• 대한치과의사협회지
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• 제22권5호통권180호
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• pp.417-422
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• 1984

• Journal of Periodontal and Implant Science
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• 제5권1호
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• pp.14.2-14.2
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• 1975

• 대한치과의사협회지
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• 제39권12호통권391호
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• pp.1056-1060
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• 2001

• Journal of Periodontal and Implant Science
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• 제2권1호
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• pp.6.2-6.2
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• 1972

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권1호
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• pp.40-44
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• 2000

The most proper antibiotic must be selected after antimicrobial susceptibility test. If difference in antimicrobial susceptibility was significant between oral sampling sites, it is rationale to use the most susceptible antibiotic agent respond to dental procedure and object of treatment. This study examined sampling site variation from saliva, supragingival plaque and subgingival plaque of 16 children's oral microbes. The cultured bacterial isolates, which were Streptococcus viridans and Neisseria, were examined for 10 antimicribial drugs with the Bauer-Kirby agar disk diffusion method. The used drugs were Penicillin, Ampicillin, Oxacillin, Cephalothin, Imipenem, Gentamicin, Erythromycin, Vancomycin, Ciprofloxacin, Clindamycin. There was no significant difference between three sampling sites for antimicrobial susceptibility test of S. viridans and Neisseria and the sequence of susceptibility was agreed among them. In conclusion, it was suggested that antimicrobial susceptibility test from saliva, supragingival plaque and subgingival plaque of children have no significant sampling site variation.

• 치위생과학회지
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• 제15권2호
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• pp.220-225
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• 2015

본 연구에서는 국내에서 권장하고 있는 회전법이 실천 용이하고 치면세균막 제거에 효과적인지 다른 칫솔질 방법과 비교해 보고, 집단칫솔질교육 후 시간흐름에 따른 효과추이를 확인하고자 임의 추출한 20대 대학생을 대상으로 O'leary 지수와 PHP 지수를 구하고 칫솔질 수행도를 조사하였다. 분석은 STATA 11.0을 이용하였다. 회전법과 바스법, 와타나베법의 칫솔질 방법에 따라 O'leary 지수와 PHP 지수 및 칫솔질 수행도가 차이가 있는지에 대해 조사하기 위해 1차부터 3차까지 평균을 비교한 결과 차이가 없었다. 칫솔질 교육 전인 1차, 칫솔질 교육 2주 후인 2차, 칫솔질 교육 4주 후인 3차의 O'leary 지수, PHP 지수 및 칫솔질 수행도의 차이를 확인하기 위해 비모수 표본자료에 사용하는 Kruskal-Wallis test를 수행한 결과 O'leary 지수의 경우 칫솔질 교육 전 측정 시 가장 낮은 점수를 기록하였고, 2차시기 측정치가 가장 높게 나타났다(p=0.0001). PHP 지수는 1차시기 가장 높게 나타났고, 2차시기 감소하였다가 3차시기 다시 증가하는 것으로 나타났다(p=0.0001). 칫솔질 수행도 역시 PHP 지수와 유사한 경향을 보였다(p=0.0001). 이상의 결과로 회전법이 모든 사람에게 획일적으로 권장할 만한 방법인지 좀 더 다각적인 고찰이 필요하고, 칫솔질 교육효과는 시간이 지나면서 감소되므로 지속적인 교육이 실행될 수 있도록 제도적 장치가 마련되어야 함을 알 수 있었다.

• 치위생과학회지
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• 제15권6호
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• pp.696-702
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• 2015

본 연구는 유치원에 다니는 아동 총 59명을 대상으로 Q-scan을 이용한 구강보건효과를 평가하고자 하였다. 유아용 면접설문지와 Quigley & Hein index를 측정하여 다음과 같은 결과를 얻었다. 아동의 치면세균막지수는 Q-scan을 이용한 중재군에서 12% 더 유의하게 감소한 것으로 나타났다(p<0.001). 구강보건지식은 두 집단 모두 불소에서 유의한 차이가 나타났으며(p<0.05), 대조군에서는 치아에 나쁜 음식에 대한 정답률도 유의하게 증가하였다(p<0.05). 구강보건태도에서 중재군은 모든 변수에서 유의한 차이가 나타났으며(p<0.05), 대조군에서는 정기 구강검진, 칫솔질 횟수에서 유의한 차이가 나타났다(p<0.05). 구강보건행동에서 중재군은 칫솔 잡는 법에서는 정답률이 증가하고, 알맞은 치약 짜기에서는 정답률이 감소하는 유의한 결과가 나타났으며(p<0.05), 대조군은 모든 변수에서 유의한 차이가 나타나지 않았다. 이러한 결과를 종합해 보면 Q-scan은 구강보건교육 시 아동들의 동기 부여를 위한 적절한 도구로 활용될 수 있을 것으로 생각된다.

• Journal of Korean Biological Nursing Science
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• 제17권2호
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• pp.150-158
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• 2015

Purpose: This study aimed to evaluate the effects of gargling with S-solution and gargling with A-solution on salivary pH, coated tongue, and dental plaque index in preschool children. Methods: Non-equivalent control group pretest-posttest design was used to select the participants. 99 preschool children were divided into three groups. Dependent variables were recorded at baseline, 30 minutes, and 7 days after the first treatment was given. The data were analyzed using $X^2$-test, ANOVA, and repeated measures of ANOVA. Results: There were no significant differences in dependent variables in pre-test. However, the salivary pH in the S-solution group had significantly increased after 30 minutes (p<.05) and then again 7 days (p<.01) after the first treatment. Also, the S-solution and A-solution groups had greater decrease in dental plaque index after 30 minutes and again 7 days after the first treatment (p<.001) than the control group. With respect to coated tongue, there were no significant differences among the three groups. Conclusion: The results of this study indicate that essential oil gargling after brushing is helpful in improving oral health due to auxiliary oral hygiene effects with natural products. Specifically, gargling with S-solution is more effective than A-solution on oral health in preschool children by neutralizing salivary pH and reducing dental plaque index.

• 대한치과의사협회지
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• 제15권2호
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• pp.145-151
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• 1977

The author performed Snyder test, estimation of salivary flow rate, salivary viscosity test, salivary buffering capacity test, M-R test, oral hygiene ability test, estimation of oral glucose clearance time and plaque reformation test in the 107 male Koreans aged form the age of 20 to 29, in order to detect and control the active cariogenic factors contributing to caries development on the individual basis. Thereafter, the data from 8 kinds of caries activity test were analysed and evaluated. The obtained results were as follows: 1. Snyder test was positive in 86.0% of total tested persons, and among those showing positive Snyder test reaction, slight caries activity was appeared in 39.1%, moderate caries activity in 23.9%, and marked caries activity in 37.0%. 2. Salivary flow rate was under the average flow amount in 53.3%. 3. Salivary buffering capacity was low in 22.4%. 5. Buffering capacity of dental plaque was high in 12.5%. 6. Oral hygiene ability was insufficient in all persons tested. 7. Oral glucose clearance time was long in 42.1%. 8. Plaque reformation rate was high in 8.4% of the 107 persons tested.

• Biomolecules & Therapeutics
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• 제29권3호
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• pp.263-267
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• 2021

Periodontal disease is primarily associated with bacterial infection such as dental plaque. Dental plaque, an oral biofilm harboring a complex microbial community, can cause various inflammatory reactions in periodontal tissue. In many cases, the local bacterial invasion and host-mediated immune responses lead to severe alveolar bone destruction. To date, plaque control, non-surgical, and surgical interventions have been the conventional periodontal treatment modalities. Although adjuvant therapies including antibiotics or supplements have accompanied these procedures, their usage has been limited by antibiotic resistance, as well as their partial effectiveness. Therefore, new strategies are needed to control local inflammation in the periodontium and host immune responses. In recent years, target molecules that modulate microbial signaling mechanisms, host inflammatory substances, and bone immune responses have received considerable attention by researchers. In this review, we introduce three approaches that suggest a way forward for the development of new treatments for periodontal disease; (1) quorum quenching using quorum sensing inhibitors, (2) inflammasome targeting, and (3) use of FDA-approved anabolic agents, including Teriparatide and sclerostin antibody.