• The Korean Journal of Cytopathology
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• v.15 no.1
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• pp.33-39
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• 2004

We compared the diagnostic accuracy of liquid-based cervicovaginal cytology using $MonoPrep2^{TM}$ system (Monogen, Herndon, Virginia, USA), a manual system based on membrane filtration method, with conventional Pap smear. Study population included 92 patients visiting the gynecologic department under the suspicion of uterine cervical disease. In thirty of them, surgical biopsy was performed. $MonoPrep2^{TM}$ system provided well-preserved monolayer specimen with good nuclear morphology. However, about 19% of specimens were inadequate to interpret due to low cellularity. The detection rate of abnormal cells more than ASCUS (atypical squamous cells of unknown significance) was 23.9% and higher than 19.4 % of conventional Pap smear. Diagnostic concordance rate with conventional Pap smear was 81%, and severe discordance rate influencing on the management of patient was 7.6 %. Among these seven cases, $MonoPrep2^{TM}$ system was more diagnostic only in four. In comparison with histology, the sensitivity of diagnosis of $MonoPrep2^{TM}$ system was 78.9% and slightly higher than 73.5% of conventional Pap smear. However, the specificity was 81.1% and lower than 90.9% of Pap smear. In conclusion, $MonoPrep2^{TM}$ system provided diagnostic accuracies similar to the conventional Pap smear. The inexpertness of slide preparation and the low cellularity were considered to endow a limitation in more accurate evaluation.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.97-102
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• 2013

Objective: The aim of this study was to develop an automated computer-aided diagnostic system for diagnosis of thyroid cancer pattern in fine needle aspiration cytology (FNAC) microscopic images with high degree of sensitivity and specificity using statistical texture features and a Support Vector Machine classifier (SVM). Materials and Methods: A training set of 40 benign and 40 malignant FNAC images and a testing set of 10 benign and 20 malignant FNAC images were used to perform the diagnosis of thyroid cancer. Initially, segmentation of region of interest (ROI) was performed by region-based morphology segmentation. The developed diagnostic system utilized statistical texture features derived from the segmented images using a Gabor filter bank at various wavelengths and angles. Finally, the SVM was used as a machine learning algorithm to identify benign and malignant states of thyroid nodules. Results: The SVMachieved a diagnostic accuracy of 96.7% with sensitivity and specificity of 95% and 100%, respectively, at a wavelength of 4 and an angle of 45. Conclusion: The results show that the diagnosis of thyroid cancer in FNAC images can be effectively performed using statistical texture information derived with Gabor filters in association with an SVM.

• Journal of Aerospace System Engineering
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• v.11 no.1
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• pp.35-40
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• 2017

Aircraft diagnostic systems identify system failures and nip aircraft accidents in the bud by removing hazards that hinder Safety Of Flight (SOF). The necessity for diagnostic systems is increasing as aircraft manufacturing technology is modernized. Many countries have conducted studies and developed diagnostic systems. However, studies about diagnostic systems are very few in Korea. This study defines the scope of aircraft diagnostics systems and closely considers methods to ensure the Safety Of Flight (SOF) for military aircraft.

• The Journal of the Acoustical Society of Korea
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• v.29 no.6
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• pp.355-364
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• 2010

Considering biological safety, it is very important to measure acoustic power from ultrasonic array probe for diagnostic ultrasound imaging applications. In this paper, to measure acoustic power from each element on array probe for ultrasonic diagnostic equipment, we reconstruct and automate the acoustic power measurement system. The acoustic power from linear, phased and curved array were measured and analyzed. As a result of measurement, the effects caused by directivity of sound beam from curved array were founded. To remove these effects, we developed and applied the correction model. The proposed system is useful to evaluate characteristics of the acoustical output power of array probe.

• Korean Journal of Radiology
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• v.21 no.11
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• pp.1210-1219
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• 2020

Objective: To compare the utility and diagnostic performance of automated breast ultrasound system (ABUS) with that of handheld ultrasound (HHUS) in evaluating pure non-mass enhancement (NME) lesions on breast magnetic resonance imaging (MRI). Materials and Methods: One hundred twenty-six consecutive MRI-visible pure NME lesions of 122 patients with breast cancer were assessed from April 2016 to March 2017. Two radiologists reviewed the preoperative breast MRI, ABUS, and HHUS images along with mammography (MG) findings. The NME correlation rate and diagnostic performance of ABUS were compared with that of HHUS, and the imaging features associated with ABUS visibility were analyzed. Results: Among 126 pure NME lesions, 100 (79.4%) were malignant and 26 (20.6%) were benign. The overall correlation rate was 87.3% (110/126) in ABUS and 92.9% (117/126) in HHUS. The sensitivity and specificity were 87% and 50% for ABUS and 92% and 42.3% for HHUS, respectively, with no significant differences (p = 0.180 and 0.727, respectively). Malignant NME was more frequently visualized than benign NME lesions on ABUS (93% vs. 65.4%, p = 0.001). Significant factors associated with the visibility of ABUS were the size of NME lesions on MRI (p < 0.001), their distribution pattern (p < 0.001), and microcalcifications on MG (p = 0.027). Conclusion: ABUS evaluation of pure NME lesions on MRI in patients with breast cancer is a useful technique with high visibility, especially in malignant lesions. The diagnostic performance of ABUS was comparable with that of conventional HHUS in evaluating NME lesions.

• Journal of the Korean Data and Information Science Society
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• v.8 no.2
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• pp.173-181
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• 1997

In oriental medicine, it is required that correct medical knowledge should be maintained for medical expert system which analyzes and diagnoses patients symptoms. Typical medical expert system has a knowledge base as its core, and the knowledge base contains a domain specific knowledge about patients records. However, oriental medicine diagnostic knowledge is formed mostly as qualitative data, knowledge could be ambiguous and uncertain. In this paper, we looked at quantification methods and propose a method for quantifying the oriental medicine diagnostic knowledge, which is improving the knowledge base of an oriental medicine expert system.

• Membrane Journal
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• v.17 no.1
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• pp.31-36
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• 2007

Polyurethane diagnostic membranes were prepared to measure blood glucose level of diabetics. Final absorbances at 680 nm through activated polyurethane membranes were measured at various concentration of glucose in plasma or blood. The effects of storage temperatures on the measurements of glucose concentration were studied after storage of 3 days, 1 week, 3 weeks, and 5 weeks at various temperatures. The stabilities of polyurethane diagnostic membranes were examined at RH 80%.

• 대한상한금궤의학회지
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• v.7 no.1
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• pp.127-132
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• 2015

Objectives: The purpose of this case is to report the effects of Baekho-tang based on Shanghanlun disease pattern identification diagnostic system. Methods : According to diagnostic system based on Shanghanlun provisions, the patient was diagnosed as Gwoleum-byung(厥陰病). Visual analogue scale was used to check the symptoms while the patient taking herbal medicine Baekho-tang for 12 weeks. Results : After taking Baekho-tang, Visual analogue scale in hot flashes markedly decreased 9 to 1. Conclusions : This paper shows an efficient result of using Baekho-tang based on Shanghanlun disease pattern identification diagnostic system. Further studies should be needed to validate the effects of Baekho-tang.

• 대한상한금궤의학회지
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• v.7 no.1
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• pp.107-113
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• 2015

Objective : This study aims to explain the effect of Buja-tang on Postherpetic Neuralgia with Chronic Fatigue Syndrome which a Soeum-byeong patient has. Methods : This is a case report on a female patient who has been suffering from Postherpetic Neuralgia with Chronic Fatigue Syndrome. According to Diagnostic system based on Shanghanlun provisions, Buja-tang was provided for one month. Results : After a series of Buja-tang treatments, the patient's symptoms and result improved. Conclusions : This case study show an effectiveness of using Buja-tang according to Diagnostic system based on Shanghanlun provisions on Postherpetic Neuralgia with Chronic Fatigue Syndrome.

• 대한상한금궤의학회지
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• v.7 no.1
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• pp.45-52
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• 2015

Objective : This case report aims to demonstrate the effect of Oryeong-san on Insomnia. Methods : A 26 year old woman suffered from insomnia with mental and physical exhaustion, reduced stamina, lack of concentration in daytime. According to Diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Taeyang-byung and treated by Oryeong-san decoction. The result of administration was evaluated by Insomnia Severity Index. Results : After administration of Oryeong-san decoction for 1 month, Insomnia Severity Index was decreased from 24(clinical insomnia, severe) to 1(no clinically significant insomnia). Conclusions : The patient completely recovered from insomnia and daytime symptoms as treated by Oryeong-san decoction according to Diagnostic system based on Shanghanlun provisions.