• Title/Summary/Keyword: Diagnostic value

Search Result 1,371, Processing Time 0.037 seconds

Two-Dimensional Shear Wave Elastography Predicts Liver Fibrosis in Jaundiced Infants with Suspected Biliary Atresia: A Prospective Study

  • Huadong Chen;Luyao Zhou;Bing Liao;Qinghua Cao;Hong Jiang;Wenying Zhou;Guotao Wang;Xiaoyan Xie
    • Korean Journal of Radiology
    • /
    • v.22 no.6
    • /
    • pp.959-969
    • /
    • 2021
  • Objective: This study aimed to evaluate the role of preoperative two-dimensional (2D) shear wave elastography (SWE) in assessing the stages of liver fibrosis in patients with suspected biliary atresia (BA) and compared its diagnostic performance with those of serum fibrosis biomarkers. Materials and Methods: This study was approved by the ethical committee, and written informed parental consent was obtained. Two hundred and sixteen patients were prospectively enrolled between January 2012 and October 2018. The 2D SWE measurements of 69 patients have been previously reported. 2D SWE measurements, serum fibrosis biomarkers, including fibrotic markers and biochemical test results, and liver histology parameters were obtained. 2D SWE values, serum biomarkers including, aspartate aminotransferase to platelet ratio index (APRi), and other serum fibrotic markers were correlated with the stages of liver fibrosis by METAVIR. Receiver operating characteristic (ROC) curves and area under the ROC (AUROC) curve analyses were used. Results: The correlation coefficient of 2D SWE value in correlation with the stages of liver fibrosis was 0.789 (p < 0.001). The cut-off values of 2D SWE were calculated as 9.1 kPa for F1, 11.6 kPa for F2, 13.0 kPa for F3, and 15.7 kPa for F4. The AUROCs of 2D SWE in the determination of the stages of liver fibrosis ranged from 0.869 to 0.941. The sensitivity and negative predictive value of 2D SWE in the diagnosis of ≥ F3 was 93.4% and 96.0%, respectively. The diagnostic performance of 2D SWE was superior to that of APRi and other serum fibrotic markers in predicting severe fibrosis and cirrhosis (all p < 0.005) and other serum biomarkers. Multivariate analysis showed that the 2D SWE value was the only statistically significant parameter for predicting liver fibrosis. Conclusion: 2D SWE is a more effective non-invasive tool for predicting the stage of liver fibrosis in patients with suspected BA, compared with serum fibrosis biomarkers.

The Comparative studies on Diagnostic Results of Yangdorack and EAV -on the 18 Cases of stroke patients- (양도락과 EAV 진단결과(診斷結果)에 대(對)한 상호비교(相互比較) 연구(硏究) -중풍(中風) 환자(患者) 18예(例)를 중심(中心)으로-)

  • Park Kyoung-Jin;Cho Myung-Rae;Yun Yeo-Chung
    • Journal of Acupuncture Research
    • /
    • v.15 no.2
    • /
    • pp.199-209
    • /
    • 1998
  • We compared and studied the results on two diagnostic machines called Yangdorack and EAV on 18 recovering paralytic patients. The results were as folIows ; 1. Patients with weak motor ability showed an average of 25% fewer units of Yangdorack and an average of 49% fewer units of EAV. 2. Deficiency/excess diagnostic results on meridian and internal organs showed 58.5% deficiency and 41.5% excess on the Yangdorack ; 67.9% of decline-degenerative activity and 32.1% of stimulus-inflarrunation activity on the EAV. 3. In the attack of meridian and internal organs in view of the five elements(五行), in rate of deficiency, decline and degeneration of the fire meridian(火經) in view of the highest rate accounts showed 19.5% on the Yangdorack and 20.4% on the EAV. 4. In comparing deficiency/excess results on the Yangdorack with results of decline-degenerative value and stimulus-inflammation value on the EAV, they both showes a 39% rate. 5. In comparing clinical syndromes on the Yangdorack and common diseases on the EAV, they showed a 72% agreement.

  • PDF

The Study on Quantum Efficiency of $CaWO_4$ Screen with Diagnostic X-ray (진단 X선에 대한 $CaWO_4$ 증감지의 양자효율 연구)

  • Park, Ji-Koon;Kang, Sang-Sik;Jang, Gi-Won;Lee, Hung-Won;Nam, Sang-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2002.11a
    • /
    • pp.379-382
    • /
    • 2002
  • Lately, intensifying screen of the $CaWO_4$ is used to medical treatment and diagnosis of the image. In this paper, we investigated transmission fraction and mass attenuation coefficient of $CaWO_4$ screen about diagnostic x-ray of low energy using MCNP 4C code. Experimentally, for 0.9 mm-$CaWO_4$ screen, the absorbable rate of diagnostic x-ray is more than 95%. according to kVp, the experimental value of mass attenuation coefficient is in a1most agreement with an corrected estimate value of MCNP and the deviation of experimental values is less than ${\pm}7%$. Using the MCNP code through this paper, we can make an estimate of signal and design for construction of the CaWO4/a-Se based digital x-ray image detector and make a good use of the foundation data for development of other materials.

  • PDF

Evaluation of Thermography in the Diagnosis of Carpal Tunnel Syndrome : Comparative Study between Patient and Control Groups

  • Hong, Yong-Pyo;Ryu, Kyeong-Sik;Cho, Byung-Moon;Oh, Sae-Moon;Park, Se-Hyuck
    • Journal of Korean Neurosurgical Society
    • /
    • v.39 no.6
    • /
    • pp.423-426
    • /
    • 2006
  • Objective : There is still debate about the diagnostic efficacy of digital infrared thermographic imaging[DITI], nevertheless, it has been used for the diagnosis of carpal tunnel syndrome[CTS]. We performed comparative study between patient and control groups to investigate the diagnostic value of DITI in CTS. Methods : We studied 27 patients with electrodiagnostically-proven CTS and 18 symptom-free volunteers as a control. We measured thermal difference on DITI in the corresponding regions of the hands and forearms. We statistically analyzed the thermal data using a t-test. Results : The average thermal difference in the diagnosed patient group ranged from $0.0303^{\circ}C$ to $0.2856^{\circ}C$, while that in control group ranged from $0.0611^{\circ}C$ to $0.2878^{\circ}C$. In the CTS patient group, thermal difference between each 2nd finger was higher than that of other regions. However, there was no statistical significance between patient and control groups. Conclusion : We found that the diagnostic value of DITI in CTS was not sufficient. There should be a reconsideration of the usefulness of DITI in CTS.

Diagnostic Validity of the Comprehensive Attention Test in Patients With Attention-Deficit/Hyperactivity Disorder

  • Hyunju Lee;Hannah Huh;Woo Young Kim;Eun Kyoung Lee;Bum-Sung Choi;Bongseog Kim;Hanik Yoo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • v.35 no.4
    • /
    • pp.243-249
    • /
    • 2024
  • Objectives: This study verified the diagnostic validity of the Comprehensive Attention Test (CAT) for attention-deficit/hyperactivity disorder (ADHD). Methods: A total of 336 participants were recruited in this study, including 168 patients with ADHD and 168 control group participants who were one-to-one matched for sex and age. We measured selective attention (visual and auditory), sustained attention, interference-selective attention, divided attention, and working memory in the ADHD and control groups using the CAT. The sensitivity, specificity, positive predictive value, and negative predictive value of the CAT were calculated. Results: In this study, it was found that the sensitivity and specificity of the CAT were 0.879 and 0.846 in children, 0.855 and 0.838 in adolescents, and 0.800 and 0.733 in adults, respectively. Conclusion: These results indicate that the CAT has a high diagnostic validity for ADHD from childhood to adulthood,

Oral Lichen Planus and Oral Lichenoid Lesion: Diagnosis and Assessment of Direct Immunofluorescence

  • Lee, Kyung-Eun
    • Journal of Oral Medicine and Pain
    • /
    • v.41 no.3
    • /
    • pp.91-98
    • /
    • 2016
  • Purpose: Oral lichen planus (OLP) has generated many discussions and been associated with much controversy for a long time. A reliable diagnosis of OLP has proven challenging and significant disagreements concerning its diagnosis has continued. Therefore, the aim of this study was to apprehend newly proposed diagnostic criteria of OLP and oral lichenoid lesion (OLL) and to evaluate difference of final diagnosis of OLP and OLL in accordance with type of diagnostic criteria. Also, direct immunofluorescence (DIF) was compared to evaluate the value of DIF between two groups. Methods: Fifty-two patients with DIF result were retrospectively reviewed. The selected patients were classified by the modified World Health Organization (WHO) diagnostic criteria of OLP and OLL and by criteria proposed by American Academy of Oral and Maxillofacial Pathology (AAOMP). Results of DIF in OLP and OLL were classified by deposition intensity or pattern of fibrinogen. The classification of fluorescence pattern in each specimen was graded as positive, possibly positive or negative. Results: Patients diagnosed as OLP were a few more when the modified WHO diagnostic criteria were used than when criteria proposed by AAOMP were used. There was no statistical difference of DIF between OLP and OLL by applying the WHO modification criteria or criteria proposed by AAOMP. Conclusions: The final diagnosis of OLP could be changed in accordance with type of diagnostic criteria and difference of DIF between OLP and OLL was not found.

Deterioration Diagnostic Techniques for Power Facilities by Analyzing Pulse-Height of leakage current (누설전류 파고분석에 의한 전력설비의 열화진단 기술)

  • 한주섭;김명진;손원진;길경석
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2001.10a
    • /
    • pp.367-370
    • /
    • 2001
  • This paper proposes a new deterioration diagnostic technique for power facilities by analyzing the pulse-height analysis of leakage current. Until now, various deterioration diagnostic techniques to prevent power system failures by deterioration of power facilities are suggested, and most of which measures leakage current amplitude only as a estimation parameter. In this experiment, it is known that the pulse heights of the leakage current are increased according to deterioration progress as well as there comes remarkable changes in pulse height distribution thereto. Therefore, the use of pulse height distribution in deterioration diagnostic technique makes more accurate diagnosis than the conventional method by using only leakage current value. From the application test, it is confirmed that the proposed technique has sufficient performance to diagnose deterioration of power facilities.

  • PDF

3D Segmentation of a Diagnostic Object in Ultrasound Images Using LoG Operator (초음파 영상에서 LoG 연산자를 이용한 진단 객체의 3차원 분할)

  • 정말남;곽종인;김상현;김남철
    • Journal of Biomedical Engineering Research
    • /
    • v.24 no.4
    • /
    • pp.247-257
    • /
    • 2003
  • This paper proposes a three-dimensional (3D) segmentation algorithm for extracting a diagnostic object from ultrasound images by using a LoG operator In the proposed algorithm, 2D cutting planes are first obtained by the equiangular revolution of a cross sectional Plane on a reference axis for a 3D volume data. In each 2D ultrasound image. a region of interest (ROI) box that is included tightly in a diagnostic object of interest is set. Inside the ROI box, a LoG operator, where the value of $\sigma$ is adaptively selected by the distance between reference points and the variance of the 2D image, extracts edges in the 2D image. In Post processing. regions of the edge image are found out by region filling, small regions in the region filled image are removed. and the contour image of the object is obtained by morphological opening finally. a 3D volume of the diagnostic object is rendered from the set of contour images obtained by post-processing. Experimental results for a tumor and gall bladder volume data show that the proposed method yields on average two times reduction in error rate over Krivanek's method when the results obtained manually are used as a reference data.

Development of Practical Investigation and Diagnosis Model in Rural Villages - Development of Empirical Diagnostic Indicators through Delphi Method - (농촌마을의 실증적 조사·진단기법 개발(I) - 델파이 설문조사를 통한 실증진단지표의 개발 -)

  • Koo, Hee-Dong;Park, Mi-Ran;Kim, Dae-Sik
    • Journal of Korean Society of Rural Planning
    • /
    • v.27 no.2
    • /
    • pp.91-104
    • /
    • 2021
  • The purpose of this study is to develop the diagnostic indices system that can be applied to the evaluation of rural village level, because the indicators developed in many existing studies were mostly consisted of statistical data in higher level than rural villages as well as those were difficult to apply to rural village level empirically. In order to develop the empirical diagnostic indices system, which has 52 indices with 7 categories, this study not only classified the kind of rural village facility and the regional development project of government, but also surveyed the specialist opinion with Delphi method. Especially, this study standardized the all diagnostic indices with positive value to remove the indices with negative values. Finally, the results that the study applied the empirical diagnostic indices to the 15 sample villages of Jinan-gun and Cheongyang-gun showed that there was the applicability of the indices system in the village level.

Diagnostic Value of Magnetic Motor Evoked Potential Parameters in Intramedullary Myelopathy (수내 척수병증에서 자기운동유발전위 지표의 진단적 가치)

  • Seo, Sang Hyeok;Kim, Yong Bum;Moon, Heui Soo;Chung, Pil Wook;An, Jae Young;Bae, Jong Seok;Kim, Minky;Shin, Kyong Jin;Kim, Byoung Joon
    • Annals of Clinical Neurophysiology
    • /
    • v.8 no.1
    • /
    • pp.29-35
    • /
    • 2006
  • Background: Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic method particularly suited to investigation the long motor tracts. The clinical value of TMS in most spinal cord diseases has still to be made. Diagnostic value of magnetic motor evoked potential (MEP) parameters in intramedullary spinal cord lesions was investigated. Methods: MEP elicited by TMS was recorded in 57 patients with clinically and radiologically defined intramedullary myelopathy. Twenty five patients with cervical myelopathy (CM) and 32 thoracic myelopathy (TM) were included. Recordings were performed during resting and minimal voluntary contraction at both abductor pollicis brevis (APB) and tibialis anterior (TA) muscles. Stimulation threshold(ST), amplitude, and central motor conduction time (CCT) were measured at resting and facilitated conditions. CCT was calculated by two means; central motor latency (CML)-M using magnetic transcranial and root stimulation, and CML-F using electrical F-wave study. The results were compared between patient groups and 10 normal control group. Results: Facilitated mean ST recorded at TA was elevated in both CM and TM compared with control group. Resting mean CML-M at TA was significantly prolonged in both CM and TM, and CML-M was absent or delayed in 37.1% of CM and 8% of TM at APB with facilitation. Facilitated mean MEP amplitude at ABP was lower in CM than in TM, while MEP/M ratios were not different significantly between groups. Conclusions: Magnetic motor evoked potential has diagnostic value in intramedullary myelopathy and localizing value in differentiating between CM and TM by recording at APB and TA. It is a noninvasive way to investigate the functional status of motor tracts of spinal cord.

  • PDF