• Journal of Korean Society for Quality Management
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• v.50 no.3
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• pp.373-386
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• 2022

Purpose: This study proposes the application of Six Sigma management innovation method for more systematically enhanced execution of Quality by Design (QbD) activities. QbD requires a deeper understanding of the product and process at the design and development stage of the drug, and it is very important to ensure that no fault is fundamentally generated through thorough process control. Methods: Analyzing the background and specific procedures of quality improvement based on the drug design basis, and analyzing the key contents of each step, we have differentated and common points from the 6 Sigma methodology. We propose a new model of Six Sigma management innovation method suitable for pharmaceutical industry. Results: Regulatory agencies are demanding results from statistical analysis as a scientific basis in developing medicines to treat human life through quality improvement activities based on drug design. By utilizing the education system to improve the statistical analysis capacity in the Six Sigma activities and operating the 6 Sigma Belt system in conjunction, it helped systematically strengthen the execution power of quality improvement activities based on pharmaceutical design based on the members of the pharmaceutical industry. Conclusion: By using QbD Six Sigma, which combines quality enhancement based on pharmaceutical design basis and Six Sigma methodology suitable for pharmaceutical industry, it is possible to obtain satisfactory results both by pharmaceutical companies and regulators by using appropriate statistical analysis methods for preparing scientific evidence data required by regulatory.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.11a
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• pp.593-594
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• 2008

The purpose of this study is to review and to suggest improvement concerning floor impact noise section of the housing performance grading indication system. After a result, the main improvement is to resolve the discrepancies in the rules or regulations such as design specification(standard floor system) or design performance(accredited floor system) and as-built performance like 58 dB.

• Journal of the Korea Safety Management & Science
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• v.2 no.3
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• pp.141-150
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• 2000

This study aim is analysis device development for design of experiment with calcium chloride relation used a hardener to search cause of product crack, product reliability improvement building data-base program for computer system of mixture rate, product improvement, and new product development.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1712-1717
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• 2007

This paper presents a derating design approach for reliability improvement of an aluminum electrolytic capacitor. The capacitor, usually mounted in a printed circuit board, is used to stabilize the circuit. The main failure mechanism of interest is dry-up of the electrolyte that is mainly caused by two stresses-temperature and voltage. The lifetime under these stresses is modeled as a function of these stresses and time using accelerated life testing. Quantitative variation in the lifetime, according to variations in these stresses, is investigated to perform the derating design of the capacitor so that the stress levels are selected to achieve required reliability measures for reliability improvement. Moreover, sensitivity analysis shows which stress would be a more important factor determining the lifetime.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.389-394
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• 1996

The product-user interface for consumer electronic products became complex due to the increased variety of functions corresponding to consumer needs. In this study, three types fo design improvement of the menu interface for a video cassette recorder is studied. Three modifications to an existing menu interface was designed using the semantic, the syntactic and the lexical design factors. A series of the validation experiments was performed to test the effect of the three types of task modifications. The results showed that performance time, number of errors and learning effect were improved for all task modification. It also showed that the performance improvement effect of the semantic factors was 8.8%, that of the syntactic factors was 5.9% and that of the lexical factors was 5.6% respectively. It was found out that the performance improvement effect of the semantic design factors were relatively more significant than the syntactic and the lexical design factors.

• Journal of the Korean Geotechnical Society
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• v.16 no.2
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• pp.79-89
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• 2000

The application of stabilization method has increased because of short construction periods, no environmental problems with dumped and replaced soil, assurance of required strength and economical effect with mid to small size construction. The unconfined and triaxial(UU-condition) compression tests were executed with each mixing sample for the study of the improvement effects and the effect of design-parameters by the stabilization methods. Three typical stabilizers, which are representative in Korea, were applied in this study, and three common soils(very soft clay, general weathered soil, common clay), which are common in Korea, were used in this study. In this study, the effect of engineering factors(soils, stabilizers and water contents, etc.) which are important parameters for the improvement effects of mixed ground by stabilizers, was analyzed. As results, the tendencies of design-parameters(unconfined compression strength, deformation modulus and strength parameter) are presented and the criteria of the application of stabilization methods are suggested.

• Proceedings of the KIEE Conference
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• 2006.07b
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• pp.777-778
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• 2006

This paper deals with the optimum rotor design approach about the multi-layer design of the buried magnets in an Interior Permanent Magnet Synchronous Motor (IPMSM), on the efficiency improvement by using Response Surface Methodology (RSM). In the multi-layer design of the prototype 15kw IPMSM, the constant amount of buried PM is split from the single-layer into double-layer design for improving the efficiency characteristics. The optimum double-layer rotor structure is built with the help of RSM analysis. The improvement of IPMSM efficiency is verified by the Finite Element Method (FEM) results comparison with the prototype single-layer IPMSM.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.629-630
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• 2010

• International Journal of Aeronautical and Space Sciences
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• v.8 no.2
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• pp.28-36
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• 2007

A multi-objective design exploration for a three-element airfoil consisted of a slat, a main wing, and a flap was carried out. The lift curve improvement is important to design high-lift system, thus design has to be performed with considered multi-angle. The objective functions considered here are to maximize the lift coefficient at landing and near stall conditions simultaneously. Kriging surrogate model which was constructed based on several sample designs is introduced. The solution space was explored based on the maximization of Expected Improvement (EI) value corresponding to objective functions on the Krigingmodels. The improvement of the model and the exploration of the optimum can be advanced at the same time by maximizing EI value. In this study, a total of 90 sample points are evaluated using the Reynolds averaged Navier-Stokes simulation(RANS) for the construction of the Kriging model. In order to obtain the information of the design space, two data mining techniques are applied to design result. One is functional Analysis of Variance(ANOVA) which can show quantitative information and the other is Self-Organizing Map(SOM) which can show qualitative information.

• Journal of Navigation and Port Research
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• v.44 no.1
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• pp.1-9
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• 2020

The purpose of this study was to investigate user satisfaction by identifying the problems and suggesting Improvement plans of interior design in the accommodation area of Ro-Pax ships. First, the characteristics of Ro-P ax ships' accommodation area through previous studies and references, and then a field survey was conducted on seven kinds of Ro-Pax ships. Based on the field study, a questionnaire survey was administered targeting 38 experts involved in passenger ships who indicated that public facilities were the most unsatisfactory of interior design in accommodation areas. As a result of Multiple Linear Regression Analysis, the satisfaction of color showed the highest influence on user satisfaction in accommodation areas, and required the standard of the interior design in accommodation areas. The suggested results of research were the types and layout of public facilities, improvement of color design, provision of interior design standard for accommodation areas, and improvement plans for interior design of Ro-Pax ships.