한국안광학회지 (Journal of Korean Ophthalmic Optics Society)

한국안광학회 (The Korean Ophthalmic Optics Society)
권호 표지
DOI QR코드

DOI QR Code

중심장액성맥락망막병증 눈의 시력 및 망막 상태 분석

Analysis of Visual Acuity and Retinal State in the Eyes with Central Serous Chorioretinopathy

  • 최종길 (서울과학기술대학교 안경광학과) ;
  • 이경민 (한길안과병원) ;
  • 김세일 (서울과학기술대학교 안경광학과) ;
  • 김소라 (서울과학기술대학교 안경광학과) ;
  • 박미정 (서울과학기술대학교 안경광학과)
  • Choi, Jong Kil (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Lee, Kyung Min (HanGil Eye Hospital) ;
  • Kim, Se-il (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Kim, So Ra (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Park, Mijung (Dept. of Optometry, Seoul National University of Science and Technology)
  • 투고 : 2016.05.06
  • 심사 : 2016.06.09
  • 발행 : 2016.06.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

목적: 중심장액성맥락망막병증을 가진 눈의 망막 두께 및 망막 부피와 같은 망막 상태와 시력과의 상관관계를 알아보았다. 방법: 총 78명 136안을 대상으로 중심장액성맥락망막병증을 치료 중인 눈 및 무증상 반대편 눈, 중심장액성맥락망막병증을 진단받은 후 완치된 눈 및 반대편 눈과 정상인 눈 각각의 나안시력, 최대교정시력, 망막 두께, 망막 부피를 측정하였다. 결과: 중심장액성맥락망막병증을 치료 중인 눈은 나안시력, 최대교정시력, 망막 두께, 망막 부피 모두에서 반대편 무증상 눈, 질환이 완치된 눈 및 정상 눈과 비교하여 통계적으로 유의하게 차이가 있었다. 중심장액성맥락망막병증의 반대편 무증상 눈의 최대교정시력은 정상 눈과 차이가 없었으나 망막 두께 및 망막 부피는 정상 눈과 통계적으로 유의한 차이가 있었다. 망막 두께가 증가함에 따라 망막 부피가 증가하는 정도가 정상안의 경우보다 중심장액성맥락망막병증 소견을 보이는 눈이나 반대편 무증상 눈, 중심장액성맥락망막병증이 완치된 눈 및 그 반대편 눈에서 더 컸다. 결론: 본 연구를 통하여 중심장액성맥락망막병증을 가지고 있는 눈 뿐만 아니라 반대편 무증상 눈에서도 망막 두께 및 망막 부피가 증가하며, 중심장액성맥락망막병증에 의한 최대교정시력의 변화는 일정 정도 이상의 망막 두께 및 망막 부피가 증가되었을 때 나타남을 밝혔다.

Purpose: The relationship between retinal conditions such as macular thickness and retinal volume of the eyes with central serous chorioretinopathy(CSC) and visual acuity was investigated. Methods: A total of 136 eyes from 78 subjects was divided into 5 groups: CSC eyes under treatment and its asymptomatic contralateral eyes, fully cured CSC eyes after the diagnosis and its contralateral, and normal eyes. Their uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), retinal thickness and retinal volume were further examined. Results: All of UCVA, BCVA, retinal thickness and retinal volume of CSC eyes under treatment were significantly different from those of asymptomatic contralateral eyes, fully cured CSC eyes and normal eyes. BCVA of the asymptomatic contralateral eyes was not significantly different from it of normal eyes, however, its retinal thickness and volume were significantly different from those of normal eyes. Increased degree of retinal volume along with the increase of retinal volume was greater in CSC eyes and its asymptomatic contralateral eyes, fully cured CSC eyes and its contralateral eyes than normal eyes. Conclusions: From the present study, it was revealed that the retinal thickness and volume of asymptomatic contralateral eyes of CSC increase as well as CSC eyes, and the change of BCVA due to CSC occurs only when the retinal thickness and volume increase in some extent.

키워드

참고문헌

  1. von Graefe A. Ueber centrale recidivirende retinitis. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1866;12:211-215.
  2. Donald J, Gass M. Pathogenesis of disciform detachment of the neuroepithelium: II. Idiopathic central serous choroidopathy. Am J Ophthalmol. 1967;63(3):587-615.
  3. Bennett G. Central serous retinopathy. Br J Ophthalmol. 1995;39(10):605-618.
  4. Konno S, Akiba J, Yoshida A. Retinal thickness measurements with optical coherence tomography and the scanning retinal thickness analyzer. Retina. 2001;21(1):57-61. https://doi.org/10.1097/00006982-200102000-00010
  5. Cohen AI. A possible cytological basis for the ‘R’ membrane in the vertebrate eye. Nature. 1965;205(4977):1222-1223. https://doi.org/10.1038/2051222a0
  6. Piccolino FC. Central serous chorioretinopathy: some considerations on the pathogenesis. Ophthalmologica. 1981; 182(4):204-210. https://doi.org/10.1159/000309115
  7. Bujarborua D. Longterm followup of idiopathic central serous chorioteinopathy without laser. Acta Ophthalmol Scand. 2001;79(4):417-421. https://doi.org/10.1034/j.1600-0420.2001.079004417.x
  8. Guyer DR, Yannuzzi LA, Slakter JS, Sorenson JA, Ho A, Orlock D. Digital indocyanine green videoangiography of central serous chorioretinopathy. Arch Ophthalmol. 1994; 112(8):1057-1062. https://doi.org/10.1001/archopht.1994.01090200063023
  9. Nunes S, Pereira I, Santos A, Bernardes R, Cunha-Vaz J. Central retinal thickness measured with HD-OCT shows a weak correlation with visual acuity in eyes with CSME. Br J Ophthalmol. 2010;94(9):1201-1204. https://doi.org/10.1136/bjo.2009.165662
  10. Spaide RF, Hall L, Haas A, Campeas L, Yannuzzi LA, Fischer YL et al. Indocyanine green videoangiography of older patients with central serous chorioretinopathy. Retina. 1996;16(3):203-213. https://doi.org/10.1097/00006982-199616030-00004
  11. Iida T, Kishi S, Hagimura N, Shimizu K. Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy. Retina. 1999;19(6):508-512. https://doi.org/10.1097/00006982-199911000-00005
  12. Giovannini A, Scassellati-Sforzolini B, D'Altobrando E. Choroidal findings in the course of idiopathic serous pigment epithelium detachment detected by indocyanine green videoangiography. Retina. 1997;17(4):286-293. https://doi.org/10.1097/00006982-199717040-00002
  13. Alam S, Zawadzki RJ, Choi S, Gerth C, Park SS, Morse L et al. Clinical application of rapid serial fourier-domain optical coherence tomography for macular imaging. Ophthalmology. 2006;113(8):1425-1431. https://doi.org/10.1016/j.ophtha.2006.03.020
  14. Ojima Y, Hangai M, Sasahara M, Gotoh N, Inoue R, Yasuno Y et al. Three-dimensional imaging of the foveal photoreceptor layer in central serous chorioretinopathy using high-speed optical coherence tomography. Ophthalmology. 2007;114(12):2197-2207. https://doi.org/10.1016/j.ophtha.2007.02.015
  15. Springer AD, Hendrickson AE. Development of the primate area of high acuity, 3: temporal relationships between pit formation, retinal elongation and cone packing. Vis Neurosci. 2005;22(2):171-185. https://doi.org/10.1017/S095252380522206X
  16. Provis JM, Diaz CM, Deher B. Ontogeny of the primate fovea: a central issue in retinal development. Prog Neurobiol. 1998;54(5):549-580. https://doi.org/10.1016/S0301-0082(97)00079-8
  17. Chen TC, Cense B, Pierce MC, Nassif N, Park BH, Yun SH et al. Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging. Arch Ophthalmol. 2005;123(12):1715-1720. https://doi.org/10.1001/archopht.123.12.1715
  18. Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29(10): 1469-1473. https://doi.org/10.1097/IAE.0b013e3181be0a83
  19. Menchini U, Virgili G, Lanzetta P, Ferrari E. Indocyanine green angiography in central serous chorioretinopathy. Int Ophthalmol. 1997;21(2):57-69. https://doi.org/10.1023/A:1005880129005
  20. Scheider A, Nasemann JE, Lund OE. Fluorescein and indocyanine green angiographies of central serous chori oretinopathy by scanning laser ophthalmoscopy. Am J Ophthalmol. 1993;115(1):50-56. https://doi.org/10.1016/S0002-9394(14)73524-X
  21. Bujarborua D, Chatterjee S, Choudhury A, Bori G, Sarma AK. Fluorescein angiographic features of asymptomatic eyes in central serous chorioretinopathy. Retina. 2005;25(4):422-429. https://doi.org/10.1097/00006982-200506000-00005
  22. Manjunath V, Taha M, Fujimoto JG, Duker JS. Choroidal thickness in normal eyes measured using Cirrus HD optical coherence tomography. Am J Ophthalmol. 2010;150(3): 325-329. https://doi.org/10.1016/j.ajo.2010.04.018
  23. Goebel W, Kretzchmar-Gross T. Retinal thickness in diabetic retinophy: a study using optical coherence tomography( OCT). Retina. 2002;22(6):759-767. https://doi.org/10.1097/00006982-200212000-00012
  24. Lee K, Sohn J, Choi JG, Chung SK. Optical quality in central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2014;55(12):8598-8603. https://doi.org/10.1167/iovs.14-14679
  25. Choi HW, Moon SW, Kim JS, Lee JH. Measurement and analysis of serous fluid in central serous chorioretinopathy using OCT. J Korean Ophthalmol Soc. 2008;49(2) 282-287. https://doi.org/10.3341/jkos.2008.49.2.282

피인용 문헌

  1. The Analysis of Optical Quality in Central Serous Chorioretinopathy by OQAS vol.21, pp.3, 2016, https://doi.org/10.14479/jkoos.2016.21.3.281