• 제목/요약/키워드: Diagnostic study

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미병(未病)의 의학적 개념 정립을 위해 고려해야 할 주제들 (Medical issues to consider for establishing the concept of Mibyeong)

  • 남동현;한경숙
    • 대한한의진단학회지
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    • 제24권1호
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    • pp.1-13
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    • 2020
  • Objectives Mibyeong is an ideological concept that means the state between the healthy and diseased conditions. The purpose of this study was to suggest a research direction to establish the diagnostic criteria for the Mibyeong by reviewing the research results for the Mibyeong. Methods Academic databases (OASIS for Korean database, Embase for English database, and CNKI for Chinese database) were used to search related literatures, and articles describing the concept or diagnostic criteria of the disease were selected. Results The concept of Mibyeong consisted of three different conditions: (1) subjective symptoms without a specific disease, (2) abnormal examination findings without a specific disease, and (3) a state in between health and disease. No matter which of the three conditions is applied, the spectrum of condition was very wide and diverse. Conclusions It is impossible to apply appropriate and monolithic diagnostic criteria to all types of Mibyeong. Therefore, we suggests that the Mibyeong be classified into several subtypes and the diagnostic criteria suitable for each type be established.

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어린이집 자율관리를 위한 조직역량 진단도구(S.T.E.P+)의 개발 및 타당화 (Development and Validation of S.T.E.P+ Diagnostic Tool: Assessing Organizational Competence for Self-management in Daycare Centers)

  • 강정원;박소영;이원선;임여정
    • 한국보육지원학회지
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    • 제20권2호
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    • pp.105-126
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    • 2024
  • Objective: The study aimed to develop and validate a tool for assessing daycare center organizational competence and for autonomously managing childcare quality. Methods: Through literature review and expert reviews, items were derived and validated using the Content Validity Index. Data from a survey involving 216 directors and 509 teachers were analyzed using SPSS and AMOS to assess reliability and conduct confirmatory factor analysis. Results: Results revealed a 36-item diagnostic tool across four subcategories: shared values (6 items), training abilities (18 items), environmental support (6 items), and organizational promotion (6 items). A diagnostic tool named S.T.E.P+ was developed, named after the first letters of the four subfactors. Skewness and kurtosis were within normality assumptions. Good fit indices (CFI, TLI) and low SRMR and RMSEA values indicated a satisfactory model fit. Cronbach's α values showed high reliability for all factors. The tool enables autonomous diagnosis of childcare quality. Conclusion/Implications: This tool can effectively autonomously diagnose whether a daycare center is providing quality childcare.

Development of Standardized Predictive Models for Traditional Korean Medical Diagnostic Pattern Identification in Stroke Subjects: A Hospital-based Multi-center Trial

  • Jung, Woo-Sang;Cho, Seung-Yeon;Park, Seong-Uk;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho;Kwon, Seungwon
    • 대한한의학회지
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    • 제40권4호
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    • pp.49-60
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    • 2019
  • Objectives: To develop a standardized diagnostic pattern identification equation for stroke patients, our group conducted a study to derive the predictive logistic equations. However, the sample size was relatively small. In the current study, we aimed to derive new predictive logistic equations for each diagnostic pattern using an expanded number of subjects. Methods: This study was a hospital-based multi-center trial recruited stroke patients within 30 days of symptom onset. Patients' general information, and the variables related to diagnostic pattern identification were measured. The diagnostic pattern of each patient was identified independently by two Korean Medicine Doctors. To derive a predictive model for pattern identification, binary logistic regression analysis was applied. Results: Among the 1,251 patients, 385 patients (30.8%) had the Fire Heat Pattern, 460 patients (36.8%) the Phlegm Dampness Pattern, 212 patients (16.9%) the Qi Deficiency Pattern, and 194 patients (15.5%) the Yin Deficiency Pattern. After the regression analysis, the predictive logistic equations for each pattern were determined. Conclusion: The predictive equations for Fire Heat, Phlegm Dampness, Qi Deficiency, and Yin Deficiency would be useful to determine individual stroke patients' pattern identification in the clinical setting. However, further studies using objective measurements are necessary to validate these data.

Critical Evaluation of Fine Needle Aspiration Cytology as a Diagnostic Technique in Bone Tumors and Tumor-like Lesions

  • Chakrabarti, Sudipta;Datta, Alok Sobhan;Hira, Michael
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권7호
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    • pp.3031-3035
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    • 2012
  • Background: Though open surgical biopsy is the procedure of choice for the diagnosis of bone tumors, many disadvantages are associated with this approach. The present study was undertaken to evaluate the role of fine needle aspiration cytology (FNAC) as a diagnostic tool in cases of bony tumors and tumor-like lesions which may be conducted in centers where facilities for surgical biopsies are inadequate. Methods: The study population consisted of 51 cases presenting with a skeletal mass. After clinical evaluation, radiological correlation was done to assess the nature and extent of each lesion. Fine needle aspiration was performed aseptically and smears were prepared. Patients subsequently underwent open surgical biopsy and tissue samples were obtained for histopathological examination. Standard statistical methods were applied for analysis of data. Results: Adequate material was not obtained even after repeated aspiration in seven cases, six of which were benign. Among the remaining 44 cases, diagnosis of malignancy was correctly provided in 28 (93.3%) out of 30 cases and categorical diagnosis in 20 (66.67%). Interpretation of cytology was more difficult in cases of benign and tumor-like lesions, with a categorical opinion only possible in seven (50%) cases. Statistical analysis showed FNAC with malignant tumors to have high sensitivity (93.3%), specificity (92.9%) and positive predictive value of 96.6%, whereas the negative predictive value was 86.7%. Conclusion: FNAC should be included in the diagnostic workup of a skeletal tumor because of its simplicity and reliability. However, a definitive pathologic diagnosis heavily depends on compatible clinical and radiologic features which can only be accomplished by teamwork. The cytological technique applied in this study could detect many bone tumors and tumor-like conditions and appears particularly suitable as a diagnostic technique for rural regions of India as other developing countries.

온라인 진단시스템에 사용되는 의사용 체질진단함수의 진단정확률 연구 (A Study on the Diagnostic Accuracy Rate of the Sasang Constitution Questionnaire for Doctors Used in the On-line System)

  • 전수형;정성일;권석동;박세정;김규곤;김종원
    • 사상체질의학회지
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    • 제20권3호
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    • pp.82-93
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    • 2008
  • 1. Objective The purpose of this study was to develop and upgrade the On-line SSCQ (Sasang Constitution Questionnaire) by making an analysis of diagnostic accuracy rate of Sasang Constitution Questionnaire for doctors. 2. Methods We have collected SSCQ-D(Sasang Constitution Questionnaire for Doctors) from the dept. of Sasang constitutional medicine in the four other university. We classified data according to Sasang constitution, sex, age and BMI and made an analysis using the chiefly discriminant analysis model, additionally frequency analysis, and Cronbach's alpha coefficient. 3. Results and Conclusion 1) Diagnostic accuracy rate of the SSCQ-D was between 71.33 and 95.14%. (1) About the whole subject the accuracy rate was 71.33%. (2) About the whole female the accuracy rate was 73.26%. (3) About the whole male the accuracy rate was 81.41%. 2) The more classification variables we used in this analysis study, the higher the diagnostic accuracy rate increased.

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산후풍 진단 기준 개정 위한 델파이조사 결과 (A Delphi Survey for the Revision of the Diagnostic Criteria for Sanhupung (Puerperal Wind Disorder, U32.7))

  • 최수지;김동일
    • 대한한방부인과학회지
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    • 제35권2호
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    • pp.42-53
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    • 2022
  • Objectives: The definition of Sanhupung (Puerperal wind disorder) has been varied and there has been a prior study to establish the definition, but no clear conclusion has been reached on diagnostic criteria. Therefore, the aim of this study was to clearly redefine the definition of Sanhupung using the Delphi method. Methods: This study used the Delphi technique. A panel consisting of 13 experts of Korean medicine, particularly in Obstetrics & Gynecology, participated in the Delphi survey that included answering the 3rd round survey. The Delphi survey was conducted by evaluating and correcting the questionnaire using e-mail. Results: Through the Delphi survey, we have reached an agreement regarding the diagnostic criteria of Sanhupung. They are as follows: 1) Sanhupung can be diagnosed based on basic symptoms. If one or more symptoms are expressed in the basic symptom group, it can be diagnosed as Sanhupung. It is diagnosed in detail as a pain type or a sensory impairment type according to the category of basic symptoms. 2) Incidental symptoms are not essential for diagnosis, and are referred to for checking general weakness and autonomic nervous system conditions. 3) In order to meet the diagnostic criteria, the symptoms should occur within 6 months after childbirth or miscarriage, and the cause of the symptoms should not be classified as other diseases. Conclusions: The diagnostic criteria of Sanhupung were suggested based on the Delphi survey among experts in the field. Further research is necessary to improve the reliability and validity of the criteria.

Molecular subtyping and antimicrobial susceptibility of Streptococcus dysgalactiae subspecies equisimilis isolates from clinically diseased pigs

  • Oh, Sang-Ik;Kim, Jong Wan;Kim, Jongho;So, Byungjae;Kim, Bumseok;Kim, Ha-Young
    • Journal of Veterinary Science
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    • 제21권4호
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    • pp.57.1-57.11
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    • 2020
  • Background: Streptococcus dysgalactiae subspecies equisimilis (SDSE) acts as an etiological agent for lameness, neurological signs, and high mortality in pigs. Despite its importance in pig industries and zoonotic potential, little is known about the effects of this pathogen. Objectives: This study aimed to determine the molecular characteristics and antimicrobial resistance of SDSE strains isolated from diseased pigs. Methods: A total 11 SDSE isolates were obtained from diseased pigs. Bacterial identification, PCR for virulence genes, emm typing, and antimicrobial resistance genes, multilocus sequence typing, and antimicrobial susceptibility test were performed. Results: Nine isolates were from piglets, and 8 showed lameness, sudden death, or neurological signs. The isolates were PCR-positive for sla (100%), sagA (100%), and scpA (45.5%), and only 1 isolate amplified the emm gene (stL2764). Eight different sequence types were detected, categorized into 2 clonal complexes and 4 singletons. All the isolates in this study were included in a small cluster, which also contained other strains derived from humans and horses. The minimum inhibitory concentrations for the tested beta-lactams were low, while those for macrolides, tetracyclines, and fluoroquinolones were relatively high. PCR analysis of the macrolide and tetracycline resistance genes demonstrated that the isolates carried erm(B) (18.2%, n = 2), mef(A/E) (9.1%, n = 1), tet(M) (18.2%, n = 2), and tet(O) (90.2%, n = 10). Two isolates presented a mutation in parC, which is associated with fluoroquinolone resistance. Conclusion: This study provided insight into swine-derived SDSE, as it is related to veterinary medicine, and elucidated its zoonotic potential, in the context of molecular epidemiology and antimicrobial resistance in public health.

단순 방사선 영상기반 바이오마커를 활용한 흉·요추의 추나의학적 변위 진단 방법 (Radiograph-based Diagnostic Methods for Thoracic and Lumbar Spine Malposition in Chuna Manual Therapy Using Biomarkers)

  • 이진현;최민호;김중일;장준수;박태용
    • 척추신경추나의학회지
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    • 제18권2호
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    • pp.1-8
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    • 2023
  • Objectives This study aimed to propose biomarkers for diagnosing Chuna manual therapy (CMT) based on X-ray images in the thoracic and lumbar spines. Methods Through a literature review and expert consensus process, diagnostic biomarkers for CMT were selected based on the listing system in thoracic and lumbar radiograph anterior-posterior (AP) and lateral views. Results 1. Diagnostic biomarkers were derived from four points on the outer contour of the vertebral body in the thoracic and lumbar spine radiograph lateral view, enabling the diagnosis of flexion and extension malposition. 2. Additional diagnostic biomarkers were identified in the thoracic and lumbar radiographAP view, utilizing points on the outer contour of the vertebral body. These biomarkers facilitate the diagnosis of lateral bending. Moreover, biomarkers derived from the innermost point of the pedicle contour allow for the diagnosis of rotation malposition. 3. Furthermore, through the biomarkers proposed in this study, all malpositions of the thoracolumbar spines and complex Type I and II malpositions can be diagnosed in CMT. Conclusions The biomarkers reported in this study consist of minimal points to determine the position of the vertebral body, providing the advantage of simplicity while minimizing potential errors during the CMT diagnostic process. Further clinical research and the development of related programs should be pursued to expand the evidence for CMT.

담적의 진단요소 및 증후군으로서의 가치에 대한 문헌고찰 (A Literature Study on the Diagnostic Factors and Value as a Syndrome of Damjeok)

  • 임윤서;노기환;최규호;이상현;최서형
    • 대한한의학회지
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    • 제44권3호
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    • pp.170-188
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    • 2023
  • Objectives: The purpose of this study is to investigate the diagnostic factors of Damjeok in the literature. Methods: This study used the databases of five (Mediclassics, RISS, KMbase, OASIS, CNKI) to analyze diagnostic factors of Damjeok. Literatures published by May 2023 were assessed and we classified 91 literatures dealing with diagnostic factors by 5 categories, 'characteristics', 'location', 'symptom', 'pulse wave & tongue feature', and 'eating habits & lifestyle'. Results: Damjeok is mainly formed at the stomach in the form of lump or hard seed, and it can be observed in other regions or even the whole body by its trait of floating. Damjeok mainly shows symptoms of the digestive system and also causes various symptoms associated with the respiratory system and infection, musculoskeletal system, urogenital system, neuropsychiatric system and cardiovascular system. Regarding pulse wave and tongue feature, a slippery wave and greasy coated tongue are typical features of Damjeok. Additionally, bad eating habits and a lack of exercise have been described as a factor that cause and aggravate Damjeok. Conclusions: The two most important factors in the diagnosis of Damjeok are abdominal stiffness by physical examination and digestive symptoms, and these correspond to the definition of a syndrome. Diagnostic factors based on literature evidence will provide clues to the clinical diagnosis of Damjeok syndrome.

맥진기(脈診器)를 이용한 아토피 피부염 환자의 임상적 고찰 (A clinical study of atopic dermatitis patients as measured by Pulse diagnostic apparatus)

  • 신윤진;김윤범;윤상협
    • 한방안이비인후피부과학회지
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    • 제21권2호
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    • pp.112-119
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    • 2008
  • Objective : The quantification of pulse diagnosis is an important subject utilizing as a modernization of Oriental medical diagnosis and as a basic data for collaborative access between East and West Medicine. This study was to observe the tendency of pulse diagnosis in atopic dermatitis patients as measured by pulse diagnostic apparatus. Methods : We did pulse diagnostic test about 11 new outpatients who had visited the department of ophthalmology, otolaryngology, dermatology in Kyunghee oriental medical center from March 1, 2007 to October 31, 2007 and had atopic dermatitis. Results : The results were as follows. 1. Among the 11 outpatients, the total number of male patients were 5 and female patients were 6, and the age distribution, the most frequently visited age groups were 10-19 years old and 20-29 years old(each 4 patients). 2. The most common period of onset to first examination were 3 years${\leq}$ (7 patients). 3. There were 8 patients who had emphasized T-wave. 4. There were 7 patients who had repeated pulse wave pattern. Conclusion : In 11 cases who had atopic dermatitis, 8 patients had emphasized T-wave and 7 patients had repeated pulse wave pattern.

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