• 대한한의학회지
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• 제31권3호
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• pp.107-121
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• 2010

Objective: This study aimed to ascertain the curative effects of Gamisipjeon-tang (GST) used for wound healing on the skin regeneration of deep second degree burns in mice. Material & Methods: In vitro, the $I{\kappa}B$ kinase (IKK) mRNA expression, inducible nitric oxide synthase (iNOS) mRNA expression, and cyclooxygenase-2 (COX-2) mRNA expression in the GST concentration from 1 mg/$m{\ell}$ to 10 mg/$m{\ell}$ were measured. In vivo, the mice were divided into four groups : the normal group, the BE group (burn-elicited group, control group), the DC group (Duoderm CGF-treated group after burn elicitation), and the GST group (Gamisipjeon-tang treated group after burn elicitation). To determine the anti-inflammatory effects, nuclear factor (NF)-${\kappa}B$ p65, iNOS, COX-2 positive reaction were measured by immunohistochemistry. To estimate the skin regenerative effects, change of burn area, 5-bromo-2'-deoxyuridine (BrdU), and fibroblast growth factor (FGF) positive reaction were analyzed. Results: In vitro, the iNOS, IKK, COX-2 mRNA expression decreased according to the increase of GST concentration. The significant decrease of COX-2, iNOS, NF-${\kappa}B$ positive reaction were the highest in the GST group, followed by the DC group and the BE group (p<0.05). The diameter of burn area was significantly decreased in the GST group as compared to that in the DC and BE group (p<0.05). The BrdU and FGF positive reaction increased more significantly in the GST group than in the DC group, and more significantly in the DC group than in the BE group on the 3rd and 7th day after burn (p<0.05). FGF positive reaction increased in the BE and DC group, whereas it decreased significantly in the GST group on the 14th day (p<0.05). The BrdU positive reaction increased in the BE group, whereas it decreased significantly in the DC and GST group on the 14th day (p<0.05). Conclusions: This study shows that GST could decrease the inflammatory response and accelerate the skin regeneration as compared to the duoderm CGF in mice with deep second degree burns.

• 한국작물학회지
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• 제28권2호
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• pp.173-183
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• 1983

동일벼 품종이라도 이앙기가 다르면 생육소요일수가 현저히 다르나 생육기간을 Growing degree days(GDD)로 표시하면 같은 벼 품종일 때 이앙기에 관계없이 생육기간동안 일정한 GDD로 표시할 수 있는 가능성을 검토하기 위하여 재래종, 일본도입종, 국내육성품종 등 과거 우리나라에서 많이 재배되어 왔던 일반계 16품종과 통일계 14품종을 공시하여 5월 10일부터 6월 29일까지 10일 간격으로 6회에 걸쳐 이앙한 후 이앙에서 출수, 출수에서 성숙까지 소요일수, 적산온도, GDD를 비교하였다. 일반계 품종은 모두 이앙이 늦어질수록 이앙에서 출수까지 일수가 감소하였으나 통일계 품종은 이앙이 늦어질수록 출수소요일수가 계속 감소하거나 6월 9일이나 6월 19일까지는 감소하나 그 이후 이앙시에는 감소하지 않거나 오히려 출수소요일수가 증가하였으며 이앙기에 따른 출수소요일수의 변이가 컸다. 이앙에서 출수까지 기간을 적산온도나 GDD로 표시하면 이앙기간에 출수소요기간의 변이가 소요일수로 나타낸 것 보다 적었으며 GDD간에는 일 최고온도와 최저온도를 더하여 2로 나눈 후 $10^{\circ}C$를 뺀 값을 누적한 것이 가장 효과적이었다. 품종별로는 통일계가 일반계 품종보다, 또 일반계 중에서는 조생종이 중만생종보다 이앙기간 이앙에서 출수까지 GDD의 변이가 적어 GDD의 이용에 더 적합하였다. 출수에서 성숙까지 일수는 출수가 늦어질수록 길어졌으나 그 연장정도는 일반계가 통일계보다 길었고 이앙기간에 등숙일수의 변이가 컸다. 최고온도가 $30^{\circ}C$보다 높을 때는 그 넘는 만큼의 온도를 3$0^{\circ}C$에서 빼서 최고온도를 대치하여 계산한 GDD와 적산온도로 계산한 생육기간이 최고온도를 보정하지 않고 계산한 GDD보다 등숙기간 GDD의 변이가 적었다. 등숙기간을 GDD로 표시하면 일반품종은 출수기에 관계없이 일정한 값을 보였으나 통일계는 이앙이 늦어질수록 등숙에 소요되는 GDD가 감소하였는데 이것은 출수가 늦어지면 립중이 낮아지고 등숙일수가 크게 연장되지 않았기 때문이었다.

• 한국어병학회지
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• 제6권2호
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• pp.163-175
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• 1993

1. 과산화물가가 90.4mEq/kg인 산화사료를 180일간 투여하여 Ceroid증이 발생한 어류를 1991년 10월 1일부터 11월 4일까지 Ceroid증의 치료실험을 행하였다. 2. 치료하기 위하여 정상사료(POV : 15.5mEq/kg)에 glutathione을 첨가하지 않은 실험군, 10, 20, 30, 40mg/kg/day을 첨가한 실험군 그리고 산화사료(POV : 90.4mEq/kg)만 투여한 대조군에서의 성장을 비교한 결과 대조군 및 무첨가한 실험군에서는 거의 성장이 이루어지지 않았으며, glutathione을 첨가한 모든 실험군에 있어서는 실험군별 차이없이 비슷하게 나타났다. 3. 병리조직학적으로는 glutathione 10, 30mg/kg 첨가한 실험군에서는 투여 7일째부터 ceroid 침착량 및 손상된 조직의 회복상태를 나타나기 시작하여 투여 21일 이후부터는 거의 정상적인 조직상을 나타내었다. glutathione 10mg/kg과 30mg/kg 첨가한 실험군별 조직회복상태는 10mg/kg/day 첨가한 실험군 보다 30mg/kg/day 첨가한 실험군에서가 치료효과가 양호한 것으로 나타났다.

• 대한약침학회지
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• 제12권4호
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• pp.111-118
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• 2009

Objectives: Herniated Intervertebral Disk(HIVD) of L-spine is one of the most common diseases that cause back pain and radiating pain. The aim of this study is to find out if the acupuncture therapy combined with Soyeom Pharmacopuncture therapy can improve the symptoms of the patients suffering from the disease more effectively than the acupuncture only therapy. Methods: We separated 30 patients into two groups. Group A was treated with the acupuncture only therapy, and Group B was treated with Soyeom Pharmacopuncture therapy in addition to the acupuncture therapy. We have observed patients for 7 days. We checked the Visual Analog Scale(VAS) for 4 times and did Straight Leg Raising Test(SLRT) twice. Results: 1. For 7 days from the admission day, the VAS score has been decreased significantly in both Group A and Group B. 2. For 7 days from the admission day, the VAS score of Group B has been appeared signifi cantly lower than that of Group A, so that we can know that patients in Group B has more rapidly improved than patients in Group A 3. From the admission day to the 3rd hospital day, the improvement index of VAS scroe of Group B has appeared significantly higher than that of Group A, but after 5th hospital day, there was no significance between the improvement index of VAS score of Group A and that of Group B. 4. For 7 days from the admission day, the SLRT(degree) has been improved significantly in both Group A and B, but there was no significance between the SLRT(degree) of Group A and that of Group B. Conclusion: We can use Soyeom Pharmacopuncture therapy with acupuncture therapy to make the patients suffering from back pain and radiating pain improve more rapidly.

• 한국도로학회논문집
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• 제13권1호
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• pp.21-32
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• 2011

포장의 동결깊이는 30년간의 기온자료를 분석하여 만든 동결지수를 근거로 하여 동상방지층의 두께를 결정한다. 본 연구에서의 현장계측 지역은 동결지수에 따라 동결지수 550~650$^{\circ}C{\cdot}$일, 450~550$^{\circ}C{\cdot}$일, 350~450$^{\circ}C{\cdot}$일로 구분하여 지역을 선정하였고, 각 지역별로 절토부, 절성경계부, 저성토부(2m 이하 성토부) 구간으로 단면을 구분하였다. 각 단면에 동상방지층 유 무를 구분하여 포장층별로 계측기(온도, 함수비)를 설치하고 데이터를 수집하였다. 현장 모니터링 시스템을 통하여 수집된 데이터 분석을 통하여 포장된 도로의 동결깊이를 결정하는데 이용할 수 있다. 연구 결과, 동상방지층이 없을 경우 동결지수 550~650$^{\circ}C{\cdot}$일 지역에서는 대기온도에 따라 겨울철 노상층의 온도가 $0^{\circ}C$ 이하로 나타났고, 동결지수 450~550$^{\circ}C{\cdot}$일 지역에서는 지역별로 상이했으며, 동결지수 350~450$^{\circ}C{\cdot}$일 지역에서는 동상방지층이 없어도 노상층의 온도가 $0^{\circ}C$ 이하로 나타나지 않았다. 또한, 포장 단면별로 동결깊이를 비교한 결과 대기온도에 따라 동결깊이는 절토부가 가장 높았으며, 절성경계부, 저성토부 순으로 단면별 차이가 나타났다.

• Journal of Korean Biological Nursing Science
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• 제4권2호
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• pp.113-125
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• 2002

This study is to evaluate contamination of the 3-way stopcocks connected to infusion set, which is used to the patients admitted to emergency room in a general hospital in D city. The data were collected from Oct. 1, 2001 to Feb. 25, 2002. First of all, in order to select microorganisms, From the 50 patients were randomized, Coagulase Negative Staphylococcus, Staphylococcus aureus, micrococcus, Pseudomonas aeruginosa, Acinetobacter detected. Coagulase Negative Staphylococcus, Staphylococcus aureus, micrococcus were determined to be evaluated in this study. As a result, 8 of the patients were Coagulase Negative Staphylococcus positive(>15 colonies), 4 were Staphylococcus aureus positive(>15 colonies). 1 was micrococcus positive(>15 colonies). Among the patients who were Coagulase Negative Staphylococcus positive 112(average) colonies were detected on the first day, 429 were on the second day, and 563 were on the third day. In case of patients of Staphylococcus aureus positive, 85(average) colonies were detected on the first day, 151 were on the second day, and the 203 were on the third day. CNS was cultured using API kit for the 8 patients who were in CNS positive. One case was detected Staphylococcus capitis, another one case was Staphylococcus chromogenes. Two cases were Staphylococcus xylosus, another two were Staphylococcus hominis, and the remainer were Staphylococcus epidermidis. As a result, the API codes of two Staphylococcus epidermidis had shown the same pattern, and the resistance patterns of the them were the same, too. As a result of resistance test among 5 patients who have shown that the same resistance pattern in 02SAK1, 02SAK5, 02SAK2, 02SAK4. As a result of this study, aseptic technique of 3-way stopcock intravenous therapy can protect infections, and it is needed the sterilization of the 3-way stopcock just before injection using disinfectants. It needs to improve the 3 way stopcock change intervals from 48 hours.

• 한국버섯학회지
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• 제3권1호
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• pp.35-39
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• 2005

고활성칼슘은 패각류를 고온($1,500{\sim}5,000^{\circ}C$)에서 고전압(약 15,000V)의 전기를 통하여 전기분해해서 생산하는 산화칼슘이며, 제품의 순도가 대단히 높고 독성이 전무하며, 분자간의 결합력을 약화시켜 생체 내 활성도와 용해도가 탁월한 물질이다. 이의 버섯의 생육단계별 고활성칼슘 처리효과는 다음과 같다. 느타리버섯은 배지 수분조절시 혼합할 때 균사배양일수가 2일 단축, 초발이 소요일수는 1일 빠르고, 유효발이경수가 15개, 개체중이 148g/850cc로 6.5% 증수되었다. 큰느타리버섯은 배지 수분조절시 혼합할 때 균사배양일수가 3일 단축, 초발이 소요일수는 1일 빠르고, 생육소요일수가 6일간 단축, 개체중이 108.1g/850cc로 9.7% 증수되었다. 팽이버섯은 균긁기 시 처리가 가장 좋았다. 균사배양일수가 2일 단축, 초발이 소요일수는 3일 빠르고, 생육기간은 1일 빠르며, 재배기간은 3일간 단축, 개체중이 165g/850cc로 6.7% 증수되었다. 표고는 배지 혼합시 배양일수가 3일, 갈변화 시작일이 2일, 첫수확 소요일수가 4일 단축되며, 수량은 169g/2kg으로 9.7% 증수되었다.

• 근관절건강학회지
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• 제19권2호
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• pp.184-196
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• 2012

Purpose: This study aimed to investigate the degree of discomfort and to identify factors related with discomfort in patients wearing thigh-length compression stockings after orthopedic surgery. Methods: The participants were 105 patients wearing thigh-length compression stockings after orthopedic surgery at two hospitals in B city. Data were collected by the scale of discomfort in wearing compression stockings from July 5 to October 20, 2011. Results: Mean score of discomfort on wearing compression stockings was significantly higher at post-op. day 3 than day 1 (t=-2.30, p=.004). Discomfort scores for 'itching skin' and 'tightened leg' items were higher than others. There was significant difference in discomfort at post-op. day 1 according to surgical regions. The total score of discomfort at post-op. day 3 was positively related with the body mass index (r=.20, p=.041). Conclusion: Wearing thigh-length compression stockings to prevent deep vein thrombosis may cause physical and psychological discomfort for orthopedic surgical patients. To reduce discomfort in wearing compression stockings, nurses need to intervene discomfort and problems related to the stockings post-operatively.

• 대한소아치과학회지
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• 제10권1호
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• pp.47-55
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• 1983

The authur surveyed the caries experience of 108 preschool children and collected their five-day dietary data, and evaluated the cariogenicity applied to their diets and discussed the relationship between their caries experience and their diet. The results were as follows: 1. As a frequency of consumption of cariogenic foods by degree of retentiveness, highly retentive foods like sugars and dried fruits had been taken once every 3 days, next highly retentive foods like confections and breads had been taken once everyday, slightly retentive foods like ice-creams and fermented milk also had been taken once everyday, and low retentive foods like soft drinks had been taken once every 6 days. 2. The highest caries experienced children ingested more frequently retentive foods like ice-creams, fermented milk and sugars than the lowest caries experienced children. 3. As a potential cariogenicity, the mean number of cariogenic ingestions in a day was 2.26, the mean retentiveness in a day was 5.93, and the mean cariogenicity score per ingestion in a day was 2.51. 4. The highest caries experienced children had higher values in the mean cariogenic ingestions, the mean retentiveness, and the mean cariogenicity score than the lowest caries experienced children.

• Journal of Nutrition and Health
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• 제31권2호
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• pp.220-230
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• 1998

The purpose of this study was to develop and validate the Food frequency questionnaire (FFQ) for dietary studies of Koreans. One hundred and five food items for the Food frequency questionnaire were selected based on information of frequently consumed foods from National Nutrition Survey Reports and on raw data from a dietary survey on diabetic patients. Frequency of consumption was determined through nine categories ranging from more than three times a day to almost never to indicate how often the specified amount of each food item was consumed during the past month. Three portion sizes were given for each food item(small, medium or large) with respect to a stated medium portion. Seventy-three healthy women served for the validation study. They completed both the FFQ and a 3-day diet record. The FFQ estimate of mean nutrient intake was higher by 10-20% than that of the 3-days diet record and the Spearman correlation coefficients between the two methods ranged from 0.26 to 0.59 . The degree of agreement was from 36% to 38% when nutrients intake assessed by the FFQ and 3day diet record were classified within the same quintile. On the whole , the result of this study seemed to be in good agreement with other studies. Therefore the FFQ developed in this study is considered to be a reliable tool in assessing the dietary habits of Korean.