• Science of Emotion and Sensibility
• /
• v.25 no.4
• /
• pp.107-118
• /
• 2022

Human can rapidly detect and deal with dangerous elements in their environment, and they generally manifest as attentional bias toward threat. Past studies have reported that this attentional bias is affected by anxiety level. Other studies, however, have argued that children and adolescents show attentional bias to threatening stimuli, regardless of their anxiety levels. Few studies directly have compared the two age groups in terms of attentional bias to threat, and furthermore, most previous studies have focused on attentional capture and the early stages of attention, without investigating further attentional holding by the stimuli. In this study, we investigated both attentional bias patterns (attentional capture and holding) with respect to negative emotional stimulus in neurotypical adults and adolescents. The effects of anxiety level on attentional bias were also examined. The results obtained for adult participants showed that abrupt onset of a distractor delayed attentional capture to the target, regardless of distractor type (angry or neutral faces), while it had no effect on attention holding. In adolescents, on the other hand, only the angry face distractor resulted in longer reaction time for detecting a target. Regarding anxiety, state anxiety revealed a significant positive correlation with attentional capture to a face distractor in adult participants but not in adolescents. Overall, this is the first study to investigate developmental tendencies of attentional bias to negative facial emotion in both adults and adolescents, providing novel evidence on attentional bias to threats at different ages. Our results can be applied to understanding the attentional mechanisms in people with emotion-related developmental disorders, as well as typical development.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.46 no.4
• /
• pp.32-38
• /
• 2023

This study investigates the influence of particulate matter concentrations on the incidence of asthma, focusing on the delayed onset of symptoms and subsequent medical consultations. Analysis incorporates a four-day lag from the initiation of fine dust exposure and compares asthma patterns before and after the World Health Organization's (WHO) classification of fine dust as a Group 1 carcinogen in November 2013. Utilizing daily PM10 data and asthma-related medical visit counts in Seoul from 2008 to 2016, the study additionally incorporates Google search frequencies and newspaper article counts on fine dust to assess public awareness. Results reveal a surge in search frequencies and article publications after WHO announcement, indicating heightened public interest. To standardize the long-term asthma occurrence trend, the daily asthma patient numbers are ratio-adjusted based on annual averages. The analysis uncovers an increase in asthma medical visits 2 to 3 days after fine dust events. Additionally, greater public awareness of fine dust hazards correlates with a significant reduction in asthma occurrence after such events, even within 'normal' fine dust concentrations. Notably, behavioral changes, like limiting outdoor activities, contribute to this decrease. This study highlights the importance of analyzing accumulated medical data over an extended period to identify general public behavioral patterns, deviating from conventional survey methods in social sciences. Future research aims to extend data collection beyond 2016, exploring recent trends and considering the potential impact of decreased fine dust awareness amid the COVID-19 pandemic.

• The Plant Pathology Journal
• /
• v.40 no.1
• /
• pp.59-72
• /
• 2024

A comprehensive survey of mungbean-growing areas was conducted to observe leaf spot disease caused by Alternaria alternata. Alternaria leaf spot symptoms were observed on the leaves. Diversity of 50 genotypes of mungbean was assessed against A. alternata and data on pathological traits was subjected to cluster analysis. The results showed that genotypes of mungbean were grouped into four clusters based on resistance parameters under the influence of disease. The principal component biplot demonstrated that all the disease-related parameters (% disease incidence, % disease intensity, lesion area, and % of infection) were strongly correlated with each other. Alt a 1 gene that is precisely found in Alternaria species and is responsible for virulence and pathogenicity. Alt a 1 gene was amplified using gene specific primers. The isolated pathogen produced similar symptoms when inoculated on mungbean and tobacco. The sequence analysis of the internal transcribed spacer (ITS) region, a 600 bp fragment amplified using specific primers, ITS1 and ITS2 showed 100% identity with A. alternata. Potato virus X (PVX) -based silencing vector expressing Alt a 1 gene was constructed to control this pathogen through RNA interference in tobacco. Out of 50 inoculated plants, 9 showed delayed onset of disease. Furthermore, to confirm our findings at molecular level semi-quantitative reverse transcriptase polymerase chain reaction was used. Both phenotypic and molecular investigation indicated that RNAi induced through the VIGS vector was efficacious in resisting the pathogen in the model host, Tobacco (Nicotiana tabacum). To the best of our knowledge, this study has been reported for the first time.

• Korean Journal of Radiology
• /
• v.24 no.8
• /
• pp.784-794
• /
• 2023

Objective: To determine whether dynamic susceptibility contrast-enhanced (DSC) perfusion magnetic resonance imaging (MRI) can be used to evaluate posterior cerebral circulation in pediatric patients with moyamoya disease (MMD) who underwent anterior revascularization. Materials and Methods: This study retrospectively included 73 patients with MMD who underwent DSC perfusion MRI (age, 12.2 ± 6.1 years) between January 2016 and December 2020, owing to recent-onset clinical symptoms during the follow-up period after completion of anterior revascularization. DSC perfusion images were analyzed using a dedicated software package (NordicICE; Nordic NeuroLab) for the middle cerebral artery (MCA), posterior cerebral artery (PCA), and posterior border zone between the two regions (PCA-MCA). Patients were divided into two groups; the PCA stenosis group included 30 patients with newly confirmed PCA involvement, while the no PCA stenosis group included 43 patients without PCA involvement. The relationship between DSC perfusion parameters and PCA stenosis, as well as the performance of the parameters in discriminating between groups, were analyzed. Results: In the PCA stenosis group, the mean follow-up duration was 5.3 years after anterior revascularization, and visual disturbances were a common symptom. Normalized cerebral blood volume was increased, and both the normalized time-topeak (nTTP) and mean transit time values were significantly delayed in the PCA stenosis group compared with those in the no PCA stenosis group in the PCA and PCA-MCA border zones. TTP_PCA (odds ratio [OR] = 6.745; 95% confidence interval [CI] = 2.665-17.074; P < 0.001) and CBV_PCA-MCA (OR = 1.567; 95% CI = 1.021-2.406; P = 0.040) were independently associated with PCA stenosis. TTP_PCA showed the highest receiver operating characteristic curve area in discriminating for PCA stenosis (0.895; 95% CI = 0.803-0.986). Conclusion: nTTP can be used to effectively diagnose PCA stenosis. Therefore, DSC perfusion MRI may be a valuable tool for monitoring PCA stenosis in patients with MMD.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.22 no.3
• /
• pp.182-191
• /
• 2011

Objectives: The aim of this study was to investigate the sleep patterns of South Korean elementary school children and whether the differences in sleep patterns were related to behavior, emotional problems, attention and academic performance. Method: This study included a community sample of 268 boys and girls from fourth-, fifth- and sixth-grade classes in a South Korean metropolitan city from November to December 2010. The primary caregivers completed a questionnaire that included information on demographic characteristics, as well as the Child's Sleep Habit Questionnaire (CSHQ), the Korean version of Child Behavior Checklist (K-CBCL), the Korean version of the Learning Disability Evaluation Scale (K-LDES), the Korean version of ADHD Rating Scale (K-ARS) and the Disruptive Behavior Disorder Scale (DBDS). We conducted analyses on the CSHQ individual items, between the subscales, on the total scores and on the K-CBCL, the K-LEDS, the K-ARS and the DBDS. Results: Based on the findings from the CHSQ, the subjects had significantly higher scores for bedtime resistance ($9.18{\pm}2.17$), delayed sleep onset ($1.32{\pm}0.62$), the sleep duration ($4.19{\pm}1.52$) and daytime sleepiness ($14.10{\pm}3.55$) than the scores from the previous reports on children from western countries. The total CHSQ score showed positive correlations to all subscales of the K-CBCL : withdrawn (r=0.24, p<.005), somatic complaint (r=0.24, p<.005) and anxious/depressive (r=0.38, p<.005). Bedtime resistance was associated with oppositional defiant disorder (r=0.15, p<.05) and a positive correlation was demonstrated between sleep anxiety and the oppositional defiant disorder score (r=0.13, p<.05), night waking and the conduct disorder score (r=0.16, p<.05). Delayed sleep onset was related with low performance on the K-LDES with respect to thinking (r=-0.17, p<.05) and mathematical calculation (r=-0.17, p<.05). Conclusion: The results of this study reconfirm Korean children's problematic sleep patterns. Taken together the results provide that the reduced sleep duration and disruption of sleep pattern can have a significant impact on emotion, behavior, performance of learning in children. Further studies concerning more diverse psychosocial factors affecting sleep pattern will be helpful to understanding of the sleep health in Korean children.

• Clinical and Experimental Pediatrics
• /
• v.48 no.5
• /
• pp.488-494
• /
• 2005

Purpose : To outline the aspects of extubation by birth weight and find the predictors for success/failure at the first extubation in extremely low birth weight infants. Methods : One hundred thirteen extremely low birth weight infants(<1,000 g) who were admitted to NICU at Samsung Seoul Hospital between Jan. 2000 and Jun. 2004 were enrolled. Clinical characteristics that are thought to be related with extubation success or failure were compared with the success and the failure of the first extubation. Results : As the birth weight decreased, extubation success day was significantly delayed : $16{\pm}3day(d)$ in 900-999 g; $20{\pm}3d$ in 800-899 g; $35{\pm}4d$ in 700-799 g; $37{\pm}9d$ in 600-699 g; $49{\pm}12d$ in ${\leq}599g$. 25 out of 113 infants(22%) failed the first extubation. Preterm premature rupture of membrane was associated with extubation success, and air leak was associated with extubation failure, with a borderline significance. Postnatal and corrected age and body weight at the first extubation, nutritional status, and ventilator settings were not associated with extubation success or failure. Extubation success day was significantly delayed, and the incidence of late-onset sepsis and mortality was significant higher in the failure of the first extubation. Conclusion : We could not find significant predictors for success/failure at the first extubation. The failure of the first extubation had an increased risk of late-onset sepsis and death. Further studies are needed to find the predictors for extubation success/failure.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.15 no.3
• /
• pp.645-653
• /
• 2011

The aim of this study was to develop a Pulsed Magnetic Fields(PMFs) system which can produce effects locally and simulate muscular tissues equally. To evaluate the PMFs system we caused DOMS(Delayed Onset Muscle Soreness) to subjects in biceps of the arm. Then, we stimulated acupoint HT2 using PMFs(20 minutes) and TEAS(20 minutes) for 2 days. The other subjects did not stimulate. Then we checked body surface temperature in biceps of the arm. All subjects had an asymmetrical body surface temperature in biceps after exercise(Non-stimulation group=$2.00{\pm}1.16^{\circ}C$, TEAS group=$1.73{\pm}0.52^{\circ}C$, PMFs group=$1.48{\pm}0.51^{\circ}C$). After 1st stimulation all subjects had decreased temperature differences(Non-stimulation group=$1.37{\pm}0.71^{\circ}C$, TEAS group=$1.08{\pm}0.43^{\circ}C$, PMFs group=$1.23{\pm}0.15^{\circ}C$). PMFs group had a symmetry body surface temperature after 24 hours($0.05{\pm}0.06^{\circ}C$) and TEAS group had that after 48 hours($0.1{\pm}0.08^{\circ}C$). Non-stimulation group did not recovery after 48 hours($0.37{\pm}0.06^{\circ}C$). Therefore, PMFs on acupoint had an therapeutic effect in DOMS.

• The Korean Journal of Ecology
• /
• v.16 no.2
• /
• pp.135-149
• /
• 1993

In order to study and ecotypic variation of Phragmites communis Trin., we investigated germination rates, velocities, and protein band patte군 of seeds of three population of salt marsh, estuary and fresh water areas of Muan Peninsular in southwestern coast of Korea from March, 1990 to October, 1992. The highest germination rates of seeds were observed at $25^{\circ}C$; those of population of the estuary and fresh water are were 100% and that of the salt marsh was 95%. Similar germination rates were observed from the populations of estuary and fresh water areas at $30^{\circ}C$ and $20^{\circ}C$, but they decreased at $15^{\circ}C$. The onset of germination of seeds of three population was earlier $^{\circ}C$, but they decreased at $15^{\circ}C$. The onset of germination of seeds of th three populations was earlier at both $25^{\circ}C$, which was higher than those of any other areas, while that of fresh water areas was the lowest. were different; those of salt marsh and estuary decreased to 30% and 2.5%, respectively, at 3.0% of salt content, but seeds of the fresh water area did not germinate at all at the same salt content. The onset of germination was delayed in the order of the salt marsh, esturay and fresh water areas as salt content of culture solution increased. Germination of seeds from the population of salt marsh was found to begin earliest. The highest germination velocity of three populations was observed in the culture containing no salt. The germination velocity constant decreased as salt content of culture solution increased from 0.5% to 3.0%: those of the populations of the salt marsh, estuary, and fresh water areas were 9.50, 0.75 and 0.00, respectively, at the salt concentration of 3.0%. Soluble protein patterns of seedings from the three populations were analyzed by SDS-PAGE method. The results showed that protein patterns of the three populations were distinctly different qualitatively and quantitatively. The present study suggests that populations of Phragmites communis Trin. in the coast of Korea had taken ecotypic variations of habitats, i.e., fresh water, estuary, and salt marsh types, according to the salt content.

• Korean Journal of Materials Research
• /
• v.11 no.8
• /
• pp.629-635
• /
• 2001

To improve the ductility of $A1_3Hf$ intermetallics, which are the potential high temperature structural materials, the mechanical alloying behavior. the effect of Cu addition on the $Ll_2$ phase formation and the behavior of vacuum hot-pressed consolidation were investigated. During the mechanical alloying by SPEX mill, the $Ll_2 A1_3Hf$ intermetallics with the grain size of 7~8nm was formed after 6 hours of milling in Al-25at.%Hf system. The $Ll_2$ Phase of Al_3Hf$ intermetallics with the addition of 12.5at.%Cu, similar to that of the binary Al-25at.% Hf, was formed, but the milling time necessary for the formationof the $Ll_2$ phase was delayed form 6 hours to 10 hours. The lattice parameter of ternary $Ll_2(Al+Cu)_3Hf$ intermetallics decreased with the increase of Cu content. The onset temperature of $Ll_2$ to $D0_{23}$ phase in $Al_3Hf$ intermetallics was around 38$0^{\circ}C$, the temperature upon completion varied from 48$0^{\circ}C$ to 5$50^{\circ}C$ as the annealing time. The onset temperature of $Ll_2$ to $D0_{23}$ phase transformation in $(Al+ Cu)_3Hf$ intermetallics increased with the amount of Cu and the highest onset temperature of $700^{\circ}C$ was achieved by the Cu addition of 10at.%. The relative density increased from 89% to 90% with the Cu addition of 10at.% in $Al_3Hf$ intermetallics hot-pressed in vacuum under 750MPa at 40$0^{\circ}C$ for 3 hours. The relative density of 92.5% was achieved without the phase transformation and the grain growth as the consolidation temperature increased from 40$0^{\circ}C$ to 50$0^{\circ}C$ in $(Al+Cu)_3Hf$ intermetallics hot-pressed in vacuum under 750MPa for 3 hours.

• Childhood Kidney Diseases
• /
• v.9 no.1
• /
• pp.56-63
• /
• 2005

Purpose : Development of renal scarring is associated with delayed diagnosis and treatment of urinary tract infection(UTI). This study was performed to clarify how soon treatment should be started to Inhibit renal scarring after onset of UTI and the factors associated with renal scarring in children with a first episode of febrile UTI. Methods : We retrospectively reviewed 163 patients with a first episode of febrile UTI under the age of 2 years from April 2000 to Ap,il 2004. All patients had a DMSA renal scan and voiding cystourethrogram done in the diagnostic period, 6 months after which a follow-up renal scan was done. After patients wet-e divided into 2 groups according to the duration of fever prior to start of treatment, the duration of fever after start of treatment, and total duration of fever, initial and follow-up DMSA scan findings were analyzed among the different groups. We compared the factors associated with renal scars between the groups with and without renal scars. Results : The initial DMSA renal scan identified abnormal finding in 23% of the patients who were treated $\leq$24 hr from the onset of disease and in 43% of those with fever more than 24 hr. Renal scars developed in 33% of patients who were treated $\leq$24 hr and 38% of those with fever >24 hr prior to treatment. Renal scars developed in 34% of patients with remission of fever $\leq$48 hr after treatment and ill 50% of those with fever >48 hr after treatment. The risk for renal scars was significantly higher in children who had total duration of feyer >72 hr(67%) than in those with shorter duration(19%). In children with renal scars, VUR was most highly associated with an increased risk of renal scar formation. Conclusion : Although children with a first episode of febrile UTI are treated within 24 hr after onset of the fever, renal damage cannot be prevented completely and it is mainly associated with VUR. (J Korean Soc Pediatr Nephrol 2005;9:56-63)