• The Journal of Pediatrics of Korean Medicine
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• v.26 no.2
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• pp.25-34
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• 2012

Objectives The purpose of this study was to find out the relationship between developmental disabilities and oriental medicine using diagnostic procedure based on the symptoms of weak children. Methods The questionnaire administrated to 42 developmental disability children in ${\bigcirc}{\bigcirc}$ Hospital's physical therapy room, and 90 general children in day care center. Results 1. The mean value of every organ's weak score was higher in developmental disability children group than that of general children group. 2. Regardless of developmental disabilities, the biggest portion among all children was lung weak children. 3. The percentage of the weak children was 38.1% in developmental disability group and 20% in general children group. 4. Heart, spleen, kidney weak children were significantly more in developmental disability group than in general children group. Conclusions Developmental disability children's weak symptom scores were higher than general children. Also, developmental disability children were more prone to weaker heart, spleen, kidney than general children.

• Journal of the Korean Home Economics Association
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• v.48 no.5
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• pp.25-48
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• 2010

The purpose of this study was to employ the Latent Growth Curve Model(LGM) to investigate the developmental trajectories of children's internalizing and externalizing problem behaviors and to identify predictors that might have an effect on change and the level of developmental trajectories. Furthermore, we classified the developmental trajectories of children's internalizing and externalizing problem behaviors, and also analyzed factors which caused differences in developmental trajectories by Semi-Parametric Group-based Modeling. This study used data from wave 1-4(2004~2008) of elementary school fourth grade panel of the Korea Youth Panel Survey(KYPS). The results showed that children's internalizing and externalizing problem behaviors changed significantly from the fourth grade of elementary school to the first grade of middle school. The predictors for developmental trajectories of children's internalizing problem behaviors were gender, self-control, parental conflict, deviant peers, and attachment to teachers. The predictors for the developmental trajectories of children's externalizing problem behaviors were gender, self-esteem, self-control, and deviant peers. The developmental trajectories of children's internalizing problem behaviors was classified into three groups. The developmental trajectories of children's externalizing problem behaviors was classified into four groups.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.10a
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• pp.149-149
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• 2003

• Knowledge Management Research
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• v.17 no.3
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• pp.23-44
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• 2016

This study examined the cause-and-effect relationships among developmental network characteristics, developmental functions, and career identity. The study analyzed the data of employees with more than two years of experience and a college degree or over qualifications, from domestic companies. For analysis, the structural equation model was applied. Most of all, it was substantiated that the structural relationships among the developmental network characteristics, developmental functions, and career identity. The specific results were as follows. First, tie strength had a positive effect on all of developmental functions but psychosocial support mediated the relationship between the tie strength and career identity. Second, an indirect relationship between indicators of network diversity and identity was not found or the indirect relationship was very weak.

• Proceedings of the Korean Society of Toxicology Conference
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• 2005.05a
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• pp.159-159
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• 2005

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.128.1-128.1
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• 2000

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.22 no.2
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• pp.120-127
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• 2011

Objectives:The purpose of this study was to verify discriminant validity and the clinical cutoff score of Child Behavior Checklist 1.5-5 in the diagnosis of developmental delayed infants. Methods:The participants were screened by Denver II which includes 156 developmental delayed infants and 288 normal infants. Chi-squared test, t-test, ROC curve analysis, odds ratio analysis were performed on the data. Results:Only 47 items out of 99 items among the CBCL 1.5-5 of total groups, 36 items of boys and 48 items of girls, discriminated developmental delayed infants well. Discriminant validity was confirmed by mean differences on the subscales of Withdrawn, Sleep Problems, Attention Problems, Internalizing Problems, Externalizing Problems, Total Problems, DSM Pervasive Developmental Problems and DSM Attention Deficit/Hyperactivity Problems between the two groups. Additionally, ROC analyses demonstrated that Withdrawn, Attention Problems, Internalizing Problems, Total Behavior Problems and DSM Pervasive Developmental Problems significantly predicted developmental delayed infants compared to normal infants. Also, the clinical cutoff score criteria adopted in the Korean CBCL 1.5-5 for subscales of Withdrawn, Attention Problems, Internalizing Problems, Total Behavior Problems and DSM Pervasive Developmental Problems were shown to be valid. Conclusion:The subscales of Withdrawn, Attention Problems, Internalising Problems, Total Behavior Problems and DSM Pervasive Developmental Problems significantly discriminated in the diagnosis of developmental delayed infants well.

• Child Health Nursing Research
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• v.8 no.3
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• pp.302-312
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• 2002

This descriptive exploratory study was conducted to analyze the results of developmental screening test using DDST and the follow-up diagnostic evaluation in one public health center, and to evaluate the feasibility of developmental screening in nursing. Samples were 373 children under 6 years who visited the public health center. Mothers' satisfaction on the developmental clinic was also determined. Summaries of the results were as follows:v 1. 0.5% of children in height and 1.9% of children in weight were included in below 3 percentile of Korean children's growth chart, but none of them showed developmental delay. 2. The results of DDST showed 92.1% of subjects were classified as normal, 3.7% as abnormal, and 4.2% as questionable among 354 children. 3. Most of children who showed the abnormal development at the first DDST were confirmed having the developmental delay at the follow-up diagnostic evaluation. On the other hand, most of children who showed the questionable development at the first DDST revealed having the normal development in follow-up screening test. 4. The result of the DDST was influenced by the birth order of the subject and delivery type. 5.The mean satisfaction score by mothers on developmental clinic was 4.35 in 5 Likert scale. In conclusion, we could certain the feasibility and usefulness of developmental screening in community and child care nursing. To fulfil the increasing needs of mothers with infants on the child development, nurses have to provide anticipatory guidance and parent education in addition to the developmental screening test. We hope to expand the developmental screening in nursing field not only of clinical setting but also of community.

• Korean Journal of Animal Reproduction
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• v.21 no.3
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• pp.275-280
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• 1997

This study was carried out to investigate on the survival and in vitro developmental rates of bisected bovine embryos by microblade, micropipette and pronase methods. Bisected embryos cultured for 1∼7 days in TCM-199 media with 10 FCS＋hormones. Survival and in vitro developmental rates was defined on in vitro culture or FDA-test. The results are summarized as follows ; 1. The survival and in vitro developmental rates of bisected bovine embryos by microblade, micropipette and pronase methods were 22.2, 16.7, 15.0% and 22.2, 23.3, 18.8%, respectively. In vitro developmental rate of bisected bovine embryos was significantly lower than that of non-bisection embryos(27.8% and 25.0%). 2. In vitro developmental rates of bovine embryos bisected for 1, 2, 4, 8, 16 cells stages during in vitro culture in 10% FCS＋TCM-199 media were 25.0, 20.0, 20.0, 15.0 and 6.7%, respectively. 3. In vitro developmental rates of intact and free-zona pellucida of bisected demi-embryos during in vitro culture in 10% FCS＋TCM-199 media were 25.6, 16.7%, respectively. 4. In vitro developmental rates of biopsied embryos and biopsied blastomeres during in vitro culture in 10% FCS＋TCM-199 media were 20.0, 11.1%, respectively.

• Toxicological Research
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• v.35 no.4
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• pp.343-351
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• 2019

Many in vitro developmental toxicity assays have been proposed over several decades. Since the late 1980s, we have made intermittent attempts to introduce in vitro assays as screening tests for developmental toxicity of inhouse candidate products. Two cell-based assays which were developed two decades apart were intensively studied. One was an assay of inhibitory effects on mouse ascites tumor cell attachment to a concanavalin A-coated plastic sheet surface (MOT assay), which we studied in the early days of assay development. The other was an assay of inhibitory effects on the differentiation of mouse embryonic stem cell to beating heart cells (EST assay), which we assessed more recently. We evaluated the suitability of the assays for screening in-house candidates. The concordance rates with in vivo developmental toxicity were at the 60% level. The EST assay classified chemicals that inhibited cell proliferation as embryo-toxic. Both assays had a significant false positive rate. The assays were generally considered unsuitable for screening the developmental toxicity of our candidate compounds. Recent test systems adopt advanced technologies. Despite such evolution of materials and methods, the concordance rates of the EST and MOT systems were similar. This may suggest that the fundamental predictivity of in vitro developmental toxicity assays has remained basically unchanged for decades. To improve their predictivity, in vitro developmental toxicity assays should be strictly based on elucidated pathogenetic mechanisms of developmental toxicity.