• Journal of Korean Ophthalmic Optics Society
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• v.18 no.2
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• pp.107-115
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• 2013

Purpose: This study was conducted to investigate the change of soft contact lens parameters after eyeliner deposition and compare the cleaning efficiency and the recovery rate of lens parameters by different cleaning methods. Methods: The eyeliner was deposited on three types of soft contact lenses made of different materials for 1 hour, 4 hours and 6 hours and those lenses were washed by the eyeglasses ultrasonic cleaning and by hands. The changes in visible light transmittance, diameter and surface of those lenses were compared before and after cleaning of the lens. Results: The visible light transmittance of soft contact lenses decreased along with the deposition time of eyeliner. The patterns of the eyeliner deposition on soft contact lens appeared differently depending on the physical properties of the lens material. Thus, the largest eyeliner deposition was found on narafilcon A lens. The diameters of hilafilcon B and etafilcon A lenses were decreased, however, the diameter of narafilcon A lens was increased. The cleaning efficiency of the eyeliner deposition was greater with the multipurpose solution by hands than with the eyeglasses ultrasonic cleaner. However, the recovery of lens parameters such as the lens diameter, visible light transmittance and lens surface due to the eyeliner deposition to its original state was limited. Conclusions: From these results, it is suggested to minimize eye makeup when wearing soft contact lens. Furthermore, the reduced wearing time and shorter cycle of lens replacement may be needed by considering a change of lens parameter when the repeat eye makeup is applied.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.1
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• pp.19-25
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• 2013

Purpose: The degree of the pupil covered with tinted region of circle soft contact lens was determined according to the illuminant conditions in everyday life and the change of visual acuity by its covering was further investigated. Methods: The circle contact lens having the non-tinted area of 6.2 mm in the center of the lens was applied on 82 eyes in their 20s and their minimum separable visual acuity and minimum legible visual acuity were determined under the luminances of 50 and 370 lux. Results: The covering of pupil was not found when wearing circle contact lens under 370 lux, however, some pupil covering ranged from 0.40 to 1.70 mm was observed in all subjects under 50 lux. The minimum separable visual acuity and minimum legible visual acuity were significantly decreased by the wearing of circle contact lens under 50 lux and the correlation between the larger pupil size of subjects and more decrease of visual acuity was observed. Furthermore, the decrease of minimum separable visual acuity was larger than the case of minimum legible visual acuity indicating that minimum separable visual acuity was largely affected by the covering of pupil. Conclusions: The consideration is necessary for the lens wearers and the manufacturers since the wearing circle contact lens in low-light indoor or nighttime activities may affect directly visual acuity.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.171-177
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• 2014

Purpose: The present study was conducted to investigate whether the elution of the dyes from the circle contact lenses existed or not when rubbed with cotton swab. Methods: The change of lens surface was observed by scanning electron microscope when a total of seven kinds of circle contact lens were rubbed with cotton swab, and the dye elution was further compared when the lenses were soaked in multi-purpose solution in $20^{\circ}C$ and $36.5^{\circ}C$ for a week. Results: Five of a total of 7 circle contact lenses showed the dye elution from the front or the back surface of the lens when rubbed with cotton swabs, and existence of dye elution was varied depending on the type of contact lenses and different at the front and back surface even in the same lens. The tear-off of the pigmented portion by the rubbing was found through scanning electron microscopic observation when the dye elution existed. However, the dye was not eluted when the circle contact lenses was soaked in a multi-purpose solution in $20^{\circ}C$ or $36.5^{\circ}C$ for a week. Ingredient of colorant was not provided by the manufacturers in more than 50% of the circle contact lenses investigated for this study and the basic information such as the pigmentation method was provided inappropriately. Conclusions: In this study, the result was the dye elution from circle contact lenses was obtained when a physical force is applied thus, it may appear to contribute the development of circle contact lenses and safety of lens wear.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.2
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• pp.137-146
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• 2016

Purpose: The relationship between retinal conditions such as macular thickness and retinal volume of the eyes with central serous chorioretinopathy(CSC) and visual acuity was investigated. Methods: A total of 136 eyes from 78 subjects was divided into 5 groups: CSC eyes under treatment and its asymptomatic contralateral eyes, fully cured CSC eyes after the diagnosis and its contralateral, and normal eyes. Their uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), retinal thickness and retinal volume were further examined. Results: All of UCVA, BCVA, retinal thickness and retinal volume of CSC eyes under treatment were significantly different from those of asymptomatic contralateral eyes, fully cured CSC eyes and normal eyes. BCVA of the asymptomatic contralateral eyes was not significantly different from it of normal eyes, however, its retinal thickness and volume were significantly different from those of normal eyes. Increased degree of retinal volume along with the increase of retinal volume was greater in CSC eyes and its asymptomatic contralateral eyes, fully cured CSC eyes and its contralateral eyes than normal eyes. Conclusions: From the present study, it was revealed that the retinal thickness and volume of asymptomatic contralateral eyes of CSC increase as well as CSC eyes, and the change of BCVA due to CSC occurs only when the retinal thickness and volume increase in some extent.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.1
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• pp.75-81
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• 2015

Purpose: The present study was conducted to investigate whether the changes in structure and activity of antioxidative enzymes, superoxide dismutase(SOD) and catalase(CAT) present in the eyes appeared when they were repeatedly exposed to UV-A, and reveal the correlation of these changes. Methods: Each enzyme solution was prepared from the standardized SOD and CAT, and repeatedly exposed to UV-A of 365 min under the condition of 30 minutes, 1 hour and 2 hours a day over 1, 2, 3, 4 and 5 days. Structural denaturation of SOD and CAT induced by repeat UV-A irradiation was confirmed by the electrophoretic analysis, and their enzyme activity was determined by the colorimetric assay using the proper assay kit. Results: SOD exposed repeatedly to UV-A showed the polymerization pattern through the electrophoretic analysis when it was repeatedly exposed under the condition of at least 1 hour a day however, the change of its activity was found to be less than 12%. On the other hand, CAT repeatedly exposed to UV-A showed reduced size of the electrophoretic band which indicated a structure denaturation and its activity was significantly decreased. In the case of that the repeat exposure time was longer, CAT activity was completely lost even though some enzyme band was shown in the electrphoretic analysis. Conclusions: From these results, it was revealed that the degree and pattern in structural denaturation of antioxidative enzymes differently appeared according to the type of enzyme, and the degree of structural denaturation was not always consistent with the reduction in enzyme activity.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.2
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• pp.177-184
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• 2012

Purpose: In this study, the effect of the eye movement direction on visual function related to accommodation was investigated when playing computer games for a certain period of time. Methods: Total 60 subjects in 20s who had the visual acuity of 1.0 or higher without any ocular disease and accommodative dysfunction were asked to play computer games separately in horizontal and vertical directions for 40 and 90 minutes and then measured their accommodative amplitude, accommodative facility, accommodative lag and relative accommodations. Thevisual function when not doing the computer game was regarded as a control value, and further compared and analyzed. Results: The accommodative amplitude, accommodative facility, accommodative lag and relative accommodations showed the tendency of decrease after the computer game for 40 minutes, and more reduced values of the visual functions were shown when the computer game extended up to 90 minutes except positive relative accommodation. Positive relative accommodation had a tendency to increase slightly after the computer game for 90 minutes. Meanwhile, the change of the visual functions was primarily influenced by the eye movement in horizontal direction rather than by the eye movement in vertical direction during computer game when analyzed by the direction of eye movement. Conclusions: Over all accommodative functions tended to decrease with the extended VDT working time by computer game, and the frequent eye movement in horizontal direction during VDT tasks could be the main cause of eyestrain since the eye movement in horizontal direction rather than vertical direction significantly affected the change of accommodative function.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.59-67
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• 2014

Purpose: The present study was aimed to compare the results of disinfection efficacy tested by membrane filtration method with dilution-neutralization method to develop the standard methods for evaluating disinfection efficacy of contact lens care products and to provide the result of disinfection efficacy of commercially available contact lens care products in domestic market. Methods: The results of disinfection efficacy against Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Candida albicans evaluated by membrane filtration method as a FDA standard and dilution-neutralization method as newly being a KFDA standard were compared and the disinfection efficacy of 16 multi-purpose solutions was further evaluated. Results: The disinfectants and contact lens care products having strong disinfection efficacy showed same results in both membrane filtration method and dilution-neutralization method. In case of contact lens care products having weak disinfection efficacy, the number of micro-organisms was not able to count since the colony was aggregated when evaluated by membrane filtration method. However, the number of micro-organisms was able to exactly count when evaluated by dilution-neutralization method. In addition, some commercially available contact lens care products did not meet disinfection standard and especially, their disinfection effect was often weak against Serratia marcescen and Candida albicans. Conclusions: It is concluded that dilution-neutralization method will be useful to evaluate disinfection efficacy since it is possible to count micro-organisms more precisely even with small amount of sample and check the results faster compared with membrane filtration method.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.3
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• pp.383-387
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• 2014

Purpose: To investigate the effect of corneal unique shape to changes of refractive full corrections when pupil size changes. Methods: Subjective refraction for monocular full correction was performed to 30 subjects ($23.33{\pm}1.78$ of age, 60 eyes) in two room conditions, 760 lx and 2 lx, respectively. Pupillary diameter was measured in two conditions and the change pattern was analyzed using a peak data of corneal topography. Results: Pupillary diameter was 3.74~4.00 mm in 760 lx and 5.52~5.90 mm in 2 lx. By comparison with refractive data in 760 lx, those data in 2 lx was changed as follows: more (-) spherical power of 17 eyes (28.3%), more (+) spherical power of 10 eyes (17.7%), more (-) cylinderical power of 17 eyes (28.8%), less (-) cylinderical power of 9 eyes (15.3%), and astigmatic axis rotation of 36 eyes (62.1%). From peak data of corneal topography, the changing pattern of two principal meridians was classified into 4 types. Conclusions: Expansion of the corneal refractive surface accompanied with pupillary dilation may be a main factor that effects the changing a values of subjective refraction because of unique corneal shape. Therefore, subjective refraction should be performed under the nearest lighting condition to a main living environment.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.195-200
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• 2015

Purpose: This study was performed in order to figure out the influence of illumination on visual function. Methods: 40 adults (male 21, female 19) of average age $23.93{\pm}1.59$ years were participated in this study. The test chart surface illumination was adjusted to 5, 50, 200, 500 and 800 lx, and then amplitude of accommodation, near point of convergence, far and near distance phoria, far and near distance fusional vergence, relative accommodation, and accommodation lag were measured at each illumination condition. Results: As illumination intensity of test chart was reduced, amplitude of accommodation was significantly decreased (p<0.05), accommodation lag was also decreased, near point of convergence was receded, and horizontal phoria showed a tendency of esodeviation. In the case of negative fusional vergence, with reduction of illumination intensity, the break point and the recovery point were decreased but in the case of positive fusional vergence, the break point was increased. The negative and positive relative accommodation were significantly decreased (p<0.05) with reduction of illumination intensity. Conclusions: In clinical practice, visual functional test should be performed under condition of adequate illumination level through patient's living environment and job.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.4
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• pp.381-388
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• 2012

Purpose: In this study, the changes in the shape of silicone hydrogel lenses, dryness of lens and objective/ subjective symptoms that could be induced by repeating dryness of lens and objective/subjective symptoms were investigated. Methods: After drying and rehydrating of silicone hydrogel lenses with different lens material and thickness for 4 times, their overall diameters and base curves were compared. Subjective symptoms, non-invasive tear break-up time (NIBUTs) and blinking rate were evaluated after wearing dehydrated silicone hydrogel lens. Results: Overall diameter and base curve increased in all tested silicone hydrogel lenses by repeating dryness and rehydration. The degree of change in over all diameter and base curve were variable on the material. There were irregular change of lens parameters in thicker lens. When the subjects wore silicone hydrogel lenses after drying and rehydrating, their NIBUTs were decreased and blink rates were increased regardless of lens material or thickness. In addition, repetitive drying of silicone hydrogel lenses affected the lens fitting. Therefore, subjective symptoms such as itching, pain, irritation, foreign body sensation, dryness tended to be increased. Conclusions: The results obtained from the study may suggest to develop durable silicone hydrogel contact lenses against dry environment since the changes in parameters of silicone hydrogel lens and the subjective discomfort were observed after repetitive drying and rehydration.