• Journal of dental hygiene science
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• v.15 no.6
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• pp.807-814
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• 2015

The purpose of this study is to create a hypothetical model that explains and predicts oral health promotion behavior of adolescents by reviewing preceding literature on Pender's Health Promotion Model, and to verify the model's validity and proposed hypothesis through PLS (partial least square) structural equation model analysis. This study was cross-sectional survey consisted of self-administration questionnaires. The subjects in this study were a total of 293 alternative high school students in Jeollabuk-do Province. They were selected by convenience sampling. In alternative high school students, perceived benefit, locus of control, self-efficacy, and self-esteem had an effect on their oral health promoting behavior. As a result of the indirect effects in black is subjectively good subjective oral health, oral health related behaviors well past the more oral health promotion behavior showed a high. The prediction model of oral health promotion for adolescences, which was made using Pender's Health Promotion Model, was considered to be useful in explaining and predicting alternative high school students oral health promotion behavior.

• KSBB Journal
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• v.31 no.1
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• pp.52-57
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• 2016

Mutant p53 (R280K) is highly expressed in MDA-MB-231 triple-negative human breast cancer cells. Currently, we reported the role of mutant p53-R280K in mediating the survival of MDA-MB-231 cells in vitro. The present study was undertaken to determine whether mutant p53-R280K affects breast cancer cell growth in vivo. To this end, we used small interfering RNA to knockdown the level of mutant p53-R280K in MDA-MB-231 cells. Silencing of mutant p53-R280K in MDA-MB-231 cells causes substantial tumor regression of established xenografts in vivo. In xenograft model for breast cancer, silencing of mutant p53-R280K in MDA-MB-231 cells significantly inhibited the tumor growth. Moreover, TUNEL assay showed more occurrence of apoptotic cells in mutant p53-R280K silenced tumors compared to control. Our data indicate that mutant p53-R280K has an important role in mediating tumor growth of MDA-MB-231 cells in vivo. Taken together, this study suggests that endogenous mutant p53-R280K could be used as a therapeutic target for breast cancer cells harboring this TP53 missense mutation.

• Journal of Technologic Dentistry
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• v.42 no.1
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• pp.9-16
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• 2020

Purpose: The purpose of this study was to compare the marginal and internal fit of lithium disilicate ceramic inlay produced by heat pressing that inlay pattern made by subtractive manufacturing and additive manufacturing method. Methods: A mandibular lower first molar that mesial occlusal cavity (MO cavity) die was prepared. After fabricating an epoxy resin model using a silicone impression material, epoxy resin die was scanned with a dental model scanner to design an MO cavity inlay. The designed STL pile was used to fabricate wax patterns and resin patterns, and then lithium disilicate ceramic inlays were fabricated using hot-press method. For the measurement of the marginal and internal gap of the lithium disilicate, silicone replica method was applied, and gap was measured through an optical microscope (x 80). Data were tested for significant differences using the Mann-Whitney Utest. Results: The marginal fit was 103.56±9.92㎛ in the MIL-IN group and 81.57±9.33㎛ in the SLA-IN group, with a significant difference found between the two groups (p<0.05). The internal fit was 120.99±17.52㎛ in the MIL-IN group and 99.18±6.65㎛ in the SLA-IN group, with a significant difference found between the two groups (p<0.05). Conclusion: It is clinically more appropriate to apply the additive manufacturing than subtractive manufacturing method in producing lithium disilicate inlay using CAD/CAM system.

• Journal of Korean society of Dental Hygiene
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• v.23 no.4
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• pp.277-286
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• 2023

Objectives: In this study, we aimed to develop a systematic tool that can evaluate the effects of interprofessional education (IPE) by applying four core competencies (values/ethics for interprofessional practice, roles/responsibilities, interprofessional communication, and teams and teamwork) and an educational evaluation model to evaluate the learning, behavior of learners, and results step by step. Methods: Previous studies on IPE evaluation tools were analyzed, and an evaluation tool (draft) was developed by modifying questions suitable for evaluation according to the Kirkpatrick model's stages and core competencies. The evaluation tool was completed by conducting a Delphi survey twice with 4-6 experts. To analyze the Delphi survey, the content validity index (CVI) was calculated, and the reliability coefficient (Cronbach's alpha coefficient) was used to measure reliability. Results: 29 questions on pre-education, consisting of learning and behavior stages, and 54 questions on post-education, consisting of reaction, learning, behavior, and results stages, were developed. The CVI and Cronbach's alpha coefficient values were >0.8 and >0.6, respectively. Conclusions: The IPE evaluation tool developed in this study is expected to contribute to the evaluation of the educational level of IPE and the identification of points for improvement when applied to various educational settings.

• Imaging Science in Dentistry
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• v.54 no.1
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• pp.33-41
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• 2024

Purpose: The aims of this study were to create a deep learning model to distinguish between nasopalatine duct cysts (NDCs), radicular cysts, and no-lesions (normal) in the midline region of the anterior maxilla on panoramic radiographs and to compare its performance with that of dental residents. Materials and Methods: One hundred patients with a confirmed diagnosis of NDC (53 men, 47 women; average age, 44.6±16.5 years), 100 with radicular cysts (49 men, 51 women; average age, 47.5±16.4 years), and 100 with normal groups (56 men, 44 women; average age, 34.4±14.6 years) were enrolled in this study. Cases were randomly assigned to the training datasets (80%) and the test dataset (20%). Then, 20% of the training data were randomly assigned as validation data. A learning model was created using a customized DetectNet built in Digits version 5.0 (NVIDIA, Santa Clara, USA). The performance of the deep learning system was assessed and compared with that of two dental residents. Results: The performance of the deep learning system was superior to that of the dental residents except for the recall of radicular cysts. The areas under the curve (AUCs) for NDCs and radicular cysts in the deep learning system were significantly higher than those of the dental residents. The results for the dental residents revealed a significant difference in AUC between NDCs and normal groups. Conclusion: This study showed superior performance in detecting NDCs and radicular cysts and in distinguishing between these lesions and normal groups.

• Journal of Korean society of Dental Hygiene
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• v.18 no.1
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• pp.77-92
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• 2018

Objectives: The purpose of this study was to review depression and anxiety associated with pain during scaling procedures, and to establish measures for reducing scaling pain encompassing not only physical factors but also psychological aspects of patients. This study also attempts to reduce anxiety through proper patient education prior to scaling procedures. Methods: In Seoul, and Gyeonggi area from July 26, 2017 to August 19, 2017, there were 327 copies of questionnaire data collected, excluding 23 questionnaires with insufficient information such as missing entries. The following inductions were made based on data collected. Results: There are positive correlations between pain and depression, dental anxiety, trait anxiety, and state anxiety. Especially, stronger correlation is present between pain and dental anxiety. Depression (${\beta}=0.439$, p<0.001) is the most influential factor associated with pain. Next is dental anxiety (${\beta}=0.292$, p<0.001). Higher the depression and dental anxiety tend to increase pain over scaling procedure. This model is with adjusted explanatory power of 28.2%. Conclusions: The result demonstrates that there is a correlation between scaling pain and depression, dental anxiety, trait anxiety, and state anxiety. Especially, depression and dental anxiety were prominent factors in affecting scaling pain. Therefore, considering aforementioned-findings, a dental hygienist's positive attitude may help in reducing the pain of the patient during scaling procedures, by affecting the psychological state of the patient and reduce the anxiety through proper education prior to scaling procedures.

• Journal of The Korean Society of Integrative Medicine
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• v.6 no.3
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• pp.93-102
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• 2018

Purpose : The purpose of this study was to conduct an in-depth interview with dentists in order to provide fundamental data regarding their thoughts in relation to the dental hygiene process of care and its necessity in clinical practice, with the aim of ensuring that dental hygienists can perform their duties as experts. Method : Following explanation of the study, we administered the questionnaire to those who agreed to participate between September 26 and October 28, 2017. A Naver-form (mobile) questionnaire was distributed to the research subjects for data collection. Data were analyzed using SPSS (Statistical Package for the Social Sciences) 24.0. Analysis was performed by calculating the frequency and percentage of the general characteristics of the subjects, occupational expertise, and the dental hygiene process of care. Result : Among the 56 research subjects, 48 (85.7 %) were men and 8 (14.3 %) were women. Awareness on the part of respondents of the job responsibilities associated with the dental hygiene process of care ratio was as follows: 11 (19.6 %) categorized their level of knowledge regarding the dental hygienist's job duties as "very much know"; 13 (23.2 %) as "somewhat know"; 18 (32.1 %) as "neither"; and 9 (16.1 %) as "somewhat don't know", while 5 (9.0 %) said "I have no idea". The dental hygiene process of care was categorized as "very much necessary" by 50.0 % of respondents; as "somewhat necessary" by 35.7 %; and as "neither" by 14.3 %. Conclusion : The dental hygiene process of care is one of the methods used to continuously manage patients with dental-related concerns. Recently, the management of patients in the dental clinic has changed from a disease treatment model to a concept of active prevention for improving the quality of life related to oral health. The dental hygiene process of care is considered a very necessary dental health care service because it functions to continuously introduce oral health care or preventive care programs in clinical practice.

• Journal of Korean society of Dental Hygiene
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• v.18 no.2
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• pp.165-175
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• 2018

Objectives: This study aims to examine the factors that influence the organizational citizenship behavior of clinical dental hygienists to use them as basic data for improving effectiveness and efficiency of dental clinics and hospitals. Methods: A self-reported questionnaire was answered by 250 clinical dental hygienists in Seoul, Gyeonggi, Chungcheong, Jeolla and Gyeongsang province areas who were chosen using convenient sampling method from May 1st to June 30th of 2017. The data was analyzed using IBM SPSS/WIN 22.0 factor analysis on clinical dental hygienists' organization citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction. T-test and one-way ANOVA were performed for subjects' general characteristics and organizational citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction depending on their job characteristics. The mean comparison was drawn using the Scheffe test. Pearson's correlation and multiple regression analysis were performed to examine the relation of clinical dental hygienists' organizational citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction Also, the significance level was set at 0.05. Results: Clinical dental hygienists' organizational citizenship behavior was 3.84 points with organizational commitment of 3.27, empowerment of 3.41, self-leadership 3.45 and job satisfaction of 3.57. Factors that influence clinical dental hygienists' organizational citizenship behavior appeared in the order of organizational commitment, job satisfaction, self-leadership, empowerment and job intensity, and the model's explanation power was 45.6%. Conclusions: Clinical dental hygienists' organizational citizenship behavior was correlated to career, organizational commitment, empowerment, self-leadership and job satisfaction, where organizational commitment had the biggest influence. Therefore, clinical dental hygienists organizational citizenship behavior needs further studies and investigtae more ways to promote factors that influence organizational citizenship behavior.

• The Journal of Advanced Prosthodontics
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• v.10 no.5
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• pp.367-373
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• 2018

PURPOSE. To evaluate the fit of a crown produced based on a 3D printed model and to investigate its clinical applicability. MATERIALS AND METHODS. A master die was fabricated with epoxy. Stone dies were fabricated from conventional impressions (Conventional stone die group: CS, n=10). Digital virtual dies were fabricated by making digital impressions (Digital Virtual die group: VD, n=10). 3D data obtained from the digital impression was used to fabricate 3D printed models (DLP die group: DD, n=10, PolyJet die group: PD, n=10). A total of 40 crowns were fabricated with a milling machine, based on CS, VD, DD and PD. The inner surface of all crowns was superimposed with the master die files by the "Best-fit alignment" method using the analysis software. One-way and 2-way ANOVA were performed to identify significant differences among the groups and areas and their interactive effects (${\alpha}=.05$). Tukey's HSD was used for post-hoc analysis. RESULTS. One-way ANOVA results revealed a significantly higher RMS value in the 3D printed models (DD and PD) than in the CS and DV. The RMS values of PD were the largest among the four groups. Statistically significant differences among groups (P<.001) and between areas (P<.001) were further revealed by 2-way ANOVA. CONCLUSION. Although the fit of crowns fabricated based on the 3D printed models (DD and PD) was inferior to that of crowns prepared with CS and DV, the values of all four groups were within the clinically acceptable range (<$120{\mu}m$).

• International Journal of Oral Biology
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• v.31 no.2
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• pp.33-43
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• 2006

Dysplasia-associated seizure disorders are markedly resistant to pharmacological intervention. Relatively little research has been conducted studying the effects of antiepileptic drugs(AEDs)on seizure activity in a rat model of dysplasia. We have used rats exposed to methylazoxymethanol acetate(MAM) in utero, an animal model featuring nodular heterotopia, to investigate the effects of AEDs in the dysplastic brain. Pilocarpine was used to induce acute seizure in MAM-exposed and age-matched vehicle-injected control animals. Field potential recordings were used to monitor amplitude and numbers of population spikes, and paired pulse inhibition in response to stimulation of commissural pathway. Two commonly used AEDs were tested: diazepam 5, 2.5 mg/kg; phenytoin 40, 60 mg/kg. Diazepam(DZP) and phenytoin(PHT) reduced the amplitude of population spike in control and MAM-exposed rats. However, the amplitude of population spike was nearly eliminated in control rats as compared to the MAM-exposed rats. Pharmaco-resistance was tested by measuring seizure latencies in awake rats after pilocarpine administration(320 mg/kg, i.p.) with and without pretreatment with AEDs. Pre-treatment with PHT 60 mg prolonged seizure latency in control rats, but not in MAM-exposed animals. The main findings of this study are that acute seizures initiated in MAM-exposed rats are relatively resistant to standard AEDs assessed in vivo. These data suggest that animal model with cortical dysplasia can be used to screen the effects of potential AEDs.