• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.10a
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• pp.1154-1158
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• 1995

Electrical Discharge Machining, with its ability to machine hard metals and tough shapes has become a very desirable process. In the past few years, Electrical Discharge Machining (EDM) has been solidly established in tool-room and large-scale production. However, in spite of its indispensability in many areas of metal removal applications, the theoretical basis of EDM process is yet to be established. More importantly, the information regarding essential technology parameters such as machining rate and resulting surface roughness integrity, has not been raised to the level of a general technical science. The paper presents a method, which can be determining approprate machining parameters for the given parameters such as electrode wear and surface roughness based on machining guideline utilizing neural networks.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11b
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• pp.86-91
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• 2002

The regression analysis in the six sigma process is used to reduce the vibration of an electric grinder. The vibration characteristics and the contribution of each part to overall vibration of the electric grinder is investigated through various vibration measurements and frequency analysis for the assembled and disassembled one. Then the application of the regression analysis finds out that the rotating components of the armature have more severe contributions to the overall vibration than the frequency components of the fan or the gear part, which is decided with higher value of the coefficient of determination. The unbalance and looseness of the armature and the fan are tested again by the regression analysis in order to decide how much unbalance or looseness should be reduced for the predetermined goal of vibration level of the electric grinder. These results show that the regression analysis can be a valuable tool in production line to decide where and how much faults needs to be adjusted for the reduction of vibration and noise.

• Toxicological Research
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• v.17
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• pp.197-199
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• 2001

Enhancement of antigen-specific IgE is a hallmark of allergic hyperresponsiveness, therefore it is necessary to adopt or develop a highly sensitive and specific assay for determination of allergen-specific IgE levels in vivo. In this presentation, we introduce an ELISA (enzyme linked immunosorbent assay) system developed to measure the levels of chicken egg ovalbumin (OVA)-specific IgE in serum. The ELISA method uses a commercially available purified rat anti-mouse IgE as a capture Ab and biotinylated OVA as a detection reagent. Avidin-peroxidase with its substrate is used for color development resulting in optical density measurement at 405 nm. The ELISA system produces a highly sensitive dose-response relation-ship between optical density levels and the dilution titer of the OVA-IgE standard serum but no cross-reaction with unrelated IgE or IgG. It is believed that the system is an Efficient tool to delineate an adjuvant effect of environmental pollutants on development of asthmatic and atopic responses.

• Mass Spectrometry Letters
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• v.6 no.2
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• pp.31-37
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• 2015

Phosphorylation upon protein is well known to a key regulator that implicates in modulating many cellular processes like growth, migration, and differentiation. Up to date, grafting of multidimensional separation techniques onto advanced mass spectrometry (MS) has emerged as a promising tool for figuring out the biological functions of phosphorylation in a cell. However, advanced MS-based phosphoproteomics is still challenging, due to its intrinsic issues, i.e., low stoichiometry, less susceptibility in positive ion mode, and low abundance in biological sample. To overcome these bottlenecks, diverse techniques (e.g., SCX, HILIC, ERLIC, IMAC, TiO₂, etc.) are continuously developed for on-/off-line enrichment of phosphorylated protein (or peptide) from biological samples, thereby helping qualitative/quantitative determination of phosphorylated protein and its phosphorylated sites. In this review, we introduce to the overall views of enrichment tools that are universally used to selectively isolate targeted phosphorylated protein (or peptide) from ordinary ones before MS-based phospoproteomic analysis.

• IE interfaces
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• v.5 no.2
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• pp.53-74
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• 1992

In order to design an FMS(Flexible Manufacturing System), an effective design tool is necessary for selecting and anlayzing the complex interacting factors of a manufacturing system. Considering most of the previous researches have been focused on evaluating the designed FMS, development of an integrated FMS designing system is needed for performing the design task such as machine selection and layout determination as well as the evaluation task of the designed FMS. In this paper, we developed a prototype of such a system called the intelligent FMS designer based on the techniques of Expert System and Simulation. By using this designing system, possible design alternatives can be analyzed and appropriate manufacturing capacity can be estimated at the designing stage. Various operating characteristics of the designed FMS can be also predicted before it is implemented. Eventually a suitable design alternative can be provided with cost details within relatively short time period. To demonstrate the performance and effectiveness of the designer, a simple example is tested. The results show a great potential for automating design processes of an FMS.

• Clinical and Experimental Pediatrics
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• v.52 no.9
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• pp.964-970
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• 2009

Neonatal seizures are generally not only brief and subtle but also not easily recognized and are usually untreated. In sick neonates, seizures are frequently not manifested clinically but are detected only by electroencephalography (subclinical EEG seizures). This phenomenon of electroclinical dissociation is fairly common in neonates. On the other hand, neonates frequently show clinical behaviors such as stiffening, apnea, or autonomic manifestations that mimic seizures, which is usually associated with underlying encephalopathy and non-epileptic seizures. Therefore, it might be difficult to confirm the diagnosis of neonatal seizures. Early recognition of neonatal seizures is important to minimize poor neurodevelopmental outcomes, including cognitive, behavioral, and learning disabilities, as well as the development of postnatal epilepsy. EEG is a reliable tool in the determination of neonatal seizures. Continuous EEG monitoring is essential for the identification of seizures, evaluation of treatment efficacy, and prediction of the neurodevelopmental outcome. However, there is not yet a wide consensus on the optimal "standard" lead montage for the continuous EEG monitoring.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.6
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• pp.169-176
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• 2012

This study describes the estimation of upstream ungauged watershed streamflow using downstream discharge data. For downstream Dongchon (DC) and upstream Kumho (KH) water level stations in Kumho river basin ($2,087.9km^2$), three methods of Soil and Water Assessment Tool (SWAT) modeling, drainage-area ratio method and regional regression equation were evaluated. The SWAT was calibrated at DC with the determination coefficient ($R^2$) of 0.70 and validated at KH with $R^2$ of 0.60. The drainage-area ratio method showed $R^2$ of 0.93. For the regional regression, the watershed area, average slope, and stream length were used as variables. Using the derived equation at DC, the KH could estimate the flow with maximum 41.2 % error for the observed streamflow.

• Journal of the Korean Magnetic Resonance Society
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• v.5 no.1
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• pp.13-18
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• 2001

Natural alpha radiation produced a stable defect center to certain minerals. Electron Paramagnetic Resonance(EPR) spectroscopy is a powerful tool f3r quantifying this defect center. EPR method has been applied to trace alpha-radiation effect around the uranium ore deposit. The results show that EPR technique can be used to measure rapidly and nondestructively the defect center produced by natural alpha radiation. In general, a good correlation was achieved between defect center concentration and actinide elements(U, Th). These results imply that the concentration of defect center is dependent on the alpha radiation dose over long time scale.

• Journal of information and communication convergence engineering
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• v.10 no.1
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• pp.66-70
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• 2012

Conformal mapping has been a familiar tool of science and engineering for generations. Determination of a conformal map from the unit disk onto the Jordan region is reduced to solving the Theodorsen equation, which is an integral equation for boundary correspondence functions. There are many methods for solving the Theodorsen equation. It is the goal of numerical conformal mapping to find methods that are at once fast, accurate, and reliable. In this paper, we analyze Niethammer’s solution based on successive over-relaxation (SOR) iteration and Wegmann’s solution based on Newton iteration, and compare them to determine which one is more effective. Through several numerical experiments with these two methods, we can see that Niethammer’s method is more effective than Wegmann’s when the degree of the problem is low and Wegmann’s method is more effective than Niethammer’s when the degree of the problem is high.

• KIEAE Journal
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• v.5 no.1
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• pp.35-42
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• 2005

The primary concerns of recreation plan are to provide visitors with quality of recreational experience and to protect of recreation resources. The quality of recreational experience is often defined in terms of social carrying capacity. The carrying capacity is revealed as perceived crowding. In this respects, measuring perceived crowding is useful tool of social carrying capacity determination. This study is to test the structural equation model that includes variables affecting perceived crowding. Through an on-site questionnaire survey, 467 visitors on Naejangsan national park were collected. The results of the study are follows. The encounter level on facility area is higher evaluated as crowding factor than other area in the park. It can be concluded that visitor perceived crowding when facility area situates high density use level rather than other areas expose high density use level. In the path analysis, the input variables(attitude, experience, encounter level) on the structural equation model affect significantly on perceived crowding. Especially, the attitude on the park management polocy is the most affecting factor on perceived crowding.