• Title/Summary/Keyword: Delivery systems

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Evaluation of Flow-Pollutant Load Delivery Ratio Equations on Main Subwatersheds within Juam Lake (농촌유역 유량-유달율 단순회귀식을 이용한 주암호 상류유역의 유달율 추정가능성 평가)

  • Jung, Jae-Woon;Lim, Byung-Jin;Choi, Dong-Ho;Choi, Yu-Jin;Lee, Kyoung-Sook;Kim, Young-Joo;Kim, Kap-Soon;Chang, Nam-Ik;Yoon, Kwang-Sik
    • Journal of Environmental Science International
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    • v.21 no.10
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    • pp.1235-1244
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    • 2012
  • The objective of this study is to evaluate Flow-Pollutant load delivery ratio equations developed from rural watershed on main subwatersheds within Juam Lake. Two regression equations for BOD and three equations for T-P were evaluated on Bosung cheon, Dongbok cheon, Songgwang cheon, Naenam cheon, and Sinpyeon cheon. The results show that estimation of BOD delivery ratio using flow-delivery equation is reliable when relative composition of discharge load of pollutant sources of a watershed is similar to those of watershed where the equation developed. On the other hand, application of regression equation for T-P was feasible when the landuse pattern and relative composition of discharge load of pollutant sources of a watershed is similar to those of watershed where the equation developed.

Project Delivery Systems and Project Performance;An Evaluation Model for Public Construction Projects (공공건설사업의 발주방식 선정 및 성과평가 모델)

  • Yu, Il-Han;Kim, Kyung-Rai
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.41-47
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    • 2007
  • The selection of the reasonable project delivery system (PDS) is crucial for a successful performance of a project, which means to achieve project objectives. Furthermore, the project performance has been tightly related to the selection of PDS appropriate to pertinent project characteristics. In this context, the ministry of finance and economy of Korea launched two new project delivery systems called "Best Value Contract (Design-Bid-Build)" and "Bridging Contract (Design-Build)" in October of 2007 by revising enforcement ordinances of "Act on Contracts to Which the State is a Party". For efficient operation of the new project delivery systems, this paper suggested a PDS selection model which supports decision making of the reasonable PDS for a pertinent project by assessing characteristics of the public construction projects, both quantitatively and qualitatively. In addition, a PDS performance evaluation model was proposed in order to get feedback on the result of the PDS selection and the operation for the succeeding project. The standard models suggested in this paper might be used as a tool to support the decision making of the public organizations.

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On the Needs of Vertical and Horizontal Transportation Machines for Freight Transportation Standard Containers to Derive Design Requirements Optimized for the Urban Railway Platform Environment

  • Lee, Sang Min;Park, Jae Min;Kim, Young Min;Kim, Joo Uk
    • International Journal of Internet, Broadcasting and Communication
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    • v.13 no.4
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    • pp.112-120
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    • 2021
  • Recently, the number of consumers using digital online distribution platforms is increasing. This caused the rapid growth of the e-commerce market and increased delivery volume in urban areas. The logistics system, designed ar006Fund the city center to handle the delivery volume, operates a delivery system from the outskirts of the city to the urban area using cargo trucks. This maintains an ecosystem of high-cost and inefficient structures that increase social costs such as road traffic congestion and environmental problems. To solve this problem, research is being conducted worldwide to establish a high-efficiency urban joint logistics system using urban railway facilities and underground space infrastructure existing in existing cities. The joint logistics system begins with linking unmanned delivery automation services that link terminal delivery such as cargo classification and stacking, infrastructure construction that performs cargo transfer function by separating from passengers such as using cargo platform. To this end, it is necessary to apply the device to the vertical and horizontal transportation machine supporting the vertical transfer in the flat space of the joint logistics terminal, which is the base technology for transporting cargo using the transfer robot to the destination designated as a freight-only urban railway vehicle. Therefore, this paper aims to derive holistic viewpoints needs for design requirements for vertical and vertical transportation machines and freight transportation standard containers, which are underground railway logistics transport devices to be constructed by urban logistics ecosystem changes.

Smart Polymeric Micelles as Nanocarriers for Gene and Drug Delivery

  • Kataoka, Kazunori
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.54-55
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    • 2006
  • Polymeric micelles, supramolecular assemblies of block copolymers, are useful nanocarriers for the systemic delivery of drugs and genes. Recently, novel polymeric micelles with various functions such as the targetability and stimuli-sensitivity have been emerged as promising carriers that enhance the efficacy of drugs and genes with minimal side effects. This presentation focuses our recent approach to the preparation of functional block copolymers that are useful for constructing smart micellar delivery systems in advanced therapeutics, including chemo-gene therapy. Particular emphasis is placed on the characteristic behaviors of intracellular environment-sensitive micelles that selectively exert drug activity and gene expression in live cells.

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The Current Status of Adenovirus-based Cancer Gene Therapy

  • Shirakawa, Toshiro
    • Molecules and Cells
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    • v.25 no.4
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    • pp.462-466
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    • 2008
  • Adenoviruses are the most commonly used gene-delivery vectors due to the efficiency of their in vivo gene transfer. Since 1993, about 300 protocols using an adenoviral vector have been performed, although they have yet to be proven effective in clinical trials. The adenovirus-based vector has been continuously improved by modification of the adenoviral genome and capsid, and novel adenovirus-delivery systems, such as the carrier-cell delivery system, have been recently proposed. Adenovirus-based cancer gene therapy is fast becoming one component of a multi-modality treatment approach to advanced cancer, along with surgery, radiotherapy, and chemotherapy.

Electrospun poly (lactic-co-glycolic acid)(PLGA) nanoparticles for controlled drug delivery system

  • Lee, Jue-Yeon;Lee, Meong-Hee;Park, Won-Ho;Min, Beong-Moo;Lee, Seung-Jin
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.227.2-228
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    • 2003
  • In many biodegradable polymers recently investigated, poly(lactic acid)(PLA) or poly(lactic-co-glycolic acid)(PLGA) have extensively been utilized as drug delivery systems for sustained release drug delivery. Recently, there has been increased interest in electrospinning, which can produce fibers that are sub-micron in diameter. This technique has been applied to various micro/nano fabrication areas using numerous polymers but very few uses in the sharmaceutical area have been reported. (omitted)

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Application of in situ gelling mucoadhesive delivery system for plasmid DNA as a macromolecule

  • Park, Jeong-Sook;Oh, Yu-Kyoung;Kim, Chong-Kook
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.236.1-236.1
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    • 2002
  • Mucosal administration of drug or therapeutic gene is emerging as a new route of delivery for systemic and local therapeutics. Previously. in situ gelling system has been applied to chemical drug such as acetaminophen. insulin. prostaglandin E1. and clotrimazole. Plasmid DNA has not been delivered in form of in situ gelling vehicles. To improve the intranasal absorption of plasmid DNA. we designed delivery systems composed of provide of in 냐셔 gelling and mucoadhesive polymers. (omitted)

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Web-based Information Systems and Service Quality of IS Department

  • Lee Woongkyu
    • Proceedings of the Korea Association of Information Systems Conference
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    • 2003.05a
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    • pp.169-181
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    • 2003
  • As growth of the web-based applications, the requirements of the users who have been very familiar to the web-based user interfaces and customer-oriented services on the Internet would become more knowledge-intensive and higher technology involved in a more convenient and polite way of service delivery. Therefore, the service quality of information system department should be considered as a very important factor influencing success of information systems. The objective of this study is to provide the relationship between service quality of IS department and its impacts such as use, user satisfaction and job performance. For this purpose, we provide a research model for it and test it empirically for the users of the corporate portal in one of main telecommunication service providers in Korea. In result, our model with satisfiable validity and reliability shows not only importance of IS departments' service quality but also two-faced characteristics of service quality. That is, while technical competence which means with knowledge and expertise of IS department staffs is more related with user satisfaction on information systems, personal service which means the way and manner of service delivery is more related with use of it.

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A Knowledge-Based CAD System for Delivery Design in Injection Molding (사출성형에 있어서 유동주입기구 설계를 위한 지식형 CAD 시스템)

  • 이찬우;허용정
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2001.04a
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    • pp.723-726
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    • 2001
  • The design of delivery system is one of the most important subject in injection molding. Delivery system is a channel to flow the polymer melt from the injection molding machine to the mold cavities and affect quality and productivity of the part. The synthesis of delivery system of injection molding has been done empirically, since it requires profound knowledge about the moldability and causal effects on the properties of the part, which are not available to designers through the current CAD systems. A knowledge-based CAD system is constructed by adding the knowledge module to an existing geometric modeler and contains knowledge to permit non-experts ad well as mold design experts to generate the acceptable geometries of gate and runner for injection molded parts.

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Nanocellulose Applications for Drug Delivery: A Review

  • Lee, Seung-Hwan;Kim, Hyun-Ji;Kim, Jin-Chul
    • Journal of Forest and Environmental Science
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    • v.35 no.3
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    • pp.141-149
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    • 2019
  • Nanocellulose, which can exist as either cellulose nanocrystals or cellulose nanofibrils, has been used as a biomaterial for drug delivery owing to its non-immunogenicity, biocompatibility, high specific area, good mechanical properties, and variability for chemical modification. Various water-soluble drugs can be bound to and released from nanocelluloses through electrostatic interactions. The high specific surface area of nanocellulose allows for high specific drug loading. Additionally, a broad spectrum of drugs can bind to nanocellulose after facile chemical modifications of its surface. Controlled release can be achieved for various pharmaceuticals when the nanocellulose surface is chemically modified or physically formulated in an adequate manner. This review summarizes the potential applications of nanocelluloses in drug delivery according to published studies on drug delivery systems.