• 디지털산업정보학회논문지
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• 제10권4호
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• pp.19-27
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• 2014

Software reliability in the software development process is an important issue. Software process improvement helps in finishing with reliable software product. Infinite failure NHPP software reliability models presented in the literature exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates per fault. In this paper, proposes the reliability model with log type mean value function (Musa-Okumoto and log power model), which made out efficiency application for software reliability. Algorithm to estimate the parameters used to maximum likelihood estimator and bisection method, model selection based on mean square error (MSE) and coefficient of determination($R^2$), for the sake of efficient model, was employed. Analysis of failure using real data set for the sake of proposing log type mean value function was employed. This analysis of failure data compared with log type mean value function. In order to insurance for the reliability of data, Laplace trend test was employed. In this study, the log type model is also efficient in terms of reliability because it (the coefficient of determination is 70% or more) in the field of the conventional model can be used as an alternative could be confirmed. From this paper, software developers have to consider the growth model by prior knowledge of the software to identify failure modes which can be able to help.

• The Korean Journal of Physiology and Pharmacology
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• 제2권3호
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• pp.287-295
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• 1998

Diazepam is known to have cardiovascular depressive effects through a combined action on benzodiazepinergic receptor and the GABA receptor-chloride ion channel complex. Moreover, it is known that barbiturates also have some cardiovascular regulatory effects mediated by the central GABAergic system. Therefore, this study was undertaken to delineate the regulatory actions and interactions of these systems by measuring the responses of the cardiovascular system and renal nerve activity to muscimol, diazepam and pentobarbital, administered intracerebroventricularly in rabbits. When muscimol $(0.03{\sim}0.3\;{\mu}\;g/kg)$, diazepam $(10{\sim}100\;{\mu}\;g/kg)$ and pentobarbital $(1{\sim}10\;{\mu}\;g/kg)$ were injected into the lateral ventricle of the rabbit brain, there were similar dose-dependent decreases in blood pressure (BP) and renal nerve activity (RNA). The relative potency of the three drugs in decreasing BP and RNA was muscimol ＞ pentobarbital ＞ diazepam. Muscimol and pentobarbital also decreased the heart rate in a dose-dependent manner; however, diazepam produced a trivial, dose-independent decrease in heart rate. Diazepam $(30\;{\mu}g/kg)$ augmented the effect of muscimol $(0.1\;{\mu}g/kg)$ in decreasing blood pressure and renal nerve activity, but pentobarbital $(3\;{\mu}g/kg)$ did not. Bicuculline $(0.5\;{\mu}g/kg)$, a GABAergic receptor blocker, significantly attenuated the effect of muscimol in decreasing BP and RNA, either alone or with diazepam, and that of pentobarbital in decreasing BP and RNA, either alone or with muscimol. We inferred that the central benzodiazepinergic and barbiturate systems help regulate peripheral cardiovascular function by modulating the GABAergic system, which adjusts the output of the vasomotor center and hence controls peripheral sympathetic tone. Benzodiazepines more readily modulate the GABAergic system than barbiturates.

• The Korean Journal of Physiology and Pharmacology
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• 제27권2호
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• pp.143-155
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• 2023

Percutaneous coronary intervention and acute coronary syndrome are both closely tied to the frequently occurring complication of coronary microembolization (CME). Resveratrol (RES) has been shown to have a substantial cardioprotective influence in a variety of cardiac diseases, though its function and potential mechanistic involvement in CME are still unclear. The forty Sprague-Dawley rats were divided into four groups randomly: CME, CME + RES (25 mg/kg), CME + RES (50 mg/kg), and sham (10 rats per group). The CME model was developed. Echocardiography, levels of myocardial injury markers in the serum, and histopathology of the myocardium were used to assess the function of the cardiac muscle. For the detection of the signaling of TLR4/MyD88/NF-κB along with the expression of pyroptosis-related molecules, ELISA, qRT-PCR, immunofluorescence, and Western blotting were used, among other techniques. The findings revealed that myocardial injury and pyroptosis occurred in the myocardium following CME, with a decreased function of cardiac, increased levels of serum myocardial injury markers, increased area of microinfarct, as well as a rise in the expression levels of pyroptosis-related molecules. In addition to this, pretreatment with resveratrol reduced the severity of myocardial injury after CME by improving cardiac dysfunction, decreasing serum myocardial injury markers, decreasing microinfarct area, and decreasing cardiomyocyte pyroptosis, primarily by blocking the signaling of TLR4/MyD88/NF-κB and also reducing the NLRP3 inflammasome activation. Resveratrol may be able to alleviate CME-induced myocardial pyroptosis and cardiac dysfunction by impeding the activation of NLRP3 inflammasome and the signaling pathway of TLR4/MyD88/NF-κB.

• Nutrition Research and Practice
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• 제14권5호
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• pp.490-500
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• 2020

BACKGROUND/OBJECTIVES: A cross-sectional study was undertaken to evaluate fluid intake and hydration status in association with cognitive function among 230 adolescents (10-14 years of age) in Petaling Perdana, Selangor, Malaysia. SUBJECTS/METHODS: Urine color was used to measure hydration status, while fluid intake was assessed using the 15-item beverage intake questionnaire. Cognitive function was assessed using the Wechsler Intelligence Scale for Children, Fourth Edition. RESULTS: More than half of the adolescents were mildly or moderately dehydrated (59.6%) and only one-third (33.0%) were well hydrated. Among the daily fluid types, intakes of soft drinks (r = -0.180; P = 0.006), sweetened tea (r = -0.184; P = 0.005) and total sugar-sweetened beverages (SSBs) (r = -0.199; P = 0.002) were negatively correlated with cognitive function. In terms of hydration status, cognitive function score was significantly higher (F-ratio = 4.102; P = 0.018) among hydrated adolescents (100.38 ± 12.01) than in dehydrated (92.00 ± 13.63) counterparts. Hierarchical multiple linear regression analysis, after adjusting for socio-demographic factors, showed that soft drinks (β = -0.009; P < 0.05) and sweetened tea (β = -0.019; P < 0.05) negatively predicted cognitive function (ΔR² = 0.044). When further control for sources of fluid, hydration status (β = -2.839; P < 0.05) was shown to negatively predict cognitive function (ΔR² = 0.021). The above variables contributed 20.1% of the variance in cognitive function. CONCLUSIONS: The results highlight the links between fluid intake (soft drinks, sweetened tea, total SSBs) and hydration status with cognitive function in adolescents. Interventions aimed at decreasing the consumption of SSBs and increasing hydration status through healthy fluid choices, such as water, could improve cognitive performance in adolescents.

• 대한전자공학회논문지TC
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• 제47권11호
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• pp.59-68
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• 2010

본 논문은 보상함수 수정을 통해 보다 완벽한 DSA(Dynamic Spectrum Access)를 수행하는 새로운 방법을 제시하였다. POMDP(Partially Observable Markov Decision Process)는 미래의 스펙트럼 상태를 예측하는데 사용되는 알고리즘으로서, 그 중 보상함수는 스펙트럼을 예측하는데 있어 가장 중요한 부분이다. 그러나 보상함수는 Busy 및 Idle의 두 가지 상태만 갖고 있기 때문에 채널에서 충돌이 발생하게 되면 보상함수는 Busy를 반환함으로써 2차 사용자의 성능을 감소시키게 된다. 따라서 본 논문에서는 기존의 Busy를 Busy 및 Collision 의 두 상태로 구분하였고, 이렇게 추가된 Collision 상태를 통해 2차 사용자의 채널 접근 기회를 보다 향상시킴으로서 데이터 전송율을 증대시킬 수 있도록 하였다. 또한 본 논문은 새로운 알고리즘의 신뢰도 벡터를 수학적으로 분석하였다. 마지막으로 시뮬레이션 결과를 통해 개선된 보상함수의 성능을 검증하고, 이를 통해 새로운 알고리즘이 CR 네트워크에서 2차 사용자의 성능을 향상시킬 수 있음을 보인다.

• 대한공업교육학회지
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• 제34권1호
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• pp.238-251
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• 2009

배열센서에 영향을 주는 자체소음은 그 시스템이 설치된 곳에서 발생하는 소음과 해양으로부터 들어오는 주변소음을 포함한 소음으로 정의된다. 수중에서의 탐지를 위한 배열 구조는 표면을 따라 발생되는 유체 유기소음에 많은 영향을 받는다. 본 논문에서는 곡면배열 음향 센서를 설계하기 위하여 유동유기 소음의 영향으로 인한 주파수 밀도 함수의 적분식의 주요 구성요소인 전달함수(transfer function)를 저파수 영역에서 수치해석 하였다. 난류 경계층에서 발생하는 유입 소음은 수정된 Corcos 모델을 이용하였다. 저파수 영역에서의 전달함수의 특성은 고정판의 두께와 밀도가 작아질수록 함수의 적분값은 적어지므로 소음의 영향은 줄어드는 것으로 나타났다. 또한 Corcos 벽면 압력과 전달함수의 곱에 따른 특성과 주파수 밀도 함수의 곱의 변화를 보였다. 향후 이러한 연구는 무인 잠수정에 탑재할 수 있는 곡면배열 센서의 설계에 응용이 가능하리라 판단된다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 ITC-CSCC -1
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• pp.30-33
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• 2002

To obtain good performance of radial basis function (RBF) neural networks, it needs very careful consideration in design. The selection of several parameters such as the number of centers and widths of the radial basis functions must be considered carefully since they critically affect the network's performance. We propose a learning algorithm for growing of complexity of RBF neural networks which is adapted automatically according to the complexity of tasks. The algorithm generates a new basis function based on the errors of network, the percentage of decreasing rate of errors and the nearest distance from input data to the center of hidden unit. The RBF's center is located at the point where the maximum of absolute interference error occurs in the input space. The width is calculated based on the standard deviation of distance between the center and inputs data. The steepest descent method is also applied for adjusting the weights, centers, and widths. To demonstrate the performance of the proposed algorithm, general problem of function estimation is evaluated. The results obtained from the simulation show that the proposed algorithm for RBF neural networks yields good performance in terms of convergence and accuracy compared with those obtained by conventional multilayer feedforward networks.

• Communications for Statistical Applications and Methods
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• 제24권3호
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• pp.227-240
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• 2017

In this paper, we introduce the inverted exponentiated Weibull (IEW) distribution which contains exponentiated inverted Weibull distribution, inverse Weibull (IW) distribution, and inverted exponentiated distribution as submodels. The proposed distribution is obtained by the inverse form of the exponentiated Weibull distribution. In particular, we explain that the proposed distribution can be interpreted by Marshall and Olkin's book (Lifetime Distributions: Structure of Non-parametric, Semiparametric, and Parametric Families, 2007, Springer) idea. We derive the cumulative distribution function and hazard function and calculate expression for its moment. The hazard function of the IEW distribution can be decreasing, increasing or bathtub-shaped. The maximum likelihood estimation (MLE) is obtained. Then we show the existence and uniqueness of MLE. We can also obtain the Bayesian estimation by using the Gibbs sampler with the Metropolis-Hastings algorithm. We also give applications with a simulated data set and two real data set to show the flexibility of the IEW distribution. Finally, conclusions are mentioned.

• Journal of the Korean Data and Information Science Society
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• 제23권6호
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• pp.1045-1054
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• 2012

서포트벡터 기계는 분류 및 비선형 함수추정에서 유용하게 사용되고 있는 통계적 기법이다. 본 논문에서는 두 개의 입력변수와 회귀함수의 단조 관계를 이용하여 단조 서포트벡터기계를 제안하고, Kaplan-Meier의 방법에 의해서 생존함수의 추정값이 주어진 경우 제안된 방법을 이용하여 생존 함수를 평활하는 방법 또한 제안한다. 모의실험에서는 실제 생존함수를 이용하여 Kaplan-Meier의 방법에 의한 생존함수의 추정값과의 성능을 비교함으로써 제안된 방법의 우수성을 보이기로 한다.

• 대한기계학회논문집
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• 제18권4호
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• pp.1039-1049
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• 1994

The intermitternt and transient fuel spray have been investigated from the simultaneous measurement of droplet sizes and velocities by using Phase/Doppler Particle Analyzer(PDPA). Measurement have been done on the spray axis and at the edge of the spray near nozzle at various gas-to-liquid density ratios(.rho./sub g//.rho./sub l/) that ranges from those found in free atmospheric jets to conditions typical of diesel engines. Probability density distributions of the droplet size and velocity were obtained from raw data and mathematical probability density functions which can fit the experimental distribations were extracted using the principle of maximum likelihood. In the near nozzle region on the spray axis, droplet sizes ranged from the lower limit of the measurement system to the order of nozzle diameter for all (.rho./sub g/ /.rho./sub l/) and droplet sizes tended to be small on the spray edge. At the edge of spray, average droplet velocity peaked during needle opening and needle closing. The rms intensity is greatly incresed as the radial distance from the nozzle is increased. The probability density function which can best fit the physical breakage process such as breakup of fuel drops is exponecially decreasing log-hypebolic function with 4 parameters.