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Central nervous system depressant activity of Leucas aspera root

  • Rahman Shafiur;Sarder Mokaddez;Ali Yusuf;Rashid Abdur
    • Advances in Traditional Medicine
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    • v.6 no.3
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    • pp.174-178
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    • 2006
  • The ethanolic extract of Leucas aspera root was studied for its effect on the central nervous system (CNS) using pentobarbitone induced sleeping time test, the open field test and the hole cross test in Swiss albino mice. The present investigation revealed that the extract at the doses of 250 and 500 mg/kg, significantly prolonged the pentobarbitone induced sleeping time in mice though the onset of sleep was delayed as compared to control. In open field test the depressing effect was prominent from the second observation period (30 min) and persisted throughout the entire experimental period (240 min). In the hole cross test, the depressing effect was observed significant from the third observation period (60 min) and persisted up to the seventh observation period (240 min) except at fourth observation (90 min) for 250 mg dose group and depressing effect was significant from second observation (30 min) up to seventh observation period (240 min) for 500 mg dose group. These results support the finding that Leucas aspera root may contain biologically active constituent(s) having CNS activity.

Human exposure of hazardous elements from different urban soils in Bangladesh

  • Islam, Md.S.;Ahmed, Md.K.;Al-Mamun, Md.H.
    • Advances in environmental research
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    • v.5 no.2
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    • pp.79-94
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    • 2016
  • In order to evaluate the contamination and health risk, levels of six hazardous elements i.e., Cr, Ni, Cu, As, Cd and Pb in soils of 12 different land-uses were measured. The average concentration of Cu, Cr, Ni, Pb, As and Cd in soils were 267, 239, 206, 195, 58 and 16 mg/kg, respectively. Levels of each metal exceeded the environmental action level for soils, which could pose significant risk to human. The metal concentrations were subsequently used to establish hazard indices (for adults and children) where the 5th and 95th percentile values were used to derive the hazard index through different exposure pathways (ingestion, dermal contact and inhalation). Considering the total exposure through each of the three pathways, the hazard index elucidates that there was a potency of non-cancer risk at most of the sites for both the adults and children. The findings of this study suggested that different land-use soils were severely contaminated with hazardous elements and attention is needed on the potential health risks to the exposed inhabitants.

Importance of Annual Report to the Shareholders: Empirical Evidence from Bangladesh

  • Khatun, Naima;Naima, Jannatul;Karim, Ziaul;Alam, Lamia
    • The Journal of Asian Finance, Economics and Business
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    • v.3 no.3
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    • pp.67-77
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    • 2016
  • Shareholders solely depend on annual reports to make investment, credit and other decisions. Investors expect that information should be reliable, relevant, comparable, consistent and thus easy to use for decision making. But whether the importance of annual reports to all shareholders is equally significant is a question of research. Thus, this research study tries to find out the importance of reading annual reports to the investors. A questionnaire survey is conducted on investors considering thirty one general shareholders and six brokers. This research based survey finds that most of the shareholders have no knowledge about accounting or finance and they have little knowledge about capital markets due to lack of training. This study also finds that general shareholders read an annual report at least moderately except value added statement, chairman's review, director's report and rumor. This study recommends human resource should be developed through adequate training, and annual reports should provide transparent and quality information which will ultimately increase the confidence of investors.

Top-executives Compensation: The Role of Corporate Ownership Structure in Japan

  • Mazumder, Mohammed Mehadi Masud
    • The Journal of Asian Finance, Economics and Business
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    • v.4 no.3
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    • pp.35-43
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    • 2017
  • This paper explores the impact of corporate control, measured by ownership structure, on top-executives' compensation in Japan. According to agency theory, the pay-performance link is expected to be affected by the firm's ownership structure. Using a sample of 4,411 firm-year observations (401 firms for the 11-years period from 2001 to 2011) for Japanese non-financial firms publicly traded on the first section and second section of the Tokyo Stock Exchange (TSE), this study demonstrates that institutional ownership (both financial and corporate) is negatively related to the level of executives' compensation. Such finding is in line with efficient monitoring hypothesis which claims that the presence of institutional shareholders provides direct monitoring over managers, limits managerial self-dealing and curves the increase in top-executives pay. On the other hand, the results also show that managerial ownership is positively related to their compensation which supports managerial power theory hypothesis, i.e. management-controlled firms are more likely to extract more compensation from the business than other firms. Overall, this study confirms that corporate control has significant impact on cash compensation paid to Japanese top-executives after controlling the conventional pay-performance relationship.

A Conformational Isomer of Soulattrolide from the Stem Bark of Calophyllum symingtonianum and Its Antibacterial Activity

  • Susanti, Deny;Attoumani, Nissad;Taher, Muhammad;Rezali, Mohd Fazlin;Sohrab, Md. Hossain;Hasan, Choudhury Mahmood;Zakaria, Zainul Amiruddin
    • Natural Product Sciences
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    • v.24 no.1
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    • pp.47-53
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    • 2018
  • Callophylum symingtonianum (Guttiferae), an evergreen broad-leaved tree that usually grows in hill forests, can be found distributed in the Malay Peninsula. The barks, leaves, flowers and seeds is often used medicinally to treat diarrhea and rheumatism. In the present study, we isolated two inophyllum type coumarins, 12-O-ethylinophyllum D (1) and iso-soulattrolide (2) from the stembarks of C. symingtonianum together with their antibacterial activity. The compounds were isolated by chromatographic methods on a silica gel. The structures were established by spectroscopic methods including UV, IR, (1D and 2D) NMR and mass spectrometry as well as by comparison with several literature sources. The antibacterial activity of those compounds was tested using a disc-diffusion assay against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa. Both compound exhibited mild inhibition against P. aeruginosa with both $111{\mu}g/ml$ MIC value. Compound 2 also inhibits S. aureus with $25{\mu}g/ml$ MIC value.

Designing a Mobile Based Library Information and Service Delivery System: A Model Plan for Libraries of Bangladesh

  • Elahi, Md. Hasinul
    • Journal of Information Science Theory and Practice
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    • v.4 no.3
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    • pp.57-70
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    • 2016
  • Purpose The purpose of the study is to identify the need of a mobile based library information and service delivery system in developing countries, identify the services that are possible to provide with the help of mobile phones and their applications, design a mobile based library information and service delivery system, and identify major challenges regarding mobile based library information and service delivery systems.Design/ Methodology/ Approach The research is exploratory in nature. This paper is based on a review of literature, survey information, and on the author’s own viewpoints. A comprehensive search of scientific literature has been done along with a survey for validating the necessity of designing mobile based library information and service delivery systems. Responses to closed-ended questions in particular on 7-point Likert scales were analyzed using the descriptive analysis techniques of SPSS 20.0 and responses to other closed-ended questions were analyzed using general statistics.Findings The research indicates that users of academic libraries, especially students and faculty members, have a positive notion regarding designing and implementing a mobile based library information and service delivery system. It also reveals user opinions regarding the possible problems associated with the design and implementation of a mobile based library information and service delivery system.Originality The paper explores mobile based library information and service delivery systems for better and faster service provision to its potential users.

Analgesic, cytotoxic and antioxidant activities of Trewia polycarpa bark

  • Rahman, Md Shafiur;Sadhu, Shamir Kumar;Hasan, Choudhury Mahmud
    • Advances in Traditional Medicine
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    • v.6 no.2
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    • pp.121-125
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    • 2006
  • The crude ethanol extract of the stem bark of Trewia polycarpa (Family: Euphorbiaceae) was subjected to acetic acid induced writhing inhibition, Brine Shrimp lethality bioassay and 1, 1-diphenyl-2-picryl hydrazyl free radical scavenging assay for screening of analgesic, cytotoxic and antioxidant activity respectively. The extract produced significant (P < 0.001) writhing inhibition in acetic acid induced writhing in mice at the dose of 125, 250 and 500 mg/kg body weight respectively, which were comparable to the standard drug diclofenac sodium. The extract showed significant lethality to Brine Shrimp and the $LC_{50}$ value was $8\;{\mu}g/ml$. The extract showed prominent free radical scavenging activity ($IC_{50}$ about ${\sim}10\;{\mu}g/ml$) compare to standard drug ascorbic acid ($IC_{50}about\;{\sim}15\;{\mu}g/ml$). The results tend to suggest that the crude ethanol extract of the bark might possess analgesic, cytotoxic and antioxidant activities or active constituent(s) responsible for the activities.

A study on the general characteristics of Kahn's healthcare buildings - with the comparative study from historical and contextual standpoints - (루이스 칸의 병원건축에 나타난 일반적인 특성에 관한 연구 - 시대적 문맥적 비교와 함께 -)

  • Lim, Yeonghwan;Kim, Jihwan
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.15 no.4
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    • pp.13-21
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    • 2009
  • Healthcare design is always challenged to come up with the rapid changes in healthcare system and industry as well as complicated planning requirements. This thesis aims to grab good instructions from Louis I Kahn who designed more than 15 healthcare projects during his entire life, from the winning project of the student competition in 1920 to Ayub hospital in Dhaka, Bangladesh after his death. His many hospital projects are deeply related to his famous projects such as Yale Art gallery, Philips Exeter Library, and Sher-E-Bangla Nagar national capital of assembly hall. But, it is not easy to find the researches about his hospital projects among many books and theses about him. Thus, this thesis investigates them and their contextual and historical relationships in order to find the way to apply his knowledge and philosophy about healthcare design to the modern hospital projects. We expect that it will promote more following researches for his healthcare projects.

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UPRIGHT DRAWINGS OF GRAPHS ON THREE LAYERS

  • Alam, Muhammad Jawaherul;Rabbi, Md. Mashfiqui;Rahman, Md. Saidur;Karim, Md. Rezaul
    • Journal of applied mathematics & informatics
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    • v.28 no.5_6
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    • pp.1347-1358
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    • 2010
  • An upright drawing of a planar graph G on k layers is a planar straight-line drawing of G, where the vertices of G are placed on a set of k horizontal lines, called layers and no two adjacent vertices are placed on the same layer. There is a previously known algorithm that decides in linear time whether a planar graph admits an upright drawing on k layers for a fixed value of k. However, the constant factor in the running time of the algorithm increases exponentially with k and makes it impractical even for k = 3. In this paper, we give a linear-time algorithm to examine whether a biconnected planar graph G admits an upright drawing on three layers and to obtain such a drawing if it exists. We also give a necessary and sufficient condition for a tree to have an upright drawing on three layers. Our algorithms in both the cases are much simpler and easier to implement than the previously known algorithms.

MBR technology for textile wastewater treatment: First experience in Bangladesh

  • Saha, Pradip;Hossain, Md. Zakir;Mozumder, Md. Salatul I.;Uddin, Md. Tamez;Islam, Md. Akhtarul;Hoinkis, Jan;Deowan, Shamim A.;Drioli, Enrico;Figoli, Alberto
    • Membrane and Water Treatment
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    • v.5 no.3
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    • pp.197-205
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    • 2014
  • For the first time in Bangladesh, a bench scale membrane bioreactor (MBR) unit was tested in treating a textile wastewater in the industry premises of EOS Textile Mills LTD, Dhaka for three months. The performance of the unit was compared with that of the conventional activated sludge treatment plant, which is in operation in the same premises. The COD and BOD removal efficiency of the MBR unit reached to around 90% and 80% respectively in 20 days whereas the removal efficiency of the conventional treatment plant was as low as 40-50% and 38-40% respectively. The outlet COD and the BOD level for the MBR unit remained stable in spite of the fluctuation in the feed value, while the conventional effluent treatment plant (ETP) failed to keep any stabilized level. The performance of the MBR unit was much superior to that of the functional ETP and the water treated by the MBR system can meet disposal standard.