• Journal of Gastric Cancer
• /
• v.5 no.3 s.19
• /
• pp.191-199
• /
• 2005

Background: Though infections of Helicobacter pylori (H. pylori) are closely associated with activation of host angiogenesis, the underlying mechanisms, as well as the strategy for its prevention, have not been identified. Here, we investigated a causal role of H. pylori infection in angiogenesis of gastric mucosa and a potent inhibitory effect of a gastric proton pump inhibitor (PPI) on the gastropathy. Materials and Methods: A comparative analysis of CD 34 expression in tissues obtained from 20 H. pylori-associated gastritis and 18 H. pylori-negative gastritis patients was performed. Expression of $HIF-1{\alpha}$ and VEGF were tested by using RT-PCR. To evaluate the direct effect of H. pylori infection on differentiation of endothelial HUVEC cells, we carried out an in vitro angiogenesis assay. Results: H. pyfori-associated gastritis tissues showed significantly higher density of $CD34^+$ blood vessels than did H. pylori-negative gastritis tissues, and the levels were well correlated with expressions of $HIF-1{\alpha}$. Conditioned media from H. pylori-infected gastric mucosal cells stimulated a tubular formation of HUVEC cells. We also found a significant inhibitory effect of PPI, an agent frequently used for H. pylori eradication, on H. pylori-induced angiogenesis. This drug effectively inhibited the phosphorylation of MAP kinase ERK1/2, which is a principal signal for H. pylori-induced angiogenesis. Conclusion: The fact that PPls can down-regulate H. pylori-induced angiogenesis suggest that anti-angiogenic treatment using PPI may be a preventive approach for H. pylori-associated carcinogenesis.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.24 no.4
• /
• pp.99-112
• /
• 2021

This study was performed to predict spatial change of future forestland area in South Korea at regional level for supporting forest-related plans established by local governments. In the study, land use was classified to three types which are forestland, agricultural land, and urban and other lands. A logistic regression model was developed using transitional interaction between each land use type and topographical factors, land use restriction factors, socioeconomic indices, and development infrastructures. In this model, change probability from a target land use type to other land use types was estimated using raster dataset(30m×30m) for each variable. With priority order map based on the probability of land use change, the total annual amount of land use change was allocated to the cells in the order of the highest transition potential for the spatial analysis. In results, it was found that slope degree and slope standard value by the local government were the main factors affecting the probability of change from forestland to urban and other land. Also, forestland was more likely to change to urban and other land in the conditions of a more gentle slope, lower slope criterion allowed to developed, and higher land price and population density. Consequently, it was predicted that forestland area would decrease by 2027 due to the change from forestland to urban and others, especially in metropolitan and major cities, and that forestland area would increase between 2028 and 2050 in the most local provincial cities except Seoul, Gyeonggi-do, and Jeju Island due to locality extinction with decline in population. Thus, local government is required to set an adequate forestland use criterion for balanced development, reasonable use and conservation, and to establish the regional forest strategies and policies considering the future land use change trends.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.51 no.2
• /
• pp.28-41
• /
• 2023

The objective of the study was to develop an Urban Windway Forest Creation Planning Technique for the Improvement of the Urban Environment using the case of Daejeon Metropolitan City. Through a spatial analysis of fine dust and heat waves, a basin zone, in which the concentration was relatively serious, was derived, and an area with the potential of cold air flow was selected as the target area for the windway forest development by analyzing the climate and winds in the relevant zone. Extreme fine dust areas included the areas of the Daejeon Industrial Complex Regeneration Business District in Daedeok-gu and Daedeok Techno Valley in Yuseong-gu. Heat wave areas included the areas of Daedeok industrial Complex in Moksang-dong, the Daejeon Industrial Complex Regeneration Business District in Daehwa-dong, and the high-density residential area in Ojeong-dong. As a result of measuring the wind speeds in Daejeon with an Automatic Weather System, the average wind speeds during the day and night were 0.1 to 1.7 m/s,, respectively. So, a plan of for a windway forest that smoothly induces the movement of cold air formed in outer forests at night is required. The fine dust/heat wave intensive management zones of Daejeon Metropolitan City were Daejeoncheon, Yudeungcheon, Gapcheon-Yudeungcheon, and Gapcheon. The windway forest formation plan case involved the old city center of Daejeon Metropolitan City among the four zones, the Gapcheon-Yudeungcheon area, in which the windway formation effect was presumed to be high. The Gapcheon-Yudeungcheon area is a downtown area that benefits from the cold and fresh air generated on Mt. Gyejok and Mt. Wuseong, which are outer forests. Accordingly, the windway forest was planned to spread the cold air to the city center by connecting the cold air generated in the Seosa-myeon forest of Mt. Gyejok and the Namsa-myeon forest of Mt. Wuseong through Gapcheon, Yudeungcheon, and street forests. After selecting the target area for the wind ventilation forest, a climate map and wind formation function evaluation map were prepared for the area, the status of variation wind profiles (night), the status of fine dust generation, and the surface temperature distribution status were grasped in detail. The wind ventilation forest planning concept and detailed target sites by type were identified through this. In addition, a detailed action plan was established according to the direction of creation and setting of the direction of creation for each type of wind ventilation forest.

• Economic and Environmental Geology
• /
• v.46 no.4
• /
• pp.301-312
• /
• 2013

Landslides are caused by complex interaction among a large number of interrelated factors such as topography, geology, forest and soils. In this study, a comparative study was carried out using fuzzy relationship method and artificial neural network to evaluate landslide susceptibility. For landslide susceptibility mapping, maps of the landslide occurrence locations, slope angle, aspect, curvature, lithology, soil drainage, soil depth, soil texture, forest type, forest age, forest diameter and forest density were constructed from the spatial data sets. In fuzzy relation analysis, the membership values for each category of thematic layers have been determined using the cosine amplitude method. Then the integration of different thematic layers to produce landslide susceptibility map was performed by Cartesian product operation. In artificial neural network analysis, the relative weight values for causative factors were determined by back propagation algorithm. Landslide susceptibility maps prepared by two approaches were validated by ROC(Receiver Operating Characteristic) curve and AUC(Area Under the Curve). Based on the validation results, both approaches show excellent performance to predict the landslide susceptibility but the performance of the artificial neural network was superior in this study area.

• Publications of The Korean Astronomical Society
• /
• v.27 no.4
• /
• pp.111-116
• /
• 2012

Far-infrared observations provide crucial data for the investigation and characterisation of the properties of dusty material in the Interstellar Medium (ISM), since most of its energy is emitted between ~ 100 and $200{\mu}m$. We present the first all-sky image from a sensitive all-sky survey using the Japanese AKARI satellite, in the wavelength range $50-180{\mu}m$. Covering > 99% of the sky in four photometric bands with four filters centred at $65{\mu}m$, $90{\mu}m$, $140{\mu}m$, and $160{\mu}m$ wavelengths, this achieved spatial resolutions from 1 to 2 arcmin and a detection limit of < 10 MJy $sr^{-1}$, with absolute and relative photometric accuracies of < 20%. All-sky images of the Galactic dust continuum emission enable astronomers to map the large-scale distribution of the diffuse ISM cirrus, to study its thermal dust temperature, emissivity and column density, and to measure the interaction of the Galactic radiation field and embedded objects with the surrounding ISM. In addition to the point source population of stars, protostars, star-forming regions, and galaxies, the high Galactic latitude sky is shown to be covered with a diffuse filamentary-web of dusty emission that traces the potential sites of high latitude star formation. We show that the temperature of dust particles in thermal equilibrium with the ambient interstellar radiation field can be estimated by using $90{\mu}m$, $140{\mu}m$, and $160{\mu}m$ data. The FIR AKARI full-sky maps provide a rich new data set within which astronomers can investigate the distribution of interstellar matter throughout our Galaxy, and beyond.

• Spatial Information Research
• /
• v.18 no.5
• /
• pp.27-36
• /
• 2010

This study observed distribution of vegetation to confirm change of tundra-taiga boundary. Tundra-taiga boundary is used to observe the transfer of vegetation pattern because it is very sensitive to human activity, natural disturbances and climate change. The circumpolar tundra-taiga boundary could observe reaction about some change. Reaction and confirmation about climate change were definite than other place. This study used Leaf Area Index(LAI) 8-Day data in August from 2000 to 2009 that acquire from Terra satellite MODerate resolution Imaging Spectroradiometer(MODIS) sensor and used K$\"{o}$ppen Climate Map, Global Land Cover 2000 for reference data. This study conducted analysis of spatial distribution in low density vegetated areas and inter-annual / zonal analysis for using the long period data of LAI. Change of LAI was confirmed by analysis based on boundary value of LAI in study area. Development of vegetation could be confirmed by area of grown vegetation($730,325km^2$) than area of reduced vegetation ($22,372km^2$) in tundra climate. Also, area was increased with the latitude $64^{\circ}$ N~$66^{\circ}$ N as the center and around the latitude $62^{\circ}$ N through area analysis by latitude. Vegetation of tundra-taiga boundary was general increase from 2000 to 2009. While area of reduced vegetation was a little, area of vegetation growth and development was increased significantly.

• Korean Journal of Environment and Ecology
• /
• v.22 no.6
• /
• pp.632-639
• /
• 2008

This paper deals with feeding site distribution aspect and seasonal distribution change of the wintering geese in Cheonsu bay and reclaimed area from October 2006 to March 2007. Geese were distributed mostly in agricultural land(rice field) during day time. According to the distribution map by maximum counts, observed geese of agricultural land were frequently distributed in large agricultural land. Especially, Geese were more used agricultural land near the reservoir where used as roosting site than the other sites. Diurnal feeding site of the geese were agricultural land near the reservoir with huge flock during early wintering season(October), but geese were used the agricultural land far from reservoir after mid wintering season(after January). The feeding flock size of Geese were decreased and feeding site was more far from the reservoir than in mid wintering season during late wintering season(March). Habitat use rate of the quadrat area where below 1km from the reservoir was most high in early wintering season. Contrary, habitat use rate where 2km far from the reservoir was shown lowest habitat use rate in early wintering season, but it was increased during mid wintering season(January) and decreased after mid wintering season. Habitat use rate of the agricultural land where 2km below and 1 km far from reservoir was shown middle rate, but it was increased until November and decreased after November. This result shown that feeding site preference of the wintering geese was affected by distance from roosting site(reservoir), and feeding site was changed as a food sources decreasing by stay time of geese flock.

• Journal of KIISE
• /
• v.44 no.9
• /
• pp.932-945
• /
• 2017

In this paper, a new hardware and software architecture for a stereo vision processing system including rectification, disparity estimation, and visualization was developed. The developed method, named LArge scale stereo matching method using Support Point Interpolation (LASPI), shows excellence in real-time processing for obtaining dense disparity maps from high quality image regions that contain high density support points. In the real-time processing of high definition (HD) images, LASPI does not degrade the quality level of disparity maps compared to existing stereo-matching methods such as Efficient LArge-scale Stereo matching (ELAS). LASPI has been designed to meet a high frame-rate, accurate distance resolution performance, and a low resource usage even in a limited resource environment. These characteristics enable LASPI to be deployed to safety-critical applications such as an obstacle recognition system and distance detection system for autonomous vehicles. A Field Programmable Gate Array (FPGA) for the LASPI algorithm has been implemented in order to support parallel processing and 4-stage pipelining. From various experiments, it was verified that the developed FPGA system (Xilinx Virtex-7 FPGA, 148.5MHz Clock) is capable of processing 30 HD ($1280{\times}720pixels$) frames per second in real-time while it generates disparity maps that are applicable to real vehicles.

• Journal of Environmental Health Sciences
• /
• v.41 no.6
• /
• pp.449-457
• /
• 2015

Objectives: In Korea, the system of management of medical waste largely relies on the incineration method. Our study aimed to identify any regional imbalances between the generation and treatment of medical waste, and provide reference data for future policy in Korea. Methods: We analyzed data on the amount of medical waste from 2,000 hospitals in 2012, 2013, and 2014 obtained from the Korea Environment Corporation. In the Arc GIS program (version 10.2.3), the addresses of hospitals and incinerators were transformed into map coordinates. The amount of waste generated by each hospital and the amount incinerated were represented by density and size of a triangle symbol, respectively. Results: As of 2014, the total amount of medical waste from the top 2,000 hospitals was 136,073 tons, out of which about half (49%) was generated in the capital area. Eleven incineration companies (three in the capital area, two in the Chungcheong Provinces area, one in the Jeolla Provinces area, and five in the Gyeongsang Provinces area) treated this waste. For the years 2012, 2013, and 2014, about 60% of the medical waste generated from the hospitals in the capital area was treated within the capital area and about 40% was transported to other areas, especially the Gyeongsang Provinces area, for treatment. On the other hand, about 90% of the medical waste incinerated in the capital area originated from the capital area. Conclusion: Our results suggest a spatial imbalance between the generation and treatment of medical waste in Korea and warrants multilateral policies, including the expansion of on-site treatment, strengthening regulation of the containment of medical wastes, promoting reductions in medical waste and more.

• Journal of the Korean earth science society
• /
• v.27 no.4
• /
• pp.416-424
• /
• 2006

Because there is no generally accepted definition of a geographic center and no completely satisfactory method to determine one, there may be as many geographic centers of a country as there are many definitions. The geographic center of an area may be defined as the center of gravity on a surface, or that point on which the surface of an area would balance if it were a plane of uniform thickness. This research uses geographic information system (GIS) analysis and there are places where it defines the geographical and the geological centers in the inland of South Korea. To compute the geo-centers in South Korea: 1) firstly, we collected existing reaserch data related to digital map data. 2)Secondly, we analyzed a geological center and data collection examples of Korea and other nations-the Europe and America. 3) Thirdly, we carried out numerous processes to build a geodatabase, short for geograhic database, so that GIS analysis and the constructed geodatabase is covered within the inland in South Korea. Where geodatabase is a kind of spatial database. 4) Fourthly, in order to determine the geographical center, we supposed that the condition of continental surface is the plane of homogeneous or irregular density. 5) Consequently, we chose a few resonable conditions and produced a variety of geographical centers that is geometric and gravitational in South Korea. As a result of the analysis, center points are massed to southern part of Chungbuk province, Korea.