• Journal of Preventive Medicine and Public Health
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• v.39 no.5
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• pp.411-418
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• 2006

Objectives: The purpose of this study was to determine whether the disabled have worse access to primary care than the non-disabled. Methods: We used the National Disability Registry data and the National Health Insurance data for the calendar year 2003, and we analyzed 807,380 disabled persons who had been registered until December 2001 and we also analyzed 1,614,760 non-disabled persons for nine ambulatory care sensitive conditions (ACSCs). The rates of physician visits and hospitalizations for the patients with ACSCs were compared between the disabled and the nondisabled. Multiple logistic regression analysis was used to evaluate the association between medical care utilization and disability and to assess the association between hospitalization and the number of physician visits while controlling for potential confounders. Results: The numbers of physician visits per 100 patients were $0.78{\sim}0.97$ times lower for the disabled than that for the non-disabled with five of nine ACSCs. The numbers of hospitalizations per 100 patients were $1.16{\sim}1.77$ times higher for the disabled than that for the non-disabled with all the ACSCs. While the ORs of a physician visit for the disabled were significantly lower than that for the non-disabled with all the ACSCs (OR: $0.44{\sim}0.70$), and the ORs of hospitalization for the disabled were significantly higher (OR: $1.16{\sim}1.89$). The lower physician visit group (number of physician visits ${\leq}$1) was more likely to be hospitalized than the higher physician visit group (number of physician visits ${\geq}$2) (OR: $1.69{\sim}19.77$). The effect of the physician visit rate on hospitalization was larger than the effect of disability on hospitalization. Conclusions: The results suggest that the disabled were more likely to be hospitalized for ACSCs due to their lower access to primary care.

• The Journal of the Korea Contents Association
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• v.17 no.3
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• pp.444-453
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• 2017

Moral education is essential to the military in fostering elite warriors to have clear sense of their nation and the security, while arming themselves with military spirit that strives for victory. To reach this goal, various moral education has been set forth through boot camp training, academic education, unit training, etc. depending on various subject and supporting agencies in question. Also, in order to heighten the effect of the education, various attempts to combine concert-style cultural activities with the programs are carried out. However, the ultimate goal for this moral education is to facilitate soldiers to voluntarily set their minds and will in combat, and the current education system lacks that motivation as it concentrates mostly on educating knowledges about nationality and security. Under such circumstances, various units have attempted to raise morality in creating many public and media activities within the unit, which proven to be successful. In theory, the usual definitions in the field of education such as emotion, interest, attitude, and personality can be expanded upon with public and media activities. With this in mind, we have researched on how effective this method is by conducting various public and media activities in multiple units, total of 531 soldiers, starting from June to July of 2016. As a result, these activities brought positive effects on young soldiers to build pride in their assigned units, and also increased their willingness to carry out their assignments and missions. Through this research, we drew to the conclusion that unit-level public and media activities, which was solely used for gaining trust and communicate with the general civilians, can be used to boost the soldiers moral strength and help them express the strength in action.

• Journal of Applied Biological Chemistry
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• v.61 no.2
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• pp.109-117
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• 2018

Recently, cancer incidence in modern society is increasing sharply. DNA damage is caused by intrinsic or extrinsic factors in the human body, cells protect themselves by defense mechanism against DNA damage. Also, Aberrant DNA and deficient DNA repair are closely associated with various diseases, including aging and cancer. Researchers are interested in search for proper materials to inhibition for DNA damage. As knew the side effects of synthetic antioxidant, some researches have been conducted about cancer prevention materials derived from nature. Root of Smilax china, in Liliaceae, is used detoxification and tumor treatments traditionally. However, studies on the inhibitory effect of DNA damage haven't progressed. In this study, antioxidant activity and protective effects on oxidative DNA damage of S. china root were confirmed, relationship between those activities and contents of phenolic compounds in plants were established. S. china root effectively removed 1,1-diphenyl-2-picryl-hydrazyl radicals and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid radicals. The quantification and identification of phenolic compounds were confirmed by high performance liquid chromatography analysis, its antioxidant activity was associated with some phenolic compounds. In addition, protective effects against hydroxyl radicals and ferrous ion-induced oxidative DNA damage were confirmed in plasmid DNA. In the cellular levels, S. china root suppressed the expression of ${\gamma}$-H2AX and p53 protein in NIH 3T3. Besides, S. china root suppressed H2AX and p53 mRNA levels. In conclusion, S. china root had the effect on DNA protection and antioxidant.

• The Korean Journal of Pesticide Science
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• v.11 no.4
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• pp.222-229
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• 2007

It is well known the functional foods are very useful to prevent serious diseases and promote health. Therefore, they are often called as nutraceuticals, designer foods, and pharmafoods, etc. Most of foods have diverse functions because they provide nutrients, energies and fibrinoid materials. When foods are taken in the body, they promote the biological defense system against diseases through the supply of the essential or healthy materials to human being's organs. The mode of action and functional foods in human body have not been clarified yet. Antioxidant is known as one of the therapeutic aids which can be reduced pesticide poisoning. Onion has a strong antioxidant effect. This study was carried out to elucidate an antioxidant function of onion by determination of superoxide dismutase in liver, lung, serum of male rat administered by intraperitonial injection of 0, 2, $4\;mg\;kg^{-1}$ cblorpyrifos after administrated orally with onion for 6 weeks. Damage of liver and kidney was also investigated by biochemical analysis of serum(AST, ALT, BUN/Creatine ratio). SOD(superoxide dismutase) activity of onion-administrated group is higher than control group. In liver and lung, SOD activity of onion+cblorpyrifos administrated group is higher than only chlorpyrifos administrated group. BUN/Creatinine ratio of onion+chlorpyrifos administrated group was decreased compared with only chlorpyrifos-administrated group.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.32 no.1
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• pp.63-73
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• 2014

Recently, researches on DBRN(DataBase Referenced Navigation) system are being carried out to replace GNSS(Global Navigation Satellite System), as weaknesses of GNSS were found that are caused by the intentional interference and the jamming of the satellite signal. This paper describes the gravity gradient modeling and the construction of EKF(Extended Kalman Filter) based GGRN(Gravity Gradient Referenced Navigation). To analyze the performance of GGRN, fourteen flight trajectories were made for simulations over whole South Korea. During the simulations, we considered the errors in both DB(DataBase) and sensor as well as the flight altitudes. Accurate performances were found, when errors in the DB and the sensor are small and they located at lower altitude. For comparative evaluation, the traditional TRN(Terrain Referenced Navigation) was also developed and performances were analyzed relative to those from the GGRN. In fact, most of GGRN performed better in low altitude, but both of precise gravity gradient DB and gradiometer were required to obtain similar level of precisions at the high altitude. In the future, additional tests and evaluations on the GGRN need to be performed to investigate on more factors such as DB resolution, flight speed, and the update rate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.29-36
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• 2017

In this study, acombined cogeneration power plant produced two types of thermal energy and electric or mechanical power in a single process. The performance of each component of the gas turbine-combined cogeneration system was expressed as a function of the fuel consumption of the entire system, and the heat and electricity performance of each component. The entire system consisted of two gas turbines in the upper system, and two heat recovery steam generators (HRSG), a steam turbine, and two district heat exchangers in the lower system. In the gas turbine combined cogeneration system, the performance test after 10,000 hours of operation time, which is subject to an ASME PTC 46 performance test, was carried out by the installation of various experimental facilities. The performance of the overall output and power plant efficiency was also analyzed. Based on the performance test data, the test results were compared to confirm the change in performance. This study performed thermodynamic system analysis of gas turbines, heat recovery steam generators, and steam turbines to obtain the theoretical results. A comparison was made between the theoretical and actual values of the total heat generation value of the entire system and the heat released to the atmosphere, as well as the theoretical and actual efficiencies of the electrical output and thermal output. The test results for the performance characteristics of the gas turbine combined cogeneration power plant were compared with the thermodynamic efficiency characteristics and an error of 0.3% was found.

• Journal of Satellite, Information and Communications
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• v.3 no.1
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• pp.41-47
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• 2008

Line-of-sight communications cannot easily support korean armed forces because of mountainous terrain. ADD(Agency for Defense Development) introduced ANASIS(Army Navy Air-force Satellite Information System) to meet the Korean warfighter's operational needs. Currently, army's military satcom terminal is designed for either fixed site or on-the-pause operation. The US army is under development of multi-band integrated on-the-move satellite terminals to let the army's communication capability to keep pace with globally deployable Joint Task Force for network-centric application. In this paper we analyzed X-band and Ka-band link and subsystem requirement. Our focus here is to describe key technical issues. Especially, On the basis of 3dB beam width of 0.9m antenna, Tracking accuracy and disturbances compensation signal processing on-the-move of Antenna Tracking system is analyzed. Also, protocol is analyzed that minimize blockage on the move due to an obstacle. when the received signal blocked, it stop to transmit burst signal and retransmit when blockage removed through received synchronization signal monitoring. Analyzed specification will be used to make prototype terminal to analyze risk for mass production

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.417-428
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• 2020

Housekeeping genes are expressed in cells of all organisms and perform basic cellular functions such as energy generation, substance synthesis, cell death, and cell defense. Accordingly, the expression levels of housekeeping genes are relatively constant, and thus they are used as reference genes in gene expression studies, such as protein expression and mRNA expression analysis of target genes. However, the levels of expression of these genes may be different among various tissues or cells and may change under certain circumstances. Therefore, it is important to select the best reference gene for specific gene expression research by exploring the stability of housekeeping gene expression. This review summarizes housekeeping genes found in humans, chickens, pigs, and rats in the literature and estimates expression stability using geNorm, NormFinder, and BestKeeper software. The most suitable reference housekeeping gene can selected based on expression stability according to the experimental conditions of the gene expression study and can thus be applied to data normalization.

• Nutrition Research and Practice
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• v.14 no.4
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• pp.334-351
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• 2020

BACKGROUND/OBJECTIVES: This study was designed to investigate the improvement effect of white ginseng extract (GS-KG9) on D-galactosamine (Ga1N)-induced oxidative stress and liver injury. SUBJECTS/METHODS: Sixty Sprague-Dawley rats were divided into 6 groups. Rats were orally administrated with GS-KG9 (300, 500, or 700 mg/kg) or silymarin (25 mg/kg) for 2 weeks. The rats of the GS-KG9- and silymarin-treated groups and a control group were then intraperitoneally injected Ga1N at a concentration of 650 mg/kg for 4 days. To investigate the protective effect of GS-KG9 against GalN-induced liver injury, blood liver function indicators, anti-oxidative stress indicators, and histopathological features were analyzed. RESULTS: Serum biochemical analysis indicated that GS-KG9 ameliorated the elevation of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) in GalN-treated rats. The hepatoprotective effects of GS-KG9 involved enhancing components of the hepatic antioxidant defense system, including glutathione, glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT). In addition, GS-KG9 treatment inhibited reactive oxygen species (ROS) production induced by GalN treatment in hepatocytes and significantly increased the expression levels of nuclear factor erythroid-2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) proteins, which are antioxidant proteins. In particular, by histological analyses bases on hematoxylin and eosin, Masson's trichrome, α-smooth muscle actin, and transforming growth factor-β1 staining, we determined that the administration of 500 mg/kg GS-KG9 inhibited hepatic inflammation and fibrosis due to the excessive accumulation of collagen. CONCLUSIONS: These findings demonstrate that GS-KG9 improves GalN-induced liver inflammation, necrosis, and fibrosis by attenuating oxidative stress. Therefore, GS-KG9 may be considered a useful candidate in the development of a natural preventive agent against liver injury.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.692-699
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• 2017

The purpose of this study is to investigate the display fatigue quantitatively when operating 2D and HMD-based 3D VR bicycles. Though it is generally accepted that the display fatigue induced by 3D VR is greater than that induced by 2D VR, there have been few studies which attempted to measure the display fatigue scientifically. The subjective degree of cybersickness and quantitative flicker fusion frequency (FFF) were measured in twenty subjects (Male 10, Female 10) before and after they operated 2D and 3D VR bicycles for 5 min. Two dependent variables affected by the 2D and 3D VR displays were analyzed and compared statistically based on scientific evidence and research. This study showed that 3D VR resulted in a significantly higher cybersickness rate and a significant lower FFF rate than 2D VR. Given the current propensity to couple VR techniques with exercise equipment, it seems appropriate to verify the general beliefs through scientific methods and experimental measures such as the FFF and cybersickness questionnaires.