• 제목/요약/키워드: Deoxyribonucleic acid

검색결과 81건 처리시간 0.019초

바이오인포매틱스(Bioinformatics) 서비스의 적정가격 산정에 관한 연구 (A Study on deciding optimal price of Bioinformatics services)

  • 최원훈;강경식
    • 대한안전경영과학회지
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    • 제18권1호
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    • pp.203-208
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    • 2016
  • Bioinformatics service is very new and emerging in market that provides information such as whether or not occurrence of a particular disease through the base of DNA(Deoxyribonucleic Acid) & RNA(Ribo Nucleic Acid) sequence analysis. Recently, interest growing rapidly in utilization of the industrial purpose, but provision of commercialization like pricing and service packaging is not enough to go to market. For go-to-market, firstly refine the services and perform cost calculation of services in cost-plus method then estimate consumer utility by conducting conjoint analysis. Collectively, with cost and consumer utility result, optimal service price can be calculated.

DEGRADATION OF NUCLEIC ACIDS BY CELL-FREE EXTRACT OF MIXED RUMEN PROTOZOA OF BUFFALO RUMEN

  • Sinha, P.R.;Dutta, S.M..
    • Asian-Australasian Journal of Animal Sciences
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    • 제1권4호
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    • pp.219-222
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    • 1988
  • Degradation of deoxyribonucleic acid(DNA) and ribonucleic acid(RNA) by cell-free extract of mixed rumen protozoa of buffalo rumen was investigated. DNA was observed to be degraded rapidly during an initial incubation period of 2 hr with simultaneous appearance of degradation products. RNA on the other hand recorded a rapid degradation during an initial incubation period of 1 hr. RNA degradation products appeared upto an incubation period of 2 hr. DNA was observed to degrade into oligo- and mononucleotides. pyrimidine nucleosides, purine nucleoside adenosine and bases xanthine, hypoxanthine and thymine. Degradation products of RNA comprised of pyrimidine nucleosides, purine nucleoside, adenosine and bases xanthine, hypoxanthine and uracil besides oligo- and mononucleotides.

염색체 말단부위 (Back to the Ends: Chromosomal DNA)

  • 이미형;서동철
    • Childhood Kidney Diseases
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    • 제12권1호
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    • pp.1-10
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    • 2008
  • Nucleic scids transfer the genetic information for serving a central biological purpose. The nucleic acids are polymers of nucleotides and they are mainly ribonucleic acid(RNA) and deoxyribonucleic acid(DNA). The nucleotides are stoichiometrically composed of five-carbon sugars, nitrogeneous bases, and phosphoric acids. The chemistry of nucleic acids and characteristics of different genomes are decribed for further study. Most of DNA genomes tend to be circular including bacterial genomes and eukaryotic mitochondrial DNA. Eukaryotic chromosomes in cells, in contrast, are generally linear. The ends of linear chromosomes are called telomeres. The genomes of different species, such as mammals, plants, invertebrates can be compared with the chromosome ends. The telomeric complex allows cells to distinguish the random DNA breaks and natural chromosomal ends. The very ends of chromosomes cannot be replicated by any ordinary mechanisms. The shortening of telomeric DNA templates in semiconservative replication is occurred with each cell division. The short telomere length is critically related to aging, tumors and dieases.

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대두의 핵산, 단백질 및 물질생산에 미치는 인산비료의 효과 (DNA, RNA, Protein and Yield of the Soybean Plant, Glycine max Merr., as Affected by Phosphorus Nutrition)

  • 장남기
    • Journal of Plant Biology
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    • 제16권1_2호
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    • pp.23-29
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    • 1973
  • The effect of phosphorus nutrition on the content of deoxyribonucleic acid(DNA), ribonucleic acid(RNA), crude protein and plant growth of soybean plant(Glycine max, Merr.) was studied. Yields of the above-and under-ground parts of the soybean plant in terms of dry weight, the amounts of crude protein, RNA and DNA continued to increase with increasing phosphorus supply. The amounts of RNA and crude protein were highest in the leaf tissues where most intensive growth was taking place. The relationships among DNA, RNA, crude protein and plant growth appeared to consist of the central dogma which has immortalized, while DNA in plant tissue was subject to charges cuased by external environmental facters such as phosphorus nutrition.

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The Origin of Artificial Species: Genetic Robot

  • Kim Jong-Hwan;Lee Kang-Hee;Kim Yong-Duk
    • International Journal of Control, Automation, and Systems
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    • 제3권4호
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    • pp.564-570
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    • 2005
  • This paper provides a basis for investigating 'The Origin of Artificial Species,' as a robot can be considered as an artificial creature. To design an artificial creature, its general internal architecture is presented and its artificial chromosomes are proposed as its essential components. Rity as an artificial creature is developed in a virtual world of PC to test the world's first robotic 'chromosomes,' which are a set of computerized DNA (Deoxyribonucleic acid) codes for creating robots (artificial creatures) that can have their own personality, and can ultimately reproduce their kind, or even evolve as a distinct species. The effectiveness of the artificial chromosomes is demonstrated by implanting the genetic code into two Ritys living in a virtual world, in order to define their personality.

생물학적 DNA 구조와 트러스구조의 융합으로 개발한 바람개비형 모델 선행연구 (Preliminary Development of Pinwheel Model Created by Convergent Truss Structure with Biological DNA Structure)

  • 최정호
    • 한국융합학회논문지
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    • 제7권4호
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    • pp.181-190
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    • 2016
  • The objective of this study is to find the effective stiffness and compressive strengths of a unit-cell pinwheel truss and double pinwheel truss model designed following a double helical geometry similar to that of the DNA (deoxyribonucleic acid) structure in biology. The ideal solution for their derived relative density is correlated with a ratio of the truss thickness and length. To validate the relative stiffness or relative strength, ABAQUS software is used for the computational model analysis on five models having a different size of truss diameter from 1mm to 5mm. Applied material properties are stainless steel type 304. The boundary conditions applied were fixed bottom and 5 mm downward displacement. It was assumed that the width, length, and height are all equal. Consequently, it is found that the truss model has a lower effective stiffness and a lower effective yielding strength.

Methylobacterium sp. GL-10이 생산하는 3-Hydroxybutyrate와 3-Hydroxyvalerate의 Copolyester (Copolyester of 3-Hydroxybutyrate and 3-Hydroxyvalerate Produced by Methylobacterium sp. GL-10)

  • 이호재;박진서;이용현
    • 한국미생물·생명공학회지
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    • 제19권1호
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    • pp.94-99
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    • 1991
  • - The further study for the identification of the previously reported pink-pigmented facultative methylotrophic bacterium (PPFM) GL-10 was carried out. The PPFM GL-10 was Gram nagative, rod, and motile by a single polarly inserted flagellum. The colonies were smooth, pink, circular, along with convex with entire margin. The isolate could utilize C1 compounds and a variety of multicarbon substrates as sole carbon and energy source. The isolate was obligately aerobic, and exhibited both catalase and oxidase activities. The deoxyribonucleic acid base composition was 65-67 mol% guanine plus cytosine. The isolate was mostly identical with Methylobacterium extorquens and named Methylobacterium sp. strain GL-10. Methylobacterium GL-10 accumulated a copolyester of 3-hydroxybutyrate and 3-hydroxyvalerate (poly-3HB/3 HV) when grown in nitrogen-free culture media containing sodium propionate as substrate at the second polyester accumulation stage. The composition of copolyester, as determined from $^1h$ NMR spectra, was 23 mol% of 3-hydroxyvalerate (3HV).

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치아에서의 DNA 유전자지문 분석 -Chelex$^\textregistered$ 100을 매개체로 한 DNA추출- (Analysis of the DNA Fingerprints from the Teeth -Using Chelex$^\textregistered$ 100 as a Medium of Simple Extraction of DNA from the Teeth-)

  • Chang-Lyuk Yoon
    • Journal of Oral Medicine and Pain
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    • 제20권2호
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    • pp.515-528
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    • 1995
  • The human genomic deoxyribonucleic acid(DNA) was extracted from the pulp, dentin of 22 teeth by clelex, phenol methods. Samples of the tooth-derived DNA were amplified by polymerase chain reaction(PCR), electrophosed for sex determination by detection of X-Y homologus amelogenin gene and D1S80 locus detection The following results have been achieved. 1. Chelex and phenol method are effective to sex determination in the pulp and dentin 2. Chelex method is not suitable for detection of D1S80 locus. 3. Concentration and purity of DNA for teeth using chelex method is lower than using phenol method. From the above investigation, chelex method is simple, rapid for sex determination, but it is not suitable for detection of VNTRs.

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Electrochemical and Spectroscopic Studies on the Interaction between DNA and the Product of Enzyme-catalyzed Reaction of OPD-H2O2-HRP

  • Niu, S.Y.;Zhang, S.S.;Ma, L.B.;Jiao, K.
    • Bulletin of the Korean Chemical Society
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    • 제25권6호
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    • pp.829-832
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    • 2004
  • The pure product of 2,3-diaminophenazine was prepared by the enzyme-catalyzed reaction of ophenylenediamine-$H_2O_2$-horseradish peroxidase and characterized by UV/Vis spectroscopy, IR spectroscopy and NMR spectroscopy. The electrochemical behaviour of 2,3-diaminophenazine on the glassy carbon electrode was studied. The interaction between 2,3-diaminophenazine and deoxyribonucleic acid was studied by cyclic voltammetry method and UV/Vis spectroscopy, which indicated that the interaction between them is intercalation. The influence of reacting time was also studied. The binding ratio of the 2,3-diaminophenazine-DNA complex is calculated to be 1 : 2 and the binding constant is to be $5.07{\times} 10^3L{\cdot}mol^{-1}$ at room temperature.