as well as examine the associations between identified patterns and nutrient intake using data from the Korean National Health Examination and Nutritional Assessment (KNHANES). SUBJECTS/METHODS: A total of 2,958 subjects aged 10 to 18 years along with both biochemical and dietary data information were obtained from KNHANES 2007-2010. Six components of metabolic syndrome were used to identify any patterns via factor analysis. Individuals were categorized into quartile groups according to their pattern score. RESULTS: Three clustering patterns with high loadings were identified and named as follows: 1) high blood pressure, 2) dyslipidemia, and 3) glucose abnormality patterns. The high blood pressure pattern showed high loadings of systolic and diastolic blood pressures, the dyslipidemia pattern showed high loadings of triglyceride and HDL-cholesterol levels, and the glucose abnormality pattern showed high loadings of fasting blood glucose levels. Intakes of fat and riboflavin were significantly decreased, whereas those of sodium and niacin were significantly increased across the quartiles in the dyslipidemia pattern. No nutrient intake except that of thiamin was significantly associated with the high blood pressure or glucose abnormality pattern. CONCLUSION: Our findings show that metabolic syndrome risk factors in the Korean adolescent population are characterized by three distinct patterns, which are differentially associated with dietary factors. Characterizing metabolic risk factors and providing specific dietary guidelines for target groups are important.

• 대한의용생체공학회:의공학회지
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• 제38권3호
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• pp.111-115
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• 2017

Blood pressure is one of the important vital signs for monitoring the medical condition of a patient. Automated NIBP(non-invasive blood pressure) monitoring devices calculate systolic and diastolic blood pressures from the oscillation in cuff pressure caused by a pulsation of an artery. To validate the NIBP devices, we developed a simulator to supply the oscillometric waveforms obtained from human subjects. The simulator provided pressure pulses to device-under-test and device readings were compared to the auscultatory references. Fully automated simulation system including OCR(optical character recognition) were developed and used for NIBP monitoring devices. The validation results using the simulator agreed well with previous clinical validation. More validation studies using the standardized oscillometric waveforms would be required for the replacement of clinical trials to validate a new automated NIBP monitoring device.

• 대한간호학회지
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• 제48권2호
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• pp.221-231
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• 2018

Purpose: This study aimed to compare the effects of three interventions on pain, blood pressure, and pulse rate during infiltration anesthesia in patients about to undergo gamma knife surgeries. Methods: The three interventions employed in a university-affiliated Hospital in J City, South Korea were as follows: EMLA cream plus Vapocoolant spray (Vapocoolant, n=30), EMLA cream plus 10.0% Lidocaine spray (Lidocaine, n=30), and EMLA cream only (EMLA, n=30). The equivalent control-group pre test - post test study design was used. Pain was assessed subjectively using the numeric rating scale (NRS) and objectively using a Galvanic Skin Response (GSR) tester. NRS scores were assessed after infiltration anesthesia and the GSR was assessed during infiltration anesthesia. Blood pressure and pulse rate were assessed twice: before and after infiltration anesthesia. Data were collected between August 3, 2016 and March 24, 2017. Results: NRS scores after infiltration anesthesia and the GSR during infiltration anesthesia were significantly lower in the Vapocoolant group than in the Lidocaine and EMLA groups (F=13.56, p<.001 and F=14.43, p<.001, respectively). The increase in systolic blood pressure (F=4.77, p=.011) and in pulse rates (F=4.78, p=.011) before and after infiltration anesthesia were significantly smaller in the Vapocoolant group than in the Lidocaine and EMLA groups; however, no significant differences were observed in diastolic blood pressures (F=1.51, p=.227). Conclusion: EMLA cream plus Vapocoolant spray was the most effective intervention to relieve pain and to lower increase in systolic blood pressure and pulse rate caused by infiltration anesthesia for stereotactic frame fixation. Thus, application of Vapocoolant spray in addition to EMLA cream is highly recommended as a nursing intervention for patients undergoing gamma knife surgeries.

• 가정간호학회지
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• 제15권1호
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• pp.29-36
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• 2008

Purpose: The purpose of this study was to develop and evaluate an exercise program for elderly community-dwelling adults. The program was intended to improve joint flexibility and self-efficacy and to reduce blood pressure. Methods: A quasi-experimental, nonequivalent control group pre-post test design was used to evaluate the program. Twenty-six subjects were enrolled in the experimental group, and twenty-seven subjects were enrolled in the control group. The program was carried out between March 6 and May 4, 2006. The experimental group subjects participated in the exercise program once a week for eight weeks and received a phone call weekly to encourage self-exercise at home. Results: After program participation, the experimental group subjects showed significantly higher flexibility in the right shoulder joint and higher self-efficacy than subjects in the control group. Systolic and diastolic blood pressures were also significantly lower in the experimental group subjects. However, there were no significant differences in knee joint flexibility between the two groups after the intervention. Conclusion: The eight-week exercise program was effective in decreasing blood pressure and improving joint flexibility and self-efficacy in older adults. This study suggests that this exercise program could be utilized as an effective independent nursing intervention modality in elderly persons.

• 대한지역사회영양학회지
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• 제11권2호
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• pp.271-278
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• 2006

It has been suggested that isoflavones protect the cardiovascular system, in part by attenuating blood pressure. The purpose of the present research was to compare the isoflavone intake and blood lipids between hypertensive and normotensive and to examine dietary management for prevention of hypertension. Anthropometrical measurements, blood pressures, nutrients and isoflavone intakes using the 24-hour recall method, and serum lipids of 81 hypertensives and 77 normotensives were estimated. The average age, height, weight, and BMI were 58.2 years, l58.5 cm, 64.3 kg, and $25.6kg/m^2$ for the hypertensive and 58.0 years, 159.4 cm, 63.0 kg, and $24.8kg/m^2$ for the normotensive, respectively. Systolic and diastolic blood pressures of the hypertensive were significantly higher than those of the normotensive (p<0.001, p<0.001). The daily food intake of the hypertensive was significantly lower than that of the normotensive (p<0.01). The daily energy intakes of hypertensive and normotesive were 1479.8 kcal and 1590.9 kcal and there was no significant difference between the two groups. Carbohydrate intake of the hypertensive was significantly higher than that of the normotensive (p<0.05). However, daily intakes of plant protein, fiber, ash, calcium, sodium, potassium, and vitamin $B_1$ of the hypertensive were significantly lower than those of the normotensive (p<0.05, p<0.01, p<0.01, p<0.01, p<0.05, p<0.05, p<0.05). The daily intakes of daidzein, genistein, isoflavone of the hypertensive were significantly lower than those of the normotensive (p<0.05, p<0.05, p<0.05). However, isoflavone intakes per 1000 kcal showed no significant difference between the two groups. Serum lipids of the hypertensive and normotensive were l89.6 mg/dL and l87.2 mg/dL for total cholesterol, 157.3 mg/dL and 161.9 mg/dL for triglyceride, 42.9 mg/dL and 43.5 mg/dL for HDL-cholesterol, 115.2 mg/dL and 111.4 mg/dL for LDL-cholesterol, and 3.5 and 3.4 for atherogenic index. In the total subjects, there was a significantly negative correlation between systolic blood pressure and genistein intake (p<0.05). Based on these results, we concluded that the daily intakes of food, energy, and isoflavones of hypertensives were lower than normotensives. Therefore, it should be emphasized that proper dietary management considering these dietary factors for prevention of hypertension.

• Clinical and Experimental Pediatrics
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• 제63권8호
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• pp.321-328
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• 2020

Background: Pediatric hypertension is the main cause of morbidity and mortality in pediatric populations. Purpose: To examine pediatric hypertension in a clinical setting, we used the percentile rank approach and defined hypertension as that above the 95th percentile. Methods: The present study was linked to the a national analytical cross-sectional community-based Iranian Children and Adolescents' Psychiatric Disorders (IRCAP) survey. The survey was nationwide and funded by the National Institute of Medical Research Development. The IRCAP survey included 31,000 children and adolescents aged 6-18 years in all 31 Iran provinces. The current study included 1,035 children and adolescents and linked the data of the risk factors of cardiovascular disease only in Yazd province via random cluster sampling. Results: Of the total participants, 456 (44.1%) were male and 579 (55.9%) were female. The mean age was 11.2±3.8 years (11.7±3.7 years for males, 11.0±3.6 years for females), while mean height was 146±20.0 cm overall, 147.2±22.0 cm for males, and 144.6±17.0 cm for females (P=0.009). The blood pressure distributions and percentiles were evaluated. Conclusion: Here we determined age- and height-specific 50th, 90th, 95th, and 99th percentiles of systolic and diastolic blood pressures in Yazd boys and girls using 10-cm height intervals.