• Title/Summary/Keyword: Device Agent

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Toxicity of Hematoporphyrin-Coated Magnetic Ferrofluid in Rats

  • Hwang Youn-Hwan;Lim Jong-Hwan;Park Byung-Kwon;Kim Myoung-Suk;Kim Chong-Oh;Yun Hyo-In
    • Toxicological Research
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    • v.22 no.1
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    • pp.55-59
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    • 2006
  • The purpose of this study was to investigate the toxicity of hematoporphyrin-coated magnetic ferrofluid (HP-MF) through intravenous administration in Sprague-Dawley rats. Each group was treated with either saline, or the HP-MF at 0.5, 1, 1.5, 2 and 4 ml/kg body weight (b.w.) for the observation of survival rate, clinical symptoms, laboratory values and histopathological findings. In this study, HP-MF was evaluated for the survival rates, symptoms, laboratory values and histopathological examination after treatments. The result revealed that the animals in the group of HP-MF at 2 and 4 ml/kg b.w. showed some lethality. In serum biochemistry, the levels of AST, ALT and ALP were increased in the MF and HP-MF treated groups. However, histopathological examination for the suspected organs showed no evidence of hepatotoxicity and nephrotoxicity of typical iron poisoning. Though the toxicity of HP-MF was higher than that of HP, long retention of hematoporphyrin via HP-MF provides additional benefit over conventional hematoporphyrin. HP-MF could be utilized as a potential photodynamic agent in cancer therapy. It is suggested to develop an efficient external magnetic device to attract hematoporphyrin in the target site, thereby enabling to administering a small amount of HP-MF.

SELF-ADHESION OF LOW-VISCOSITY COMPOSITES TO DENTIN SURFACE (상아질에 대한 저점도 복합레진의 자가접착에 관한 연구)

  • Cho, Tae-Hee;Choi, Kyoung-Kyu;Park, Sang-Hyuk;Park, Sang-Jin
    • Restorative Dentistry and Endodontics
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    • v.28 no.3
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    • pp.209-221
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    • 2003
  • The objectiveness of this study was to evaluate whether low-viscosity composite can bond effectively to dentin surface without bonding resin. The low-viscosity composites being 50wt% filler content were made by the inclusion of bonding resin of two self-etching systems(Cleafil SE Bond, Unifil Bond) varied with contents as 0, 10, 20, 30, 40, 50wt%. Exposed dentin surfaces of extracted 3rd molars are used. Dentin bond strengths were measured. The tests were carried out with a micro-shear device placed testing machine at a CHS of 1mm/min after a low-viscosity composite was filled into an iris cut from micro tygon tubing with internal diameter approximately 0.8mm and height of 1.0mm. 1 Flexural strength and modulus was increased with the addition of bonding resin. 2. Micro-shear bond strength to dentin was improved according to content of bonding resin irrespective of applying or not bonding resin in bonding procedure, and that of Clearfil SE Bond groups was higher than Unifil Bond. 3. There were no significant difference whether use of each bonding resin in bonding procedure for S-40, S-50, U-50(p>0.05). 4. In SEM examination, resin was well infiltrated into dentin after primed with self-etching primer only for S-50 and U-50 in spite of the formation of thinner hybrid layer. Low viscosity composite including some functional monomer may be used as dentin bonding resin without an intermediary bonding agent. It makes a simplified bonding procedure and foresees the possibility of self-adhesive restorative material.

Design and Implementation of a Location-Based Push-Service Platform (위치기반 푸쉬서비스 플랫폼 설계 및 구현)

  • Shim, Jae-Min;Lee, Eung-Jae;Ju, Yang-Wan;Nam, Kwang-Woo;Ryu, Keun-Ho
    • Journal of Korea Spatial Information System Society
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    • v.11 no.4
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    • pp.47-55
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    • 2009
  • As the wireless internet technology such as mobile phone, WIBRO, HSDPA develops, customized location-based services for traffic, tourism, shopping, and emergency relief has lately attracted attention. For giving customized services. we should consider dynamic characteristics of moving object which continuously change their location. In this paper, we define the context trigger type of moving object and design triggering method for processing context generated by moving object. Also we propose location-based push service platform including context trigger of moving object for supporting location-based information to user. The proposed system gathers moving object stream from the terminal based on MS-assisted or Stand-alone positioning mode of embedded GPS in terminal extract user context by user device agent, and send context information to server.

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The Manufacturing Process and Characteristic Analysis of BKNO3 Metal-Explosive for PMD (PMD용 BKNO3 금속화약의 제조공정 및 특성분석)

  • Shim, Jungseob;Kim, Sangbaek;Ahn, Gilhwan;Kim, Junhyung;Ryu, Byungtae
    • Journal of the Korean Society of Propulsion Engineers
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    • v.22 no.3
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    • pp.90-96
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    • 2018
  • This study investigated the manufacturing process and characteristics of $BKNO_3$ (Boron Potassium Nitrate) as a pyrotechnic propellant that is commonly used in the aerospace, defense, and automobile industries. The solid mixture was composed of oxidizing agent, fuel, and binder. Evaporation process was used to uniformly mix the raw materials. The optimal ratio of composition was designed through the CEA program analysis of the material characteristics and thermal responses. Further the size, shape, sensitivity, and calorimetry characteristics were studied.

Improvement of Smart Surveillance Service using Service Priority (서비스 우선순위를 이용한 스마트 관제 서비스의 개선)

  • Seong, Dong-Su
    • Journal of Digital Contents Society
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    • v.19 no.5
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    • pp.1003-1010
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    • 2018
  • When an applicant requests the emergency situation call or safe return service using a smart device, the smart surveillance service can select the CCTV(closed circuit television) cameras around the applicant using applicant's location information, then automatically takes a photograph to track the applicant. Since the surrounding CCTV camera shoots the applicant continuously using location information and the applicant can be observed by the monitor agent in real time, this service can be very helpful in an applicant's emergency situation or safe return. The existing smart surveillance service does not consider the priority of the emergency situation call and safe return service. Therefore, there is the disadvantage that the applicant who requests an emergency situation call service can not be photographed when safe return service has already preoccupied CCTV cameras which are capable of taking a picture of the applicant. The proposed smart surveillance service improves this disadvantage by using service priority.

Validity and Reliability of the Plaque Score Using Qraycam (Qraycam을 이용한 치면세균막 검사의 타당도와 신뢰도)

  • Kim, Mi;Lee, Su-Young;Cho, Young-Sik
    • Journal of dental hygiene science
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    • v.15 no.3
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    • pp.377-382
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    • 2015
  • The purpose of this study was to evaluate the validity and reliability of plaque scoring system using new Qraycam (All in One Bio, Korea) device which enables plaque score without tooth disclosing. This study measured Quigley-Hein index and plaque control record by both Qraycam and disclosing agent on 64 elderly people and checked degree of congruence between the two methods. Reliability was evaluated with the mean of measured values, kappa index and intraclass correlation coefficient statistical analysis. The analysis of the plaque scores showed a high agreement between the measured values according to the method of measurement and the measured part. The mean of plaque index of anterior labial were not significantly different according to measurement method. The kappa index was higher by Qraycam and tooth disclosing method of plaque index. Therefore, it was verified that Qraycam has sufficient reliability as screening tool for plaque scoring system.

A Study on the Development of Intelligent Contents and Interactive Storytelling System (지능형콘텐츠 개발과 인터렉티브 스토리텔링 시스템 연구)

  • Lee, Eun Ryoung;Kim, Kio Chung
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.423-430
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    • 2013
  • The development of information technology introduced digital contents and Social Network Services(SNS), and allowed the virtual transaction and communication between users called "the experience knowledge" advanced from "the objective knowledge." This paper will analyze interactive storytelling system creating different types of stories on narrative genre about family history, personal history and so on. Through analysis on narrative interviews, direct observations, documentations and visual records, contents about CEO story, corporate story, family story and especially family history will be categorized into sampleDB and informationDB. Accumulated contents will allow the user to increase the value and usage of the contents through interactive storytelling system by restructuring the contents on family history. This research has developed writing tool data model using different digital contents such as texts, images and pictures to encourage open communications between first generations and third generations in Korea. Furthermore, researched about connected system on interactive storytelling creation device using various genre of family story that has been data based.

Design of Web Retrieval Component for Marine Leisure Information Database (해양레저정보 데이터베이스 구축을 위한 웹 탐색 컴포넌트 설계)

  • Choi, Hong-Seok;Jung, Sung-Hun;Ahn, Seong-Hwan;Yim, Jae-Hong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.2
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    • pp.142-145
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    • 2005
  • According as marine leisure industry has developed and the demand of leisure culture has increased rapidly, a desire about service which supply marine safety and connect marine information is enlarging. We wish to develop contents of download form that supply geographic information of Electronic Navigational Chart(ENC) in the marine that is digitalized to carrying along terminal of WIPI base and various informations for marine leisure. For this, DB that offer ENC and additional information should be constructed. Also, we need server(CPS; Contents provider Server) that offer required contents. In this paper, we design web retrieval component which store request information to database. When consumer required necessary information through personal mobile device, CPS can inform that. So, we wish to develop web retrieval agent component that parse informations in various World Wide Webs, and store to database.

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THE EFFECT OF VARIOUS DESENSITIZING AGENTS ON THE PERMEABILITY OF HUMAN DENTIN (수종의 desensitizing agent가 상아질 투과도에 미치는 영향)

  • Chon, Young-Eui;Jeong, Il-Young;Youn, Tae-Chul
    • Restorative Dentistry and Endodontics
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    • v.24 no.2
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    • pp.322-329
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    • 1999
  • The hydrodynamic theory of dentin sensitivity states that movement of tubular contents or tubular fluid, in either direction of dentinal tubule, causes dentin sensitivity. A corollary of that theory is that anything that can decrease dentinal fluid movement or dentin permeability should decrease dentin sensitivity. A wide variety of physicochemical methods have been used to reduce the permeability and sensitivity of exposed dentin. The purpose of this study was to evaluate the ability of 4 kinds of clinical desensitizing agents(2% NaF, 30% Potassium oxalate, MS Coat$^{(R)}$, Tubulitec system$^{(R)}$) to reduce the rate of fluid flow through dentin in vitro. Sixty coronal dentin discs, 1mm in thickness, were prepared from extracted third molars, free from decay and wear. Dentin discs were treated with 3% EDTA(Tubulicid Plus$^{(R)}$(Dental Therapeutics AB, Sweden)) to remove the smear layer and debris occluding the tubular orifices. After placing the discs in a split chamber device, the rate at which physiologic saline solution could filter across dentin under 150cm $H_2O$ hydrostatic pressure was measured. The occlusal side of the discs were then treated with MS Coat$^{(R)}$, 2% NaF, Tubulitec system$^{(R)}$, and 30% Potassium oxalate, and the filter ratio of the saline solution was measured again. The following conclusions were drawn : 1. Hydraulic conductance which was measured after the application of desensitizing agents was decreased in all the groups(p<0.05). 2. % change of hydraulic conductance was compared but no significant difference was found among the four desensitizing agents(p>0.05). 2% NaF, 30% Potassium oxalate, MS Coat$^{(R)}$ and Tubulitec system$^{(R)}$ decreased the permeability of dentin. It is considered that above four agents can be used in treating the hypersensitive teeth.

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Study on Chemical Removal of Nitric Oxide (NO) as a Main Cause of Fine Dust (Air Pollution) and Acid Rain

  • Seo, Hyeon Jin;Jeong, Rak Hyun;Boo, Jang-Heon;Song, Jimin;Boo, Jin-Hyo
    • Applied Science and Convergence Technology
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    • v.26 no.6
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    • pp.218-222
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    • 2017
  • This study was conducted to remove $NO_x$, which is the main cause of fine dust and air pollution as well as acid rain. $NO_x$ was tested using 3% NO (diluted in He) as a simulated gas. Experiments were sequentially carried out by oxidizing NO to $NO_2$ and absorbing $NO_2$. Especially, we focused on the changes of NO oxidation according to both oxidant ($NaClO_2$) concentration change (1~10 M) and oxidant pH change (pH = 1~5) by adding HCl. In addition, we tried to suggest a method to improve $NO_2$ absorption by conducting $NO_2$ reduction reaction with reducing agent (NaOH) concentration (40~60%). It was found that NO removal efficiency increased as both concentration of oxidant and flow rate of NO gas increased, and NO decreased more effectively as the pH of hydrochloric acid added to the oxidant was lower. The $NO_2$ adsorption was also better with increasing NaOH concentration, but the NO removal efficiency was ~20% lower than that of the selective NO reduction. Indeed, this experimental method is expected to be a new method that can be applied to the capture and removal of fine dust caused by air pollution because it is a method that can easily remove NO gas by a simple device without expensive giant equipment.