• Title/Summary/Keyword: Detriment

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Risk Assessment from Heterogeneous Energy Deposition in Tissue. The Problem of Effects from Low Doses of Ionizing Radiation

  • Le, Feinendegen;J, Booz
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.1
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    • pp.8-13
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    • 1992
  • Low doses of ionizing radiation from external or internal sources cause heterogeneous distribution of energy deposition events in the exposed biological system. With the cell being the individual element of the tissue system, the fraction of cells hit, the dose received by the hit, and the biological response of the cell to the dose received eventually determine the effect in tissue. The hit cell may experience detriment, such as change in its DNA leading to a malignant transformation, or it may derive benefit in terms of an adaptive response such as a temporary improvement of DNA repair or temporary prevention of effects from intracellular radicals through enhanced radical detoxification. These responses are protective also to toxic substances that are generated during normal metabolism. Within a multicellular system, the probability of detriment must be weighed against the probability of benefit through adaptive responses with protection against various toxic agents including those produced by normal metabolism. Because irradiation can principally induce both, detriment and adaptive responses, one type of affected cells may not be simply summed up at the expense of cells with other types of effects, in assessing risk to tissue. An inventory of various types of effects in the blood forming system of mammals, even with large ranges of uncertainty, uncovers the possibility of benefit to the system from exposure to low doses of low LET radiation. This experimental approach may complement epidemiological data on individuals exposed to low doses of ionizing radiation and may lead to a more rational appraisal of risk.

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A Study on the Cases of Seller's Fundamental Breach (근본적(根本的) 계약위반(契約違反) 조항(條項)의 적용(適用) 사례(事例)에 관한 고찰(考察) - 매도인(賣渡人)의 의무위반(義務違反)을 중심(中心)으로-)

  • Ha, Kang-Hun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.19
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    • pp.67-93
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    • 2003
  • The CISG approach was intended to make the remedial system clear, but produced ambiguity, and complexity. The CISG does not differentiate between main, auxiliary and participatory obligations. There is no distinction between breaches of main or breaches of auxiliary obligations, rather, a distinction is made between fundamental and other breaches of contract. Articles 25 gives the definition of fundamental breach of contract. This concept is the essential of avoidance and remedial system in the CISG. This concept, however, is ambiguous. The fact that the fundamentality of a breach of contract in many cases is the condition for an avoidance of contract, is expression of the trend of the CISG to preserve contracts, which I consider as essential in international trade. The elements which define a substantial detriment are extremely complex. It will become obvious that the relevant detriment is not a static element, but in many instances occurs only when the breach of contract continues. It should be added that it is the circumstances of each individual case which are relevant. It is to be stressed that a fundamental breach of contract must constitute also a non-fulfillment of a contractual obligation.

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Radiological Dose Assessment Due to the Operation of Nuclear Facilities at KAERI Nuclear Site

  • Han, M.H.;Kim, E.H.;Hwang, W.T;Yeom, J.M.;Han, J.T.;Lee, Y.B.;Han, W.J.
    • Journal of Radiation Protection and Research
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    • v.28 no.3
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    • pp.247-254
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    • 2003
  • To prevent the potential health detriment to the public from radioactive effluents, radiological dose assessments due to the operation of nuclear facilities located at Korea Atomic Energy Research Institute (KAERI) site has been performed semiannually in compliance with the Minister of Science and Technology (MOST)'s Notice in Korea. Radiological dose assessment based on the new recommendation of the International Committee on Radiation Protection (ICRP-60) has been conducted since 1998. In this manuscript, a serial activities at KAERI site to meet the regulatory standards for routine releases of radioactive effluents are introduced and discussed including technical approaches. It is clear that each nuclear facility has been operated in compliance with regulatory standards. Furthermore, it is identified that the radiation induced health effects for residents around the site are neglectable.

Analysis on Operating Characteristics according to Applied Location of SFCL in a Power Transmission System (모의송전계통에서 고장전류 저감을 위한 초전도한류기 적용위치에 따른 동작특성 분석)

  • Lee, Hyeong-Jin;Park, Han-Min;Kim, Jin-Seok;Sung, In-Je;Lim, Sung-Hun;Kim, Jae-Chul
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1104-1105
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    • 2015
  • Recently, electric power demand increase due to the rapid industrial development. As a result, a power system has been expanded and fault currents are raised. Fault current is detriment effect on protective equipment. Superconducting fault current limiter(SFCL) is one of the solution to solve the fault current reduction. This paper analyzed operating characteristics according to applied location of SFCL in a transmission power system through the PSCAD/EMTDC simulation.

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Magnetic field imperfections of in-vacuum undulator on PLS-II beam dynamics

  • Chunjarean, Somjai;Hwan, Shin-Seung
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.359-359
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    • 2011
  • Many research applications in basic sciences and biology such as protein crystallography require hard x-rays in the range of 3-20 keV with high brightness. A medium energy storage ring as PLS-II with a beam energy of 3 GeV can meet such high photon energies. In-vacuum undulators (IVU) with a period length of 20 mm and a peak field of 0.97 T are used in the PLS-II ring to produce such X-rays in the fundamental or higher harmonics. Due to the many poles and high fields, insertion devices like wigglers and undulators have a significant impact on the stability of the electron beam with potential degradation of beam quality and life time. Therefore, nonlinear fields must be determined by measurement and evaluated as to their impact on beam stability. Specifically, transverse field roll-off can be a serious detriment to injection in top-up mode and must be corrected. We use magnetic field measurement data to evaluated beam stability by tracking particles using an explicit symplectic integrator in both, transverse and longitudinal planes.

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비아50 구조 구성품 정적강도 시험

  • Kang, Wang-Gu;Kim, Dong-Min;Lee, Jin-Woo;Yeom, Chan-Hong
    • Aerospace Engineering and Technology
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    • v.3 no.1
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    • pp.27-34
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    • 2004
  • Tail-wing, gondola and thrust motor mount(EMS) were built by carbon/glass fiber composites. Structural strength & stiffness was verified by specimen tests. Static strength tests for each structural components were conducted separately. Boundary conditions are specially designed for each components to simulate exact joint conditions. Tests shows no detriment deformation at 100% DLL and no failure at 150% DLL.

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Where's the Procedural Fluency?: U.S. Fifth Graders' Demonstration of the Standard Multiplication Algorithm

  • Colen, Yong S.;Colen, Jung
    • Research in Mathematical Education
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    • v.24 no.1
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    • pp.1-27
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    • 2021
  • For elementary school children, learning the standard multiplication algorithm with accuracy, clarity, consistency, and efficiency is a daunting task. Nonetheless, what should be our expectation in procedural fluency, for example, in finding the product of 25 and 37 among fifth grade students? Collectively, has the mathematics education community emphasized the value of conceptual understanding to the detriment of procedural fluency? In addition to examining these questions, we survey multiplication algorithms throughout history and in textbooks and reconceptualize the standard multiplication algorithm by using a new tool called the Multiplication Aid Template.

Interpretation of Estoppel Doctrine in the Letter of Credit Transaction : Comparison between UCP 500 and 95 UCC (신용장거래(信用狀去來)에서의 금반언법리(禁反言法理)에 관한 해석(解釋) - UCP 500 제13조, 제14조와 95 UCC 제5-108조의 비교를 중심으로 -)

  • Kim, Young-Hoon
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.12
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    • pp.429-460
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    • 1999
  • The letter of credit is quintessentially international. In the absence of international legal system, a private system based on banking practices has evolved, commanding the adherence of the international letter of credit community and providing the foundation of th reputation of this instrument. To maintain this international system, it is vital that international standard banking practice should not be subject to local interpretations that misconstrue or distort it. The UCP is a formulation of international standard banking practice. It is neither positive law nor a "contract term" in any traditional sense and its interpretation must be consonant with its character as a living repositary of international understanding in this field. As a result, the interpretation and application of specific articles of the UCP must be consistent with its evolving character and history and with the principles upon which sound letter of credit practice is predicated. This study, especially, focuses on article 13 and article 14 of the UCP500. Article 13(b) of UCP500 stipulates that banks will have a reasonable time, not to exceed seven days, to examine documents to determine whether they comply facially with the terms of the credit. The seven-day provision is not designed as a safe harbor, because the rule requires the issuer to act within a reasonable time. But, by virtue of the deletion of the preclusion rule in the document examination article in UCP500, however, seven days may evolve as something of a safe harbor, especially for banks that engage in strategic behavior. True, under UCP500 banks are supposed to examine documents within a reasonable time, but there are no consequences in UCP500 for a bank's violation of that duty. It is only in the next provision. Courts might read the preclusion more broadly than the literal reading mentioned here or might fashion a common-law preclusion rule that does not require a showing of detriment. Absent that kind of development, the change in the preclusion rule could have adverse effects on the beneficiary. The penalty, strict estoppel or strict preclusion, under UCP500 and 95UCC differs from the classic estoppel. The classic estoppel rule requires a beneficiary to show three elements. 1. conduct on the part of the issuer that leads the beneficiary to believe that nonconforming documents do conform; 2. reasonable reliance by the beneficiary; and 3. detriment from that reliance. But stict preclusion rule needs not detrimental reliance. This strict estoppel rule is quite strict, and some see it as a fitting pro-beneficiary rule to counterbalance the usually pro-issuer rule of strict compliance.

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Analysis of Global Food Market and Food-Energy Price Links: Based on System Dynamics Approach

  • Kim, Gyu-Rim
    • Korean System Dynamics Review
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    • v.10 no.3
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    • pp.105-124
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    • 2009
  • The situation of the global food markets has been being rapidly restructured and entering on a new phase by new dynamic and driving forces. The factors such as economic growth and income increase, high energy price, globalization, urbanization, and global climate change are transforming patterns of food consumption, production, and markets. The prices and markets of world food and energy are getting increasingly linked each other. Food and fuel are the global dilemma issues associated with the risk of diverting farmland or of consuming cereals for biofuel production in detriment of the cereals supply to the global food markets. An estimated 100 million tons of grain per year are being redirected from food to fuel. Therefore, the objectives of this study are as follows: Firstly, the study examines situations of the world food and energy resources, analyzes the trends of prices of the crude oil and biofuel, and formulates the food-energy links mechanism. Secondly, the study builds a simulation model, based on system dynamics approach, for not only analyzing the global cereals market and energy market but also forecasting the global production, consumption, and stock of those markets by 2030 in the future. The model of this study consists of four sectors, i.e., world population dynamics sector, global food market dynamics sector, global energy market dynamics sector, scenario sector of world economic growth and oil price.

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HPLC Determination of Diltiazem and Deacetyldiltiazem in Rat Plasma (HPLC를 이용한 랫트 혈장중의 딜타아젬 및 데아세틸딜티아젬의 정량)

  • Lee, Yong-Hee;Shim, Chang-Koo;Lee, Min-Hwa;Kim, Shin-Keun
    • Journal of Pharmaceutical Investigation
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    • v.22 no.4
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    • pp.317-321
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    • 1992
  • A high-performance liquid chromatographic (HPLC) method was developed for the determination of diltiazem (DTZ) and its major metabolite, deacetyldiltiazem (DAD), in rat plasma. DTZ, DAD and imipramine, the internal standard, were selectively fractionated from plasma on a $C_{18}$ reversedphase column $({\mu}-Bondapak,\;10\;{\mu}m\;silica,\;300{\times}3.9\;mm\;ID)$. The composition of the mobile phase was methanol: acetonitrile: 0.04 M ammonium bromide: triethylamine (40:24:36:0.06 in volume). The pH of the mobile phase of their method was lowered to 6.4. The eluents from the column were detected for DTZ and DAD using a UV detector at 237 nm. The recovery was >85% for DTZ and DAD, and average intra-day and inter-day coefficients of variation were <6% for DTZ and DAD at the concentration ranges of 20-1000 ng/ml. Detection limit of DTZ and DAD in plasma was 20 ng/ml with signal-to-noise ratio of 3. This method would be applicable to practical pharmacokinetic studies without detriment to the HPLC column.

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