• Journal of Yeungnam Medical Science
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• v.12 no.2
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• pp.319-330
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• 1995

The influence of normal late pregnancy on insulin action and insulin secretion was studied in the Sprague-Dawley female rats. On 20th day after mating, intravenous glucose tolerance test(IVGTT) was performed in non pregnant control and pregnant rats. As results of IVGTT, glucose disappearance rate was not significantly different in both groups, but secretory response of insulin was significantly(p<0.05) increased in pregnant rat. And the ratio of insulin/glucose was significantly higher in pregnant rats, which means existence of insulin resistance. These insulin resistance was overcomed by increased secretory response of pancreatic insulin. Insulinogenic index(${\Delta}$ insulin/glucose - 5 min) was highly significantly (r=0.62, p<0.01) correlated with progesterone concentration. Glycogen level and amounts of $^{14}C$-glucose incorporated into glycogen after IVGTT were significantly(p<0.05) decreased in the liver, but were not changed significantly in soleus. Glycogen synthase activity of soleus and liver was not differ significantly in the both groups. Insulin binding at varying concentrations of insulin to crude membrane of pregnant liver was not significantly different from control. In conclusions, although these pregnant rats were normal glucose tolerance due to increased secretory response of insulin, that was correlated with progesterone concentration, pregnant rat had insulin resistance. The mechanisms of insulin resistance were not related to defect of insulin binding phase and glycogen synthase, but suggest pre-receptor and/or postreceptor phase.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.482-489
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• 2020

This study conducted a prototype development and evaluation by performing die-casting mold design, mold manufacturing, and injection condition optimization based on flow and solidification analysis to meet the needs of the coupling parts produced by die casting. Through flow analysis, the injection conditions suitable for 100% filling in the cavity were found to be a molten metal temperature of 670 ℃, injection speed of 1.164 m/s, and filling pressure of 6.324~18.77 MPa. In addition, solidification close to 100 % occurred in all four cavities when the solidification rate was 69.47 %. A defect inspection on the surface and inside the product revealed defects, such as poor molding and pores. In addition, the dimensions of the injected product were within the target tolerance and showed good results. Through the feedback of the results of flow and solidification analysis, it was possible to optimize the mold design, and the injection optimization conditions were confirmed to be a total cycle time of approximately 6.5 seconds. Good quality carrier parts with an average surface hardness of approximately 45 mm from the gate measured at 97.48(Hv) could be produced.

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2005.11a
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• pp.147-151
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• 2005

CAN(Controller Area Network) is a simple and efficient network system for real time control and measurement. As it is not only good at error detection but also strong in electromagnetic interference, CAN has been widely used all over the industries. Basically, CAN needs a master node in charge of sensor data collection, node scheduling for data transmission to a monitoring system and error detection. According to the number of mater nodes, the CAN system is classified into two type of master system. One is a single master system that has only one master node and the other is a multi-master system where any sensor node can become a master node depending on the system's conditions. While it has the advantage of its fault tolerance, the multi-master system will suffer form the overall performance degradation when a defect is found in the master node. It is because all sensor nodes pertaining to a defective master node lose their position. Moreover, it is difficult and expensive to implement. For a single master system, the whole system will be broken down when a problem happens to a single master. In this paper, a dynamic master system is presented that there are several sub-master nodes of which basic functions are those of other sensor nodes at ordinary times but dynamically changed to replace the failing master node. An effective scheduling algorithm is also proposed to choose an appropriate node among sub-master nodes, where each sub-master node has its precedence value. The performance of the dynamic master system is experimented and analyzed.

• Korean Journal of Clinical Laboratory Science
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• v.36 no.2
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• pp.121-126
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• 2004

The primary goal of six sigma is to improve patient satisfaction, and thereby profitability, by reducing and eliminating defects. Defects may be related to any aspect of customer satisfaction: high product quality, schedule adherence, cost minimization, process capability indices, defects per unit, and yield. Many six sigma metrics can be mathematically related to the others. Literally, six means six standard deviations from the mean or median value. As applied to quality metrics, the term indicates that failures are at least six standard deviations from the mean or norm. This would mean about 3.4 failures per million opportunities for failure. The objective of six sigma quality is to reduce process output variation so that on a long term basis, which is the customer's aggregate experience with our process over time, this will result in no more than 3.4 defect Parts Per Million(PPM) opportunities (or 3.4 Defects Per Million Opportunities. For a process with only one specification limit (upper or lower), this results in six process standard deviations between the mean of the process and the customer's specification limit (hence, 6 Sigma). The results of applicative six sigma experiment studied on 18 items TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA tests in clinical chemistry were follows. Assessment of process performance fits within six sigma tolerance limits were TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA with 72.2%, items that fit within five sigma limits were total bilirubin, chloride and sodium were 3 sigma. We were sure that the goal of six sigma would reduce test variation in the process.

• Korean Journal of Optics and Photonics
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• v.17 no.5
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• pp.420-429
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• 2006

In the zoom lens of digital still cameras with the variation of the image plane generated by various symmetric error factors such as curvature, thickness and refractive index error of each lens surface about the optic axis, we induce a theoretical condition to fix constantly the image plane by translating the compensator group of the zoom lens by using the Gaussian bracket. We confirm the validity of this condition by using three examples of general zoom lens types with 3, 4, and 5 groups, respectively. When these error factors are randomly changed within the range of tolerance according to the Monte Carlo method, we verify that the distributions of the degree of moving of the compensator are normal distributions at three zoom lens types. From capability analysis using these results, we theoretically propose the method estimating the standard deviation, that is, sigma-level, as a function of the maximum movement of the compensator.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.5
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• pp.344-357
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• 2019

Operational failures may occur even though there had been no signs of defect during the manufacturing process, which may be caused due to exposure to environmental stress which had not been addressed properly during the design process. It is thus necessary to perform environmental testing to determine the cause of the failures. Environmental testing is also used to determine whether a materiel has enough tolerance to the environmental stress during its operation. In this study, the method and level for each environmental testing are properly tailored and applied to a fight aircraft intended to operate in ROK (Republic of Korea), based on the MIL-STD-810G Change 1. Since each part of a fighter aircraft may be exposed to each different environment, LRUs (Line Replaceable Units) exposed to similar environment should be tested similarly. In addition, the decision whether to apply specific test and the tailoring technique in test level were derived for natural and induced environments, respectively. As a fight aircraft is assumed to operate in ROK, the tailoring of test methods and test level to fit to the environment in Korean peninsula is necessary. Further research is needed in determining a specific procedure and a specific level in a test method, and also in determining the test sequence, when conducting more than one is needed, because it can alter test results and it hence becomes an essential element in test design.