• Title/Summary/Keyword: Developmental regression

Search Result 185, Processing Time 0.026 seconds

The Factors Related to the Menopausal Symptoms of Married Middle-Aged Women: Focus on the Effects of Attitudes toward Menopause and Family Related Variables (기혼 중년여성의 갱년기 증상에 영향을 미치는 변인에 관한 연구 - 폐경에 대한 태도와 가족관련 변인을 중심으로 -)

  • Kim, Eunkyung;Lee, Kyung-Hae
    • Korean Journal of Human Ecology
    • /
    • v.21 no.6
    • /
    • pp.1043-1058
    • /
    • 2012
  • The purpose of this study was to identify how attitudes toward menopause and family-related variables (living with a first child, satisfaction with children, and marital satisfaction) were associated with the perceived menopausal symptoms of middle-aged Korean females. Data for the study were based on a community sample of 628 women whose ages ranged from 45 to 60, who were currently married and had at least one child. The respondents reported lower levels of menopausal symptoms, medium levels of marital satisfaction and slightly higher levels of satisfaction with children. Feelings of tiredness, irritability, and nervousness without apparent reason, and aches in the lumbago and joints were common menopausal symptoms reported in this study. Regression analysis was conducted to investigate the effects of monthly income, educational level, employment status, attitudes toward menopause, living with a first child, satisfaction with children, and marital satisfaction on perceived menopausal symptoms. Attitudes toward menopause, living with a first child, satisfaction with children and marital satisfaction were significantly associated with perceived menopausal symptoms. In particular, marital satisfaction had the strongest effect on perceived menopausal symptoms. The results showed that in the face of the developmental challenges experienced during the menopausal transition, family-related variables served as positive reinforcement for married middle-aged women. This finding suggests that in order to improve the menopausal transition, family education programs need to be developed and offered to middle aged females who suffer from severe menopausal symptoms.

Cold-induced ginsenosides accumulation is associated with the alteration in DNA methylation and relative gene expression in perennial American ginseng (Panax quinquefolius L.) along with its plant growth and development process

  • Hao, Mengzhen;Zhou, Yuhang;Zhou, Jinhui;Zhang, Min;Yan, Kangjiao;Jiang, Sheng;Wang, Wenshui;Peng, Xiaoping;Zhou, San
    • Journal of Ginseng Research
    • /
    • v.44 no.5
    • /
    • pp.747-755
    • /
    • 2020
  • Background: Ginsenosides accumulation responses to temperature are critical to quality formation in cold-dependent American ginseng. However, the studies on cold requirement mechanism relevant to ginsenosides have been limited in this species. Methods: Two experiments were carried out: one was a multivariate linear regression analysis between the ginsenosides accumulation and the environmental conditions of American ginseng from different sites of China and the other was a synchronous determination of ginsenosides accumulation, overall DNA methylation, and relative gene expression in different tissues during different developmental stages of American ginseng after experiencing different cold exposure duration treatments. Results: Results showed that the variation of the contents as well as the yields of total and individual ginsenosides Rg1, Re, and Rb1 in the roots were closely associated with environmental temperature conditions which implied that the cold environment plays a decisive role in the ginsenoside accumulation of American ginseng. Further results showed that there is a cyclically reversible dynamism between methylation and demethylation of DNA in the perennial American ginseng in response to temperature seasonality. And sufficient cold exposure duration in winter caused sufficient DNA demethylation in tender leaves in early spring and then accompanied the high expression of flowering gene PqFT in flowering stages and ginsenosides biosynthesis gene PqDDS in green berry stages successively, and finally, maximum ginsenosides accumulation occurred in the roots of American ginseng. Conclusion: We, therefore, hypothesized that cold-induced DNA methylation changes might regulate relative gene expression involving both plant development and plant secondary metabolites in such cold-dependent perennial plant species.

Comparative Study on the Characteristics of Public Transport Users According to the Types of Transit Station Influence Areas in Seoul's Urban Railway's (서울시 도시철도 환승역세권 유형별 대중교통이용자 특성 비교연구)

  • Lim, Sam-Jin;Park, Jun-Tae;Kim, Tae-Ho
    • Journal of the Korean Society for Railway
    • /
    • v.16 no.2
    • /
    • pp.129-137
    • /
    • 2013
  • This study This study aims to identify sound developmental directions for transit-oriented development (TOD), which is a topic of interest in the field of urban development, and conducts an empirical analysis of station influence areas within Seoul according to the characteristics of transit types. The results suggest that there are differences among variables that influence demand for public transportation according to transit types. This means that it is necessary to identify improvement plans in developing public transport strategies for the capital region based on such differentiated influence factors and to build foundations to continue to increase demand for public transportation. Also, station influence areas should be developed into hubs by establishing appropriate bus-only lane networks as a supplementary means, rather than directly connecting subway stations with each other.

Factors Associated with the Degree of Quality Improvement Implementation (국내 의료기관의 질 향상 사업의 활성화에 영향을 미치는 요인 - 조직동인적 관점에서)

  • Choi, Kui-Son;Kang, Hye-Young;Cho, Woo-Hyun;Chae, Yoo-Mi;Lee, Sun-Hee
    • Journal of Preventive Medicine and Public Health
    • /
    • v.34 no.4
    • /
    • pp.363-371
    • /
    • 2001
  • Objectives : To assess the degree of quality improvement (QI) implementation and to identify its associated factors. Methods : A mailed questionnaire survey of the QI staffs at hospitals with 400 beds or more was conducted between September 15 and October 30, 2000. Of the 108 hospitals eligible for inclusion in our study, 79 participated, yielding a response rate of 73.1%. After excluding 12 hospitals that did not perform any QI activities, 117 responses from 67 hospitals were used in our analysis. The degree of QI implementation was measured using the Malcolm Baldrige National Quality Award Criteria (MBNQAC). Factors evaluated for association with the degree of QI implementation were cultural, technical, strategic, and structural factors of the hospitals. Results : The average 01 implementation score across the 7 dimensions of MBNQAC was 3.34 on a 5-point scale, with the highest score for the area of customer satisfaction (3.88) followed by information and analysis (3.59) and quality management (3.35). The results of regression analysis showed that hospitals with a ofter information system (p<0.05) and using scientific and systematic problem solving approach (p<0.01) tended to perform a higher degree of QI implementation. While statistically insignificant, positive associations were observed for the factors of group or developmental culture, the degree of employee empowerment, and the use of prospective strategy. Conclusions : It appears that the most important factors contributing to active implementation of QI in Korean hospitals were the use of scientific skills in decision making, and having a quality information system to produce precise and valid information.

  • PDF

A Case of Mitochondrial Respiratory Chain Defect with Progressive Bilateral Cararacts (진행성 양측 백내장이 동반된 미토콘드리아 질환 1례)

  • Lee, Soonie;Lee, Young-Mock
    • Journal of The Korean Society of Inherited Metabolic disease
    • /
    • v.18 no.3
    • /
    • pp.95-98
    • /
    • 2018
  • A striking feature of mitochondrial disorders is the vast heterogeneity in their clinical symptoms that ranges from a single organ to severe multisystem involvement. Though a variety of ocular symptoms such as ptosis, pigmentary retinal degeneration, external ophthalmoplegia, and optic nerve atrophy can occur in association with mitochondrial cytopathies, progressive bilateral cataracts are rare among their ocular findings. A 5-year-old girl with no previous medical history came to our hospital presenting symptoms of seizure. She started showing progressive developmental regression, increased seizure frequency, hypotonia, general weakness, dysphagia and decreased vision. Lactic acidosis was noted in metabolic screening test and we confirmed mitochondrial respiratory chain complex I defect in spectrophotometric enzyme assay using the muscle tissue. Progressive bilateral cataracts then developed and were fully evident at the age of 7. She underwent cataract extraction with posterior chamber lens implantation. We are reporting a case of mitochondrial respiratory chain defect with multiorgan involvements including bilateral progressive cataract, an uncommon ocular manifestation. Ophthalmologic evaluation is highly recommended not to overlook the possible ocular manifestations in mitochondrial disorders.

  • PDF

Interaction Effect Between Temporal Proximity of Utility Value and Self-efficacy on Interest (과제 유용가치의 시간적 근접성과 자기효능감의 상호작용이 흥미에 미치는 영향)

  • Woo, Yeon-kyoung;Kim, Sung-il;Bong, Mimi
    • (The) Korean Journal of Educational Psychology
    • /
    • v.28 no.1
    • /
    • pp.1-21
    • /
    • 2014
  • Two studies were conducted to investigate the interactive effect between temporal proximity of utility value and self-efficacy on situational interest and reengagement motivation. In study 1, university students were provided with either proximal or distal values of mental calculation task. Hierarchical regression analyses showed a significant interaction effect between distal utility value and high self-efficacy, indicating that distal utility value was more effective to induce situational interest and reengagement motivation for students with higher level of self-efficacy. In study 2, we replicated study 1 with high school students to investigate developmental differences and found the same results. These findings suggest that it is important to consider the level of self-efficacy and proximity of utility value in designing value intervention program.

Relationship between Parenting Attitude and Child Development (부모의 양육태도와 아동발달의 관계)

  • Baek, Soon-Gi;Kim, Do-Jin
    • Journal of the Korea Convergence Society
    • /
    • v.10 no.10
    • /
    • pp.267-274
    • /
    • 2019
  • The purpose of this study was to investigate the relationship between parenting attitude and child development. For this purpose, a survey was conducted to parents and children who visited child development centers and child-related welfare institutions located in Seoul and the Seoul metropolitan area. Total 230 pieces of survey papers were prepared, and 183 of them - except for 47 copies which were judged to be unreliable were used for the test analysis. Data analysis was performed using SPSS version 18.0 and descriptive statistical analysis was performed to analyze general characteristics of the subjects. In order to analyze the parenting attitude and developmental relationship of the children, the regression analysis was performed. Parents' parenting attitude - especially pressure and excessive expectation were found to have an effect on self-ridicule behaviors of children, and supervision and excessive expectation were found in small muscle exercise. Achievement pressure and excessive expectation were also the main variables in expression language and language understanding. Achievement pressure, director and excessive expectation were found to have effects on children's cognitive development.

Study on the indoor exposure factors of phthalates using bio-monitoring data (생체시료를 이용한 프탈레이트의 실내 노출인자 연구)

  • Yang, Ji Yeon;Shin, Dong Chun;Lee, Si Eun;Lee, Geon Woo;Kim, Joon Hyeog;Lee, Yong Jin;Lim, Young Wook
    • Journal of odor and indoor environment
    • /
    • v.17 no.4
    • /
    • pp.315-321
    • /
    • 2018
  • Phthalate is an endocrine disruptor that interferes with homeostasis and developmental regulation. It is highly toxic to the environment and is associated with various diseases of the human body. Using biological samples from 140 adult subjects, to evaluate the influencing factors which are related to contaminant concentration levels, we used correlation analysis and multiple regression analysis. Lastly, in order to analyze the health effects related to exposure to phthalates, we conducted a risk assessment by estimating acceptable daily intake exposure according to the influential factors. When we compared the concentration level according to influential factors, in general, the subjects who had engaged in home remodeling work had higher urinary phthalate metabolite concentrations levels than the subjects who had not engaged in home remodeling work. We can confirm statistically significant differences in DBP metabolites. In addition, we can confirm the concentration appeared higher in the categories such as using air freshener, sofa and foods. Through conducting a risk assessment of DEHP, BBzP, DiBP, and DnBP by using data on phthalate metabolite concentration in urine, it was found that the average concentration of all metabolites did not exceed TDI.

A Study of Functional Disability in a Rural, Community-Dwelling Elderly Population (농촌 지역사회 거주 노인의 기능장애에 관한 연구)

  • Park, Sol-Bi;Park, Kyoung-Young;Kim, Hyeon-June
    • Journal of The Korean Society of Integrative Medicine
    • /
    • v.9 no.4
    • /
    • pp.1-9
    • /
    • 2021
  • Purpose : The purpose of this study was to investigate functional disability for the elderly in rural Korea and to identify influencing factors of functional disability. Methods : The data were collected for 76 community-dwelling elderly in rural area and above 65 years. We assessed cognitive function, functional disability, depression using LACLS, WHODAS 2.0, SGDS-K. Data were analyzed using descriptive statistics for general characteristics of subjects, Spearman's correlation among LACLS, SGDS-K, WHODAS 2.0, age, educational levels. And multiple regression was used to find influencing factors of functional disability. Results : As a result of this study, we identified that WHODAS 2.0 total score was 50.59, summary score was 9.94 and functional disability of the elderly in rural area is in the 70th percentile. The highest level of disability occurred in areas related to 'life activities (household)', 'participation in society' and the lowest level of disability occured in areas of 'self-care', 'getting along with people'. Functional disability was significantly correlated with age (r=.398), cognitive function (r=-.547), depression (r=-.563) but not educational levels (r=-.215). Finally, we confirmed that depression (𝛽=.371), cognitive function (𝛽=-.263), widowed status (𝛽=.303), age (𝛽=.272), non-participation of community program (𝛽=.165) was significantly influencing factors of functional disability and the explanatory power of these factors was 52.80 %. Conclusion : This study revealed important factors of functional disability. Therefore, we need to consider these factors when we developed program related to health for the elderly (aged > 65 years) in rural Korea. Further, we need to standardize WHODAS 2.0 in order to enhance its applicability in clinical practices.

Nonfatal injuries in Korean children and adolescents, 2007-2018

  • Yeon, Gyu Min;Hong, Yoo Rha;Kong, Seom Gim
    • Clinical and Experimental Pediatrics
    • /
    • v.65 no.4
    • /
    • pp.194-200
    • /
    • 2022
  • Background: Injury is the leading cause of death or disability in children and adolescents. Rates of deaths from injuries have recently declined, but studies of the occurrence of nonfatal injuries are lacking. Purpose: This study aimed to investigate nonfatal injuries in children and adolescents younger than 20 years based on data from the Korean National Health and Nutrition Survey, 2007-2018. Methods: A questionnaire survey was conducted to determine whether children and adolescents had experienced an injury requiring a hospital visit in the previous year. We investigated each injury's risk factors and characteristics. Results: Of a total of 21,598 children and adolescents, 1,748 (weighted percentage, 8.1%) experienced one or more injuries in the previous year. There was no yearly difference in the proportion of injuries experienced. Among the male subjects, 10.0% had an injury experience; among the female participants, 6.1% had an injury experience (P<0.001). The highest rate was 9.0% in children aged 1-4 years. In multivariate logistic regression analysis, male sex; having an urban residence; having restricted activity due to visual, hearing, or developmental impairment; and attention deficit/hyperactivity disorder were significant risk factors for injury experience. The characteristics of up to 3 injuries per patient were investigated, and 1,951 injuries were analyzed. Falls and slips accounted for 34.9%, collisions for 34.1%, and motor vehicle accidents for 11.3% of the total injuries. Ninety-six percent of injuries were unintentional, 20% caused school absences, and 10% required hospitalization. Conclusion: Among Korean children and adolescents, 8.1% experienced injuries at least once a year with no significant differences in incidence over the past 12 years. Greater attention and effort to prevent injuries are needed.