• 한국사회정책
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• 제25권4호
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• pp.39-67
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• 2018

한국 복지국가는 지난 20년 동안 괄목할만한 성장과 발전을 이룩했지만, 배제와 갈등이 만연한 우리 사회의 모습은 초라하다. 본 연구에서는 이러한 한국사회의 문제점을 가부장적 자유주의에서 찾는다. 개발주의 시기부터 형성된 경제우선주의, 고용중심주의, 그리고 후견주의는 신자유주의와 결합되면서 독특한 가부장적 자유주의를 형성하였다. 개인의 안정성이 약한 상황에서 가부장주의는 한국 복지국가가 '해방적' 역할을 하는 것을 제약하는 조건이 되었다. 또한, 가부장적 자유주의 모습은 우리 사회경제적 구조를 넘어 복지국가 내부에서도 발견되고 있다. 고용연계성이 높은 사회보험이나 근로연계복지, 과도하게 중앙화된 사회서비스, 그리고 낮은 탈상품화 수준과 민간보험의 활용은 가부장적 자유주의의 단면을 잘 보여준다. 이를 극복할 복지국가의 새로운 패러다임으로 사회적 자유주의를 제시하고자 한다. 개인의 실질적 자유라는 최우선 목표를 달성하기 위해서 새로운 복지국가 전략이 필요함을 주장한다. 이와 함께 기존의 고용중심 패러다임을 탈피하고, 기존 유럽의 유연안정성을 개인의 자유 관점에서 재해석하고 발전시킨 자유안정성 개념을 운영모델로 제시하려 한다.

• Journal of Periodontal and Implant Science
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• 제49권4호
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• pp.228-236
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• 2019

Purpose: The purpose of this study was to evaluate the synergistic effect of adjunctive hyperbaric oxygen (HBO) therapy on new bone formation and angiogenesis after 8 weeks of healing. Methods: Sprague-Dawley rats (n=28) were split into 2 groups according to the application of adjunctive HBO therapy: a group that received HBO therapy (HBO group [n=14]) and another group that did not receive HBO therapy (NHBO group [n=14]). Each group was divided into 2 subgroups according to the type of bone graft material: a biphasic calcium phosphate (BCP) subgroup and an Escherichia coli-derived recombinant human bone morphogenetic protein-2-/epigallocatechin-3-gallate-coated BCP (mBCP) subgroup. Two identical circular defects with a 6-mm diameter were made in the right and left parietal bones of each rat. One defect was grafted with bone graft material (BCP or mBCP). The other defect was not grafted. The HBO group received 2 weeks of adjunctive HBO therapy (1 hour, 5 times a week). The rats were euthanized 8 weeks after surgery. The specimens were prepared for histologic analysis. Results: New bone (%) was higher in the NHBO-mBCP group than in the NHBO-BCP and control groups (P<0.05). Blood vessel count (%) and vascular endothelial growth factor staining (%) were higher in the HBO-mBCP group than in the NHBO-mBCP group (P<0.05). Conclusions: HBO therapy did not have a positive influence on bone formation irrespective of the type of bone graft material applied after 8 weeks of healing. HBO therapy had a positive effect on angiogenic activity.

• 과학교육연구지
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• 제43권2호
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• pp.258-269
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• 2019

이 연구는 핵심역량의 관점에서 STEAM 교육의 효과를 조사할 수 있는 'STEAM 교육 핵심역량 조사 도구'를 개발하였다. STEAM 교육과 관련된 국내 외 선행연구 고찰을 바탕으로 전문가 협의회를 통한 반성적 재검토와 외부 전문가의 검증을 통하여 조사도구의 초안이 완성하였다. 개발된 조사도구는 학생 408명을 대상으로 예비 조사를 실시하였고, 신뢰도 확인과 확인적 요인 분석과 같은 통계 분석을 통하여 최종 완성하였다. 최종 개발된 조사도구의 문항은 융합(7문항), 창의(11문항), 도전(5문항), 배려(9문항)의 총 32문항으로 구성되었다. 각 요인별 Cronbach's ${\alpha}$값은 .849에서 .929로 높은 신뢰도를 나타내었다. 이 연구를 통해 개발된 조사도구는 STEAM 교육의 효과를 학생의 핵심역량 관점에서 조사하는데 활용될 수 있을 것이다.

• 한국환경복원기술학회지
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• 제22권1호
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• pp.1-11
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• 2019

This study suggested that various stakeholder can be participated in regional Environment planning and practical use of policy with rapid assessment of Ecosystem Services(ES). We applied to the rapid assessment of ES method to Ansan city and local registers selected Ecosystem assets that considered to space of ES. Ecosystem assets were measured 5 types Likert scale about 37 indicators of ES and confirm the main ES through the basic statistics. Furthermore Ecosystem assets classified according to similar character of ES. Ecosystem assets of Ansan were selected 47 site and Local climate regulation, Research and education, Primary production was high among the ES indicators. As a result two main group deduced that ecological education group(such as Research and education, Habitat) and safety regulation group(such as Air regulation, Fire regulation) through the factor analysis. In terms of location characteristics of each group, the ecological education-centered ecosystem assets were located near the downtown area, while the safety regulation group was located at the outskirts, such as mountains and coasts. This indicates that the ecological education about the habitat provision can be achieved in Ansan city downtown area and that outskirts should be approached from the aspect of ecological function to establish a plan. The result of Rapid assessment of ES, which can be lead a balanced and developmental consultation when establishing polices for environment planning and management in region.

• 실내환경 및 냄새 학회지
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• 제17권4호
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• pp.315-321
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• 2018

Phthalate is an endocrine disruptor that interferes with homeostasis and developmental regulation. It is highly toxic to the environment and is associated with various diseases of the human body. Using biological samples from 140 adult subjects, to evaluate the influencing factors which are related to contaminant concentration levels, we used correlation analysis and multiple regression analysis. Lastly, in order to analyze the health effects related to exposure to phthalates, we conducted a risk assessment by estimating acceptable daily intake exposure according to the influential factors. When we compared the concentration level according to influential factors, in general, the subjects who had engaged in home remodeling work had higher urinary phthalate metabolite concentrations levels than the subjects who had not engaged in home remodeling work. We can confirm statistically significant differences in DBP metabolites. In addition, we can confirm the concentration appeared higher in the categories such as using air freshener, sofa and foods. Through conducting a risk assessment of DEHP, BBzP, DiBP, and DnBP by using data on phthalate metabolite concentration in urine, it was found that the average concentration of all metabolites did not exceed TDI.

• Molecules and Cells
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• 제44권3호
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• pp.168-178
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• 2021

The retinal pigment epithelium (RPE) forms a monolayer sheet separating the retina and choroid in vertebrate eyes. The polarized nature of RPE is maintained by distributing membrane proteins differentially along apico-basal axis. We found the distributions of these proteins differ in embryonic, post-natal, and mature mouse RPE, suggesting developmental regulation of protein trafficking. Thus, we deleted tumor susceptibility gene 101 (Tsg101), a key component of endosomal sorting complexes required for transport (ESCRT), in embryonic and mature RPE to determine whether ESCRT-mediated endocytic protein trafficking correlated with the establishment and maintenance of RPE polarity. Loss of Tsg101 severely disturbed the polarity of RPE, which forms irregular aggregates exhibiting non-polarized distribution of cell adhesion proteins and activation of epidermal growth factor receptor signaling. These findings suggest that ESCRT-mediated protein trafficking is essential for the development and maintenance of RPE cell polarity.

• 한국발생생물학회지:발생과생식
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• 제24권4호
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• pp.287-296
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• 2020

The absence of functional estrogen receptor α (Esr1) results in an overgrowth of the epididymal fat, as observed in estrogen receptor α knockout (ERαKO) mouse. The present research was aimed to evaluate expression of various molecules associated with adipocyte differentiation and maturation in the epididymal fat of ERαKO mouse at several postnatal ages by using quantitative real-time polymerase chain reaction. The highest transcript levels of all molecules were detected at 12 months of postnatal age, except leptin which the mRNA level was increased at 5 months of age and was unchanged until 12 months of age. The expression levels of CCAAT enhancer binding protein (Cebp) alpha, androgen receptor, and lipoprotein lipase were decreased at 5 months of age but increased at about 8 months of age. The mRNA levels of Cebp gamma and sterol regulatory element binding transcription factor 1 remained steady until 8 months of age. Continuous increases of transcript levels during postnatal period were found in Cebp beta, estrogen receptor (ER) beta, fatty acid binding protein 4, and delta like non-canonical Notch ligand 1. The increases of peroxisome proliferator-activated receptor gamma and adiponectin mRNA levels were detected as early as 8 months of age. The levels of fatty acid synthase and resistin transcript at 5 and 8 months of age were lower than that at 2 months of age. These findings show the aberrant expression patterns of genes related to adipocyte differentiation and maturation in the postnatal epididymal fat pad by the disruption of ER alpha function.

• 한국치위생학회지
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• 제21권2호
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• pp.183-191
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• 2021

Objectives: The purpose of this study was to identify the factors of satisfaction with regional oral health centers for people with disabilities in Korea. Methods: A survey was conducted with 784 patients who visited regional oral health care centers in Korea. A self-developed questionnaire (29 items) was adapted with a consent form and IRB (Institutional Review Board). All collected data were analyzed for statistics using SPSS version 25.0. Results: The study participants were 452 (57.7%) male patients, 207 (26.4%) aged 20-29 years old, and mostly had physical, developmental, and mental disabilities. The patients were introduced by their acquaintances, and the major reason for visit was specific dental care for the disabled. Most patients used their cars and took half to one hour to commute. The common factor affecting the comprehensive satisfaction was the facility satisfaction. Conclusions: A more comprehensive and standardized questionnaire should be developed for the annual evaluation of all centers. This study presents the basic data that can aid to activate the operation of the four oral health care centers for the disabled, which are scheduled to be implemented in the future, as well as 10 currently operated centers.

• Animal Bioscience
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• 제35권5호
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• pp.698-710
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• 2022

Objective: The objective of this study was to investigate the effects of different degrees of maternal dietary energy restriction on lipid deposition in embryonic tissues during the medium laying period (37 to 39 weeks) in Arbor Acres (AA) broiler breeders. Methods: A single factor design was adopted, and 400 AA broiler breeders (20 weeks of age) with a similar weight were randomly allocated into four groups. The birds in the control group were fed a corn-soybean meal based diet, and those in trial groups were fed diets with 80%, 70%, and 50% energy levels of the basal diet. Incubated eggs from the medium laying period were collected. Samples of developing embryos at various stages were prepared for composition analysis. Results: The embryo weight in the 80% energy group was higher than those of the other groups on embryonic day (E) 13, but at 21 E, they were significantly decreased with decreasing energy intake of the broiler breeders (p<0.05). Additionally, the levels of crude fat in tissues in the restriction groups were significantly decreased (p<0.05). The long axis and area of adipocytes in breast muscle, thigh muscle and the liver were significantly decreased (p<0.05) at 21 E in the 80%, 70%, and 50% energy groups. Conclusion: The effects of the 80% maternal dietary energy restriction energy affects egg production performance, egg quality, and nutrient deposition in egg weights, which then directly impacts on the developmental process of embryos, especially on fat utilization and deposition.

• 한국발생생물학회지:발생과생식
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• 제26권1호
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• pp.23-36
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• 2022

Pharyngeal pouches, a series of outgrowths of the pharyngeal endoderm, are a key epithelial structure governing facial skeleton development in vertebrates. Pouch formation is achieved through collective cell migration and rearrangement of pouch-forming cells controlled by actin cytoskeleton dynamics. While essential transcription factors and signaling molecules have been identified in pouch formation, regulators of actin cytoskeleton dynamics have not been reported yet in any vertebrates. Cofilin1-like (Cfl1l) is a fish-specific member of the Actin-depolymerizing factor (ADF)/Cofilin family, a critical regulator of actin cytoskeleton dynamics in eukaryotic cells. Here, we report the expression and function of cfl1l in pouch development in zebrafish. We first showed that fish cfl1l might be an ortholog of vertebrate adf, based on phylogenetic analysis of vertebrate adf and cfl genes. During pouch formation, cfl1l was expressed sequentially in the developing pouches but not in the posterior cell mass in which future pouch-forming cells are present. However, pouches, as well as facial cartilages whose development is dependent upon pouch formation, were unaffected by loss-of-function mutations in cfl1l. Although it could not be completely ruled out a possibility of a genetic redundancy of Cfl1l with other Cfls, our results suggest that the cfl1l expression in the developing pouches might be dispensable for regulating actin cytoskeleton dynamics in pouch-forming cells.