• The Journal of Korean Physical Therapy
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• v.35 no.3
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• pp.57-63
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• 2023

Purpose: The aim of this study was to conduct a systematic review of randomized controlled studies from 2012 to present that explore the diagnostic accuracy of clinical tests used for diagnosing anterior cruciate ligament (ACL) injury. Methods: Study design: Systematic review. Literature search of the PubMed and Scholar databases was conducted using keywords related to diagnostic accuracy of clinical tests for ACL injury. The PRISMA Guidelines were followed to conduct this study. The Cochrane Risk of Bias Tool was utilized to assess the quality of each included study. Results: As a result, 8 studies were included, and 6 clinical tests used in ACL tears were evaluated for diagnostic accuracy. The pivot shift test was reported as having the highest +LR (29.5) value with a sensitivity of 59% and a specificity of 98%. However, the test with the lowest -LR value was the lever test, and the values were as follows: -LR (0.08), +LR (4.7), specificity (80%), sensitivity (94%). Conclusion: In this study, it was concluded that a single clinical test is not sufficient to determine the presence of ACL injury. Test combinations have a higher diagnostic accuracy than a single test. In this study, the accuracy of the clinical tests was examined without considering the amount of ACL rupture and acute-chronic condition. Further research is required to examine the impact of these two factors on diagnostic accuracy of clinical test.

• Korean Journal of Radiology
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• v.20 no.1
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• pp.158-165
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• 2019

Objective: Recent studies demonstrated that core needle biopsy (CNB) can effectively reduce the possibility of inconclusive results and prevent unnecessary diagnostic surgery. However, the effectiveness of CNB in patients with suspicious thyroid nodules has not been fully evaluated. This prospective study aimed to determine the potential of CNB to assess thyroid nodules with suspicious ultrasound (US) features. Materials and Methods: Patients undergoing CNB for thyroid nodules with suspicious features on US were enrolled between May and August 2016. Diagnostic performance and the incidence of non-diagnostic results, inconclusive results, conclusive results, malignancy, unnecessary surgery, and complications were analyzed. Subgroup analysis according to nodule size was performed. The risk factors associated with inconclusive results were evaluated using multivariate logistic regression analysis. Results: A total of 93 patients (102 thyroid nodules) were evaluated. All samples obtained from CNB were adequate for diagnosis. Inconclusive results were seen in 12.7% of cases. The diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value for diagnosis of malignancy were 93.8%, 100%, 100%, 78.9%, and 95%, respectively. None of the patients underwent unnecessary surgery. The diagnostic performance was not significantly different according to nodule size. On multivariate logistic regression analysis, larger nodule size and shorter needle length were independent risk factors associated with inconclusive results. Conclusion: Samples obtained by CNB were sufficient for diagnosis in all cases and resulted in high diagnostic values and conclusive results in the evaluation of suspicious thyroid nodules. These findings indicated that CNB is a promising diagnostic tool for suspicious thyroid nodules.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.28 no.3
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• pp.74-83
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• 2020

Securing excellent pilots is not only directly linked to the military's improved combat capabilities, but also a way to minimize human and property losses from aircraft accidents. Therefore, a scientific method is needed to diagnose pilot aptitude from the pilot selection process and select those with high accident potential, those who are dropped out of the flight training process, and those who are not suitable for pilot life in advance. Developed countries have implemented pilot aptitude tests to solve these problems early on, but so far, the Korean Army has not introduced a pilot aptitude test system that uses diagnostic tools in the helicopter pilot selection process. Therefore, in this study, scientific diagnostic tools are developed for selecting helicopter pilots, and through this, it is predicted that the number of people who are likely to be dropped out of the training course and who have the potential for accidents will be selected in advance and eliminated in the selection process. In this context, prior research examined the key factors involved in the pilot aptitude test. Through this, the aptitude test items were developed and aptitude tests were conducted on student pilots currently in flight training, and the results of flight training were analyzed.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.18 no.2
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• pp.63-74
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• 2014

Objectives The purpose of this study was to survey the current status of use of questionnaires for evaluating Yin Deficiency Syndrome and analyze the comparison with questionnaires. Methods We searched online medical databases to find domestic/international articles using questionnaires for evaluating intensity of Yin Deficiency Syndrome. Finally 18 articles were collected to be reviewed and they were classified according to their subjects and type of the Questionnaires. Results Out of 18 articles, 11 were based on the Yin-Deficiency Questionnaire (Yin-DQ) and the others used various questionnaires, except the Yin-DQ, for assessing Yin Deficiency Syndrome. In Korea the Yin-DQ was used widely but in foreign countries, for instance, China, Taiwan, a variety of questionnaires were used. Conclusion The Yin-DQ had a wider use in assessing Yin Deficiency Syndrome, but cut-off score for diagnostic criteria was not defined. Therefore, we decided that the YDS (Yin Deficiency Scale) with cut-off score was more suitable for screening patients with Yin Deficiency Syndrome. Moreover, we suggested that additional studies on using the YDS and developing more appropriate diagnostic tool should be conducted to improve diagnostic objectivity.

• Korean Journal of Veterinary Research
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• v.48 no.3
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• pp.357-361
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• 2008

Although power analysis is of important tool of research, investigators in veterinary medicine are unaware of the concepts of the statistical power. Two types of error occur in classical hypothesis testing and, those errors should be avoided, if possible. Since power is highly dependent on the sample size, whenever declaring non-statistically significant result they should consider the potential for committing a Type II error in their studies, which refers to the probability of falsely stating that two treatments are equivalent despite true difference between them. Also, sample size determination is one of the most important tasks facing the researcher when planning a diagnostic study, and provides valuable information on the characteristics of a test performance. This type of analysis forms the basis for proper interpretation of test results. The aim of this article was to re-evaluate some selected studies on diagnostic test reported in the domestic veterinary publications to determine the power and necessary sample size for inequality testing to ensure the desired power. Power calculations were illustrated using real-life examples of comparison of a new test and a reference test for detecting antibodies of various animal diseases. Factors affecting to the power were also discussed.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.4
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• pp.554-559
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• 2004

The objective of the present study was to investigate the accuracy of mastitis diagnostic indicators for different dairy goat breeds. Biweekly milk samples were collected from individual half mammary gland of seven Saanen and seven Alpine dairy goats in the period of 40 to 120 days in milk. With threshold value set at 2.8 and 3.1 for Alpine and Saanen dairy goats, respectively, log (SPC) offered good sensitivity (0.89, 0.93), specificity (0.88, 0.95), positive predictive value (0.75, 0.85) and negative predictive value (0.95, 0.98) as a mastitis diagnostic tool. The correlations of log (SPC) with milk yield, log (SCC), ALP, LDH, $Na^{+}$, $K^{+}$ and EC were significant in Saanen dairy goats (p<0.05), with the highest correlation coefficient (0.653) existing between log (SPC) and log (SCC). The correlations of log (SPC) with milk yield, milk fat, milk protein, log (SCC), $Na^{+}$, $K^{+}$, EC were significant in Alpine dairy goats (p<0.05), with the highest correlation coefficient (0.416) existing between log (SPC) and log (SCC). There were different best-fit regression equations with different multiple diagnostic indicators for Saanen and Alpine dairy goats. In conclusion, different breeds of dairy goats may have to adapt different mastitis diagnostic parameters for a better diagnosis.

• Journal of fish pathology
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• v.37 no.1
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• pp.89-96
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• 2024

Kudoa septempunctata, a myxozoan parasite, usually presents without any signs and primarily infects adult fish. The invasive diagnostic methods, such as tissue biopsy, can identify pathogens, but cause economic losses because they require killing the fish. In this study, we conducted a monitoring of four fish farms located on Jeju Island, to investigate the potential for non-invasive diagnosis of K. septempunctata using hyperspectral cameras. It provides spectral information from R000_B000_G000 to R255_B255_G255 for a total of 3,282 olive flounder (Paralichthys olivaceus). Each object is imaged with 2,000 data points, allowing comprehensive spectral analysis by comparing images obtained from negative control objects to positive control objects. Noticeable differences were observed in the brightness or pallor of the positive control images. This suggests the potential utility of hyperspectral imaging as a non-invasive diagnostic tool for detecting K. septempunctata infections in fish populations.

• Tuberculosis and Respiratory Diseases
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• v.87 no.1
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• pp.91-99
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• 2024

Background: Tuberculous pleural effusion (TPE) and parapneumonic effusion (PPE) are often difficult to differentiate owing to the overlapping clinical features. Observational studies demonstrate that the ratio of lactate dehydrogenase to adenosine deaminase (LDH/ADA) is lower in TPE compared to PPE, but integrated analysis is warranted. Methods: We conducted a systematic review to evaluate the diagnostic accuracy of the LDH/ADA ratio in differentiating TPE and PPE. We explored the PubMed and Scopus databases for studies evaluating the LDH/ADA ratio in differentiating TPE and PPE. Results: From a yield of 110 studies, five were included for systematic review. The cutoff value for the LDH/ADA ratio in TPE ranged from <14.2 to <25. The studies demonstrated high heterogeneity, precluding meta-analysis. Quality Assessment of Diagnostic Accuracy Studies Tool 2 assessment revealed a high risk of bias in terms of patient selection and index test. Conclusion: LDH/ADA ratio is a potentially useful parameter to differentiate between TPE and PPE. Based on the limited data, we recommend an LDH/ADA ratio cutoff value of <15 in differentiating TPE and PPE. However, more rigorous studies are needed to further validate this recommendation.

• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.357-358
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• 2009

• Communications for Statistical Applications and Methods
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• v.7 no.2
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• pp.403-414
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• 2000

A diagnostic tool for testing homogeneity for random effects is proposed in unbalanced linear mixed model based on score statistic. The finite sample behavior of the test statistic is examined using Monte Carlo experiments examine the chi-square approximation of the test statistic under the null hypothesis.