• Title/Summary/Keyword: DfE

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Study on Relationship between Iris Constitution and Apolipoprotein E Gene Polymorphism

  • Kang, Sung-Do;Hwang, Woo-Jun;Kim, Kyung-A;Kim, Kyung-Sik;Lee, Ho-Sub;Kim, Jong-Uk;Choi, Sung-Yong;Jin, Kyong-Son
    • The Journal of Korean Medicine
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    • v.24 no.4
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    • pp.25-33
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    • 2003
  • lridology, a form of complementary and alternative medicine (CAM), is the diagnosis of medical conditions through noting irregularities of the pigmentation in the iris. lridological constitution has a strong familial aggregation and is implicated in heredity. Apolipoprotein E (apoE) gene polymorphism is one of the most well studied genetic markers of vascular disease. I investigated the relationship between iridological constitution and apoE polymorphism. I classified 87 hypertensive patients with family history of cerebral infarction and 79 controls according to iris constitution, and determined apoE genotype. Neurogenic type in hypertensives was 32.2% compared with 16.5% in controls (P<0.001). No differences in the apoE genotypes frequencies were observed in patients compared with those in controls ($x^2=0.726$, df-=2, P=0.696). However, in a population with ${\varepsilon}3/{\varepsilon}4$ genotype, the frequency of neurogenic constitution was significantly higher in hypertensives than in controls (60% vs. 0%) ($x^2=5.265$, df=l, P=0.022). These results could imply that apoE ${\varepsilon}3/{\varepsilon}4$ genotype and neurogenic iris constitution are risk factors for hypertension.

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An Amplitude Comparison Direction-Finding Antenna Assembly for Mounting on a Small Flight Vehicle (소형 비행체 탑재를 위한 크기 비교용 방향 탐지 안테나 조립체)

  • Kim, Jaesik
    • Journal of the Korea Institute of Military Science and Technology
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    • v.23 no.5
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    • pp.459-465
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    • 2020
  • In this paper, a compact antenna assembly for an amplitude comparison direction-finding(DF) method for a small flight vehicle is presented. Designed antenna assembly consists of four antennas and it is mounted on a radius of 1.45 λc where λc corresponds to the wavelength of the center frequency. To achieve compactness and robustness of the assembly, the elements are fed by end-launch feeding method and have modified aperture shapes of E- or H-sectoral horns. The feeding part consists of SMA connector, stepped impedance matching structure, and square waveguide of 0.6 λc × 0.6 λc. To achieve different main beam directions for every antenna which is required condition for amplitude comparison DF method, all apertures of the antennas are inclined and it makes the main beam direction of each antenna to top, bottom, left, and right with respect to the axis of the platform. To verify the validation of DF performance of the presented antenna assembly, amplitude comparison curves using measurement results are presented. The bandwidth of the antennas are above 3.2 % in Ku-band(VSWR ≤ 2:1).

Link Adaptation and Selection Method for OFDM Based Wireless Relay Networks

  • Can, Basak;Yomo, Hiroyuki;Carvalho, Elisabeth De
    • Journal of Communications and Networks
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    • v.9 no.2
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    • pp.118-127
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    • 2007
  • We propose a link adaptation and selection method for the links constituting an orthogonal frequency division multiplexing (OFDM) based wireless relay network. The proposed link adaptation and selection method selects the forwarding, modulation, and channel coding schemes providing the highest end-to-end throughput and decides whether to use the relay or not. The link adaptation and selection is done for each sub-channel based on instantaneous signal to interference plus noise ratio (SINR) conditions in the source-to-destination, source-to-relay and relay-to-destination links. The considered forwarding schemes are amplify and forward (AF) and simple adaptive decode and forward (DF). Efficient adaptive modulation and coding decision rules are provided for various relaying schemes. The proposed end-to-end link adaptation and selection method ensures that the end-to-end throughput is always larger than or equal to that of transmissions without relay and non-adaptive relayed transmissions. Our evaluations show that over the region where relaying improves the end-to-end throughput, the DF scheme provides significant throughput gain over the AF scheme provided that the error propagation is avoided via error detection techniques. We provide a frame structure to enable the proposed link adaptation and selection method for orthogonal frequency division multiple access (OFDMA)-time division duplex relay networks based on the IEEE 802.16e standard.

A Noble Therapeutic Approach of Atopic dermatitis by Development of Th2 Chemokine Inhibitors from Natural Products : Inhibitory Effect of Sophora flavescens Extract in Atopic Dermatitis Model mice, NC/Nga (천연물 유래 Th2 케모카인 억제제 발굴에 의한 새로운 아토피 피부염 치료기술 개발 : 아토피 피부염 모델 NC/Nga 마우스에서 고삼 추출액의 억제 효과)

  • Jeong, Seung-Il;Choi, Byung-Min;Yun, Young-Gab;Lee, Jang-Won;Jang, Seon-Il
    • Herbal Formula Science
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    • v.17 no.1
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    • pp.141-151
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    • 2009
  • We investigated the inhibitory effect of an oral administration of a Sophora flavescens Aiton ethanol extract (SFE) on the development of atopic dermatitis (AD) by using NC/Nga model mice. The induction of atopic dermatitis-like lesion was conducted by the removal of the back hairs and topical application of a mite antigen (Dermatophagoides farinae, Df) on to the back skin twice a week for 8 weeks. SFE was orally administered at a different doses (100-400 mg/kg). Atopic dermatitis-like skin lesions were evaluated by dermatitis scores, skin histology and immunological parameters (serum levels of IgE, TARC/CCL17, MDC/CCL22, and CTACK/CCL27). Oral administration of SFE significantly inhibited the clinical sign of Df-induced atopic dermatitis, including dermatitis score and leukocyte infiltration. Moreover, SFE suppressed significantly the serum IgE and Th2 chemokine (TARC/CCL17, MDC/CCL22, and CTACK/CCL27) levels in a concentration dependent manner. These results suggest that oral administration of SFE could reduce significantly the clinical signs and Th2 chemokines in Df-induced atopic dermatitis model mice. Therefore, SFE may be effective substances for the management of AD in human.

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환경을 고려한 설계(DfE)

  • 유영준
    • Environmental engineer
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    • v.19 s.198
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    • pp.16-20
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    • 2003
  • 다사다난했던 지난해가 가고 새해가 밝았다. 금년에 결심했던 일 중에 작심 3일로 끝난 것은 없는지 확인해 볼 때다. 전국의 많은 환경관리인들은 주어진 책무를 다하기 위해 오늘도 많은 수고를 아끼지 않고 있다. 그러나 대부분의 경우 환경기술인들은 열악한 여건하에서 일을 해야 하기 때문에 많은 고생을 하고 있다. 금년 한해도 열심히 노력하는 한해가 되기를 빈다. 최고경영자의 관심부족, 인적물적자원의 부족, 관계자들의 이해부족 등의 여건 속에서 일을 해야 되

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Evaluation Factors of PDM Systems (PDM 시스템의 평가에 관한 연구)

  • 강석호;김영호;황영헌;김대환
    • The Journal of Society for e-Business Studies
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    • v.1 no.1
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    • pp.209-226
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    • 1996
  • System Intergration (SI) has resently been conceived as one df the most important tools for enforciong and reinforcing the competitiveness of an enterprise. A major concern of SI lies in sharing many types of information, such as engineering, production, finance, marketing, and so on. Product Data Management (PDM) systems are mainly concerned with product- related information, and also support a large portion of the Commerce At Light Speed (CALS) straitegy. PDM systems receive a great amount df attention form industry, A variety of PDM solutions have been introduced for the last few years, and its market has expanded very fast with an annual growth of 30%. However, in general, it is not an easy task to choose a right PDM solution for a particular company. A major purpose of this paper is to provide essential factors in evaluating PDM systems. While developing the factors. we consider the expected future trend of PDM technologies and three types of PDM-based intergration (frontward, rearward, and sideward integrations). We Propose to carry out the evaluation process in two fold. An overall evaluation is performed first to narrow down many alternatives into a few candidate systems, and then a detailed technical evaluation step follows to determine the final solution. A number of influencing factors are categorized and described in each of these steps.

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A Study on the Impact of Hotel Internal Marketing Practices on Culinary Staff Job Satisfaction and Organizational Commitment (호텔기업 내부마케팅활동이 조리종사원들의 직무만족과 조직몰입에 미치는 영향에 관한 연구)

  • Ahn, Sung-Bin;Lee, Jong-Ho
    • Culinary science and hospitality research
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    • v.21 no.2
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    • pp.60-74
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    • 2015
  • This study seeks to determine causal relationships between hotel internal marketing practices and job satisfaction, and ultimately on organizational commitment, to contribute information enabling hotel management to better understand employees working in hotel culinary departments. SPSS 18.0 and AMOS 18.0 were employed for the statistical analysis (e.g. frequency statistics, exploratory factor analysis, confirmatory factor analysis, reliability analysis, and structure equation model). Results revealed that the formulated model showed proper model fit (${\chi}^2=227.154$(df=179), p-value=0.009, CMIN/DF=1.269, RMR=0.013, GFI=0.931, AGFI=0.911, NFI=0.906, CFI=0.978, RMSEA=0.031), and confirmed construct reliability and convergent validity. Three factors (benefit package, educational training, work autonomy) were extracted based on the results of the factor analyses. Specifically, benefit package and work autonomy exhibited an effect on job satisfaction with benefit package asthe most significant factor (t-value 3.311, p<0.001), partially supporting the first hypothesis of this study. In addition, job satisfaction has found to have a positive influence in organizational commitment, confirming the second hypothesis of this study.

Moment of Inertia of Gas as a Source of Added Gravitational Field in Galaxies

  • Portnov, Yuriy A.
    • Journal of Astronomy and Space Sciences
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    • v.39 no.2
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    • pp.59-65
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    • 2022
  • In this paper we propose a new perspective for explaining galaxy rotation curves. We conjecture that there is a gravitational moment of inertia which, together with gravitational mass, contributes to the gravitational potential. We substantiate a formula for the potential created by the moment of inertia. We validate our model by computing orbital rotation velocities for several galaxies and showing that computed rotation velocities correspond to the observed ones. Our proposed approach is capable of accounting for constant gas velocities outside of a galactic disc without relying on the dark matter hypothesis. Furthermore, it addresses several problems faced by the application of the dark matter hypothesis, e.g., the absence of inward collapse of dark matter into a galaxy, the spherical distribution of dark matter around galaxies, and absence of traces of the effect of dark matter in two ultra-diffuse galaxies, NGC 1052-DF2, and NGC 1052-DF4.

Joint Precoding Technique for Interference Cancellation in Multiuser MIMO Relay Networks for LTE-Advanced System (LTE-Advanced 시스템의 다중 사용자 MIMO Relay 네트워크에서 간섭 제거를 위한 Joint Precoding 기술)

  • Malik, Saransh;Moon, Sang-Mi;Kim, Bo-Ra;Kim, Cheol-Sung;Hwang, In-Tae
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.49 no.6
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    • pp.15-26
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    • 2012
  • In this paper, we perform interference cancellation in multiuser MIMO (Multiple Input Multiple Output) relay network with improved Amplify-and-Forward (AF) and Decode-and-Forward (DF) relay protocols. The work of interference cancellation is followed by evolved NodeB (eNB), Relay Node (RN) and User Equipment (UE) to improve the error performance of whole transmission system with the explicit use of relay node. In order to perform interference cancellation, we use Dirty Paper Coding (DPC) and Thomilson Harashima Precoding (THP) allied with detection techniques Zero Forcing (ZF), Minimum Mean Square Error (MMSE), Successive Interference Cancellation (SIC) and Ordered Successive Interference Cancellation (OSIC). These basic techniques are studied and improved in the proposal by using the functions of relay node. The performance is improved by Decode-and-Forward which enhance the cancellation of interference in two layers at the cooperative relay node. The interference cancellation using weighted vectors is performed between eNB and RN. In the final results of the research, we conclude that in contrast with the conventional algorithms, the proposed algorithm shows better performance in lower SNR regime. The simulation results show the considerable improvement in the bit error performance by the proposed scheme in the LTE-Advanced system.

Gene-gene interaction in cerebral infarction patients: Relationship between apolipopreotein E gene polymorphism and Sasang-constitution

  • Um, Jae-Young;Kim, Jong-Kwan;Joo, Jong-Cheon;Kim, Kyung-Yo;Hong, Seung-Heon;Kim, Hyung-Min
    • Advances in Traditional Medicine
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    • v.4 no.2
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    • pp.104-111
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    • 2004
  • Sasang Constitutional Medicine is a major branch of Korean Traditional Oriental Medicine. The differences of disease susceptibility to be shown in Sasang constitution may be due to genetic factors. Therefore, we examined interrelationship among cerebral infarction (CI), apolipoprotein E (apoE) gene polymorphism, and Sasang constitutional classification. ApoE is a key protein modulating the highly atherogenic apoB containing lipoproteins and is a candidate gene for the development of coronary artery disease (CAD). The ${\varepsilon}2\;and/or\;{\varepsilon}4$ alleles were the first to be implicated in premature CAD, which resulted in this polymorphism being extensively studied. We investigated the association between apoE genotype and CI by case-control study in a Korean population. We also classified CI patients and control group into groups according to Sasang Constitutional Medicine. 196 CI patients and 379 controls without CI were examined. ApoE genotype was determined by 8% polyacrylamide gel separation after DNA amplification. A significant difference in the apoE genotype distribution was observed in the CI patients compared with that in controls ($X^{2}$=14.920, df=4, P=0.005). Also, the frequency of Taeumin constitution in patients with CI was significantly higher than that in controls (58.0% vs. 36.9%; P<0.001). However, the Taeumin constitution did not enhance the relative risk for CI in the subjects with apoE ${\varepsilon}2\;and/or\;{\varepsilon}4$ alleles. No differences in the apoE genotypes frequencies were observed in the Taeumin compared with that in the other constitutions. In addition, we investigated whether the DD genotype of angiotensin converting enzyme (ACE) gene, a candidate gene for CI, was associated with CI, Taeumin constitution, and apoE polymorphism. As a result, the frequency of Taeumin constitution was significantly higher in CI patients with both apoE ${\varepsilon}3/{\varepsilon}4$ and ACE ID/DD genotypes than in the remaining Sasang constitutions (14.5% vs. 8.3% and 0%) ($X^{2}$=13.521, df=6, P=0.035). In summary, we concluded that the apoE polymorphism is a major risk factor for CI in Koreans and the ACE ID/DD genotype enhanced the relative risk for CI in the subjects with apoE ${\varepsilon}3/{\varepsilon}4$ genotype and Taeumin constitution.