• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 1996.10a
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• pp.58-59
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• 1996

생활수준이 높아지면서 수경재배된 신선채소의 수요가 늘어나고 있으며, 비트와 같은 서양근채류의 이용도 증가하는 추세여서 근채류의 양액재배도 증가하리라 기대된다. 특히 비트의 경우 색소의 원료로도 이용이 많으므로 재배가 늘 것으로 보인다. 비트는 중성 내지 약알칼리성 토양에서 생육이 가장 좋은 것으로 알려져 있는데. 현재 국내 대부분의 밭토양은 산성이므로 비트 재배에 적함하지 않다고 본다. (중략)

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.475-480
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• 2016

Abandoned empty houses are largely left neglected as unused space, due to the slowdown in the real estate market that has resulted from the declination of urban functions. This research aims to analyze the characteristics of the City of Detroit's policies and regeneration efforts regarding abandoned houses, based on the perspective of unused space. This is expected to provide the baseline data for similar efforts to be applied to abandoned houses in the Korean context, thus preventing the decline of urbanism by adopting relevant policies and regeneration efforts. Some of the key features of the City of Detroit's regeneration efforts are: 1) the active participation of residents and open-data policies, 2) the diversification of regeneration strategies depending on the potential of the unused space, and 3) securing differential plurality of the regeneration processes.

• Toxicological Research
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• v.19 no.1
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• pp.45-50
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• 2003

The purpose of this study was to determine the role of substituted groups in phenolic compounds to develop an anticancer agent having strong cytotoxicity against cancer cells but weak against normal cells. The phenolic compounds used in this study were gallic acid and ferulic acid with hydroxyl and carboxyl groups, syringic acid with hydroxyl, carboxyl and methoxy groups, and pyre-gallol with hydroxyl groups. Cytotoxicities of these compounds were evaluated by MTT assay for cell viability and XTT assay for cell adhesion activity in normal human skin fibroblast (Detroit 551) and human skin melanoma (SK-MEL-3) cells. Syringic acid, gallic acid and ferulic acid decreased the cell viability and cell adhesion activity in SK-MEL-3 cells but not in Detroit 551 cells while pyrogallol decreased in both cells. The susceptibility of cell viability based on the $IC_{50}$ values of MTT assay in Detroit 551 cells was in the following order: pyrogallol > gallic acid > ferulic acid > syringic acid, while it was in SK-MEL-3 cells: Syringic acid > progallol > ferulic acid > gallic acid. These results suggest that carboxyl and methoxy groups of these compounds play an important role in selectivity of cytotoxicity in normal and cancer cells.

• The Korean Journal of Air & Space Law and Policy
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• v.11
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• pp.321-327
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• 1999

• JOURNAL OF ELECTRICAL WORLD
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• no.8 s.16
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• pp.17-22
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• 1969

본고는 지난 2월 14일과 15일 양일간에 걸쳐 Okinawa에서 유구(Ryukyu)전력공사 주최로 개최된 제8회 ${\ulcorner}$과학청소년의 날${\lrcorner}$기념행사에 참석하였던 토마스$\cdot$앨바$\cdot$에디슨재단의 전무이사인 제임스$\cdot$G$\cdot$쿡(James G. Cook)씨가 동 행사에 참석한 우수학생들에게 정찬회 석상에서 행한 강연의 원고를 번역한 것이다. 제임스$\cdot$쿡씨는 현재 토마스$\cdot$앨바$\cdot$에디슨재단의 전무이사의 요직에 재직하고 있으며 1965년에 동 재단의 상무이사로 취임하기 이전에는 5년간 Detroit 시에 있는 General Motors 회사의 모터연구소원 및 섭외담당관으로 활약하였다. 미시간주 Detroit 시 출신인 씨는 Eastern Michigan 대학에서 심리학박사학위를 받았으며 또한 정치학도 수업하였다. 씨는 동행사 참가 직후 내한하여 약 1주간 체류하면서 당 대한전기협회와 내년 4월에 한국에서 개최하기로 된 제14회 ${\ulcorner}$국제에디슨탄생일기념축전${\lrcorner}$에 관한 행사계획의 세부내용을 협의한 바 있다.

• Environmental Mutagens and Carcinogens
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• v.26 no.3
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• pp.77-85
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• 2006

2,3,7,8-Tetrachlorodibenzo-$\rho$-dioxin(TCDD) displays high toxicity in animals and has been implicated in human carcinogenesis. Although TCDD is recognized as potent carcinogens, relatively little is known about their role in the tumor promotion and carcinogenesis. It is known that TCDD can increase of cancer risk from various types of tissue by a mechanism possibly involving the aryl hydrocarbon receptor (AhR) activation. In this study, effects of TCDD on cellular proliferation of normal human skin and lung fibroblasts, Detroit551 and WI38 cells were investigated. In addition, to enhance our understanding of TCDD-mediated carcinogenesis, we have investigated process in which expression of Erk1/2, cyclinD1, oncogene such as Ha-ras and c-myc, and their cognate signaling pathway. TCDD that are potent activators of AhR-mediated activity was found to induce significant increase of cytochrome P4501A1 mRNA expression, suggesting a presence of functional AhR. These results support that CYP1A1 enzyme may be involved in the generation of TCDD-induced toxicity. Moreover mitogen-activated protein kinases (MARKs) phosphorylation and cyclin D1 overexpression are induced by TCDD, which corresponded with the progression of cellular proliferation. However, TCDD did not affected Ha-ras and c-myc mRNA expression. Taken together, it seems that TCDD are could be a part of cellular proliferation in non-tumorigenic normal human cells such as Detroit551 and WI38 cells through the upregulation of MAPKs signaling pathway regulating growth of cell population. Therefore, AhR-activating TCDD could potentially contribute to tumor promotion and Detroit551 and WI38 cells have been used as a detection system of tumorigenic effects of TCDD.

• Food Science of Animal Resources
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• v.24 no.2
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• pp.171-175
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• 2004

Insulin-like growth factor-I (IGF-I) rich fraction, which was obtained molecules ranged between 30 kDa and 1 kDa, was fractionated by ultrafiltration from bovine colostral whey with 30 kDa and 1 kDa membrane. IGF-I included in fractionated IGF-I rich fraction was confirmed by SDS-PAGE and western blotting and then the quantity of IGF-I was measured by ELISA. IGF-I concentration in IGF-I rich fraction was 10ng/mg protein. Effect of IGF-I rich fraction on in vitro proliferation of several cells was tested. IEC-6 cell proliferation rate was increased 60％. 53％, 30％, and 20％ at l0ng, 1ng, 0.1ng and IGF-I of IGF-I, respectively, compared to control group which was not supplemented by IGF-I rich fraction. IGF-I rich fraction stimulated in vitro proliferation of IEC-6 cell in a dose dependent manner by increasing cell number. Detroit 551 cell proliferation was enhanced 56％ and 26％ at 10ng and 1ng level of IGF-I, respectively, compared to control group. EL-4 cell and L6 cell proliferation was increased 53％ and 46％ at 10ng of IGF-I, respectively, compared to control group.

• Journal of the Korean Mathematical Society
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• v.34 no.2
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• pp.303-303
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• 1997

• Archives of Pharmacal Research
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• v.23 no.4
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• pp.267-282
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• 2000

Cytochrome P45O (CYP) 2E1 catalyzes the metabolism of a wide variety of therapeutic agents, procarcinogens, and low molecular weight solvents. CYP2E1-catalyzed metabolism may cause toxicity or DNA damage through the production of toxic metabolites, oxygen radicals, and lipid peroxidation. CYP2E1 also plays a role in the metabolism of endogenous compounds including fatty acids and ketone bodies. The regulation of CYP2E1 expression is complex, and involves transcriptional, post-transcriptional, translational, and post-translational mechanisms. CYP2E1 is transcriptionally activated in the first few hours after birth. Xenobiotic inducers elevate CYP2E1 protein levels through both increased translational efficiency and stabilization of the protein from degradation, which appears to occur primarily through ubiquitination and proteasomal degradation. CYP2E1 mRNA and protein levels are altered in response to pathophysiologic conditions by hormones including insulin, glucagon, growth hormone, and leptin, and growth factors including epidermal growth factor and hepatocyte growth factor, providing evidence that CYP2E1 expression is under tight homeostatic control.

• JOURNAL OF ELECTRICAL WORLD
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• no.7 s.1
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• pp.66-68
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• 1965

5월 12일로부터4일간에 걸쳐 동경에서 개최되었던 일본전기협회 제44회 통상총회에는 우리나라에서도 대한전기협회를 대표해서 한전의 진의종 부사장과 김종수 이사가 참석한 바 있다. 아래에 소개하는 글은 동 총회에 참석하였던 미국의 Walker L. Cisler씨(Detroit Edison Co. 회장$\cdot$Edison전기협회 회장$\cdot$Thomas Alva Edison재단 이사장)의 연설 전문이다. 선진제국과의 교류를 통하여 우리나라의 전기관계사업의 발전향상을 촉진하고자 함이 우리 대한전기협회의 설립목적의 하나임을 상기하면서 제자 여러분께서 많이 읽어 주실 것을 기대해 본다.