• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.10
• /
• pp.4135-4141
• /
• 2014

Background: Human papillomaviruses (HPV) may play an important role as one of the possible etiologies of oral squamous cell carcinoma (OSCC). The present study aimed to investigate the association between HPV and OSCC in young Japanese patients by examining the presence of HPV DNA and surrogate markers in OSCC tissues. Materials and Methods: Forty young patients with OSCC whose surgical specimens were available were analyzed and compared with 40 patients randomly recruited from a pool of patients aged >40 years. HPV DNA was detected using the polymerase chain reaction-based AMPLICOR$^{(R)}$ HPV test, and surrogate markers of HPV infection were analyzed using immunohistochemical techniques to detect $p16^{INK4a}$ and p53. Results: Only two (5%) young patients and one (2.5%) older patient were positive for HPV DNA. $p16^{INK4a}$ overexpression was identified in six (15%) young patients. p53 staining levels were not high in tissues of most young patients (27 patients, 67.5%). HPV DNA status did not significantly correlate with $p16^{INK4a}$ expression levels. Profiles of increased levels of $p16^{INK4a}$ expression with diminished levels of p53 staining were not associated with the presence of HPV DNA. The combined p53 with $p16^{INK4a}$ profiles were significantly correlated with alcohol consumption in younger patients (p=0.006). Conclusions: Results of the present study indicate that HPV is less likely to cause OSCC in young Japanese patients, and the $p16^{INK4a}$ expression level is not an appropriate surrogate marker for HPV infection in OSCC.

• Journal of Periodontal and Implant Science
• /
• v.51 no.4
• /
• pp.226-238
• /
• 2021

Purpose: Although several reports have described the relationship between periodontal disease and cardiovascular disease, information about the association between periodontal disease and the progression of degenerative aortic stenosis (AS) is lacking. Therefore, we performed a retrospective, single-center, pilot study to provide insight into this potential association. Methods: Data from 45 consecutive patients (19 men; median age, 83 years) with mild or moderate degenerative aortic stenosis were analyzed for a mean observation period of 3.3±1.9 years. The total amount of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and titers of serum immunoglobulin G (IgG) against periodontal bacteria and high-sensitivity C-reactive protein (hs-CRP) were evaluated. Aortic valve area (AVA), maximal velocity (Vmax), mean pressure gradient (mean PG), and the Doppler velocity index (DVI) were evaluated. The change in each parameter per year ([Parameter_LATEST-Parameter_BASELINE]/Follow-up Years) was calculated from the retrospective follow-up echocardiographic data (baseline vs. the most recently collected data [latest]). Results: No correlation was found between the concentration of periodontopathic bacteria in the saliva and AS status/progression. The anti-P. gingivalis antibody titer in the serum showed a significant positive correlation with AVA and DVI. Additionally, there was a negative correlation between the anti-P. gingivalis IgG antibody titer and mean PG. The hs-CRP concentration showed positive correlations with Vmax and mean PG. Meanwhile, a negative correlation was observed between the anti-P. gingivalis IgG antibody titer and ΔAVA/year and Δmean PG/year. The hs-CRP concentration showed positive correlations with Vmax and mean PG, and it was significantly higher in patients with rapid aortic stenosis progression (ΔAVA/year <-0.1) than in their counterparts. Conclusions: Our results suggest that periodontopathic bacteria such as A. actinomycetemcomitans and P. gingivalis are not directly related to the status/progression of degenerative AS. However, inflammation and a lower immune response may be associated with disease progression.

• Journal of Korean society of Dental Hygiene
• /
• v.17 no.5
• /
• pp.769-777
• /
• 2017

Objectives: The study was to promote patient safety by analyzing the effect of dental hygienist's perception of patient safety culture on infection control activities. Methods: The study is based on a survey of 377 dental hygienists in total working in dental settings. The questionnaire consisted of 119 questions, including 34 questions on perception of patient safety culture, and 85 questions on infection control activities. Hierarchical regression analysis was used to examine the relationship between the perception of patient safety culture and infection control activities. The data was analyzed using the SPSS version 20.0, and p<0.05 was adopted to decide on significance. Results: The longer dental hygienists have worked n the dental settings, the more active they become in infection control activities. Among the different types of dental care settings, general (university) hospitals had the largest number of infection control activities, followed by dental clinics, and network dental clinics, in descending order. The dental settings possessing a higher number of dental hygienists were found to conduct more infection control activities than other dental settings. In addition, it was found that when a dental setting adopts a patient safety policy across all the units in the hospital, more systems and procedures for patient safety tend to be established, and that stricter management response to error leads to improvement of infection control activities. Conclusions:In order to enhance infection control activities, infection control activity programs should develop and implement periodic reinforcement of infection control education. regular monitoring of infection control activities.

• Journal of Korean society of Dental Hygiene
• /
• v.21 no.3
• /
• pp.291-300
• /
• 2021

Objectives: This study aimed to develop human rights indicators through reliability and validity tests in order to measure the human rights situation of dental hygiene students who experience clinical practice at dental clincs. Methods: The basic framework of questions was constructed through literature review. Nine experts were tested for validity of the contents of the experts twice. The main survey was conducted on 121 students in the 3rd and 4th grade who were enrolled in the department of dental hygiene located in Seoul, Gyeonggi and Gangwon-do. Validity was tested through exploratory factor analysis, and reliability was tested through internal reliability coefficient and test-retest method. Results: The cronbach's α value was 0.734, and the Kappa coefficient was 0.584. The result of the reliability and validity test was composed of 11 questions and 3 factors. Conclusions: During the practice of a dental institution, the validity and reliability of the indicators that can grasp the human rights status of dental hygiene students were tested. It is expected that the indicators of this study will be provided an opportunity to understand the human rights situation of dental hygiene students and to improve problems such as human rights violations.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.24 no.4
• /
• pp.297-299
• /
• 2024

• Journal of Periodontal and Implant Science
• /
• v.34 no.4
• /
• pp.819-836
• /
• 2004

Nowdays, the awareness of implant treatment has grown rapidly among dentists and patients alike in Korea, as it becomes a widely accepted treatment. The reason is that unlike crown and bridge or denture treatment, implant treatment helps preserve existing bone and improve masticatory functions. So, It is needed understanding about the type, distribution of implant patient. The following results on patient type and implant distribution were compiled from 4433 implant cases of 1596 patients treated at the periodontal dept. of Y University Hospital during 1992 to 2004. 1. There are no dissimilarities between men and women, with patients in their 40, 50s accounting for 52.5% of patients and 57.5% of implant treatments; the largest share of patients and implant treatments. 2. Mn. posterior area accounted for 54.9% of implant treatments followed by Mx. posterior area(27.6%), Mx anterior area(11.9%) and Mn anterior area(5.6%). 3. Partial edentulous patients treated by single crown and bridge-type prosthesis accounted for 97.5% and fully edentulous patient accounted for the remaining 2.5%. 4. The major cause of tooth loss is periodontal disease, followed by dental caries, trauma and congenital missing. Also, older people are more likely to suffer from tooth loss due to periodontal disease rather than dental caries. 5. In the distribution of bone quality for maxillae, type III was most, followed by type II, r type IV and r type I. As for mandible, type II was most, followed by type III, type IV and for type I. 6. In the distribution of bone quantity for maxillae, type C was most, followed by type B, type D, type A, and for type E. As for mandible, type B was 52% most, followed by type C, type D, type A and type E. 7. The majority of implants were those of 1O-14mm in length (85.2%) and regular diameter in width (64%). The results provided us with basic data on patient type, implant distribution, bone condition, etc. We wish that our results coupled with other research data helps assist in the further study for better implant success/survival rates, etc.

• Child Health Nursing Research
• /
• v.15 no.2
• /
• pp.201-209
• /
• 2009

Purpose: This quasi-experimental study was conducted to identify the effects of dental health education on dental health knowledge and dental hygiene status in preschoolers. Methods: Forty-one children were recruited from two daycare centers, one of which served as the experimental group and the other as the comparative group without dental health education. Dental health education consisted of knowledge-oriented lecture and individual practice with a tooth simulator. The dental health knowledge was measured using a self-report questionnaire and dental hygiene using a dental plague index. The measurements were taken before and after the education program in the experimental group while only before the education program in comparative group. Results: Increases in dental health know ledge and decreases in dental plague index were observed 4 days after the education and lasted at least 8 days after the education, Conclusion: The findings of this study indicate that dental health care education consisting of a lecture with simulation practice can be effective in improving dental health care in preschoolers at day care center.

• Journal of Korean society of Dental Hygiene
• /
• v.22 no.3
• /
• pp.209-216
• /
• 2022

Objectives: This study was conducted to provide basic data for developing a professionalism improvement program for dental hygienists in preparation for the 4th industrial revolution era. Methods: A survey was conducted in 216 dental hygienists from May 3 to June 14, 2021, and statistical processing was performed using frequency analysis, t-test, one-way ANOVA, Pearson's correlation analysis, and multiple regression analysis. Results: Communication competence were at higher levels for dental hospital workers (3.98) and university/graduate school (3.94); professionalism was at higher levels for dental hospital workers (3.64), university/graduate school (3.55), and 7 or more dental hygienists at workplace (3.53); self leadership was at higher levels for dental hospital workers (4.11), university/graduate school (4.04), and intermediary manager (4.00); job performance was at higher levels for 11 years or more (4.08), university/graduate school (4.04), intermediary manager (4.04), and 30-34 years of age (4.04). There was positive correlation among communication competence, professionalism, self-leadership, and job performance. Factors affecting job performance were self-leadership (β=0.461), communication competence (β=0.353), 30-34 years of age (β=0.141), and total experience of 8-10 years (β=-0.149). Conclusions: In the era of the 4th industrial revolution, it is necessary to develop a program to strengthen the professional competence of dental hygienists.

• Journal of Korean society of Dental Hygiene
• /
• v.23 no.4
• /
• pp.277-286
• /
• 2023

Objectives: In this study, we aimed to develop a systematic tool that can evaluate the effects of interprofessional education (IPE) by applying four core competencies (values/ethics for interprofessional practice, roles/responsibilities, interprofessional communication, and teams and teamwork) and an educational evaluation model to evaluate the learning, behavior of learners, and results step by step. Methods: Previous studies on IPE evaluation tools were analyzed, and an evaluation tool (draft) was developed by modifying questions suitable for evaluation according to the Kirkpatrick model's stages and core competencies. The evaluation tool was completed by conducting a Delphi survey twice with 4-6 experts. To analyze the Delphi survey, the content validity index (CVI) was calculated, and the reliability coefficient (Cronbach's alpha coefficient) was used to measure reliability. Results: 29 questions on pre-education, consisting of learning and behavior stages, and 54 questions on post-education, consisting of reaction, learning, behavior, and results stages, were developed. The CVI and Cronbach's alpha coefficient values were >0.8 and >0.6, respectively. Conclusions: The IPE evaluation tool developed in this study is expected to contribute to the evaluation of the educational level of IPE and the identification of points for improvement when applied to various educational settings.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.39
• /
• pp.16.1-16.6
• /
• 2017

Background: Mandibular reconstruction is performed after segmental mandibulectomy, and precise repositioning of the condylar head in the temporomandibular fossa is essential for maintaining preoperative occlusion. Methods: In cases without involvement of soft tissue around the mandibular bone, the autopolymer resin in a soft state is pressed against the lower border of the mandible and buccal and lingual sides of the 3D model on the excised side. After hardening, it is shaved with a carbide bar to make the proximal and distal parts parallel to the resected surface in order to determine the direction of mandibular resection. On the other hand, in cases that require resection of soft tissue around the mandible such as cases of a malignant tumor, right and left mandibular rami of the 3D model are connected with the autopolymer resin to keep the preoperative position between proximal and distal segments before surgical simulation. The device is made to fit the lower border of the anterior mandible and the posterior border of the mandibular ramus. The device has a U-shaped handle so that adaptation of the device will not interfere with the soft tissue to be removed and has holes to be fixed on the mandible with screws. Results: We successfully performed the planned accurate segmental mandibulectomy and the precise repositioning of the condylar head by the device. Conclusions: The present technique and device that we developed proved to be simple and useful for restoring the preoperative condylar head positioning in the temporomandibular fossa and the precise resection of the mandible.