• 대한소아치과학회지
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• 제7권1호
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• pp.75-83
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• 1980

Rickets is not the deposite of minerals in the skeletal tissue and the retardation of skeletal growth in growing in growing animals. This study was undertaken to investigate the histologic effects of experimental rickets on the dental structure of the albino rats, and to show the relationship between the histological effects and the pulpal disease which induced premature loss of the primary teeth. This study was based on material obtained from 40 white rats that were placed on a rachitogenic diet for a period 1 to 56 days after weaning (at 24 days). In addition, a study was made of 25 litter mates, 24 to 80 days, that were fed a normal diet. The following results were obtained: 1. Enamel formation and calcification showed no significant changes and no hypoplasia. 2. Dentin formation and calcification was retarded and disturbed. In the experimental group, predentin/calcified dentin was remarkablly increased. 3. Newly formed dentin showed interglobular texture (less homogenous calcification) and the predentin was significantly wider and thicker, and there was an irregular wave in the basal portion of the rat's incisors. 4. In cementum, Matrix formed at almost a normal rate but calcification was defective. So cementoid tissue was increasesd. 5. The formation of the alveolar bone was at almost a normal rate but calcification was retarded. The trabecular bone was filled with osteoid tissue and thicker than in normal groups.

• 한국세라믹학회지
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• 제26권4호
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• pp.479-486
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• 1989

According to the phase diagram, 6Bi2O3.GeO2 composition melts congruently at 93$0^{\circ}C$ and forms a stable ${\gamma}$-6Bi2O3.GeO2 crystal phase below the melting point. But when the melt of this composition was cooled at a rate 1-15$0^{\circ}C$/min without tapping by a glass rod or impurity addition, a metastable $\delta$-6Bi2O3.GeO2 crystal phase was formed. It is due to that as the nucleation energy barrier of $\delta$-6Bi2O3.GeO2 crystals, which have more open and defective structure, is lower than that of ${\gamma}$-6Bi2O3.GeO2 crystals. When impurities or ${\gamma}$-6Bi2O3.GeO2 crystals existed in the melt, stable ${\gamma}$-6Bi2O3.GeO2 crystal phase was formed at various cooling rate. It is because of that the impurities or the ${\gamma}$-6Bi2O3.GeO2 crystals role as a seed crystal and as a result the nucleation energy barrier of ${\gamma}$-6Bi2O3.GeO2 crystals is lowered.

• 스마트미디어저널
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• 제11권9호
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• pp.47-55
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• 2022

스마트팩토리 제조공정에서의 품질관리는 중요한 요소이다. 현재, 금형 공정으로 생산되는 생활가전 제조부품의 품질검사는 대부분 작업자의 육안으로 진행되고 있으며 이로 인한 검사의 오류율이 높은 실정이다. 이러한 품질공전 개선을 위하여 결함 자동검출 시스템을 설계하여 구현하였다. 제안 시스템은 특정 위치에서 고성능 스캔 카메라로 대상물을 촬영하여 영상을 획득하고, 비전검사 알고리즘에 따라 긁힘, 찍힘, 이물질에 의한 불량품을 판독한다. 본 연구에서는 긁힘에 대한 불량 인식율을 높이기 위하여 깊이 정보 기반 분기 판단 알고리즘(Depth-based branch decision algorithm, DBD)을 개발하여 정확도를 높였다.

• 한국안전학회지
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• 제39권1호
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• pp.33-40
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• 2024

This study analyzes the impact of regular preventive maintenance (PM) on reducing the failure rate and occurrence of falling accidents of industrial overhead doors. A reliable safety device model with an additional safety device, which is installed to replace a defective one, is proposed. The research methodology involves collecting breakdown and falling accident records, comparing and analyzing data before and after regular PM implementation, and experimenting with two types of retrofittable safety devices. Key findings are as follows. 1. Regular PM implementation significantly reduces the failure rate of old overhead doors. 2. A parallel structured model with two alternative safety devices can minimize falling accident risks. The study's contributions include the following. 1. The positive impact of PM on extending overhead door lifespan is quantified. 2. A general safety device model that can be retrofitted and used as replacement with a fail-safe function is proposed.

• Journal of Biosystems Engineering
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• 제26권3호
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• pp.271-278
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• 2001

Many workers in the garlic peeling factory are separating the sound peeled garlics from the unpeeled and defective ones in a manual way. In order to reduce the seasonal labor requirement and operating cost, the mechanized garlic sorting system such as the vision-based garlic sorter should be developed. This study was conducted as one of basic studies on developing quality evaluation technique for peeled garlics, especially to developed the system for acquiring the whole surface images of garlics with a CCD camera. The following results were obtained from this study. 1. The belt-type garlic rotation system was devised to apply for the vision-based garlic sorter and was tested to decide the criteria of design and optimum conveying speed. 2. To evaluate the performance of the developed garlic rotation system, feeding rate and rotating rate were measured under the conditions of four experimental factors such as the inclined angle of rotating belt, the inclined angle of feeding belt, the height of plate arrays on feeding belt and the conveying speed of belts. And the capacity of the system according to mixture ratios of peeled garlics and unpeeled garlics was analyzed as a feasibility test. 3. For the inclined angle of rotating belt 20°and height of plate array on feeding belt 22㎜, the maximum rotating rate for garlic samples including unpeeled ones was 81.1% at the conveying speed of 4.2 garlic/sec. And under these condition, the maximum feeding rate was 85% at the inclined angle of feeding belt 6.5°. 4. The capacity of the developed garlic rotation system was almost constant regardless of mixture ratio of peeled garlics and unpeeled garlics and its range was 2.95∼3.92 garlic/sec. At the conveying speed of 4.2 garlic/sec, the capacity of the garlic rotation system was calculated ad 58∼64 kg/hr. 5. To improve performance of the garlic rotation system, it is recommended to develop a device to slide garlics into feeding belt.

• 전기전자학회논문지
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• 제26권2호
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• pp.219-225
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• 2022

우리나라의 섬유산업 중 염색가공 분야는 에너지 다소비 업종으로, 노동 집약적 특성에 따라 원단위 생산성이 낮고, 대부분 중소·영세기업 특징이 있다. 염색 원단의 불량률이 높아지면 재염색으로 인한 생산단가 상승과 초과 에너지 투입으로 비용이 증가하기 때문에, 불량률을 최소를 통한 생산량 향상이 초점이었다. 또한 고온고압의 환경에서 이루어지는 염색공정은 사고 위험으로 염색기 원단 투입구를 실시간으로 개방할 수 없기 때문에 실시간으로 원단의 염색상태 확인이 어려웠다. 최근에는 염액을 실시간으로 모니터링하는 연구가 활발히 진행중이다. 본 논문에서는 탁도, pH, 전도도 센서를 이용하여 염액의 흡진율을 계측할 수 있는 복합센서 흡진율 모델 및 구성시스템을 제안하였으며, 실험방법소개와 실험결과 분석을 실시하였다.

• 한국산학기술학회논문지
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• 제21권6호
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• pp.178-186
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• 2020

국내 무기체계 연구개발과정에서 소프트웨어 신뢰성이 중요한 요소로 여겨지고 있다. 그래서 무기체계 소프트웨어 연구개발 절차에는 소프트웨어 신뢰성 향상을 위한 활동들이 포함되어 있다. 하지만 개발절차에 포함된 활동은 소스 코드 정적 및 동적 분석으로 국제 표준에서 요구하는 활동과 다소 차이가 존재한다. 소프트웨어 신뢰성 관련 국제 표준인 IEEE std 1633-2016에서는 소프트웨어 신뢰성 확보를 위한 프로세스를 정의하고 있으며, 이들 가운데 소프트웨어 신뢰성 추정을 필수 활동이라고 이야기하고 있다. 소프트웨어 신뢰성 추정은 시험단계의 결함을 기반으로 통계 모델을 활용해 현재 시점의 소프트웨어 신뢰성을 추정하는 활동이다. 추정한 모델을 기반으로 소프트웨어 고장률을 추정할 수 있으며, 목표 고장률과의 비교를 통해 시험 종료 여부를 결정할 수 있다. 따라서 본 연구에서는 무기체계 소프트웨어 개발 과정에 소프트웨어 신뢰성 추정 모델을 적용하였다. 그 결과 목표한 소프트웨어 신뢰성을 달성하기 위해 지속적인 시험이 진행되었으며, 정량적인 소프트웨어의 신뢰성을 확인 할 수 있었다. 본 연구를 기반으로 무기체계 소프트웨어의 개발 과정에서 국제 표준에서 제시한 소프트웨어 신뢰성 공학 프로세스를 반영하는 노력이 지속적으로 이루어지기를 기대한다.

• 대한두경부종양학회지
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• 제19권1호
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• pp.25-33
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• 2003

Background and Objectives: The Herpes Simplex type 2 Defective Infectious Single Cycle virus (DISC virus) is attenuated virus originally produced as viral vaccines but are also efficient gene transfer vehicle. The main goals of this study were to examine the efficiencies of the gene transfer using DISC vectors for various head and neck squamous cell carcinoma cell lines and to evaluate the efficacy of vaccination with DISC virus carrying a immunomodulatory genes (GM-CSF) as cancer therapy in a organotopic oral cavity squamous cell cancer model. Materials and Methods : We determinated the gene transfer efficiency of DISC virus by x-gal stain method and proved gene and protein expression of DISC-GMCSF transfected SCCVII cells by RT-PCR and ELISA method. Also we evaluated the ex vivo vaccination effects of SCCVII/GMCSF (DISC-GMCSF transfected SCCVII vaccine) vaccine on preventing the recurrence of micro-residual tumor. After the vaccination of SCCVII/GMCSF, specific cytotoxic T-cell responses was evaluated by CTL assay. Results: At an MOI of 10 DISC virus showed 64-88% of transfection rates in various head and neck squamous cancer cell lines. SCCVII cells transduced by DISC virus vector (MOI=10) carrying the GM-CSF gene, produced 4.5 nanogram quantities of GM-CSF per $10^6$ cells. In vivo vaccination using tumor cells transduced ex vivo with DISC-GMCSF resulted in better protection rate against subsequent tumor recurrence in organotopic oral cavity cancer model. Although tumor free survival rate was not statistically significantly increased in vaccination group (p=0.078), tumor specific cytotocic T-cell responses were significantly increased in SCCVII/GMCSF vaccination group. Conclusion: These data demonstrate that; 1) The DISC virus vector is capable of efficient gene transfer to various head and neck squamous cancer cell lines, 2) GM-CSF secreting genetically modified tumor vaccine (SCCVII/GMCSF) efficiently protected against tumor recurrence in organotopic micro-residual oral cavity cancer model and produced tumor specific cytotoxic T-cell response. DISC virus-mediated, cytokine gene transfer may prove to be useful as a clinical therapy for head and neck cancers.

• 전기전자학회논문지
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• 제19권1호
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• pp.64-72
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• 2015

본 연구에서는 연료 필터의 생산성 향상을 위하여 IT기반의 갱추리 자동화 장치를 개발한다. 불량 제품의 분석, 수율 개선 및 생산성 향상을 위해 자동화 장치와 연동된 IT 기반의 모니터링 시스템 구축을 구축한다. 3개월간 시료 10,000개 생산시의 불량률 비교 측정한 결과 불량률이 0.65%에서 0.45%로 감소하였다. 또한 공구 모니터링을 통하여 공구 교환 시기의 알림과 로더의 정확한 소재의 수입으로 소재의 불량이 감소하였고, 소재 한 개에 대하여 수입에서 배출까지 공정 시간을 비교한 결과 94.7초에서 78.8초로 감소하여 생산성 증가하였다. 수작업으로 하던 소재의 수입/배출을 자동화로 구축하여 공정시간이 20.2% 감소한다. 또한 작업자 안전과 이송시간 감소는 생산성 향상과 직결된다.

• Archives of Reconstructive Microsurgery
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• 제9권2호
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• pp.134-138
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• 2000

Arthrodesis of the ankle joint is inevitable in the cases of severe arthrosis or defective bony structures around ankle joint. There have been many kinds of arthrodesis methods were introduced. In cases with failed athrodesis with previous arthrodesis surgery and neuropathic joints have difficulty to achieve fusion of joint with conventional methods. Authors underwent four cases of ankle fusion with vascularized fibular graft from 1997 in the cases of three failed fusions and one diabetic neuropatic joint. Two of four performed free vascularized fibular transplantation from contralateral side leg with microvascular anastomosis, two of four performed with pedicled fibular transposition to the ankle joint in same side leg. Three of four cases achieved arthrodesis average 9.2 months after surgery, one case was failed due to vascular thrombosis of the anastomosed site in diabetic neuropathic condition. The result of this technique revealed 75%(three of four) success rate and longer bone union time required. However, in these cases had no recommendable options with conventional bone graft and additional ankle joint fusions procedure because of poor bone quality and defect of distal tibia and talus portions. Free vascualrized fibular transfer to the failed athrodesis of ankle joint is one of the effective alternative methods in failed ankle fusion cases, especially the quality of the bone around previous fusion site is poor.