• Water Engineering Research
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• v.7 no.1
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• pp.29-41
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• 2006

The Imha watershed is vulnerable to severe erosion due to the topographical characteristics such as mountainous steep slopes. Sediment inflow from upland area has also deteriorated the water quality and caused negative effects on the aquatic ecosystem of the Imha reservoir. The Imha reservoir was affected by sediment-laden density currents during the typhoon 'Maemi' in 2003. The RUSLE model was combined with GIS techniques to analyze the mean annual erosion losses and the soil losses caused by typhoon 'Maemi'. The model is used to evaluate the spatial distribution of soil loss rates under different land uses. The mean annual soil loss rate and soil losses caused by typhoon 'Maemi' were predicted as 3,450 tons/km2/year and 2,920 ton/km2/'Maemi', respectively. The sediment delivery ratio was determined to be about 25% from the mean annual soil loss rate and the surveyed sediment deposits in the Imha reservoir in 1997. The trap efficiency of the Imha reservoir was calculated using the methods of Julien, Brown, Brune, and Churchill and ranges from 96% to 99%.

• Journal of the Korean Institute of Plant Engineering
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• v.23 no.4
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• pp.29-38
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• 2018

Through process quality information, the time required for process quality analysis has been drastically shortened, the process defect rate has been reduced, and the manufacturing lead time has been shortened and the on-time delivery rate has been improved. Therefore, The purpose of this study is to develop a quality information analysis system model that effectively shortens the time required for process quality analysis in automobile safety belt parts manufacturing process. As a result of experiments on communication operation between manufacturing execution system (MES) quality server, injection machine control computer, injection machine programmable logic controller (PLC) and terminal, in analyzing quality information, the conventional handwriting input method took an average of 20 minutes, but the new multi-network method took about 2 minutes on average. In addition, the process defect rate was reduced by 13% and the manufacturing lead time was shortened from 28 hours to 20 hours. The delivery compliance rate improved from 96 to 99%.

• Journal of Distribution Science
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• v.15 no.6
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• pp.37-46
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• 2017

Purpose - The paper aims to propose an optimization model for supporting the buyer-seller negotiations. We consider the price, quality, and delivery as evaluation criteria, also recognized as objectives for negotiation. Research design, data, and methodology - The methodology used in this paper involves the input-oriented DEA with the inverse optimization. Under the existence of several potential suppliers, the price would be considered to be the decision variable to conclude the negotiation so as to meet the desired level of the quality and delivery. The data set for six suppliers with three criteria is examined by the proposed approach. Results - We present the decision aid model by displaying the price spectrum as the changes of desired output levels. It overcomes the shortcomings from previous researches mainly based on the discrete types of scenario generations. This approach shows that the obtained results help the buyer understand the trade-offs between price and performance when he/she considers the negotiation. Conclusions - The paper contributes to the numerical models for buyer-supplier negotiation in that the model for the supplier evaluation and selection is closely linked with the model for negotiation. In addition, it eliminates the unrealistic negotiation strategy, and provides the negotiation strategies that the buyer would not shift the burden on suppliers by maintaining the current efficiency.

• The Journal of Information Systems
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• v.33 no.1
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• pp.133-157
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• 2024

Purpose The purpose of this study is to identify the utility and sacrifice factors of paid membership in domestic e-commerce based on the value-based acceptance model, and to determine its impact on perceived value and intention to continue using e-commerce. Design/methodology/approach This study confirmed the perceived benefits and sacrifice factors of e-commerce paid membership through in-depth interviews, and verified the research model through an online survey. Findings The study identifies seven perceived benefit factors(differentiation, enjoyment, sharing, point benefit, discount benefit, contents benefit, and delivery benefit) and three perceived sacrifice factors(fee, opportunity loss, complexity). Structural model verification reveals that discount benefit, delivery benefit, and opportunity loss significantly impact the perceived value in Coupang Rocket Wow, while discount benefit, point benefit, and fee significantly influence the perceived value in Naver Plus membership. The perceived value of both memberships positively influences the intention to continue using the respective e-commerce platforms. A comparison highlights a significant difference in the impact of opportunity loss on perceived value between Coupang Rocket Wow and Naver Plus memberships.

• Korean Journal of Social Welfare Studies
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• no.39
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• pp.221-252
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• 2008

The current social service delivery system for people with disabilities has four critical problems: absence of needs assessment, absence of case management, shortage of professional workers, and absence of local social welfare agencies. The Ministry of Health, Welfare, and Family of Korea has pushed forward with a project to reform the welfare infra-structure for people with disabilities since 2007. It's main purpose is to reorganize the social service delivery system for people with disabilities. A report from the project makes two suggestions: introduction of new standards for disability and set-up of disability service determination centers. The new standards for disability are suggested to include a work ability test and a welfare needs assessment tool as well as a medical standard. Three models for disability service determination centers are suggested: independent model, local governmental model, and public corporational model. Tentative operations using the three models are on the way in the second half of 2008. In order to reform the social service delivery system for people with disabilities, this study makes a fundamental suggestion: set-up of about 120 local welfare agencies over which the Ministry of Health, Welfare, and Family can have direct control, and which are equipped with professional workers who are able to perform needs assessment and case management. In actuality, welfare centers for disabled people are the best options for local welfare agencies for disabled people.

• Journal of Digital Convergence
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• v.19 no.5
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• pp.135-144
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• 2021

In Korea, the parcel delivery service is showing a high growth rate every year thanks to the activation of e-commerce, but the courier unit price continues to drop. Due to the low cost of parcel delivery, there is a need for improvement to normalize courier rates due to deterioration in profitability for couriers, deterioration in service for consumers, and overwork and accidents for workers. In this study, a rational rate system model and a systematic approach were presented. The study method modeled the chargeable weight by reflecting the voulumatirc weight and revenue ton by the volume and weight of the cargo, and presented a new parcel freight charge model based on the cost of delivery. In addition, a rate-determining support system was developed that can be easily, conveniently and reasonably determined on-site. In the demonstration, the rate difference was determined by relying on weight rather than volume, and 63.5% for personal courier and 40% for B2C courier were found to be inadequate. This study could be used as an alternative to solving side effects and problems at the delivery site, in the urgent need for research on ways to improve delivery prices.

• Journal of Pharmaceutical Investigation
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• v.29 no.2
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• pp.87-92
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• 1999

Drug delivery to the brain may be achieved by producing chimeric peptide, attaching the drug to protein 'vectors' which are transported into the brain from the blood by a receptor-mediated transcytosis through the blood-brain barrier (BBB). Since the BBB expresses high concentrations of transferrin receptor, and it was reported that anti-transferrin receptor mouse monoclonal antibody (OX26) undergoes transcytosis through the BBB, it is logical to assume that a drug delivery system via transferrin receptor-mediated transcytosis is a promising strategy. In the present study, therefore, we tested feasibility of several OX26 based vectors for the brain delivery of a model drug. Avidin-based delivery vectors such as OX26-streptavidin (OX26-SA), OX26-neutralite avidin (OX26-NLA) were chemically synthesized vectors and OX26 immunoglobulin G 3 type $C_{H}3$ fusion avidin $(OX26\;IgG3C_H3-AV)$ was genetically engineered. To improve the efficiency of producing chimeric peptide, we used avidin-biotin technology. Pharmacokinetics of $[^3H]biotin$ bound to OX26-SA, OX26-NLA and $OX26\;IgG3C_H3-AV$ was determined by intravenous injection technique, and their stabilities in plasma were analyzed using HPLC. The brain delivery of $[^3H]biotin$ bound to OX26-SA, OX26-NLA and OX26\;$IgG3C_{H}3-AV$ (expressed as %ID/g brain) was $0.22{\pm}0.01$, $0.18{\pm}0.01$ and $0.25{\pm}0.09$, respectively. The areas under the plasma concentration versus time curve (AUC) for OX26-SA, OX26-NLA, $OX26\;IgG3C_H3-AV$ from time zero to 60 min were $209{\pm}10$, $195{\pm}9$, $134{\pm}29\;%ID\;min/ml$ respectively and their total clearances $(CL_{tot})$ were $1.00{\pm}0.09$, $1.08{\pm}0.07$ and $1.54{\pm}0.29\;ml/min/kg$, espectively. These results showed that these vectors possess preferable pharmaceutical (e.g., resonable stability) and pharmacokinetics (e.g., significant brain uptake and enhanced AUC) for brain delivery. Therefore, these vectors may be broadly useful in the brain delivery of drugs that are not transported into the brain to a significant extent.

• Korean Journal of Construction Engineering and Management
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• v.12 no.5
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• pp.81-92
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• 2011

Recently, the MLTM (Ministry of Land, Transport and Maritime Affairs) has announced CM business guidelines, because it is expected that the CM deliveries are going to be increased for a civil engineering industry with enforcement of the CM at Risk. In this trend, The CM business guideline, which is currently announced, is for the steps after the CM contract. However, the practical business guideline from a planning phase for the CM delivery to a selection phase of a CMr (Construction Manager) is essential for public construction projects including the civil engineering projects that the frequency of the CM deliveries is not sufficient. Therefore, this study established a standardized process model from the planning phase for the CM delivery to the selection phase of the CMr. study configured a business breakdown structure for CM delivery. A prototype system for supporting the CM delivery was also developed, and a practical operability was verified by a case evaluation based on the developed system. Hence, it is expected that this study will be utilized as a supporting system of the CM delivery business for public clients, which have not sufficient cases of the CM delivery.

• Journal of Ginseng Research
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• v.39 no.2
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• pp.116-124
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• 2015

Background: Ginseng, the root of Panax ginseng (PG), is used widely as a herbal medicine to prevent and treat various diseases. Panax ginseng has pharmacological effects on neurodegenerative diseases such as Alzheimer's disease (AD). The present study evaluated the neuroprotective effects of PG and its possible neuroprotective mechanisms in advanced glycation end product (AGE)-induced AD in a rat model. Methods: Advanced glycation end products were injected bilaterally into the CA3 region of the rats' brains. The Morris water maze test and step-down type passive avoidance test were performed to evaluate their memory and cognitive abilities. The oxidation indexes in the hippocampus were detected. Immunohistochemistry was conducted to visualize the receptors for advanced glycation end products (RAGEs) and nuclear factor-kappa-light-chain-enhancer of activated B cell (NF-${\kappa}B$). Results: Behavioral results showed that PG (1 g/kg, 0.5 g/kg, and 0.25 g/kg) significantly shortened the escape latency, remarkably increased the number of crossing times, significantly decreased the number of errors, and prolonged the latency in rats with AGE-induced AD. Panax ginseng also significantly reduced the malondialdehyde level, increased the glutathione content, and increased superoxide dismutase activity in the hippocampus. Panax ginseng significantly decreased the expression of RAGE and NF-${\kappa}B$. The blockade of anti-RAGE antibody could significantly reduce AGE-induced impairments and regulate these expressions. Conclusion: Our results demonstrated that PG significantly inhibits AGE-induced memory impairment and attenuates Alzheimer-like pathophysiological changes. These neuroprotective effects of PG may be associated with the RAGE/NF-${\kappa}B$ pathway. Our results provided the experimental basis for applying PG in preventing and treating AD.

• Journal of Biosystems Engineering
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• v.16 no.2
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• pp.159-166
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• 1991

A simulation model was developed for analyzing a crop transport system using SLAMSYSTEM. The developed model could predict total delivered amount and delivery rate of a crop under various conditions of transport and analyze the effects of work factors on the efficiency of the crop transport system. A simulation model was also developed to analyze a rice transport system based on the generalized model of the crop transport system.