• 정신신체의학
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• 제11권1호
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• pp.25-35
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• 2003

연구목적: 파킨슨병 환자에서 다양한 정신증상이 동반되는 것으로 보고되고 있으며, 특히 우울증상의 동반율이 매우 높다고 보고되고 있다. 특히 파킨슨병은 완치가 어렵고, 치료의 초점이 질병의 진행 억제나 증상의 완화에 있기 때문에 파킨슨병 환자에서의 우울증상에 대한 관심과 치료는 중요하다. 본 연구는 통원치료 중인 파킨슨병 환자들을 대상으로 파킨슨병 관련 임상요인들과 우울증상 사이의 관련성을 조사하는데 목적이 있다. 연구대상 및 방법: 일 대학교병원 신경과 파킨슨병 클리닉에서 특발성 파킨슨병으로 진단 받고 치료중인 환자들 중 본 연구에 참여하기로 동의한 118명의 환자를 대상으로 하였다. 일반적인 인구통계학적 자료, 파킨슨병 관련 자료[발병연령, 치료약물 용량, 임상양상, Hoehn과 Yahr의 단계(Hoehn and Yahr stage, H&Y stage), 일상생활 평가척도(Modified Schwab and England Activities of Daily Living, ADL)], 파킨슨병 환자의 삶의 질 설문지(Parkinson's Disease quality of Life questionnaire, PDQL), 스필버그 상태/특성 불안척도, 간이정신 검사 등을 조사하였고, 우울증상의 평가는 Beck 우울척도(Beck Depression Inventory, BDI)를 이용하였다. 결 과: 대상군의 평균 연령은 $60.4\pm7.1$세(범위:34-73세)였고, 남성이 56명(47.5%), 여성이 62명(52.5%)이었다. 대상군은 BDI 점수에 따라 비우울군 39명(33.1%), 경도 우울군 15명(12.7%), 중등도 우울군 16명(13.6%), 중증 우울군 48명(40.7%)으로 분류되었다. 파킨슨병 환자의 우울증상은 H & Y stage(r=0.34, p<0.001) 및 파킨슨병 증상의 정도(r=0.35, p<0.001), 스필버그 특성 불안 척도(TAI)(r=0.33, p<0.001)와 양의 상관관계가 있었고, 교육정도(r=-0.34, p<0.001), ADL(r=-0.37, p<0.001), PDQL(r=-0.69, p<0.001)과 음의 상관관계를 보였다. 본 연구에서 사용한 검사도구 중 우울증을 예측하는데 가장 의미있는 척도는 PDQL(p<0.005)이었다. 결 론: Beck 우울척도를 이용한 평가에 의하면 본 연구 대상 환자 118명 중 79명(67%)이 주관적인 우울증상을 호소하고 있었다. 본 연구 결과는 파킨슨병 증상이 심할수록, 그리고 H & Y stage가 높을수록 우울증상이 심각함을 보여준다. 또한 BDI 점수가 높을수록 일상생활에서의 활동에 제한이 많으며, 삶의 질이 저하되어 있음을 시사한다. 따라서 본 연구결과는 파킨슨병 환자의 신체증상에 대한 치료 이외 우울증상에 대한 정신의학적 관심과 치료가 중요함을 뒷받침한다.

• 보건의료산업학회지
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• 제6권3호
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• pp.29-38
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• 2012

The aim of this study was to examine the spouse effects on depressive symptom and suicidal thinking among the elderly aged 65 and over in Korea. The subjects selected from the database of the Fourth Korea National Health and Nutrition Examination Survey(KNHANES IV) conducted by Korea Centers for Disease Control and Prevention from 2007 to 2009. Those who were female, older, lower educated, or poorer were more likely to live alone than their counterparts respectively. The elderly living alone experienced depressive symptom as 2.0 times(OR=2.004, 95% CI=1.433, 2.803) as, and suicidal thinking as 1.6 times(OR=1.567, 95% CI=1.111, 2.211) as the elderly couples did, adjusting for socio-economic factor, health status factors, and health behaviors factors. As for the male subgroup, the elderly living alone experienced depressive symptom as 4.0 times(OR=3.997, 95% CI=2.066, 7.732) as, and suicidal thinking as 3.2 times(OR=3.181, 95% CI=1.535, 6.592) as the elderly couples did. On the other hands, there was no significant difference in depressive symptoms and suicidal thinking between the female elderly living alone and couples. The authors suggested policy interventions to promote the mental health of the male elderly living alone.

• Journal of Korean Biological Nursing Science
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• 제21권2호
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• pp.123-132
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• 2019

Purpose: The purpose of this study was to identify influencing factors of metabolic index and cardiovascular risk factors, on depressive and non-depressive groups, in vulnerable diabetic elderly women. Methods: Participants were 137 vulnerable diabetic elderly women, using health centers in D city. Data were collected through interviews September though December 2017. The metabolic index was measured using National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), and cardiovascular risk factors were measured using Framingham Risk Score (FRS). Depressive and non-depressive groups were divided by the score of Geriartric Depress Scale Short Korea Version (GDSSF). Collected data were analyzed using a x2 test, independent t-test, and binary logistic regression, with the SPSS/WIN 25.0 program. Results: Vulnerable diabetic elderly women, did not exercise in the depressive groups, and had higher triglyceride (TG), total cholesterol (TC) and larger waists, than in the non-depressive group. Results show that lack of exercise (OR= 6.30), is the highest risk factor, influencing the depressive symptom in vulnerable diabetic elderly women. Conclusion: These results suggest that to reduce depressive symptom levels among vulnerable diabetic elderly women, nursing interventions are needed to increase exercise and decrease TG, TC, and waist size, particularly in improving exercise of vulnerable diabetic elderly women.

• 한국노년학
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• 제29권4호
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• pp.1611-1628
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• 2009

건강상태와 심리사회적 요인이 우울증상과 밀접한 관련이 있다는 것은 기존연구를 통하여 널리 알려진 사실이다. 하지만 기존의 종단데이터 부족과 분석방법의 한계로 이러한 변수들과 우울증상 궤적과의 관계에 대해서는 알려진 바가 많지 않다. 이러한 기존 연구의 한계를 염두에 두고, 본 연구는 건강상태 및 심리사회적 요인과 우울증상의 궤적간의 관계를 살펴보는 것을 주 목적으로 한다. 본 연구는 전국 대표샘플인 한국복지패널데이터 1, 2, 3차 자료를 이용하여 60세 이상의 노인들(N=4,919)의 우울궤적 예측요인을 잠재성장모형을 이용하여 분석하였다. 사회경제적 변수를 통제한 상태에서 건강변수와 심리사회적 변수들이 우울궤적에 미치는 영향은 기존연구와 유사한 점도 있지만 다른 점도 있는 것으로 나타났다. 구체적으로 건강변수는 우울증상의 수준에는 영향을 미치지만 우울증상의 변화속도에는 영향을 미치지 않는 것으로 나타났다. 반면 심리사회적 변수는 기존 연구와 동일하게 모두 우울수준에 영향을 미치지만, 기존 연구와는 다르게 변수에 따라서 우울증상의 변화속도에 미치는 영향은 상이한 것으로 나타났다. 즉, 자아존중감과 가족관계 변수는 우울증상 변화속도에 긍정적 영향을 미치는 반면, 사회적 관계는 우울증상 변화속도에 부정적 영향을 미치는 것으로 나타났다. 이러한 연구결과를 토대로 실천 및 향후 연구를 위한 함의를 논의하였다.

• 동의신경정신과학회지
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• 제14권2호
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• pp.199-206
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• 2003

Objective : This is a case report of the patient diagnosed as the depressive episode mixed with organic depressive disorder. Method : We treat the patient with herbal medication and gave acupuncture treatment about 5 weeks, the symptom of the patient improved. The herbal medication and acupuncture treatment which we gave patient was based on Oriental medical diagnosis. Results : The patient had been taken the western medical treatment for 2 months, the symptom of the patient was not improved. But after the Oriental medical treatment, the patient is on the improving state. Conclusion : In the treatment of the depressive disorder which is mixed with organic depressive disorder, we found that the Herbal medication and Acupuncture based on correct 'Byonjung(辦證)' help the care of depressive episode which is mixed with organic depressive disorder.

• 생물정신의학
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• 제24권3호
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• pp.149-154
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• 2017

Objectives This study investigated associations between symptom severity and neurocognitive functions in patients with major depressive disorder using comprehensive neuropsychological tests. Methods Ten patients with low depression (LD) and 22 patients with high depression (HD) participated. Symptom severity was determined by both the Beck Depression Inventory and the Hamilton Depression Rating Scale. Additionally, anxiety was measured by the Korean version of the State-Trait Anxiety Inventory (STAI-KYZ). Ten subtests of the Korean-Wechsler Adult Intelligence scale (K-WAIS), Stroop test, the word/design fluency tests were administered to assess cognition. Results The LD and HD groups did not differ in any of cognitive measures but anxiety level. Namely, the HD group obtained significantly higher scores on the state (U = 29.50, p < 0.01) and trait (U = 28.50, p < 0.001) anxiety scales than the LD group. A significant interaction effect between trait anxiety and depression severity was observed on the picture arrangement subtest of the K-WAIS [F (1, 27) = 5.09, p < 0.05]. Conclusions Cognitive deficits observed in patients with major depressive disorder may be related to other factors rather than current symptom severity. Trait anxiety possibly moderates the effect of current symptom severity on social judgment in these patients.

• 보건의료산업학회지
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• 제9권2호
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• pp.69-79
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• 2015

This study examined the relationship between family support and symptom of depressive among married working women, using the dataset of the Korean Longitudinal Survey of Women & Family (KLoWF 4th). There were 1,875 subjects. A multiple regression model was used to study the association between family support and symptom of depressive, controlling for economic-socio characteristics, health status and health behavior. Additionally, this study ran three subgroup regression models based on hierarchical model. From the results, there was a negative relationship between marriage happiness (b=-0.369, p<0.001), spouse satisfaction (b=-0.143, p=0.010), frequency of meeting with the wife's family (once a month: b=-0.952, p=0.012) and symptom of depressive (model 3). This negative relationship was also seen in the two subgroup regression models (models 1, and 2). The results of this study show the importance of family support for promoting mental health among married working women.

• 정신신체의학
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• 제3권2호
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• pp.126-138
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• 1995

For investigating a disease specific psychological mechanism in various dermatological disorders, we tried to explore the difference in correlation among stress perception, locus of control as a coping strategy, depressive symptoms and pruritic symptoms in the patients with psychological pruritis and chronic urticaria. The subjects were composed of 32 patients with psychol-ogical pruritis and 67 patients with chronic urticaria(subject group), and 25 patients with organic pruritis and 59 patient with major depression(control group). Global assesment of recent stress scale(GARS), I-E locus of control scale, Beck Depression Inventory(BDI) and medical college of wisconsin center pain follow up questionnaire were used for assesement. The results were as follows: 1) There were a significant positive correlation between stress perception and depressive symptom in patients with psychological pruritis, chronic urticaria, and major depression but not hi organic pruritis. 2) In relationship between locus of control and depressive symptom, patients with psychological pruritis, organic pruritis, and major depression except chronic ruticaria showed a significant negative correlation. 3) For intensity and pattern of pruritis, there were positive relations with depressive symptom and stress perception only in patients with chronic urticaria. Above results indicate that stress perception and locus of contorl may play a significant role in the formation of psychological and dermatological symptoms in psychological pruitis and chronic urticaria. But the mechanisms of these processes are different in either disorder.

• 한국학교보건학회지
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• 제24권1호
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• pp.71-80
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• 2011

Purpose: This study was conducted to compare the level of depressive symptom, spiritual well-being and faith maturity between college freshmen and seniors and to investigate the affecting factors on their depressive symptom. Methods: The study was cross-sectional descriptive survey. A self-report questionnaire were used to collect data from 335 college students during June to July, 2010. Data were analyzed by ${\chi}^2$-test, t-test, ANOVA, Scheffe's test, pearson correlation coefficient, and stepwise multiple regression using the SPSS/WIN 14.0 program. Results: The mean score of depressive symptom was $17.55{\pm}11.24$ and prevalence of depression was 26.5% in college freshmen. And those in college seniors were $14.18{\pm}14.17$ and 17.4%. And those were significantly higher in college freshmen than in seniors. The depressive symptom was a significant negative correlation with spiritual well-being, existential spiritual well-being, religious spiritual well-being, and faith maturity. Factors significantly influencing on depression in college freshmen included existential spiritual well-being, subjective health status, age, and confidence of salvation ($R^2$=49.7%). And those in college seniors included existential spiritual well-being and life satisfaction ($R^2$=53.3%). Conclusion: The counseling program and spirituality development program for preventing depression considering these affecting factors for especially college freshmen are necessary.

• 대한불안의학회지
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• 제7권1호
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• pp.9-15
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• 2011

Objectives : We examined the reliability and validity of the Korean version of the Depression and Somatic Symptom Scale (DSSS) in Korean patients with depressive symptoms. Methods : Participants were 55 outpatients diagnosed with major depressive disorder, a depressive episode of bipolar I disorder, somatoform disorder, panic disorder, generalized anxiety disorder, or post-traumatic stress disorder according to the DSM-IV criteria. We assessed them using the Korean versions of the DSSS, Hamilton Depression Rating Scale (HDRS), and Quick Inventory of Depressive Symptomatology Self Report (QIDS-SR). Results : The Korean version DSSS had a Cronbach's alpha of 0.90. Moreover, each item's correlation with the total score was statistically significant (r=0.24-0.71, p<0.01). The test-retest correlation coefficient (r=0.83, p<0.01) was relatively high, and the DSSS correlations with the HDRS and QIDS-SR were 0.77 and 0.74, respectively. Conclusion : These results demonstrate that the Korean version of the DSSS could be a reliable and valid tool for screening and assessing depressive patients. The Korean version of the DSSS will be a useful tool for screening both depressive and somatic symptoms in Korea.