• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3061-3063
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• 2016

Exploiting the immune system to abolish cancer growth via vaccination is a promising strategy but that is limited by many clinical issues. For DNA vaccines, viral vectors as a delivery system mediate a strong immune response due to their protein structure, which could afflect the cellular uptake of the genetic vector or even induce cytotoxic immune responses against transfected cells. Recently, synthetic DNA delivery systems have been developed and recommended as much easier and simple approaches for DNA delivery compared with viral vectors. These are based on the attraction of the positively charged cationic transfection reagents to negatively charged DNA molecules, which augments the cellular DNA uptake. In fact, there are three major cellular barriers which hinder successful DNA delivery systems: low uptake across the plasma membrane; inadequate release of DNA molecules with limited stability; and lack of nuclear targeting. Recently, a polysaccharide polymer produced by microalgae has been synthesized in a form of polymeric fiber material poly-N-acetyl glucosamine (p-GlcNAc). Due its unique properties, the F2 gel matrix was suggested as an effective delivery system for immune and gene vaccinations.

• IEMEK Journal of Embedded Systems and Applications
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• v.19 no.1
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• pp.33-38
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• 2024

In this paper, we propose the implementation of a drone delivery system using artificial intelligence in a situation where the use of drones is rapidly increasing and human errors are occurring. This system requires the implementation of an accurate control algorithm, assuming that last-mile delivery is delivered to the apartment veranda. To recognize the delivery location, a recognition system using the YOLO algorithm was implemented, and a delivery system was installed on the drone to measure the distance to the object and increase the delivery distance to ensure stable delivery even at long distances. As a result of the experiment, it was confirmed that the recognition system recognized the marker with a match rate of more than 60% at a distance of less than 10m while the drone hovered stably. In addition, the drone carrying a 500g package was able to withstand the torque applied as the rail lengthened, extending to 1.5m and then stably placing the package down on the veranda at the end of the rail.

• Journal of Distribution Science
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• v.18 no.4
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• pp.39-50
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• 2020

Purpose: This paper aimed to study the current locations of post offices to analyze service coverage area for parcel delivery in the Eastern Economics Corridor (EEC), which must be considered in the last mile to extend delivery service for e-commerce growth. Thailand Post was the case study in this paper. Research design, data and methodology: To involve solving the delivery service area under the last mile condition, the authors proposed a network analysis to determine service radius by employing a Geographic Information System (GIS). Furthermore, this paper applied Dijkstra's algorithm as a network analysis tool from GIS for analyzing the last mile service coverage area in a new economics zone. At the same time, the authors suggested an approach as a solution to locate last mile delivery center in EEC. Results: The results of the study pointed out that Thailand Post should consider more last mile delivery centers in EEC to support its express service in urban areas as well as improve the efficiency of service coverage for parcel delivery and create more advantages against competitors. Conclusions: This paper proposes a network analysis to extend the last mile service for parcel delivery by following Dijkstra's algorithm from GIS and a solution approach to add more last mile delivery centers. The results of the research will contribute to boosting customer satisfaction for last mile delivery service and enabling easy accessibility to a service center in EEC.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.307-307
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• 2003

Strategies to make finished products more stable and efficacious can take advantage of formulation technologies- ingredients and techniques - to improve their delivery into the skin by both enhanced penetration and delayed release. Nanometer range particles and emulsion droplets can be formed with a selection of either silicone copolyol or conventional organic surfactants and dispersion shear rates sufficient to generate stable submicron droplets. By incorporating these into systems with biomimetic liquid crystalline gel networks in either simple or multiple phase emulsions the skin delivery can be enhanced as shown in tape stripping experiments. Such systems can stabilize labile actives, such as Vitamin C and retinol, and aid delivery. Laboratories in U.S and Europe investigated actives including green tea polyphenols, salicylic acid and methyl and benzyl nicotinate.

• Journal of Information Processing Systems
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• v.10 no.1
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• pp.81-91
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• 2014

Widely spreading smart devices have become an important information sharing channel in everyday life. In particular, social networking services (SNS) are the hub for content creation and sharing. Users post their contents on SNS servers and receive contents of interest. Contents are delivered in either pull or push. Regarding delivery, cost and wait time are two important factors to be minimized, but they are in a trade-off relationship. The Push-N-scheme (PNS) and timeout-based push scheme (TPS) have been proposed for content delivery. PNS has an advantage in cost over TPS, whereas TPS has an edge in terms of the wait time over PNS. We propose a hybrid push scheme of PNS and TPS, called push-N-scheme with timeout (PNT), to balance the cost and the wait time. We evaluate PNT through simulations, with the results showing that PNT is effective in balancing PNS and TPS.

• Medical Lasers
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• v.9 no.1
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• pp.6-11
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• 2020

Hydrogels have been developed and used in tissue engineering and regenerative medicine to deliver therapeutics to injured or diseased tissue because of their versatility and properties that can be tailored to match the natural extracellular matrix. Hydrogels can be made with a variety of physical and chemical properties combined with light responsiveness ideal for applications in different fields of medicine that require the spatiotemporal control of therapeutics. Light, as a stimulus, is relatively inexpensive, contact-free, noninvasive with high spatial resolution and temporal control, convenient and easy to use, and allows deep tissue penetration that is relatively harmless. Photoresponsive hydrogels are ideal candidates for on-demand drug delivery systems that are capable of sustained and controlled drug release, minimizing the side effects, and ensuring the activity and efficient delivery of drugs to the target tissue.

• Asia pacific journal of information systems
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• v.32 no.2
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• pp.354-380
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• 2022

This study proposed a novel model to investigate influential factors affecting the intention to continue using increasingly popular food delivery apps (FDAs). The proposed theoretical model is developed and validated to extend traditional technology acceptance and adoption theories by identifying several determinant factors that capture the unique context of FDAs continuous usage. Hypotheses were tested using a partial least square structural equation modeling approach (PLS-SEM) on data collected from 331 actual FDAs users during the COVID-19 pandemic. The results reveal that convenience, perceived compatibility, delivery experience, and online reviews significantly influence the continuous usage of FDAs. The findings also confirm the importance of continuous intention on the actual use of FDAs. The research model of this study explains 65% of variance in continuous intention and 47% in actual use. The insights provided by this study suggest fruitful directions for future research. They can also help FDAs companies, developers and marketers with strategies and tips for further development and growth by ensuring users' continuous usage of these platforms.

• Journal of Korea Society of Industrial Information Systems
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• v.22 no.5
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• pp.85-100
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• 2017

The Delivery Companies are Facing the Difficulty in their Delivery Services due to the Continuously Increasing Delivery Demand and Insufficient Supply of Delivery Persons to Satisfy the Demand. In Such Circumstances, the Delivery Companies have been Implementing the CSV Service by Introducing the Senior Parcel Delivery Service Creating Jobs for Senior Citizens. This Paper Investigated the Impact of the Quality of Senior Parcel Delivery Service, CSV Activities, and Individual Characteristic Factors of Consumers on the Customers' Confidence and Intention to Use the Delivery Service of Delivery Companies. For the Empirical Analysis, the Online/Offline Questionnaire Survey was Executed with the Individuals who used the Delivery Service and 216 Samples were Finally Selected for Empirical Analysis. In Accordance with the Analysis Results, the Speed, the Quality of Senior Parcel Delivery Service, had Significant Impact on the Customers' Confidence, but Safety had no Significant Impact on it. Next, the Sincerity of CSV Activity by Senior Parcel Delivery Service Companies Showed the Significant Impact on the Customers' Confidence. However, the Adequacy of CSV Activity had No Significant Impact on the Customers' Confidence. Furthermore, the Consumption Value and Ethical Consumption Propensity, the Individual Features of Consumers, Demonstrated the Significant Impact on the Customers' Confidence and also on the Customers' Confidence on and their Intention to use Senior Parcel Delivery Service Companies.

• Journal of Korean Library and Information Science Society
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• v.16
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• pp.191-220
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• 1989

This study is an attempt to furnish some helpful data for the design and implementation of the electronic document delivery system based on the analysis of it's cases. To begin with, the concepts and basic models of electronic document delivery system(Fig. 1) were overviewed in the second chapter, on the basis of which the concrete cases were introduced in the third chapter ; ADONIS Project, ARTEMIS Project, HERMES Project, APOLLO Project, UNIVERSE Project, DOCDEL Project, and etc. In the future rapidly developed the technology of electronic communication, there are many possibilities of the evolution of electronic document delivery system.

• Journal of Pharmaceutical Investigation
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• v.32 no.4
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• pp.241-258
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• 2002

Such osmotic drug delivery systems are based on osmosis, the diffusion of water transversely from a medium with a low osmotic pressure to a medium with a high osmotic pressure for the controlled delivery of active agents. In this review, U.S. Patents on osmotic drug delivery analyze 261 patents until December 2001. These devices form now a major market of drug delivery products. Because of their advantage and innovate idea, it appears that the future of oral drug delivery mark,εt in Korea is promising.