• Title/Summary/Keyword: Design department

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Statistical Analysis of Bioequivalence Study in $3{\times}2$ Crossover Design ($3{\times}2$ 교차설계법에서 생물학적 동등성 시험의 통계분석)

  • Park, Sang-Gue;Kim, Jeong-Il;Chae, Sung-San;Ko, Seoung-Gon;Oh, Hyun-Sook;Yang, Wan-Youn;Kim, Dong-Sup;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.28 no.4
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    • pp.231-239
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    • 1998
  • A $3{\times}2$ crossover design is considered for the bioequivalence of two test formulations with a control. It could be considered as a better choice over $3{\times}3$ crossover design because of the cost and experimental duration. Oh et al.(1998) derived $3{\times}2$ crossover design and discussed its benefits over the typical crossover designs. We consider here the statistical models for $3{\times}2$ crossover design and show its statistical properties. The statistical procedures for the bioequivalence in $3{\times}2$ crossover design are shown through an example and the results are summarized by satisfying the 3 standards that proposed by the Korea Food and Drug Administration Guidelines for Bioequivalence.

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Aircraft derivative design optimization considering global sensitivity and uncertainty of analysis models

  • Park, Hyeong-Uk;Chung, Joon;Lee, Jae-Woo
    • International Journal of Aeronautical and Space Sciences
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    • v.17 no.2
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    • pp.268-283
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    • 2016
  • Aircraft manufacturing companies have to consider multiple derivatives to satisfy various market requirements. They modify or extend an existing aircraft to meet new market demands while keeping the development time and cost to a minimum. Many researchers have studied the derivative design process, but these research efforts consider baseline and derivative designs together, while using the whole set of design variables. Therefore, an efficient process that can reduce cost and time for aircraft derivative design is needed. In this research, a more efficient design process is proposed which obtains global changes from local changes in aircraft design in order to develop aircraft derivatives efficiently. Sensitivity analysis was introduced to remove unnecessary design variables that have a low impact on the objective function. This prevented wasting computational effort and time on low priority variables for design requirements and objectives. Additionally, uncertainty from the fidelity of analysis tools was considered in design optimization to increase the probability of optimization results. The Reliability Based Design Optimization (RBDO) and Possibility Based Design Optimization (PBDO) methods were proposed to handle the uncertainty in aircraft conceptual design optimization. In this paper, Collaborative Optimization (CO) based framework with RBDO and PBDO was implemented to consider uncertainty. The proposed method was applied for civil jet aircraft derivative design that increases cruise range and the number of passengers. The proposed process provided deterministic design optimization, RBDO, and PBDO results for given requirements.

Design and manufacturing of progressive die for Test Work (테스트워크 순차이송금형 설계 및 제작)

  • Kim, Young-Cheon;Sim, Eung-Chul;Lee, Hyun-Sang;Hong, Yong-Soo;Chung, Wan-Jin
    • Design & Manufacturing
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    • v.6 no.2
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    • pp.17-23
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    • 2012
  • In April 2010, the die and mould grand prix for university student was held in Osaka as a special event of Inter Mold Japan. The students from Korea, China, and Japan participated to demonstrate the design and manufacturing skill of die and mould. Based on the given product drawing of Test Work, progressive die should be designed and manufactured. Also, production of Test Work should be carried out. This study had been conducted to participate in the grand prix and to learn practical knowledge and experience from real die design and making. Test Work is made of SPCC and includes piercing, blanking, deep drawing and burring. From the analysis of product drawing, process planning and die design was carried out. Progressive die for Test Work was manufactured using CNC milling, grinding, wire-cutting and polishing. The production was successfully completed using mechanical press and product showed very good accuracy satisfying all dimensional tolerances.

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Improved transient response design of MRACS

  • Oki, toshitaka;Shin, Seungin;Tanaka, Kanya;Shimizu, Akira;Shibata, Satoru
    • 제어로봇시스템학회:학술대회논문집
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    • 1994.10a
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    • pp.488-493
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    • 1994
  • The global stability of model reference adaptive control system (MRACS) in the ideal case was resolved in the 1980's. Hoever the improvement of the transient, behaviour of MRACS has not been discussed sufficiently even in the ideal case. Only a few attempts have so far been made at the application of MRACS to the practical systems in contrast to the theoretical systematization. Therefore, when we consider the practical usage of MRACS it is necessary to develop an improved design scheme with respect to transient behaviour. In this paper, we propose two design schemes improving transient behaviour of MRACS by mollifying the input synthesis in the conventional design scheme of MRACS. We present a design scheme of MRACS in which we utilize the design approach of variable structure system(VSS). After describing the above design scheme, we also propose the improved design scheme in which we introduce the dead-zone decided by the magnitude of the output-error between the plant and the reference model. The effectiveness of the proposed two design schemes are shown through computer simulations. As the results, by using these methods, the convergence of the transient response is greatly improved in comparison with the conventional one.

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Affective Evaluation of Interior Design of Commercial Cars using 3D Images

  • Park, Kunwoo;Park, Jaekyu;Kim, Sungmin;Choe, Jaeho;Jung, Eui S.
    • Journal of the Ergonomics Society of Korea
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    • v.33 no.6
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    • pp.515-532
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    • 2014
  • Objective: The purpose of this study is to define consumers' affection on the interior design of commercial cars in terms of its design factors: color, embossing and gloss as independent factors. Background: Existing affective studies related to interior of vehicle focus on just sedans. However, there is no affective study about the interior of commercial cars. In addition, it is hard to change levels to which manufactures want. Method: Representative design factors were drawn using ANOVA and SNK analysis and definitive affective vocabularies were drawn using factor analysis. Furthermore, the results of 3D experiment were analyzed using ANOVA and LSD analysis. 3D images for the experiment were made using 3D max program. The experiment revealed that consumers discerned the differences in levels of each design factor and affective vocabulary. Results: The ANOVA revealed that beige color "A" type and non-gloss were the most preferred design in terms of the affective vocabularies and total preference. Conclusion: The result of the experiment may help manufactures to design the interior of commercial cars in the near future. Furthermore, the ANOVA result of affective vocabularies evaluation is expected to suggest a meaningful guideline. Application: The study results may be utilized as a guideline for interior design of commercial cars.

Brand Fandom Dynamic Analysis Framework based on Customer Data in Online Communities

  • Yu Cheng;Sangwoo Park;Inseop Lee;Changryong Kim;Sanghun Sul
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.17 no.8
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    • pp.2222-2240
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    • 2023
  • Brand fandom refers to a collection of consumers with strong emotions toward a brand. Studying the dynamics of brand fandom can help brands understand which services or strategies influence their consumers to become a part of brand fandom. However, existing literature on fandom in the last three decades has mainly used qualitative methods, and there is still a lack of research on fandom using quantitative methods. Specifically, previous studies lack a framework for locating fandoms from online textual data and analyzing their dynamics. This study proposes a framework for exploring brand fandom dynamics based on online textual data. This framework consists of four phases based on the design thinking model: Preparing Data, Defining Fandom Categories, Generating Fandom Dynamics, and Analyzing Fandom Dynamics. This framework uses techniques such as social network analysis and process mining, combined with brand personality theory. We demonstrate the applicability of this framework using case studies of two Korean home appliance brands. The dataset contains 14,593 posts by consumers in 374 online communities. The results show that the proposed framework can analyze brand fandom dynamics using textual customer data. Our study contributes to the interdisciplinary research at the intersection of data-driven service design and consumer culture quantification.

Development of Instructional Design Model and Checklist for AI Education (인공지능교육을 위한 수업설계모형 및 체크리스트 개발)

  • Kim, So-yeon;Cho, Seo-yeon;Kang, Shinchun;Lee, Eun-sang;Im, Tami
    • Journal of Engineering Education Research
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    • v.25 no.6
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    • pp.81-92
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    • 2022
  • The purpose of this paper was to develop an instructional design model and checklist for AI education. Literature review was conducted to derive the structure of the instructional design model. And delphi survey was conducted twice to revise and improve the elements & items of the instructional design model and checklist and to confirm the content validity of both instructional design model and the checklist. As a result, an instructional design model consisting of three main steps(Analysis - Design & Development - Implementation & Evaluation) was suggested with a detail checklist which explained what teachers need to do in each step of this instructional development model when they prepare AI education using this instructional design model. Limitations and suggestions for further studies were presented at the end of this paper.

Analysis of Improvement Methods of Safety Management Guidelines with Design for Safety

  • Kim, Minjung;Park, Moonseo;Lee, hyun-soo;Lee, Dowan;Lee, seul bi
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.602-603
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    • 2015
  • Despite all efforts to reduce construction disaster, construction site accident rate has steadily increased in Korea since 2008. As a different approach from traditional research, there is a growing issue about design for safety concept to prevent construction disaster. The notion is that construction worker's safety need to be considered at design phase, not only at construction phase. Globally, the notion has been noted that to improve the safety of the worker and used in practice. However, in Korea, most of safety management guidelines are limited to construction phase. From recent statistics, only 1.4 percent of designer feel responsible for safety accident at construction site. In this circumstance, this research find out safety guidelines through literatures reviews and practical experience of safety management in other country which apply design for safety concept. Selected guidelines are verified by survey which is evaluated with risk, function, cost, time and aesthetic view categories. Through the survey, define guidelines which could be effectively applied in Korea. By using proposed safety guidelines for design phase, preventing construction accident and improving designer's recognition of safety issue at design phase are expected.

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Selection and Analysis of Genomic Sequence-Derived RNA Motifs Binding to C5 Protein

  • Kim, Kwang-sun;Ryoo, Hye-jin;Lee, June-Hyung;Kim, Mee-hyun;Kim, Tae-yeon;Kim, Yool;Han, Kook;Lee, Seol-Hoon;Lee, Young-hoon
    • Bulletin of the Korean Chemical Society
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    • v.27 no.5
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    • pp.699-704
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    • 2006
  • Escherichia coli RNase P is a ribonucleoprotein composed of M1 RNA and C5 protein. Previously, analysis of RNA aptamers selected for C5 protein from a synthetic RNA library showed that C5 protein could bind various RNA molecules as an RNA binding protein. In this study, we searched cellular RNA motifs that could be recognized by C5 protein by a genomic SELEX approach. We found various C5 protein-binding RNA motifs derived from E. coli genomic sequences. Our results suggest that C5 protein interacts with various cellular RNA species in addition to M1 RNA.