• Journal of the Korea Society of Computer and Information
• /
• v.19 no.12
• /
• pp.219-225
• /
• 2014

A Gompertz modeling, sigmoid in shape, is a widely used application for social science, natural science, engineering, and medical research to allow confident approximation and accurate analysis and has been applied to estimate an elderly population on aging of population. Due to the high toxicity of currently available drug delivery vehicles, various efforts have been made to reduce side-effects in clinical fields, but its application to preclinical and clinical studies is limited and there are some difficulties to optimize the parameters of Gompertz modeling applicable to preclinical studies. Therefore, in this study, we demonstrated the ability of sickle red blood cells loaded by hypotonic dialysis then photosensitized and light-activated ex vivo for controlled release and simultaneously optimized Gompertz function to evaluate controlled drug release properties of photosensitized sickle red blood cells to reduce pain-related treatments in cancer patients.

• Journal of Environmental Impact Assessment
• /
• v.23 no.3
• /
• pp.187-196
• /
• 2014

The objective of this study is to evaluate and analyze Osu stream watershed water environment system. The data were collected from January 2009 to December 2011 including water temperature, pH, DO, EC, BOD, COD, TOC, SS, T-N, T-P and discharge. The data were used for principle component analysis and factor analysis. The results are as followes. The primary factors obtained from both the principal component analysis and the factor analysis were BOD, COD, TOC, SS and T-P. Once principal component analysis and factor analysis have been performed with the collected data and then the results will be applied to both simple regression model and multiple regression model. The regression model was developed into case 1 using concentrations of water quality parameters and case 2 using delivery loads. The value of the coefficient of determination on case 1 fell between 0.629 and 0.866; this was lower than case 2 value which fell between 0.946 and 0.998. Therefore, case 2 model would be a reliable choice.The coefficient of determination between the estimated figure using data which was developed to the regression model in 2012 and the actual measurement value was over 0.6, overall. It can be safely deduced that the correlation value between the two findings was high. The same model can be applied to get TOC concentrations in future.

• Journal of Environmental Science International
• /
• v.22 no.5
• /
• pp.599-608
• /
• 2013

Jeju island, which is located along the moving path of typhoon, suffers from flooding and overflow by torrential rain. So abrupt runoff occurring, damages of downstream farm field and shore culturing farms are increasing. In this study, Oaedo stream, one of the mountainous streams on Jeju island, was selected as the basin of study subject and was classified into 3 sub-basins, and after the characteristics of subject basin, the soil erosion amount and the sediment delivery of the stream by land usage distribution were estimated with the use of SATEEC ArcView GIS, the sediment yield amount of 2000 and 2005 was analyzed comparatively. As a result of estimating the sediment yield amount of 2000, the three sub-basins were respectively 12,572.7, 14,080 and 157,761 tons/year. and sediment yield amounts were estimated as 35,172.9, 5,266 and 258,535 tons/year respectively in 2005. The soil erosion and sediment yield amount of 2005 using single storm rainfall were estimated high compared with 2000, but for sub-basin 2, the values rather decreased due to changes in land use, and the land coverage of 2005, since there are many classifications of land usage compared with 2000, enabling to reflect more accurate land usage condition, could deduce appropriate results. It is anticipated that such study results can be utilized as basic data to propose a direction to predict the amount of sediment yield that causes secondary flooding damage and deteriorates water quality within detention pond and grit chamber, and take action against damages in the downstream farm field and shore culturing farms.

• Journal of the Korean Society of Tobacco Science
• /
• v.31 no.1
• /
• pp.18-28
• /
• 2009

This study describes the manufacturing method of antioxidant filter and evaluate the reduction of free radical and biological activity from mainstream smoke. When we used spray-brush for the application of antioxidant solution to the filter, cv(coefficient of variation) levels of antioxidant added to filter ranged within 3 %, which means stable and constant feeding process. 0.3~0.5mg per cigarette of antioxidant were sprayed to acetate and active carbon part in the filter plug, respectively. It was considered that the use of antioxidant added filter resulted in the reduction of the gaseous compounds of free radicals from 17 % to 19 % in the mainstream smoke. Variation for removal efficiency of free radical in antioxidant filter added to acetate part was more pronounced than that of filter added to active carbon part. Smoking deliveries of tar, nicotine for the antioxidant added filters were similar when comparing to the non-antioxidant added filter, but the delivering amounts of isoprene were significantly reduced. The estimation of consumed GSH(glutathion) showed that the gaseous toxicity of the antioxidant added filter was 14 % ~ 23 % lower than that of non-antioxidant added filter. No significant differences were observed for the total taste quality in sensory evaluation.

• Journal of Preventive Medicine and Public Health
• /
• v.35 no.3
• /
• pp.263-268
• /
• 2002

Objective : This study was aiming at estimating the joint effects of various risk factors associated with uterine cervix cancer in Korea. Methods : Data obtained from a case-control study were analyzed with a multiplicative model. Results : After adjustment for age and husband's educational attainments, the family history of cervical cancer (OR=2.1, 95% CI=1.2-3.9), unstable marital status due to separation, by death or divorce, etc. (OR=2.8, 95% CI=1.7-4.6), and a large number of deliveries ($\geq$3 vs. nulliparous OR=6.5, 55% CI=1.4-29.0) increased the risk of uterine cervix cancer, Conversely, first sexual intercourse at an older age ($\geq$25 years vs. <19 years OR=0.4, 95% CI=0.2-0.6) and husband's circumcision (OR=0.7, 95% CI=0.5-1.0) decreased the risk. In the multiplicative model, the highest joint risk (OR=39.2, 95% CI 5.9-258.9) was observed in women with a family history of uterine cervical cancer, an unstable marital status, where the ex-husband was not circumcised, with 3 or more delivery experiences, and having her first sexual intercourse when younger than 19 years of age. However, women without a family history of uterine cervix cancer, married to a circumcised husband, having had her first sexual intercourse at 25 years or older, and nulliparous, showed the lowest joint effect (OR=0.3, 95% CI=0.1-0.5). Conclusion : As carcinogenesis is a complex action involving various factors, we consider a joint effects approach to be appropriate in an epidemiological study on risk factors for uterine cervix neoplasms cervix neoplasm.

• Health Policy and Management
• /
• v.28 no.3
• /
• pp.315-319
• /
• 2018

This paper aims to make a step-by-step strategy to formulate an unified health system by clarifying and overcoming challenges facing South and North Korea and to estimate costs needed for South Korea to assist North Korea to recover to normal health delivery system. We explored implications through literature review and estimated costs under the assumption that supportive activities be provided for 5 years in three ways: support for the development of health and medical care manpower; support for health and medical facilities; and support for the provision of both preventive and primary health care. Step-by-step strategy is formulated for a unified health system with the cost estimation resulting as follows: in case of basic scenario, a total of 3 trillion and 341 billion won (at present value of the year 2017) is in need for the 5-year period at the initial 'recovery support stage' with 135.9 billion won for the development of health and medical care manpower, approximately 2 trillion won for health and medical facilities, and 1.2 trillion won for the provision of both preventive and primary health care. Step-by-step approach is more realistic and applicable in formulating unified health system. Suggested stages are 'recovery support stage,' 'system homogenization stage,' and 'unified system stage.' Strategies at 'recovery support stage' suggested in this paper need to be pursued and followed by those at 'system homogenization stage' and 'unified system stage.'

• Journal of Digital Convergence
• /
• v.14 no.11
• /
• pp.233-240
• /
• 2016

Information system development projects, have a mechanism for many of the costs generated by a variety of risk factors. In general, the probability that the software project of the information system is carried out successfully in the delivery time is very low. This prediction of a formal cost is needed as the most important factor since it can prevent the project from being failed. However, objectivity of most of the project scale calculation during the calculation criteria is insufficient. Further, it is the actual situation that the management of the base line is not properly made during the project. Therefore, in this paper, we propose a model to calculate the number of steps it takes to develop on the basis of a methodology in an attempt to overcome the limitation of being unpractical in the early stage of the information system development project. It is expected to be a tool to estimate the effort and cost required by the information system development business through these convergence proposals model.

• Journal of Digital Convergence
• /
• v.12 no.3
• /
• pp.141-147
• /
• 2014

Diffusion model is popular research topic in marketing and economy particularly for the areas of model specification and market size forecasting. In particular, Bass model can explain Roger's innovation diffusion and product life cycle through easy mathematical representation and hence the model has been widely used for the explanation of adopting innovative new products and technologies. Nonetheless, there're only a couple of pioneering researches about semiconductor market, using diffusion models. Consequently, we'd utilise NLS approach diffusion model to estimate the market potential of MOSFET, major switching device for power management of system, and explain the process to industry stakeholders and policy makers for delivery of managerial implication with pragmatic purpose.

• Journal of Advanced Marine Engineering and Technology
• /
• v.38 no.4
• /
• pp.396-402
• /
• 2014

The measurement of air-borne noise in a naval ship is a crucial element. Because the noise in a naval ship interferes with a communication between crews and finally it causes to reduce the combat power. Thus, most of newly built ships have to satisfy the criteria of air-borne noise in the stage of delivery of a naval ship. In order to evaluate success or failure of criteria, uncertainty of the measurement should be considered. This study introduces the test method for the measurement of the air-borne noise in a naval ship and is concerned with the evaluation of uncertainty. The uncertainty results which was from the measurement of air-borne noise in 7 naval ships newly built satisfy the error tolerance(2dB). Therefore, it is need to reduce the error tolerance for the reliable measurement result.

• Journal of Korea Water Resources Association
• /
• v.48 no.9
• /
• pp.695-709
• /
• 2015

The inflow of nonpoint pollution sources due to sustainable development and urbanization is gradually increasing and causes a diversity of water pollution. There are lots of difficulties to find a solution as the problems related to variation of hydrological and natural phenomenon. A differentiated method to estimate the nonpoint pollution sources has been proposed using rainfall and characteristics of urbanization and observed data from sewage treatment districts in the study. The types of nonpoint pollution sources on an assumption of combined sewer system have been classified as three types which are inflow of rainfall, bypass of sewage treatments, and combined sewer overflows from a river. Three types for estimation of nonpoint pollution sources applied more accurately to generate a amount of nonpoint pollution loads. This study is expecting a wide application for effective water resource management on TMDL (total maximum delivery load) unit watershed and sewage treatment districts.