• Title/Summary/Keyword: Decay Curves

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Pole-pole array electrical resistivity survey and an effective interpretational scheme of its data (2극법 전기비저항 탐사 자료의 효율적인 해석방법)

  • Cho Dong-Heng;Lee Chang Yourl;Jee Sang-Keun
    • 한국지구물리탐사학회:학술대회논문집
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    • 2000.09a
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    • pp.112-131
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    • 2000
  • In spite of its many strong points, pole-pole electrode configuration is not often used for ground electrical resistivity survey except for bore hole survey as normal logging and for archaeological investigation. Above all, poor spatial resolution of pole-pole survey may be responsible for this. But recent experiences so far gained by the present authers lead them to think that pole-pole survey can be at least a viable means of reconnaissance survey in near-surface conductive environment and an effective interpretational scheme may augment its resolution. As well known, a response of any other electrode configuration is a linear combination of pole-pole responses. Based on this principle of linear superposition and the principle of reciprocity, the other 'responses' can be derived with simple additions and subtractions of pole-pole responses. Though such responses are not always correct due to the adverse effects of noises, combined with the potential decay curves, they can be helpful to interprete better pole-pole survey data especially in connection of the resolution. This can be comparable to the use of the first or second derivatives of gravity and magnetic intensity surveys.

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The characteristics of chloramine formation and decay with pH variation (pH 변화에 따른 클로라민 생성과 분해 특성)

  • 조관형;김평청;우달식;조영태
    • Journal of Environmental Science International
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    • v.11 no.4
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    • pp.347-353
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    • 2002
  • This study was conducted to investigate the characteristics of chloramination as a secondary disinfection in a drinking water distribution system. At the range from pH 6 to pH 8, monochloramine was predominant with a trace of dichloramine, and the free chlorine was detected after breakpoint. At $25^{\circ}C$, the breakpoints of pH 6, 7 and 8 appeared when the weight ratios of chlorine to ammonia nitrogen were 11:1, 9:1 and 10:1 respectively, and the peak points on the breakpoint curves at pH 6, 7 and 8 were in the Cl$_2$ / NH$_3$-N ratio of 9:1, 6:1 and 5:1 respectively. As pH increased from 6 to 8, maximum point of monochloramine on the breakpoint curve was moved from 7:1 to 5:1 in the weight ratio of chlorine to ammonia nitrogen. The maximum concentration of monochloramine was formed at the pH values of 7~8 and in the Cl$_2$ / NH$_3$-N ratio below 5:1. As the Cl$_2$/NH$_3$-N ratio increased and the pH lowered, chloramines decay proceeded at an increased rate, and residual chloramines lasted longer than the residual free chlorine. The monochloramine and the dichloramine were formed at pH 6, and then the dichloramine continued increasing with contact time.

Pharmacokinetics of Haloperidol (III) -The Pharmacokinetics of Haloperidol after single oral and intravenous doses in schizophrenic patients- (Haloperidol의 약물속도론적 연구 (III) -정신분열증 환자에 있어서 Haloperidol의 일회 주사 및 경구투여시의 Pharmacokinetics-)

  • Park, Kyoung-Ho;Lee, Min-Hwa;Lee, Myung-Gull;Kwon, Jun-Soo;Park, Won-Myung;Park, Jin-Seng
    • YAKHAK HOEJI
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    • v.34 no.6
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    • pp.375-383
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    • 1990
  • The pharmacokinetics of haloperidol were determined after single oral and intravenous doses in 13 male schizophrenic patients. Plasma concentrations of haloperidol(HP) and reduced haloperidol(RH) were measured by high performance liquid chromatography. Plasma concentration data obtained were analyzed by obth model dependent (one-or two exponential decay models using nonlinear regression) and model independent (AUC and first moment curve) approaches. The two methods were found to be in close results. After intravenous injections of HP in 8 patients (10 mg/man), the mean central and peripheral volume of distributions were $2.85\;{\pm}\;1.70$ and $8.09\;{\pm}\;2.10\;l/kg$, respectively, and mean steady state volume of distribution was $11.87\;{\pm}\;3.21\;l/kg$. Mean clearance, MRT and elimination half life were $12.39\;{\pm}\;3.25\;ml/min/kg$, $925.10\;{\pm}\;166.79\;min$ and $676.35\;{\pm}\;126.45\;min$, respectively. After oral administrations of HP in 5 patients, mean peak time and peak concentration were $217.63\;{\pm}\;61.60\;min$ and $9.77\;{\pm}\;2.92\;ng/ml$, respectively. Mean MRT and elimination half life were $1112.23\;{\pm}\;131.73\;min$ and $724.02\;{\pm}\;120.03\;min$, respectively, and these parameters were not significantly different from those of intravenous injection of HP. Absolute bioavailability of HP oral product was found to be about 44%. The profiles of plasma RH concentration-time curves after oral or intravenous doses of HP were similar. Also it was found that the elimination rate of RH was solwer than that of HP by comparing the slopes of plasma concentration-time curves of HP and RH.

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Simulation of Transport and Transformation of Nonconservative Pollutants in Natural Streams: Storage-Transformation Model (자연하천에서 비보존성 오염물질의 이동 및 변환 모의: 저장-변환 모형)

  • Seo, Il Won;Yu, Dae Young
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.14 no.4
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    • pp.867-874
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    • 1994
  • The complex nature of low flow transport and transformation of nonconservative pollutants in natural streams has been investigated using a numerical solution of a proposed mathematical model that is based on a pair of mass balance equations describing the advection, dispersion, decay and mass exchange mechanisms in streams and in storage zones. In the present study, a mathematical model (named "Storage-Transformation Model") has been developed to predict adequately the non-Fickian nature of mixing and transformation mechanisms for decaying substances in natural streams under low flow conditions. Comparisons of the computed concentration-time curves with the measured data show that the Storage-Transformation Model yields better agreements in general shape, peak concentration and time to peak than the conventional 1-D dispersion model. The proposed model shows significant improvement over the 1-D dispersion model in predicting natural transport and transformation processes in streams through pools and riffles.

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Alternating Acquisition Technique for Quantification of in vitro Hyperpolarized [1-13C] Pyruvate Metabolism

  • Yang, Seungwook;Lee, Joonsung;Joe, Eunhae;Lee, Hansol;Song, Ho-Taek;Kim, Dong-Hyun
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.1
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    • pp.53-60
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    • 2016
  • Purpose: To develop a technique for quantifying the $^{13}C$-metabolites by performing frequency-selective hyperpolarized $^{13}C$ magnetic resonance spectroscopy (MRS) in vitro which combines simple spectrally-selective excitation with spectrally interleaved acquisition. Methods: Numerical simulations were performed with varying noise level and $K_p$ values to compare the quantification accuracies of the proposed and the conventional methods. For in vitro experiments, a spectrally-selective excitation scheme was enabled by narrow-band radiofrequency (RF) excitation pulse implemented into a free-induction decay chemical shift imaging (FIDCSI) sequence. Experiments with LDH / NADH enzyme mixture were performed to validate the effectiveness of the proposed acquisition method. Also, a modified two-site exchange model was formulated for metabolism kinetics quantification with the proposed method. Results: From the simulation results, significant increase of the lactate peak signal to noise ratio (PSNR) was observed. Also, the quantified $K_p$ value from the dynamic curves were more accurate in the case of the proposed acquisition method compared to the conventional non-selective excitation scheme. In vitro experiment results were in good agreement with the simulation results, also displaying increased PSNR for lactate. Fitting results using the modified two-site exchange model also showed expected results in agreement with the simulations. Conclusion: A method for accurate quantification of hyperpolarized pyruvate and the downstream product focused on in vitro experiment was described. By using a narrow-band RF excitation pulse with alternating acquisition, different resonances were selectively excited with a different flip angle for increased PSNR while the hyperpolarized magnetization of the substrate can be minimally perturbed with a low flip angle. Baseline signals from neighboring resonances can be effectively suppressed to accurately quantify the metabolism kinetics.

A Study on Self-Similarity in Turbulent Hydrogen Jet Flames with Coaxial Air (동축공기 수소확산 화염의 자기상사성에 대한 연구)

  • Kim, Mun-Ki;Kim, Seung-Han;Yoon, Young-Bin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.5
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    • pp.71-78
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    • 2002
  • Experiments have been performed using two-color PIV in hydrogen non-premixed flames with various conditions of coaxial air, which was classified into three cases with/without reaction. Mean velocity, turbulence intensity and Reynolds stress were analyzed using flow fields from PIV measurement First, the similarity of pure jet had a good agreement with previous results of other researchers. It was found that the decay of centerline velocity was proportional to $x^{-1}$ in coaxial air conditions. By normalizing axial distance with effective jet diameter defined by effective density, the data of centerline velocity collapsed a single line. And the radial profiles of mean velocity showed that they didn't become self-similar because the curves differed from each other as coaxial air velocity increased at fixed fuel velocity. Also, turbulence intensity became self-similar further downstream than mean velocity.

Electrosynthesis of n-PFOSF with Potential Operation (정전위법에 의한 n-PFOSF 합성)

  • Lee, Jongil;Tae, Beomseok
    • Applied Chemistry for Engineering
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    • v.7 no.3
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    • pp.473-480
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    • 1996
  • Synthesis of n-perfluorooctanesulfonyl fluoride(n-PFOSF), which is valuable precursor perfluoro-chemicals, was studied by electrochemical fluorination(ECF). Of prime concern was to investigate the cyclic voltamograms of Ni electrode in anhydrous hydrogen fluoride(AHF) with and without the reactants and to measure fluorine evolution potential. In a batch cell, chronoampherometric electrolysis and various chemical analysis such as GC, GC/MS and IR were used to understand the amphere change of electrode and the reaction paths. Fluorine equilibrium potential was found to be about 2.8V(vs. $Cu/CuF_2$) from the cyclic voltammograms and decay curves of anode potential in AHF. In batch processes, the ECF proceeded in two distinguished steps. The first step proceeded electrochemically and the second one chemically. Under 7V(vs. $Cu/CuF_2$), amount of crude products was proportional to the applied anode potential. Above 7V(vs. $Cu/CuF_2$), it had a hundred percentage with weight ratio of reactants and productivity of PFOSF was almost constant.

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Effect of Number of Measurement Points on Accuracy of Muscle T2 Calculations

  • Tawara, Noriyuki;Nishiyama, Atsushi
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.4
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    • pp.207-214
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    • 2016
  • Purpose: The purpose of this study was to investigate the effect of the number of measurement points on the calculation of transverse relaxation time (T2) with a focus on muscle T2. Materials and Methods: This study assumed that muscle T2 was comprised of a single component. Two phantom types were measured, 1 each for long ("phantom") and short T2 ("polyvinyl alcohol gel"). Right calf muscle T2 measurements were conducted in 9 healthy male volunteers using multiple-spin-echo magnetic resonance imaging. For phantoms and muscle (medial gastrocnemius), 5 regions of interests were selected. All region of interest values were expressed as the mean ${\pm}$ standard deviation. The T2 effective signal-ratio characteristics were used as an index to evaluate the magnetic resonance image quality for the calculation of T2 from T2-weighted images. The T2 accuracy was evaluated to determine the T2 reproducibility and the goodness-of-fit from the probability Q. Results: For the phantom and polyvinyl alcohol gel, the standard deviation of the magnetic resonance image signal at each echo time was narrow and mono-exponential, which caused large variations in the muscle T2 decay curves. The T2 effective signal-ratio change varied with T2, with the greatest decreases apparent for a short T2. There were no significant differences in T2 reproducibility when > 3 measurement points were used. There were no significant differences in goodness-of-fit when > 6 measurement points were used. Although the measurement point evaluations were stable when > 3 measurement points were used, calculation of T2 using 4 measurement points had the highest accuracy according to the goodness-of-fit. Even if the number of measurement points was increased, there was little improvement in the probability Q. Conclusion: Four measurement points gave excellent reproducibility and goodness-of-fit when muscle T2 was considered mono-exponential.

Performance-based and damage assessment of SFRP retrofitted multi-storey timber buildings

  • Vahedian, Abbas;Mahini, Seyed Saeed;Glencross-Grant, Rex
    • Structural Monitoring and Maintenance
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    • v.2 no.3
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    • pp.269-282
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    • 2015
  • Civil structures should be designed with the lowest cost and longest lifetime possible and without service failure. The efficient and sustainable use of materials in building design and construction has always been at the forefront for civil engineers and environmentalists. Timber is one of the best contenders for these purposes particularly in terms of aesthetics; fire protection; strength-to-weight ratio; acoustic properties and seismic resistance. In recent years, timber has been used in commercial and taller buildings due to these significant advantages. It should be noted that, since the launch of the modern building standards and codes, a number of different structural systems have been developed to stabilise steel or concrete multistorey buildings, however, structural analysis of high-rise and multi-storey timber frame buildings subjected to lateral loads has not yet been fully understood. Additionally, timber degradation can occur as a result of biological decay of the elements and overloading that can result in structural damage. In such structures, the deficient members and joints require strengthening in order to satisfy new code requirements; determine acceptable level of safety; and avoid brittle failure following earthquake actions. This paper investigates performance assessment and damage assessment of older multi-storey timber buildings. One approach is to retrofit the beams in order to increase the ductility of the frame. Experimental studies indicate that Sprayed Fibre Reinforced Polymer (SFRP) repairing/retrofitting not only updates the integrity of the joint, but also increases its strength; stiffness; and ductility in such a way that the joint remains elastic. Non-linear finite element analysis ('pushover') is carried out to study the behaviour of the structure subjected to simulated gravity and lateral loads. A new global index is re-assessed for damage assessment of the plain and SFRP-retrofitted frames using capacity curves obtained from pushover analysis. This study shows that the proposed method is suitable for structural damage assessment of aged timber buildings. Also SFRP retrofitting can potentially improve the performance and load carrying capacity of the structure.

Spectral Inversion of Time-domain Induced Polarization Data (시간영역 유도분극 자료의 Cole-Cole 역산)

  • Kim, Yeon-Jung;Cho, In-Ky
    • Geophysics and Geophysical Exploration
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    • v.24 no.4
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    • pp.171-179
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    • 2021
  • We outline a process for estimating Cole-Cole parameters from time-domain induced polarization (IP) data. The IP transients are all inverted to 2D Cole-Cole earth models that include resistivity, chargeability, relaxation time, and the frequency exponent. Our inversion algorithm consists of two stages. We first convert the measured voltage decay curves into time series of current-on time apparent resistivity to circumvent the negative chargeability problem. As a first step, a 4D inversion recovers the resistivity model at each time channel that increases monotonically with time. The desired intrinsic Cole-Cole parameters are then recovered by inverting the resistivity time series of each inversion block. In the second step, the Cole-Cole parameters can be estimated readily by setting the initial model close to the true value through a grid search method. Finally, through inversion procedures applied to synthetic data sets, we demonstrate that our algorithm can image the Cole-Cole earth models effectively.