• Title/Summary/Keyword: Delivery loading

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The Revision of Transit Clause in the Institute Cargo Clauses (협회적하약관(ICC)상 운송조항(Transit Clause)의 변천과정에 관한 연구)

  • Lee, Jay-Bok
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • 제43권
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    • pp.337-370
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    • 2009
  • The Joint Cargo Committee of International Underwriting Association of London (IUA) and Lloyd’s Market Association (LMA) have issued the revised version of Institute Cargo Clauses A, B, C, Institute Cargo Clauses (Air) and their accompanying War and Strikes Clauses. The Institute Cargo Clauses ("ICC") were last revised in 1982. Following a two year long consultation process, the latest edition of the ICC clauses became available to the Market on 1st January 2009. The overall result of the amendments to the 1982 ICC has been to create clearer policies that are more favourable to the Assured. Exclusions have also been amended to the advantage of the assured. The Transit Clause has seen a large revision, again more favourable to the Assured. The insurance now attaches within the warehouse or place of storage when the goods are "first moved$\cdots$ for the purpose of the immediate loading into or onto the carrying vehicle or other conveyance for the commencement of transit" whereas previously the insurance would not attach until the goods left the warehouse. Furthermore, the insurance now terminates on completion of unloading from the vessel at (rather than delivery to) the final warehouse or at a warehouse prior to the destination named in the contract of insurance which the Assured or their employees elect to use either for storage or distribution.

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Preparation of Nanoparticles in Drug Delivery System Using Guar Derivatives and Dialysis Method

  • Na, Kun;Kim, Yu-Eun;Lee, Ki-Young
    • Journal of Microbiology and Biotechnology
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    • 제9권1호
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    • pp.50-55
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    • 1999
  • To develop a new form of controlled release dosage for administering for indomethacin (IND), two formulations of IND-loaded nanoparticles were designed based on polysaccharide (guar) derivatives. Nanoparticles prepared by the dialysis method were characterized with respect to morphology, size distribution, drug content, and in vitro drug release. Morphological studies by scanning electron microscopy (SEM) indicated that guar acetate (GA) nanoparticles were spherical in shape and had a smooth surface. The particle size distributions of formulation I (40mg of GA) and formulation II (80mg of GA) were shown to be $250.78\pm185.13nm$ and $718\pm145.90nm$ in distilled water ($20$^{\circ}C$), respectively. The drug loading efficiencies of nanoparticles were approximately 26% and 31% for formulations I and II, respectively. The differential scanning calorimetry (DSC) results indicated that the IND was perfectly distributed within GA nanoparticles. We also found, from the X-ray diffractometry analysis, that a decrease in the degree of crystallinity of the drug occurred in the nanoparticles. No changes between the original IND and the released IND from GA nanoparticles were detected by FT-IR. Using guar acetate, it is possible to design nanoparticles which allow the controlled release of IND over an extended period of time.

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THE PERFOMANCE OF GROUNDBASE MOBILE PLATFORM FOR C-BAND MICROWAVE SCATTEROMETER SYSTEM

  • Aziz H.;Mahmood N.N.;Ali A.;Jamil H.;Mahmood K.A.;Ahmad Z.;Ibrahim N.;Brevern P.V.;Chuah H.T.;Koo V.C.;Sing L.X.
    • Proceedings of the KSRS Conference
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    • 대한원격탐사학회 2004년도 Proceedings of ISRS 2004
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    • pp.61-63
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    • 2004
  • The procurement of a mobile microwave scatterometer platform involved the consideration to ensure a mobile platform and equipment selected full-filled technical requirement and safety standard in Malaysia. Designing, and modification works involved engineering methodology in determining and selecting a suitable hydraulic telescopic boom that suit a selected mobile platform available locally. The mobile platform is a delivery system for microwave remote sensing microwave scatterometer and other accessories to any locations in Malaysia. Total loading to be carried by the mobile platform is 4500 kg and its overall weight must be 16,000 kg as recommended by hydraulic telescopic boom manufacturers. The telescopic boom will elevate microwave scatterometer system including the antenna to a maximum height of 27 m, and can also be rotated through $3600^{\circ}$. A mechanism is incorporated in the system to enable tracking or monitoring angular movement of the hydraulic telescopic boom when positioned towards predetermined target.

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Anticancer Loaded Multi-wall Carbon Nanotube for Targeting Tumors

  • Wang, Wenping;Choi, Jung-Il;Kang, Sang-Soo;Nam, Tae-Hyun;Khang, Dong-Woo
    • Proceedings of the Materials Research Society of Korea Conference
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    • 한국재료학회 2011년도 춘계학술발표대회
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    • pp.52.2-52.2
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    • 2011
  • Flat form technology for constructing anticancer loaded multi-walled carbon nanotubes (mwCNTs) was introduced in this study. Conventional anticancer drugs, such as MTX (Methotrexate), cisplatin, DOX (Doxorubicin hydrochloride), DAU (Daunorubicin) and EPI (epirubicin) were bio-conjugated with folic acid (FA) for selective targeting tumor cells. Loading efficiencies of the used anticancer drugs on mwCNTs have shown different order of bindings depending on the molecular bind affinity of NH (amine) formation on mwCNTs. MTT assays have shown increased selective target efficiency of FA conjugated mwCNTs on breast cancer cell growth inhibition. All results collectively indicated promising application of mwCNTs as a smart inorganic nanomaterial for selective targeting drug delivery vehicle at tumor tissues.

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Effect of pH-dependent Solubility on Release Behavior of Alginate-Chitosan Blend Containing Activated Carbon

  • Oh, Ae-Ri;Jin, Dong-Hwee;Yun, Ju-Mi;Lee, Young-Seak;Kim, Hyung-Il
    • Carbon letters
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    • 제10권3호
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    • pp.208-212
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    • 2009
  • Alginate-chitosan blend containing coconut-based activated carbon was prepared as a drug delivery carrier in order to improve the loading and releasing capacity of the drug. The activated carbon was incorporated as effective adsorbent for drug due to the extremely high surface area and pore volume, high adsorption capacity, micro porous structure and specific surface activity. Alginate-chitosan blend containing coconut-based activated carbon showed the sustained release for a longer period. Alginate-chitosan blend showed higher release of drug as the pH increased and higher release of drug as the content of chitosan decreased due to the pH-dependent solubility of blend components.

Research Through Empirical Analysis on SCM Efficiency Aspects of Retail Ready Packaging System

  • Jung, Sung-Tae;Kim, Ji-Hyun
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • 제26권2호
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    • pp.85-92
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    • 2020
  • In this study, the relationship between packaging design and logistics efficiency raised in prior research was to be conducted through empirical analysis in terms of SCM efficiency. The main research contents were carried out in the pursuit of efficiency of the relevant store operation, relationship with SCM efficiency aspects, resolution of differences in recognition between manufacturers and distributors, establishment of automated systems for RRP production facilities and processes in the manufacturer's facilities, logistics costs, environment and quality safety, and promotion of RRP through the manufacturer's packaging system. As a result of the verification of SCM efficiency aspects through this study, logistics efficiency will be reduced in the case of the packaging system or delivery system, where only the operational efficiency of the store is the top priority(χ2 = 178.500, p < 0.001). This is because of the strong interaction between packaging and supply chain activities, many packaging systems affect the performance criteria of the supply chain, and the content that packaging personnel should ensure that the packaging system meets other essential requirements while meeting the primary goal of protecting the product is also a result consistent with the preceding study. An analysis of whether the RRP promotion through the manufacturer's packaging system would result in improved loading efficiency showed that there was a statistically meaningful difference at a significant level of 0.000, as χ2 = 140.133.

A Study on the Time-Dependent Deformation Behaviors of PMMA in Nanoindentation Process for Hyperfine Pit Structure Fabrication (극미세 점 구조체 제작을 위한 나노압입 공정에서 PMMA의 시간의존적 변형거동에 관한 연구)

  • Kim Hyun-Il;Kang Chung-Gil;Youn Sung-Won
    • Journal of the Korean Society for Precision Engineering
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    • 제22권7호
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    • pp.62-70
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    • 2005
  • The nanoindenter and AFM have been used for nanofabrication, such as nanolithography, nanowriting, and nanopatterning, as well as measurement of mechanical properties and surface topology. Nanoscale indents can be used as cells for molecular electronics and drug delivery, slots for integration into nanodevices, and defects for tailoring the structure and properties. Therefore, it is very important to make indents of desired morphology (shape, size and depth). Indents of different shapes can be obtained by using indenters of different geometries such as a cube comer and conical and spherical tips. The depth and size of indents can be controlled by making indentations at different indentation loads. However, in case of viscoplastic viscoelastic materials such as polymethylmethacrylate (PMMA) the time dependent deformation (TDD) should also be considered. In this study, the effect of process parameters such as loading rate and hold-time at peak load on the indent morphology (maximum penetration depth, elastic recovery, transient creep recovery, residual depth pile-up height) of PMMA were studied for hyperfine pattern fabrication.

A SYSTEM DEVELOPMENT FOR ESTIMATING NON-POINT SOURCES POLLUTANT LOADS FROM WATERSHEDS USING GIS

  • Shim, Soon-Bo;Kim, Joo-Hun;Koh, Deuk-Koo
    • Water Engineering Research
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    • 제1권3호
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    • pp.223-231
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    • 2000
  • The purpose of this study is the development of a system for estimating non-point sources pollutant loads from a watershed, which enables users to get insights of pollutant load distribution in the watershed during rain as well. Based on the Geographic Information System, this non-point source pollutant loading estimation system(NSPLES) consists of three distinct models such as a distributed rainfall-runoff model, a soil loss and delivery model, and a non-point source pollutant model. It also includes GIS modules for preprocessing the input data for the models and graphical postprocessing of the model outputs. The system output aren't only the hydrograph, sedimentograph, and pollutograph at the watershed outlet, but also various maps that show the distribution of soil loss over the watershed. The developed system was applied to the two upper stream areas of Sumjin river basin, Ssangchi and Gwanchon basins, and three rainfall events for respective subbasins during 1992 and 1998 were selected for the system application. The results of this showed relatively higher corelation between observed data and simulated data, and proved the applicability of the system.

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Confirmatory Analysis of Maternal Self-Report Inventory (Maternal Self-Esteem) (모성자존감 측정도구의 검증)

  • Han, Kyung-Ja;Bang, Kyung-Sook
    • Korean Parent-Child Health Journal
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    • 제2권
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    • pp.64-82
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    • 1999
  • This study was conducted to test the reliability and validity of Maternal Self-Report Inventory that was developed by Shea and Tronick for measuring maternal self-esteem. The subjects were 154 mothers. The construct validity for the scale was tested by factor analysis with five factor loading solution based on the previous study. One item was excluded because total-item correlation was too low, so that the number of total items were twenty-five, the analysis yielded five well defined factors: confidence on the maternal role, general ability of maternal role, caretaking ability, readiness on maternal role, and feeling on the pregnancy and deli very. These five factors explained 52.38% of the variance in the maternal self-esteem. Maternal self-esteem was not affected by maternal age, educational level, occupation, religion, delivery type, or parity. The reliability of the scale was determined with Cronbach's alpha coefficient and Guttman split-half coefficient. Cronbach's alpha was .82, for 26 items, and .83 if one item was deleted. Guttman split-half cofficient was .75. In subscale analysis, Cronbach's alpha was .63~.84. In conclusion. Maternal Self-Report Inventory showed a high degree of validity and reliability, suitable in Korean mothers for measuring maternal self-esteem. In the further study, it would be necessary to compare the maternal self-esteem between mothers with normal babies and premature babies, for confirming the criterion-related validity of the inventory.

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Characteristics of Tetanus Toxoid Loaded in Biodegradable Microparticles (파상풍 톡소이드를 함유한 생체분해성 미립구의 특성)

  • 김지윤;김수남;백선영;이명숙;민홍기;홍성화
    • YAKHAK HOEJI
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    • 제44권4호
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    • pp.293-299
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    • 2000
  • Biodegradable microspheres made from poly-lactide-co-glycolide polymers have been considered as a new delivery system for single-dose vaccine. Purified tetanus toxoid (TT) was encapsulated in poly-lactide(PLA) and poly-lactide-co-glycolide (PLGA) microparticles using a solvent evaporation method in a multiple emulsion system (water-in oil-in water). The morphology of 77-loaded microparticles was spherical and the suface of them was smooth. The particle size was in a range of 2-10. Protein loading efficiency was 68-97.8%. PLGA (85:15) microparticle showed the highest efficiency. Protein release pattern was influenced by polymer molecular weight and composition. The release rate of PLA(Mw 100,000) microsphere was higher than any other microspheres. In consequence of the hydrolysis of PLGA(50:50) microspheres, environmental pH decreased from 7.4 to 5.0. The PLA, PLGA (75:25) and PLGA (85:15) microshperes showed no significant pH change. The antigenicity or n in microshperes was assayed by indirect sandwich ELISA using equine polyclonal tetanus antitoxin for capture antibody and human polyclonal tetanus antitoxin for primary antibody. The antigenicity of TT in PLA (Mw 100,000), PLGA(50:50, Mw 100,000) and PLGA (75:25, Mw 73,300) after 30 days incubation showed 54, 40.9 and 76.7%, respectively.

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