• Title/Summary/Keyword: Developmental process

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Cold-induced ginsenosides accumulation is associated with the alteration in DNA methylation and relative gene expression in perennial American ginseng (Panax quinquefolius L.) along with its plant growth and development process

  • Hao, Mengzhen;Zhou, Yuhang;Zhou, Jinhui;Zhang, Min;Yan, Kangjiao;Jiang, Sheng;Wang, Wenshui;Peng, Xiaoping;Zhou, San
    • Journal of Ginseng Research
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    • v.44 no.5
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    • pp.747-755
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    • 2020
  • Background: Ginsenosides accumulation responses to temperature are critical to quality formation in cold-dependent American ginseng. However, the studies on cold requirement mechanism relevant to ginsenosides have been limited in this species. Methods: Two experiments were carried out: one was a multivariate linear regression analysis between the ginsenosides accumulation and the environmental conditions of American ginseng from different sites of China and the other was a synchronous determination of ginsenosides accumulation, overall DNA methylation, and relative gene expression in different tissues during different developmental stages of American ginseng after experiencing different cold exposure duration treatments. Results: Results showed that the variation of the contents as well as the yields of total and individual ginsenosides Rg1, Re, and Rb1 in the roots were closely associated with environmental temperature conditions which implied that the cold environment plays a decisive role in the ginsenoside accumulation of American ginseng. Further results showed that there is a cyclically reversible dynamism between methylation and demethylation of DNA in the perennial American ginseng in response to temperature seasonality. And sufficient cold exposure duration in winter caused sufficient DNA demethylation in tender leaves in early spring and then accompanied the high expression of flowering gene PqFT in flowering stages and ginsenosides biosynthesis gene PqDDS in green berry stages successively, and finally, maximum ginsenosides accumulation occurred in the roots of American ginseng. Conclusion: We, therefore, hypothesized that cold-induced DNA methylation changes might regulate relative gene expression involving both plant development and plant secondary metabolites in such cold-dependent perennial plant species.

The Literature Study Medical History of Medieval Obstetrics and Gynecology (중세(中世) 부산과(婦産科)의 의사학적(醫史學的) 연구(硏究))

  • Cho, Myun-Hwi;Park, Hyun-Kuk
    • The Journal of Dong Guk Oriental Medicine
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    • v.5
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    • pp.231-271
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    • 1996
  • Obstetrics and Gynecology include gynecology which is concerned with the treatment for the disease based on physiology and pathology of women, and obstetrics which is concerned with pregnancy delivery. These obstetics and gynecology can be said to date from the birth of human beings. This paper has carried on the studies about the generating and developing process of obstetics and gynecology. The results of this study are as follows : Distinction in Northern and Southern Dynasties were much more Obstetrics and Gynecology studying the Obstetrics and Gynecology books in that time, the study about "oncosis" (腫瘤) and forms of drug, pill, powder, pIaster were carried on. The highest distinction in Sui age were research and development on pathogenesis and cause of disease about Obstetrics and Gynecology disease and it was appeared representatively in "Zhubingyuanhoulun""諸病源候論" which was special book on cause of disease and pathogenesis and syndrome, And it was explained about abnormal vaginal discharge in this book. Obstetrics and Bynecology were developed on theory and clincis in Tang age when "Taiyshu"(太醫暑) was established. "Taiyshu"(太醫暑) taked complete charge of medical operation and education, published much excellent Obstetrics and Gynecology books than the past. Among them specially "Qianjinyaofang""千金要方" explained Obstetrics and Gynecology matter first in three volumes and "Qianjinyifang""千金翼方" explained this matter first in four volumes. This point indicate that Obstetrics and Gynecology's importance was established in Tang age, so Obstetrics and Gynecology's developmental history, Song age was the acme period. "Taiyju"(太醫局) was established in "xining""熙?" 9 year and Obstetrics belonged to one of nine departments under "Taiyun"(太醫局), so Obstetrics and Gynecology was separated from the other medical parts and it was prepared of it's progressing bases independently and appeared of changes in quality and increase in quantity about theory and prescription of Obstetrics and Gynecology, specially determination of treatment based on the differentiation of symptoms and sighs was taked a serious view. Besides four great physicians in Jing and Yuan dynasies diversified Obstetrics and Gynecology contents through their only medical theory and clinical treatment.

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The Development and the Effects of Verbalization on Representational Redescription in Children's Drawings (아동의 그림 표상 발달과정 및 언어화를 통한 표상의 촉진)

  • Park, Hee Sook
    • Korean Journal of Child Studies
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    • v.34 no.6
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    • pp.139-158
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    • 2013
  • Karmiloff-Smith was first to propose the 'Representational Redescription model'. It describes a process through which children elaborate their knowledge from the unconscious and implicit levels to the conscious and explicit levels. The model also assumes that children in perfectly explicit levels are able to express their own representation of knowledge verbally. This study was conducted to investigate Karmiloff-Smith's Representational Redescription(RR) model(1990, 1992, 1999) within the drawing domain. Additionally, how verbalization training influences children's development of representational redescription in drawing were also examined. First, 331 children (4- to 6-year-olds and an older comparison group of 7- to 9-year-olds) were asked to create six drawings of both familiar and novel topics. From these drawings, children were measured for procedural rigidity and developmental differences. Thereafter 80 5-year-olds children who were not able to manipulate their drawings with flexibility were selected. They were divided into an experimental group and two control groups. A group of verbalization training was given a session using 5 tasks. Compared to the control groups, children who practiced verbalization in the training group showed more advanced levels of representation than their previous levels in the pretest. The results were interpreted as meaning that verbalization is likely to facilitate children's reorganization of implicit knowledge within the drawing domain and to transfer this toward explicit forms. Further research needs to pay more attention to the educational applications of learning processes based on representational redescription.

Exploring Policy Reform Options for the Welfare Regime Shift in Korea (한국 복지의 새판 짜기를 위한 문제 인식과 방안 모색)

  • Hong, Kyung Zoon
    • Korean Journal of Social Welfare
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    • v.69 no.2
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    • pp.9-30
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    • 2017
  • Generally, regime shift occurs less frequently than policy change and/or government change. Regime shift needs alterations and changes along the three critical components which constitute a domestic regime: (1) the character of the socioeconomic coalition that rules the country; (2) the political and economic institutions through which power is acquired and exercised; and (3) the public policy profile that give political direction to the nation. This paper tries to examine characteristics of the welfare regime of Korea, and explore policy reform options for the welfare regime shift in Korea. From the viewpoint of livelihood security perspective, I firstly tries to examine development process of Korean welfare regime and specify the main characteristics of that regime. Secondly, I present three policy reform options: (1) reform of the formal political institutions such as electoral system and government type; (2) restructuring of the composition of government expenditure structure; and (3) reduction of the informal employment. These three policy reform options are related to the alteration of socioeconomic coalitions and the changes of the political and economic institutions. Instead of concluding remarks, I finally suggest two debate topics to the round table discussion.

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A Study on of Make-up Design with the Application of Genre Deconstruction in Hybrids (Ver. 1) (하이브리드의 탈 장르화를 응용한 메이크업 디자인에 관한 연구(제 1보))

  • Barng, Kee-Jung;Kim, Kyung-Hee
    • The Research Journal of the Costume Culture
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    • v.20 no.3
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    • pp.347-362
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    • 2012
  • Formatively and artistically aspect, a hybrid can be said to be a phenomenon in which two mutually different genres are combined. Make-up is thought to be very important to arrange the foundation available for predicting and pursuing a flow and direction of future hybrid make-up based on this, by analyzing a flow centering on hybrid trend, which was shown previously. In terms of objectives of this study, the first, aim is to suggest a model for researching make-up by grasping the developmental process and the characteristics of hybrid art through considering an art theory of hybridity, shown in make-up. The second, aim is to design make-up by analyzing trends in make-up style after deconstructing the hybrid genre. The modern make-up design through genre-deconstruction characteristics beyond diverse plurality and genre could be known to be highlighted as aesthetic characteristic by a slight attempt as communication of open space, which connects culture and genre, which had failed to be recognized and was neglected. Empirical research has, produced a work by systematically arranging make-up design. This study, identifies two kind of barrier demolition, such as the class deconstruction and the temporal, spatial disorder centering on genre deconstruction of hybrid. There are infinite possibilities in developing make-up design in line with modern sensation through aesthetic element and symbolic significance through genre deconstruction. It was the expression mode in future make-up, to providing basic data, and to strengthening competitive edge of culture and art.

A Study on the Unified Policy of the Public Library Administrative System in Korea (공공도서관 행정체계 일원화에 대한 고찰)

  • Kwack, Dong-Chul
    • Journal of the Korean Society for Library and Information Science
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    • v.50 no.1
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    • pp.25-47
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    • 2016
  • The 21st century is the era of knowledge and information, and also the age of education and culture. The importance of a public library, which stands in the center of the stream of the times, cannot be overemphasized. A public library is a reservoir of learning and culture as a base camp for achieving a creative economy and the flourishing of our culture. Many problems are caused with the promotion of unification of a public library administrative system coming to the fore as a large issue of library communities in poor surroundings where the public libraries don't observe the library laws and rules bottom of such a reservoir is splintered by drought, and its embankment is not solid. Accordingly, this study is aimed at suggesting the improvement plan by analyzing all arguments and problems in relation to the promotion of the administrative system unification of a public library. For this purpose, first, the study considered the developmental process of the discussion about public library unification; secondly, the points at issue and problems in public library unification are reviewed; finally, this study arranged and suggested the improvement plan related to public library unification.

Regulation of the Drosophila Fascin by Raf Signaling (Raf 신호에 의한 초파리 fascin의 조절)

  • Pyo, Jung-Hoon;Choi, Na-Hyun;Lee, Shin-Hae;Kim, Young-Shin;Yoo, Mi-Ae
    • Journal of Life Science
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    • v.19 no.7
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    • pp.866-870
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    • 2009
  • Fascin, a cytoskeleton actin binding protein, functions in cell adhesion and cell migration. Fascin is also known as a candidate biomarker for various cancers, however, regulatory mechanisms of fascin expression remains little understood. In this study, we found an abnormal bristle phenotype, which is similar to that of the Drosophila fascin mutant, in Drafmutant flies. Hence, we investigated whether fascin expression is regulated by Raf signaling. RT-PCR and Western blot analysis showed that Drosophila fascin expression was down-regulated in Draf mutant flies and the level was increased in larvae expressing the oncogenic form of Draf (Draf$^{got}$) under the GAL4-UAS system. Immunostaining analysis showed increased fascin in the hemocytes over-expressing Draf$^{got}$. Our results indicate that fascin expression is regulated by Raf signaling and suggest that Raf signaling may play an important role in the actin cytoskeleton-associated developmental process and tumor progression via regulation of fascin gene.

A Study on Make-up Design with Application of Genre Deconstruction in Hybrid(Ver. 2) (하이브리드의 탈 장르화를 응용한 메이크업 디자인에 관한 연구(제 2보))

  • Barng, Kee-Jung;Kim, Kyung-Hee
    • Journal of Fashion Business
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    • v.16 no.2
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    • pp.88-107
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    • 2012
  • Hybrid implies that elements in more than two are combined, and is what is merged and used complexly the technologies and materials in several fields according to the development in scientific technology and the progress in technology. In the formative and artistic aspect, the hybrid can be said to be phenomenon that two of mutually different genres are combined. The function and form in each genre, which were combined at this time, are remained wholly or partially, thereby revealing as well without hiding a fact of having been combined. In the digital communication era, the same time level was integrated into one culture, with destroying the temporal·spatial boundary. As for the objectives of this study, first, the aim is to suggest a model for researching into make-up by grasping the developmental process and the characteristics of hybrid art through considering an art theory of hybrid, which was shown in make-up. Second, the aim is to design make-up by analyzing trend by make-up style after applying the genre deconstruction in hybrid. The modern make-up design through genre-deconstruction characteristics beyond diverse plurality and genre could be known to be highlighted as aesthetic characteristic by a slight attempt as communication of open space, which connects culture and genre, which had failed to be recognized and was neglected. Through the results of this study, it could be known that there is infinite possibility in developing make-up design in line with modern sensation through aesthetic element and symbolic significance through genre deconstruction. Based on these findings, its significance can be said to be in substantially contributing to offering new sight to the design & formative characteristic and the expression mode in future make-up, to providing basic data, and to strengthening competitive edge of culture and art.

A Study on the Relationship between Mother's Child-rearing Practices and Children's Critical Thinking Abilities (어머니의 육아방식과 아동의 비판적 사고력과의 관계에 관한 연구)

  • 안순자
    • Journal of the Korean Home Economics Association
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    • v.20 no.4
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    • pp.193-204
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    • 1982
  • This study attempts to clarify the relationship between mother;s child-rearing practices and children's critical thinking abilities. More specifically this study wants to answer the questions: (a) Is there any relationship between mother's child-rearing practices and children's critical thinking abilities? (b) What dimensions of child-rearing practices are more important for children's critical thinking abilities? (c) Does the developmental process of children's critical thinking abilities show any difference according to the mother's child-rearing practices? This study is based on the conceptual model of child-rearing practices from the cognitive disciplinary viewpoint proposed by Lee et al.(1973). They polarized the child-rearing practices into the“mediated”types. These types were specified along seven dimensions of child-rearing. In general terms, the two types refer to the degree to which mother resorts to the description of concrete and immediate phenomena and immediate expression of momentary impulses, and positively reinforces such behaviors of her children. Two kinds of data were collected from 60 primary school boys and girls, and their mothers. A child-rearing practices questionnaire with 28 items was sent to the mothers. And the children were administered a critical thinking abilities test containing measures of 4 dimensions from the Ahn's Critical Thinking Measurement Technique. The major findings are those (a) the children of mothers who reported to have used more“mediated”types of child-rearing show relatively higher level of critical thinking abilities than their counterparts; (b) of the seven dimensions of child-rearing practices, the most significant are“mode of description”,“rationality-orientation”and“reward and punishment”; and (c) the“mediated”type of child-rearing practices tends to facilitate critical thinking abilities development. In conclusion, it is believed that a further refinement of this study will contribute to the development of child-rearing training program for mothers.

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Effect of QMix irrigant in removal of smear layer in root canal system: a systematic review of in vitro studies

  • Chia, Margaret Soo Yee;Parolia, Abhishek;Lim, Benjamin Syek Hur;Jayaraman, Jayakumar;de Moraes Porto, Isabel Cristina Celerino
    • Restorative Dentistry and Endodontics
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    • v.45 no.3
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    • pp.28.1-28.13
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    • 2020
  • Objectives: To evaluate the outcome of in vitro studies comparing the effectiveness of QMix irrigant in removing the smear layer in the root canal system compared with other irrigants. Materials and Methods: The research question was developed by using Population, Intervention, Comparison, Outcome and Study design framework. Literature search was performed using 3 electronic databases PubMed, Scopus, and EBSCOhost until October 2019. Two reviewers were independently involved in the selection of the articles and data extraction process. Risk of bias of the studies was independently appraised using revised Cochrane Risk of Bias tool (RoB 2.0) based on 5 domains. Results: Thirteen studies fulfilled the selection criteria. The overall risk of bias was moderate. QMix was found to have better smear layer removal ability than mixture of tetracycline isonomer, an acid and a detergent (MTAD), sodium hypochlorite (NaOCl), and phytic acid. The efficacy was less effective than 7% maleic acid and 10% citric acid. No conclusive results could be drawn between QMix and 17% ethylenediaminetetraacetic acid due to conflicting results. QMix was more effective when used for 3 minutes than 1 minute. Conclusions: QMix has better smear layer removal ability compared to MTAD, NaOCl, Tubulicid Plus, and Phytic acid. In order to remove the smear layer more effectively with QMix, it is recommended to use it for a longer duration.